Chemistry Reference Ranges and Critical Values

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1 Alanine Aminotransferase (ALT, SGPT) 3-9 years 9-18 years 1-9 years 9-18 years U/L U/L U/L Albumin 0-6 days 6 days - 37 months 37 months - 7 years 7-20 years g/dl g/dl g/dl g/dl g/dl Alkaline Phosphatase 3-6 years years 59 years 3-6 years years 59 years U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L Ammonia 0-1 day 1 day - 2 weeks 2 weeks - 18 years µmol/l µmol/l µmol/l µmol/l >107 µmol/l >99 µmol/l >99 µmol/l >99 µmol/l Page 1 of 7

2 Amylase 1-6 months 3-9 years 9-18 years Aspartate Amino- Transferase (AST, SGOT) 0-6 days 6 days - 3 years 3-7 years years years Bilirubin, Direct 1 month Bilirubin, Total 0-1 day 1-2 days 2-5 days 5 days - 20 years Blood Urea Nitrogen (BUN) Calcium, Ionized, Plasma and Whole Blood (Inpatient/ED/Surgery) Calcium, Ionized, Serum (Outreach) 0-6 days 6 days - 20 years years 0-1 day 1-2 days 2 days 0-1 day 1-2 days 2 days Calcium, Total 0-10 days 10 days - 2 years 2-12 years 12 years 0-10 U/L 0-17 U/L 0-44 U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L 5-30 U/L 8-39 U/L mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl 4-12 mg/dl 5-18 mg/dl 6-20 mg/dl 8-23 mg/dl mmol/l mmol/l mmol/l mmol/l mmol/l mmol/l mg/dl mg/dl mg/dl mg/dl Page 2 of 7

3 Carbon Dioxide, Total (CO 2, Bicarbonate) 0-1 week 1 week - 1 month 1 month - 6 months 1-2 years 2-60 years Chloride 1 month - 90 years Cholesterol, Total Cardiac Risk Cardiac Risk CHILDREN & ADOLESCENTS Cholesterol, HDL Cardiac Risk mmol/l mmol/l mmol/l mmol/l mmol/l mmol/l mmol/l mmol/l mmol/l mmol/l Desirable: <200 mg/dl Borderline High: mg/dl High Risk: 240 mg/dl Very High: >280 mg/dl Desirable: <170 mg/dl Borderline High: mg/dl High Risk: 200 mg/dl Desirable: 60 mg/dl High Risk: <40 mg/dl <76 mmol/l <76 mmol/l <76 mmol/l >125 mmol/l >125 mmol/l >125 mmol/l Cholesterol/HDL Ratio All Ages Cholesterol, LDL Cardiac Risk C-Reactive Protein (CRP) C-Reactive Protein, High Sensitivity (hscrp) Cardiac Risk CHILDREN & ADOLESCENTS Desirable: <100 mg/dl Near Optimal: mg/dl Borderline High: mg/dl High Risk: mg/dl Very High: 190 mg/dl Desirable: <110 mg/dl Borderline High: mg/dl High Risk: 130 mg/dl All Ages mg/l All Ages mg/l Page 3 of 7

4 Creatine Kinase, Total (CK, CPK) Creatine Kinase-MB (CK-MB) 0-3 years 3-7 years years years years years U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L All ages 0-6 ng/ml CK-MB Index: 0-4% Creatinine 0-3 days 4 days - 1 month 2 months - 9 years years Creatinine Clearance (U CRC) mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl 0 19 years years years years years years years years 0 19 years years years years years years years years Not established ml/min/1.73m ml/min/1.73m ml/min/1.73m ml/min/1.73m ml/min/1.73m ml/min/1.73m ml/min/1.73m ml/min/1.73m 2 Not established ml/min/1.73m ml/min/1.73m ml/min/1.73m ml/min/1.73m ml/min/1.73m ml/min/1.73m ml/min/1.73m ml/min/1.73m 2 Page 4 of 7

5 Ferritin 1-7 months 7 months - 1 year 1-6 years 6-19 years 19 years Gamma Glutamyl Transferase (Gamma GT, GGT) 1-7 months 7 months - 1 year 1-6 years 6-19 years 19 years 0-6 months 1-12 years years 0-6 months 1-12 years years Glucose 0-1 day 1 day - 1 month 1-60 years years Glucose, CSF 0-2 years 2 years Iron 0-2 days 2 days - 2 years 2-6 years 6 years Iron Binding Capacity, Total (TIBC) Unsaturated Iron Binding Capacity ng/ml ng/ml ng/ml ng/ml ng/ml ng/ml ng/ml ng/ml ng/ml ng/ml ng/ml ng/ml U/L 1-39 U/L 3-22 U/L 2-42 U/L 2-30 U/L U/L 1-39 U/L 4-22 U/L 4-24 U/L 2-24 U/L mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl µg/dl µg/dl µg/dl µg/dl <31 mg/dl <31 mg/dl <40 mg/dl <40 mg/dl Page 5 of 7 >299 mg/dl >299 mg/dl >299 µg/dl >299 µg/dl >299 µg/dl >499 µg/dl All Ages µg/dl All Ages µg/dl % Iron Saturation All Ages 15-50% Lactate, CSF All Ages mmol/l >3.0 mmol/l Lactate, Plasma All Ages Venous: mmol/l Arterial: mmol/l >2.0 mmol/l

6 Lactate Dehydrogenase (LDH) 1-6 years years 3-6 years years U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L U/L Page 6 of 7 Lipase All Ages 7-59 U/L Magnesium 0-6 days 6 days - 1 month 1 month - 2 years 2-7 years years years mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl Magnesium, OB All Ages ng/dl >7.9 mg/dl Phosphorus 1-4 years 4-7 years years years years years 1-4 years 4-7 hears years years mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl

7 16-18 years years Potassium 0-1 year > 1 year mg/dl mg/dl mg/dl mmol/l mmol/l <2.9 mmol/l <2.9 mmol/l >7.4 mmol/l >6.1 mmol/l Protein, CSF All Ages mg/dl >188 mg/dl Protein, Total 0-1 week 1 week - 7 months 7 months - 1 year 3-18 years years Sodium 0-1 year 1-12 years 12 years Triglyceride Cardiac Risk g/dl g/dl g/dl g/dl g/dl g/dl g/dl mmol/l mmol/l mmol/l Desirable: <150 mg/dl Borderline High: mg/dl High Risk: mg/dl Very High: 500 mg/dl Troponin I All Ages No detectable cardiac injury: 0.03 ng/ml Possible cardiac muscle injury (8 hours post symptom onset: 86% sensitivity and 94% specificity for MI): 0.04 to 0.49 ng/ml Myocardial infarction (MI): 0.50 ng/ml Uric Acid 0-6 days 6 days - 3 years 3-7 years years years years mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl mg/dl <126 mmol/l <121 mmol/l <121 mmol/l >149 mmol/l >159 mmol/l >159 mmol/l 0.50 ng/ml Reference ranges are subject to update. Refer to the individual test listed on the Legacy web site or the patient chart for reference ranges at time of testing. Page 7 of 7

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