2018 BCN Advantage Prior Authorization Criteria Last updated: April, 2018

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1 Abstral Actemra Adcirca Adempas Aliqopa Afinitor Afinitor- Disperz Alecensa Alunbrig Amitiza Amitriptyline Ampyra Anadrol-50 Androgel Androderm Aralast NP Aranesp Arcalyst Armodafinil Aubagio Avonex Bavencio Beleodaq Berinert Betaseron Bexarotene Bosulif Briviact Bydureon Byetta Cabometyx Calquence Cayston Cholbam Chorionic Gonadotropin Cimzia Cinryze Clomipramine Cometriq Copaxone Cotellic Crinone Cyramza Daliresp Darzalex Doxepin Duopa Dysport Empliciti Epclusa Epogen Erivedge Esbriet Estradiol Extavia Farydak Fentanyl Oral Fentora Firazyr Forteo Gattex Genotropin Gilenya Gilotrif Glassia Harvoni Hetlioz Humatrope Ibrance Iclusig Idhifa Ilaris Imbruvica Imfinzi Imipramine Increlex Inflectra Inlyta Jakafi Juxtapid Kalydeco Kanuma Kineret Kisqali Kisqali Femara Korlym Kuvan Kynamro Kyprolis Lartruvo Lazanda Lenvima Letairis Lidocaine Transdermal Linzess Lonsurf Lynparza Mavyret Mekinist Menest Modafinil Movantik Mozobil Myalept Mylotarg Natpara Nexavar Nerlynx Ninlaro Norditropin Novarel Nuplazid Nutropin Nutropin Aq Odomzo Ofev Omnitrope Opsumit Orencia, Orencia Clickject Orenitram Orkambi Otezla Oxandrolone Oxymetholone Pegasys Plegridy Pomalyst Praluent Procrit Procysbi Prolastin C Prolia Promacta Radicava Ravicti Rebif Relistor Remicade Remodulin Repatha Revatio Revlimid Rubraca Rydapt Saizen Samsca Serostim Sildenafil Simponi Sirturo Somavert Sovaldi Sprycel Stelara Strensiq Subsys Sutent Sylatron Sylvant SymlinPen Tabloid Tafinlar Tagrisso Tarceva Targretin Tasigna Tecentriq Tecfidera Testim Testosterone Tetrabenazine Thalomid Thioridazine Tracleer Treanda Trimipramine Tysabri Uptravi Vecamyl Vectibix Vemlidy Venclexta Verzenio Victoza Vosevi Votrient Xalkori Xeljanz Xgeva Xolair Xtandi Xyrem Yondelis Yervoy Zaleplon Zelboraf Zemaira Zejula Zolinza Zorbtive Zurampic Zydelig Zykadia Zytiga 1 of 88 H5883_Ph_Apr18PAlist_NM

2 Actemra Required med info Prescriber restrictions Prescribing physician is a rheumatologist Coverage duration One Year Requires trial of etanercept (Enbrel) and adalimumab (Humira) when these medications are FDA labeled for the Part D coverable medically accepted indication. Adempas Required med info Prescriber restrictions 2 of 88

3 Afinitor Required med info Prescriber restrictions Prescriber is an oncologist Coverage is not provided when Affinitor is used in combination with Nexavar or Sutent Aliqopa Effective Date: March 1, 2018 Required med info Prescriber restrictions Coverage duration One year 3 of 88

4 Alecensa Required med info Prescriber restrictions Coverage duration Lifetime Alunbrig Required med info Prescriber restrictions 4 of 88

5 Amitzia Required med info Diagnosis: 1. Chronic idiopathic constipation (CIC) in adults or 2. Opioid induced constipation in adults with chronic, non cancer pain or 3. Irritable bowel syndrome (IBS) with constipation in women Age restrictions 18 years of age and older Prescriber restrictions Ampyra Documentation of trial/failure within the last 12 months of: 1. A fiber laxative and 2. One of the following: a stimulant laxative or an osmotic laxative Exclusion criteria Patients with a history of seizure or moderate to severe renal impairment defined by a crcl of 50ml/min or less Required med info Initial requests require documentation of a 25 foot timed walk test. Renewal requests require documentation of improvement in walking distance of a 25 foot timed walk test compared to pretreatment. Prescriber restrictions Prescriber is a neurologist Coverage duration INITIAL = Three Months RENEWAL = One Year 5 of 88

6 Initial coverage is provided to improve walking distance in patients with a diagnosis of multiple sclerosis who have the ability to walk a timed 25 foot walk test. renewal criteria: documentation that the member has shown an improvement in walking distance of a 25 foot timed walk test compared to pretreatment. Transdermal Androgens Androgel, Androderm, Testim, Testipel, Testosterone Required med info Documentation of androgen deficiency syndrome confirmed by two morning testosterone levels less than 300 ng/dl and at least 2 clinical signs or symptoms specific to androgen deficiency Prescriber restrictions 6 of 88

7 ALPHA-1-PROTEINASE INHIBITOR (Aralast NP, Glassia, Prolastin C, Zemaira) Required med info Prescriber restrictions Arcalyst Required med info Age restrictions 12 years of age and older Prescriber restrictions 7 of 88

8 Aubagio Required med info Prescriber restrictions Avonex Required med info Prescriber restrictions Coverage duration Lifetime 8 of 88

9 Bavencio Required med info Prescriber restrictions Coverage duration Lifetime Beleodaq Required med info Prescriber restrictions 9 of 88

10 Berinert Required med info Prescriber restrictions Prescribing physician is an immunologist or hematologist Betaseron Required med info Prescriber restrictions Coverage duration Lifetime 10 of 88

11 Bosulif Required med info Prescriber restrictions Briviact Required med info Prescriber restrictions 11 of 88

12 Cabometyx Required med info Prescriber restrictions Calquence Effective Date: March 1, 2018 Required med info Prescriber restrictions 12 of 88

13 Cayston Required med info Prescriber restrictions Cayston is subject to Part B versus Part D coverage review Cholbam Required med info Prescriber restrictions 13 of 88

14 Chorionic Gonadotropin Required med info Prescriber restrictions 14 of 88

15 Cimzia Required med info Requires documentation of diagnosis and medication history or intolerance(s) Prescriber restrictions Crohn's Disease: Prescribed or recommended by a gastroenterologist RA: Prescribed or recommended by a rheumatologist. Rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis requires the member has tried and failed Humira and Enbrel, except if not tolerated due to documented clinical side effects. Crohn's disease, requires: 1) treatment with an adequate course of systemic corticosteroids (e.g., 40 mg to 60 mg prednisone per day for 7 to 14 days) has been ineffective or is contraindicated or 2) the patient has been unable to taper off an adequate course of systemic corticosteroids without experiencing worsening of disease or 3) the patient is experiencing breakthrough disease (e.g., active disease flares) while stabilzed for at least 2 months on an immunomodulatory medication (such as azathioprine, mercaptopurine, cyclosporine, or methotrexate) and 4) adalimumab (Humira) is not effective after at least an initial 3 dose induction period, except if not tolerated due to documented clincial side effects. 15 of 88

16 Cinryze Required med info Prescriber restrictions Prescribed by an immunologist, allergist, or rheumatologist Cometriq Required med info Prescriber restrictions 16 of 88

17 Copaxone Required med info Prescriber restrictions Coverage duration Lifetime Cotellic Required med info Prescriber restrictions Coverage duration Lifetime 17 of 88

18 Crinone Required med info Prescriber restrictions Cyramza Required med info Prescriber restrictions Coverage duration Lifetime 18 of 88

19 Daliresp Required med info Diagnosis and patient medication history Prescriber restrictions Coverage is provided for the treatment of severe chronic obstructive pulmonary disease (COPD) associated with chronic bronchitis in patients with a history of exacerbations and patient is receiving: 1. inhaled long acting beta 2 agonist [for example, Formoterol, Salmeterol] AND 2. inhaled long acting anticholinergic agent [for example, Tiotropium] AND 3. inhaled corticosteroid [for example, Fluticasone] OR 4. Patient experienced intolerance or has contraindications to use of these medications Darzalex Required med info Prescriber restrictions Coverage duration Lifetime 19 of 88

20 Duopa Required med info Prescriber restrictions Subject to Part B versus D coverage review. Duopa may be covered under Medicare Part B if the patient is receiving enteral suspension administered as a continuous infusion using a portable infusion pump. It may be covered under Medicare Part D if the patient is receiving enteral suspension short term via a naso jejunal tube 20 of 88

21 Dysport Exclusion criteria Will not be covered for cosmetic purposes Required med info Prescriber restrictions Empliciti Required med info Prescriber restrictions Coverage duration Lifetime 21 of 88

22 Epclusa Required med info CRITERIA WILL BE APPLIED CONSISTENT WITH CURRENT AASLD/IDSA GUIDANCE Prescriber restrictions Coverage duration CRITERIA WILL BE APPLIED CONSISTENT WITH CURRENT AASLD/IDSA GUIDANCE CRITERIA WILL BE APPLIED CONSISTENT WITH CURRENT AASLD/IDSA GUIDANCE Erythropoesis Stimulating Agents: Aranesp, Epogen, Procrit Required med info Prescriber restrictions Coverage duration 3 months Erythropoesis stimulating agents are subject to Part B vs Part D review. 22 of 88

23 Erivedge Required med info Prescriber restrictions Prescribed by or in consultation with a dermatologist or oncologist Esbriet Required med info Prescriber restrictions 23 of 88

24 Estrogens (Estradiol, Menest) Required med info Age restrictions Authorization is required for members 65 years of age and older Prescriber restrictions Oral Estrogen (Menest) will be approved when used as part of a cancer treatment regimen. For all other uses, Menest will be approved if two of the following safer alternatives as been tried and failed or are not appropriate or contraindicated. Safer alternatives include: e.g., SSRIs, venlafaxine ER, Premarin vaginal cream, Estrace vaginal creams, Estring or Femring Vaginal Rings, Vagifem vaginal tablets 24 of 88

25 Extavia Required med info Prescriber restrictions Coverage duration Lifetime Farydak Required med info Prescriber restrictions 25 of 88

26 Firazyr Covered uses Exclusion criteria Required med info Age restrictions Prescriber restrictions Coverage duration For acute attacks of hereditary angioedema (HAE). All FDA approved indications not otherwise excluded from Part D. 18 years of age or older Prescribing physician is an immunologist or hematologist One Year Forteo Exclusion criteria Coverage is not provided for hypocalcemia Required med info Prescriber restrictions Coverage duration One year with maximum two years of therapy Requires patient has tried and failed at least one bisphosphonate except when: 1. Contraindication to an oral and intravenous bisphosphonate (such as a stricture or aclasia, inability to stand or sit upright for at least 30 minutes and increased risk of aspiration) 2. Documented intolerance to a bisphosphonate 26 of 88

27 Gattex Required med info Prescriber restrictions Coverage duration Lifetime Gilenya Required med info Prescriber restrictions 27 of 88

28 Giltorif Required med info Prescriber restrictions Harvoni Required med info Prescriber restrictions Coverage duration Criteria will be applied consistent with current AASLD/IDSA guidance Criteria will be applied consistent with current AASLD/IDSA guidance 28 of 88

29 Growth Hormone: Genotropin, Humatrope, Increlex, Norditropin, Nutropin, Nutropin AQ, Omnitrope, Saizen, Serostim, Somavert, Zorbtive Required med info Covered for the replacement of endogenous growth hormone in adults with growth hormone deficiency of childhood onset or adult onset. Covered if initial diagnosis based on two growth hormone stimulation tests and that the patient does not have edema, arthralgias, or carpal tunnel syndrome. Serostim is covered for aids wasting cachexia. Norditropin is covered for Noonan syndrome, Turner syndrome, and adult growth hormone deficiency. Nutropin is covered for Turner syndrome, and adult growth hormone deficiency. Omnitrope and Saizen are covered for adult growth hormone deficiency. Zorbtive is covered for the treatment of short bowel syndrome in patients receiving specialized nutritional support. Somavert is covered for acromegaly. Prescriber restrictions 29 of 88

30 Hetlioz Required med info Documentation of patient visual capabilities Prescriber restrictions Coverage duration Lifetime Hepatitis Treatments: Pegasys, Pegasys proclick Required med info Documentation of concomitant Ribavarin use (or contraindications) is required when requesting initial use for Hepatitis C. Documentation of viral genotype is required for Hepatitis C. Documentation of response to therapy is required for requests for continuation of therapy for Hepatitis C Prescriber restrictions Coverage duration Initiation of Therapy: 12 weeks Continuation Therapy: 24 to 48 weeks 30 of 88

31 High Risk in the Elderly Medications: High Risk in the Elderly Drugs: Tricyclic Antidepressants: Amitriptyline, Clomipramine, Doxepin, Imipramine, Trimipramine Required med info Age restrictions Authorization is required for formulary high risk medications for members 65 years of age and older Prescriber restrictions High Risk Tricyclic Antidepressants are approved if patient has a history of use. For patients initiating therapy, the high risk tricyclic antidepressant is approved if at least one of the suggested alternatives (nortriptyline, desipramine, citalopram, escitalopram, mirtazapine, sertraline, venlafaxine) with less sedation and fewer anticholinergic effects have been tried and failed or is not appropriate or contraindicated for the intended use. 31 of 88

32 High Risk in the Elderly Medications: Zaleplon Required med info Age restrictions Authorization is required for formulary high risk medications for members 65 years of age and older Prescriber restrictions Lunesta (Zaleplon) is approved if at least one of the suggested alternatives, (low dose Trazodone (25 50mg) or Rozerem), has been tried and failed or is not appropriate or contraindicated for the intended use. High Risk in the Elderly Medications: Thioridiazine Required med info Age restrictions Prior authorization is required for formulary high risk medications for members 65 years of age and older Prescriber restrictions Thioridizine is covered for patients who have a history of use. For patients initiating therapy, thioridizine is covered if patient has a failure of or intolerance to at least one other safer alternative antipsychotic such as aripiprazole or quetiapine. 32 of 88

33 Ibrance Required med info Prescriber restrictions Iclusig Required med info Prescriber restrictions 33 of 88

34 Idhifa Effective Date: March 1, 2018 Required med info Prescriber restrictions Ilaris Required med info Requires documentation of diagnosis. Prescriber restrictions 34 of 88

35 Imbruvica Required med info Prescriber restrictions Imfinzi Required med info Prescriber restrictions 35 of 88

36 Inflectra Required med info Prescriber restrictions 36 of 88

37 Injectable Diabetic Medications: Byetta, Bydureon, Victoza, SymlinPen Exclusion criteria Not covered for non Type 2 diabetes diagnosis. Not covered for weight loss in patients with or without diabetes. Required med info Prescriber restrictions Coverage duration Lifetime Byetta, Bydureon, Victoza: Approved as adjunctive therapy to improve glycemic control in patients who have a diagnosis of Type II Diabetes Mellitus and are currently taking or have tried and failed at least One of the following: Metformin, a Sulfonylurea, or a Thiazolidinedione, or One of the following: a combination of metformin and a sulfonylurea or a combination of Metformin and a Thiazolidinedione. SymlinPen is covered for patients that have failed intensive treatment with insulin monotherapy and for concurrent use with an insulin product 37 of 88

38 Inlyta Exclusion criteria Coverage is not provided for combination use with other tyrosine kinase inhibitors such as Sorafenib, Sunitinib Required med info Coverage for the treatment of renal cell carcinoma is provided after failure with one prior systemic therapy Prescriber restrictions Jakafi Required med info Prescriber restrictions Prescribed by a hematologist / oncologist 38 of 88

39 Juxtapid Required med info Requires documentation of diagnosis of homozygous familial hypercholesterolemia. Age restrictions Prescriber restrictions Coverage duration Lifetime Requires trial and failure of Kynamro Kalydeco Required med info Prescriber restrictions Coverage duration Lifetime 39 of 88

40 Kanuma Required med info Prescriber restrictions Kineret Required med info Prescriber restrictions Rheumatoid arthritis requires a treatment failure or contraindication to Enbrel or Humira. 40 of 88

41 Kisqali, Kisqali Femara Required med info Prescriber restrictions Korlym Required med info Prescriber restrictions 41 of 88

42 Kynamro Required med info Prescriber restrictions Coverage duration Lifetime Kyprolis Required med info Prescriber restrictions Coverage duration Lifetime 42 of 88

43 Lartruvo Effective Date: March 1, 2018 Required med info Prescriber restrictions Coverage duration Lifetime Lenvima Required med info Prescriber restrictions 43 of 88

44 Lidocaine Transdermal Patch Required med info Prescriber restrictions Linzess Required med info Prescriber restrictions Chronic idiopathic constipation (CIC) requires documentation of failure within the last 12 months of use of a fiber laxative and one of the following: a stimulant laxative or an osmotic laxative. Drug induced constipation must be ruled out. 44 of 88

45 Lonsurf Required med info Prescriber restrictions Coverage duration Lifetime Lynparza Required med info Prescriber restrictions 45 of 88

46 Mavyret Effective Date: March 1, 2018 Required med info Prescriber restrictions Mekinist Required med info Confirmation of the presence of BRAF V600E or V600K mutation in tumor specimen Prescriber restrictions 46 of 88

47 Modafinil, Armodafinil Required med info Prescriber restrictions Movantik Required med info Prescriber restrictions 47 of 88

48 Mozobil Required med info Prescriber restrictions Coverage duration Duration requested up to one month Myalept Exclusion criteria Coverage is not provided for the following: general obesity, HIV related lipodystrophy, partial lipodystrophy, metabolic disease (without concurrent generalized lipodystrophy) or liver disease. Required med info Diagnosis of congenital or acquired generalized lipodystrophy Prescriber restrictions Prescribing physician is an endocrinologist Coverage duration Initial = 3 months Renewal = 1 year 48 of 88

49 Mylotarg Effective Date: March 1, 2018 Required med info Prescriber restrictions Narcotic Analgesics: Abstral, Fentanyl Citrate Oral Transmucosal, Fentora, Lazanda, Onsolis, Subsys Required med info Requires documentation of diagnosis and medication history Prescriber restrictions Covered for cancer or cancer related diagnosis in patients already receiving long acting opioids 49 of 88

50 Natpara Required med info Prescriber restrictions Nerlynx Effective Date: March 1, 2018 Required med info Prescriber restrictions 50 of 88

51 Nexavar Required med info Prescriber restrictions Hepato cellular carcinoma: Prescribed by an oncologist, hepatologist, or gastroenterologist All other indications: Prescribed by an oncologist Ninlaro Required med info Prescriber restrictions Coverage duration Lifetime 51 of 88

52 Nuplazid Required med info Prescriber restrictions Odomzo Required med info Prescriber restrictions Coverage duration Lifetime 52 of 88

53 Ofev Required med info Prescriber restrictions Coverage duration One year Orencia, Orencia Clickject Required med info Prescriber restrictions Coverage is provided when there has been a trial and failure or contraindication to Enbrel or Humira 53 of 88

54 Orenitram Required med info Prescriber restrictions Coverage duration Lifetime Orkambi Required med info Prescriber restrictions Coverage duration Lifetime 54 of 88

55 Otezla Required med info Prescriber restrictions Coverage is provided for moderate to severe plaque psoriasis or psoriatic arthritis when there has been a trial and failure or contraindication to Enbrel or Humira Oxandrolone Covered uses Exclusion criteria Required med info Age restrictions Prescriber restrictions Coverage duration All medically accepted indications not otherwise excluded from Part D One Year 55 of 88

56 Oxymetholone, Anadrol-50 Exclusion criteria Coverage will not be provided if anabolic steroids are used to enhance athletic performance or for anti aging purposes Required med info Oxymetholone: Documentation that use is 1) for therapy to offset protein catabolism associated with prolonged use of corticosteroids. 2) for bone pain associated with osteoporosis. 3) as prophylactic therapy in patients with hereditary angioedema. anadrol 50 requires documentation of:1) HIV associated wasting.2) prophylactic therapy for hereditary angioedema.3) clinically diagnosed anemia. Prescriber restrictions Plegridy Required med info Prescriber restrictions 56 of 88

57 Pomalyst Required med info Diagnosis of multiple myeloma Prescriber restrictions Coverage is provided if: 1) Patient has received at least two prior therapies including Lenalidomide and Bortezomib and 2) Demonstrated disease progression on or within 60 days of completion of the last therapy. Praluent Required med info Prescriber restrictions 57 of 88

58 Procysbi Required med info Prescriber restrictions Coverage duration Lifetime 58 of 88

59 Prolia Exclusion criteria Coverage is not provided for hypocalcemia Required med info Prescriber restrictions Prolia is subject to Part B versus Part D review Requirements: Patient has tried and failed at least one bisphosphonate except when: 1. Contraindication to a bisphosphonate (oral and intravenous) such as a stricture or aclasia, inability to stand or sit upright for at least 30 minutes and increased risk of aspiration 2. Documented intolerance to a bisphosphonate 59 of 88

60 Promacta Required med info Requires documentation of diagnosis, medication history or intolerance(s), platlet counts. Prescriber restrictions Prescribed or recommended by a hematologist, hepatologist or gastroenterologist. Coverage duration Initiation of therapy 12 week approval Continuation therapy 12 month approval Pulmonary Agents: Adcirca, Letairis, Opsumit, Revatio oral suspension, Sildenafil Citrate 20mg, Remodulin, Tracleer Required med info Prescriber restrictions Coverage for Revatio and Adcirca is not provided in situations where patients are receiving nitrate therapy. 60 of 88

61 Radicava Effective Date: March 1, 2018 Required med info Prescriber restrictions Ravicti Required med info Prescriber restrictions 61 of 88

62 Rebif Required med info Prescriber restrictions Coverage duration Lifetime Relistor Required med info Prescriber restrictions Coverage duration Three Months Requires adequate treatment consisting of 5 days duration of treatment of agents for constipation, including at least any two of the following: Bulk laxatives, saline laxatives or osmotic laxatives. Coverage may not be provided if there are contraindications to Methylnaltrexone therapy. 62 of 88

63 Remicade Required med info Verification that the patient has been evaluated for TB and treated accordingly Prescriber restrictions Remodulin Required med info Prescriber restrictions 63 of 88

64 Repatha Required med info Prescriber restrictions Revlimid Required med info Prescriber restrictions Prescribed by or in consultation with an oncologist or hematologist 64 of 88

65 Rubraca Required med info Prescriber restrictions Rydapt Required med info Prescriber restrictions 65 of 88

66 Samsca Required med info Documentation that patient does not have underlying liver disease Prescriber restrictions Coverage duration One Month Kuvan (Sapropterin hydrochloride) Required med info Prescriber restrictions Coverage duration Initial 2 months auth will be extended for 1 year if documented response after initial therapy Renewal criteria: after initial therapy of 2 months. a 30% or greater reduction in phenylalanine from baseline 66 of 88

67 Simponi Required med info Requires verification that the patient has been evaluated for TB and treated accordingly Prescriber restrictions For ulcerative colitis, coverage is provided when the member has tried and failed Humira unless contraindicated or not tolerated due to documented clinical side effects. All other indications for use require the member has tried and failed Humira and Enbrel, except if contraindicated or not tolerated due to documented clinical side effects. Sirturo Required med info Diagnosis Prescriber restrictions Must be used in combination with at least 3 other agents 67 of 88

68 Sovaldi Required med info Prescriber restrictions Coverage duration Criteria will be applied consistent with current AASLD/IDSA guidance Criteria will be applied consistent with current AASLD/IDSA guidance Sprycel Required med info Prescriber restrictions Prescribed by oncologist 68 of 88

69 Stelara Exclusion criteria Crohn's disease Required med info Requires verification that the patient has been evaluated for TB and has been treated accordingly. Prescriber restrictions For Crohn's, coverage is provided when the member has tried and failed Humira unless contraindicated or not tolerated due to documented clinical side effects. All other indications for use require the member has tried and failed Humira and Enbrel, except if contraindicated or not tolerated due to documented clinical side effects. Strensiq Required med info Prescriber restrictions 69 of 88

70 Sutent Required med info Prescriber restrictions Prescribed by oncologist Sylatron Required med info Prescriber restrictions Prescribed by oncologist 70 of 88

71 Sylvant Required med info Prescriber restrictions Tabloid Required med info Prescriber restrictions Prescribed by oncologist or hematologist 71 of 88

72 Tafinlar Required med info Confirmation of the presence of BRAF V600E or BRAF V600K mutation in tumor specimen as detected by an FDA approved test Prescriber restrictions Tagrisso Required med info Prescriber restrictions Coverage duration Lifetime 72 of 88

73 Tarceva Required med info Prescriber restrictions Prescribed by oncologist Targretin/Bexarotene Required med info Prescriber restrictions Prescribed by oncologist or dermatologist 73 of 88

74 Tasigna Required med info Prescriber restrictions Ticfidera Required med info Prescriber restrictions Coverage duration Lifetime 74 of 88

75 Tecentriq Required med info Prescriber restrictions Tetrabenazine Exclusion criteria Coverage for Xenazine or Tetrabenazine will not be provided for patients who have hepatic function impairment, patients who are actively suicidal or who have untreated or inadequately treated depression, or patients taking monoamine oxidase inhibitors or reserpine. Required med info Prescriber restrictions Coverage duration Lifetime 75 of 88

76 Thalomid Required med info Prescriber restrictions Treanda Required med info Prescriber restrictions 76 of 88

77 Tysabri Required med info Prescriber restrictions Coverage is provided for relapsing remitting form of multiple sclerosis when there is documentation of a trial of Copaxone and at least one other interferon beta product unless contraindicated. For Crohns disease coverage is provided with documentation of a trial and failure of Humira and either Cimzia or Stelara Uptravi Required med info Prescriber restrictions 77 of 88

78 Vecamyl Required med info Prescriber restrictions Vectibex Required med info Prescriber restrictions Prescribed by an oncologist 78 of 88

79 Vemlidy Effective Date: April 1, 2018 Required med info Prescriber restrictions Venclexta Required med info Prescriber restrictions Verzenio 79 of 88

80 Effective Date: March 1, 2018 Required med info Prescriber restrictions Vosevi Effective Date: March 1, 2018 Required med info Prescriber restrictions Coverage duration CRITERIA WILL BE APPLIED CONSISTENT WITH CURRENT AASLD/IDSA GUIDANCE. Votrient 80 of 88

81 Required med info Documentation of advanced renal cell carcinoma Prescriber restrictions Prescribed by an oncologist Xalkori Required med info Diagnosis of locally advanced or metastatic non small cell lung cancer (NSCLC) that is anaplastic lymphoma kinase (alk) positive as detected by a FDA approved test. Prescriber restrictions 81 of 88

82 Xeljanz Required med info Requires documentation of diagnosis and medication history or intolerance(s). Prescriber restrictions Prescribed or recommended by a rheumatologist Requires a treatment failure or contraindication to Enbrel and Humira. Xgeva Required med info Prescriber restrictions 82 of 88

83 Xolair Required med info Prescriber restrictions Xtandi Required med info Coverage is provided for the treatment of metastatic castration resistant prostate cancer where the patient has had prior treatment with docetaxel. Prescriber restrictions Prescribed or recommended by an oncologist or urologist 83 of 88

84 Xyrem Required med info Prescriber restrictions Yervoy Required med info Prescriber restrictions Prescribed by an oncologist Yondelis 84 of 88

85 Required med info Prescriber restrictions Coverage duration Lifetime Zejula Required med info Prescriber restrictions Coverage duration Lifetime Zelboraf 85 of 88

86 Exclusion criteria Will not be covered in combination with Yervoy Required med info Prescriber restrictions Prescribed by an oncologist Zolinza Required med info Prescriber restrictions Zurampic 86 of 88

87 Required med info Prescriber restrictions Zydelig Required med info Prescriber restrictions Zykadia 87 of 88

88 Required med info Prescriber restrictions Coverage duration Lifetime Zytiga Required med info Prescriber restrictions 88 of 88

2018 BCN Advantage Prior Authorization Criteria Last updated: November, 2017

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