CASE 01 LA Path Slide Seminar 13 March, 08. Deepti Dhall, MD Department of Pathology and Laboratory Medicine Cedars-Sinai Medical Center
|
|
- Ross Horn
- 6 years ago
- Views:
Transcription
1 CASE 01 LA Path Slide Seminar 13 March, 08 Deepti Dhall, MD Department of Pathology and Laboratory Medicine Cedars-Sinai Medical Center
2 Clinical History 60 year old male presented with obstructive jaundice CT scan showed an ill-defined 4cm mass in the head of the pancreas FNA was inconclusive The patient underwent whipple resection
3
4
5
6
7
8
9
10 Lymphoplasmacytic sclerosing Pancreatitis (LPSP) Autoimmune pancreatitis
11 First described by Sarles in 1961 as primary inflammatory sclerosing pancreatitis Yoshida in 1995 used the term autoimmune pancreatitis Association with autoimmune diseases (30% of cases) Supporting laboratory finding Sarles et al. Am J Dig Dis Jul;6: Yoshida et al. Dig Dis Sci Jul;40(7):
12 Distinct clinicopathological features: Clinical presentation is misleading, mimics pancreatic carcinoma Characteristic histological features May respond to steroids True incidence is not known 5% to 11% of all patients with chronic pancreatitis
13 Clinical Features Typically affects middle aged patients No history of alcohol abuse Associated with autoimmune diseases Usually presents with jaundice and abdominal pain Severe abdominal pain of acute pancreatitis is lacking
14 Radiological findings ERCP, ultrasound and CT reveal segmental stenosis of the pancreatic ducts distal bile duct stricture diffuse pancreatic enlargement ill-defined mass
15
16 LPSP Adenocarcinoma
17 Histological features Dense periductal lymphoplasmacytic infiltrate Interstitial and periductal fibrosis
18 Vein Histological features Venulitis NO Fat necrosis Calcifications Pseudocysts Vein
19 Diagnostic criteria for autoimmune pancreatitis proposed by Japanese Pancreas Society (2002) 1. Pancreatic imaging studies show diffuse narrowing of the main pancreatic duct with irregular wall (more than 1/3 of length of the entire pancreas) 2. Laboratory data demonstrate abnormally elevated levels of serum gamma globulin and/or IgG 4, or the presence of autoantibodies 3. Histopathologic examination of the pancreas shows fibrotic changes with lymphocyte and plasma cell infiltrate.
20 Subtypes of LPSP LPSP, classical type LPSP with granulocytic epithelial lesions (GELs) / Idiopathic ductcentric chronic pancreatitis (IDCP). Notahara et al. Am J Surg Pathol. 27: , 2003 Zamboni et al. Virchows Arch. 445; , 2004
21 Histological subtypes Type of LPSP Age Sex Associated autoimmune disease Recurrence After resection LPSP, classical 60 s M>F Sjogren s syndrome More common LPSP with GELs Mid 40 s M=F Inflammatory bowel disease Less common
22 LPSP vs. Alcoholic Chronic Pancreatitis Histological Finding Involved ducts Inflammation Venulitis Calculi Pseudocysts LPSP Medium sized interlobular ducts Dense, periductal Present No No Alcoholic chronic pancreatitis Large interlobular ducts Sparse, scattered Absent Yes Yes Modified from: Ectors et al. Gut 41:263-8, 1997
23
24 LPSP Peri-tumoral pancreatitis
25 High serum IgG4 concentrations in patients with sclerosing pancreatitis. Hamano et al. N Engl J Med Mar 8;344(10): Sensitivity 95% Specificity 97%
26 LPSP, CLASSICAL
27 Non-specific Adenocarcinoma
28
29 Endoscopic ultrasound guided fine needle aspiration biopsy of autoimmune pancreatitis: diagnostic criteria and pitfalls. 16 patients with AIP (11 pts with resection) Compared with 16 PDA cases and 19 NOS CP 3 false positive diagnosis Stromal fragments with embedded lymphocytes (greater than 30 per 60x) were seen in 37.5% of AIP cases and only rarely with adenocarcinoma (12.5%) and pancreatitis, NOS (0%). - The cellularity of stromal fragments was significantly higher in AIP than in the control group Deshpande V - Am J Surg Pathol - 01-NOV-2005; 29(11):
30 Is autoimmune pancreatitis a systemic disease? Involves lung, biliary system, renal tubules, gall bladder and salivary glands Kamisawa. Am J Gastroenterology 2003 Deshpande V at al. Arch Pathol Lab Med Sep;129(9):
31 Summary Autoimmune pancreatitis is a distinct clinicopathological entity Easily confused with pancreatic carcinoma Serological markers including serum IgG4 may be very helpful The histological pattern in the pancreatic biopsy and IgG4 stain may contribute to the diagnosis Since most cases respond to steroids, an unnecessary pancreatic resection can be avoided
32 Questions? Is AP more common than previously thought and whether more cases will be diagnosed through increased clinical awareness? Does AP represents a systemic disease as apposed to a primary disease? Natural history of the disease after treatment or without treatment, needs to be better understood
Autoimmune Pancreatitis: A Great Imitator
Massachusetts General Hospital Harvard Medical School Autoimmune Pancreatitis: A Great Imitator Dushyant V Sahani MD dsahani@partners.org Autoimmune Pancreatitis: Learning Objectives Clinical manifestations
More informationChronic Pancreatitis
Falk Symposium 161 October 12, 2007 Chronic Pancreatitis David C Whitcomb MD PhD Giant Eagle Foundation Professor of Cancer Genetics. Professor of Medicine, Cell biology & Physiology, and Human Genetics
More informationIgG4-related sclerosing disease
IgG4-related sclerosing disease TERUMI KAMISAWA, KENSUKE TAKUMA, NAOTO EGAWA Department of Internal Medicine Tokyo Metropolitan Komagome Hospital 3-18-22 Honkomagome, Bunkyo-ku, Tokyo 113-8677, Japan JAPAN
More informationCHRONIC PANCREATITIS OR DUCTAL ADENOCARCINOMA? N. Volkan Adsay, \ MD
CHRONIC PANCREATITIS OR DUCTAL ADENOCARCINOMA? N. Volkan Adsay, \ MD Case for discussion 67 y/o male Back pain and weight loss CT: 4.5 cm ill-defined, solid lesion in the head FNA/Core bx: Inconclusive
More informationIgG4-Negative Autoimmune Pancreatitis with Sclerosing Cholangitis and Colitis: Possible Association with Primary Sclerosing Cholangitis?
CASE REPORT IgG4-Negative Autoimmune Pancreatitis with Sclerosing Cholangitis and Colitis: Possible Association with Primary Sclerosing Cholangitis? Keita Saeki 1, Shigenari Hozawa 1, Naoteru Miyata 1,
More informationLong-term Outcome of Autoimmune Pancreatitis after Oral Prednisolone Therapy
ORIGINAL ARTICLE Long-term Outcome of Autoimmune Pancreatitis after Oral Prednisolone Therapy Takayoshi Nishino 1, Fumitake Toki 2,HiroyasuOyama 3, Kyoko Shimizu 1 and Keiko Shiratori 1 Abstract Objective
More informationOverview of Diagnostic Criteria for Autoimmune Pancreatitis
2007 년도대한췌담도학회추계학술대회 Session II: Comparison of Diagnostic Criteria for AIP: Japan, USA & Korea Overview of Diagnostic Criteria for Autoimmune Pancreatitis Department of Internal Medicine, Seoul National
More informationValue of Serum IgG4 in the Diagnosis of Autoimmune Pancreatitis and in Distinguishing it from Acute and Chronic Pancreatitis of Other Etiology
94 Jul 2017 Vol 10 No.3 North American Journal of Medicine and Science Original Research Value of Serum IgG4 in the Diagnosis of Autoimmune Pancreatitis and in Distinguishing it from Acute and Chronic
More informationDiagnostic Algorithm for Autoimmune Pancreatitis in Korea
Review Article The Korean Journal of Pancreas and Biliary Tract 2014;19(1):7-12 pissn 1976-3573 eissn 2288-0941 한국에서자가면역췌장염의진단전략 성균관대학교의과대학삼성서울병원내과학교실 이종균 Diagnostic Algorithm for Autoimmune Pancreatitis
More informationAutoimmune pancreatitis (AIP) can be defined as a
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY 2006;4:1010 1016 Diagnosis of Autoimmune Pancreatitis: The Mayo Clinic Experience SURESH T. CHARI,* THOMAS C. SMYRK, MICHAEL J. LEVY,* MARK D. TOPAZIAN,* NAOKI
More informationAN UNUSUAL CASE OF OBSTRUCTIVE JAUNDICE- SURGICAL DILEMMA. Dr. Tejaswi Sindhiya Ragni
AN UNUSUAL CASE OF OBSTRUCTIVE JAUNDICE- SURGICAL DILEMMA Dr. Tejaswi Sindhiya Ragni A 65 year old male from Bangalore, farmer Presented with: Fever - 1 month Yellow discolouration of eyes and urine- 1month
More informationThe most common presentation of autoimmune pancreatitis. A Diagnostic Strategy to Distinguish Autoimmune Pancreatitis From Pancreatic Cancer
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY 2009;7:1097 1103 A Diagnostic Strategy to Distinguish Autoimmune Pancreatitis From Pancreatic Cancer SURESH T. CHARI,* NAOKI TAKAHASHI, MICHAEL J. LEVY,* THOMAS
More informationCASE REPORT. Abstract. Introduction. Case Report
CASE REPORT Branch Duct Intraductal Papillary Mucinous Neoplasms of the Pancreas Involving Type 1 Localized Autoimmune Pancreatitis with Normal Serum IgG4 Levels Successfully Diagnosed by Endoscopic Ultrasound-guided
More informationIgG4 Disease. General Principles of IgG4-related disease. EL Cluvar, AC Bateman
IgG4 Disease General Principles of IgG4-related disease. EL Cluvar, AC Bateman Diagnostic Guidelines for IgG4-related disease with a focus on histopathological criteria. V Deshpande, A Khosroshahi Diagnostic
More informationNoncalculous Biliary Disease Dean Abramson, M.D. Gastroenterologists, P.C. Cedar Rapids. Cholestasis
Noncalculous Biliary Disease Dean Abramson, M.D. Gastroenterologists, P.C. Cedar Rapids Cholestasis Biochemical hallmark Impaired bile flow from liver to small intestine Alkaline phosphatase is primary
More informationImmunoglobulin G4-Related Disease with Several Inflammatory Foci
CASE REPORT Immunoglobulin G4-Related Disease with Several Inflammatory Foci Akira Sakamaki 1, Kenya Kamimura 1, Kazuhiko Shioji 1, Junko Sakurada 2, Takeshi Nakatsue 3, Yoko Wada 3, Michitaka Imai 1,
More informationPancreatic Cancer Masquerading as Pancreatitis
Pancreatic Cancer Masquerading as Pancreatitis Poster No.: C-2553 Congress: ECR 2015 Type: Educational Exhibit Authors: A. Cahalane, Y. M. Purcell, L. Lavelle, E. R. Ryan, S. Skehan ; 1 1 2 2 2 2 2 Dublin,
More informationCase Scenario 1. Discharge Summary
Case Scenario 1 Discharge Summary A 69-year-old woman was on vacation and noted that she was becoming jaundiced. Two months prior to leaving on that trip, she had had a workup that included an abdominal
More informationMultiple Primary Quiz
Multiple Primary Quiz Case 1 A 72 year old man was found to have a 12 mm solid lesion in the pancreatic tail by computed tomography carried out during a routine follow up study of this patient with adult
More informationAutoimmune Pancreatitis: A Succinct Overview
REVIEW ARTICLE Autoimmune Pancreatitis: A Succinct Overview Juan Putra, Xiaoying Liu Department of Pathology, Dartmouth-Hitchcock Medical Center, One Medical Center Drive Lebanon, NH 03756, USA ABSTRACT
More informationCLASSIFICATION OF CHRONIC PANCREATITIS
CLASSIFICATION OF CHRONIC PANCREATITIS EAGE, Podstgraduate Course, Prague, April 2010. Tomica Milosavljević School of Medicine, University of Belgrade Clinical Center of Serbia,Belgrade The phrase chronic
More informationOverview of PSC Making the Diagnosis
Overview of PSC Making the Diagnosis Tamar Taddei, MD Assistant Professor of Medicine Yale University School of Medicine Overview Definition Epidemiology Diagnosis Modes of presentation Associated diseases
More informationIgG4 ᛶ ᝈ䛸 ᶫᮏ ᕫච ᛶ ⅖ ḷᒣ Ꮫ య Ꮫ ぬ㐨
IgG4 Autoimmune pancreatitis Histopathological features: Diffuse lymphoplasmacytic infiltration Stromal fibrosis Acinar atrophy Obliterative phlebitis 1. Hamano et al reported that serum IgG4 levels were
More informationUse of Samples From Endoscopic Ultrasound Guided 19-Gauge Fine- Needle Aspiration in Diagnosis of Autoimmune Pancreatitis
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY 2012;10:316 322 Use of Samples From Endoscopic Ultrasound Guided 19-Gauge Fine- Needle Aspiration in Diagnosis of Autoimmune Pancreatitis TAKUJI IWASHITA,* ICHIRO
More informationFrank Burton Memorial Update on Pancreato-biliary Cancers
Frank Burton Memorial Update on Pancreato-biliary Cancers Diagnosis and management of pancreatic cancer: common dilemmas Moderators: Banke Agarwal, MD Paul Buse, MD Evaluation of patients with obstructive
More informationType 2 Autoimmune Pancreatitis with Crohn s Disease
doi: 10.2169/internalmedicine.0213-17 Intern Med 57: 2957-2962, 2018 http://internmed.jp CASE REPORT Type 2 Autoimmune Pancreatitis with Crohn s Disease Yoon Suk Lee, Nam-Hoon Kim, Jun Hyuk Son, Jung Wook
More informationAnatomy of the biliary tract
Harvard-MIT Division of Health Sciences and Technology HST.121: Gastroenterology, Fall 2005 Instructors: Dr. Jonathan Glickman Anatomy of the biliary tract Figure removed due to copyright reasons. Biliary
More informationAutoimmune Pancreatitis and Retroperitoneal Fibrosis
Autoimmune Pancreatitis and Retroperitoneal Fibrosis Thomas C. Smyrk, MD Associate Professor of Pathology Mayo Clinic, Rochester MN 55902 smyrk.thomas@mayo.edu Summary Retroperitoneal fibrosis complicated
More informationAutoimmune Pancreatitis, Pancreatic and Extrapancreatic Imaging Findings
Autoimmune Pancreatitis, Pancreatic and Extrapancreatic Imaging Findings Poster No.: R-0074 Congress: RANZCR-AOCR 2012 Type: Educational Exhibit Authors: J. Stegeman, A. Borsaru; Clayton/AU Keywords: Education
More informationReview Article The Utility of Serum IgG4 Concentrations as a Biomarker
International Rheumatology Volume 2012, Article ID 198314, 4 pages doi:10.1155/2012/198314 Review Article The Utility of Serum IgG4 Concentrations as a Biomarker Shigeyuki Kawa, 1 Tetsuya Ito, 2 Takayuki
More informationAutoimmune pancreatitis (AIP) was described more than a
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY 2007;5:1229 1234 The Use of Immunoglobulin G4 Immunostaining in Diagnosing Pancreatic and Extrapancreatic Involvement in Autoimmune Pancreatitis MAESHA G. DEHERAGODA,*
More informationCase Report IgG4-Seronegative Autoimmune Pancreatitis and Sclerosing Cholangitis
Case Reports in Gastrointestinal Medicine Volume 2015, Article ID 591360, 6 pages http://dx.doi.org/10.1155/2015/591360 Case Report IgG4-Seronegative Autoimmune Pancreatitis and Sclerosing Cholangitis
More informationAutoimmune pancreatitis
Review Article Autoimmune pancreatitis Ayodeji Oluwarotimi Omiyale Department of Cellular Pathology, Maidstone Hospital, Maidstone, Kent, UK Correspondence to: Ayodeji Oluwarotimi Omiyale. Department of
More informationAutoimmune Pancreatitis & Cholangiopathy. Goal and Objectives
Autoimmune Pancreatitis & Cholangiopathy Kaveh Sharzehi, MD, MS Assistant Professor of Medicine Medical Director of Endoscopy Section of Gastroenterology Lewis Katz School of Medicine at Temple University
More informationChronic Pancreatitis: When to Scope? Gregory A. Cote, MD, MS Assistant Professor of Medicine Indiana University School of Medicine
Chronic Pancreatitis: When to Scope? Gregory A. Cote, MD, MS Assistant Professor of Medicine Indiana University School of Medicine Endoscopy & Chronic Pancreatitis Diagnosis EUS ERCP Exocrine Function
More informationPersonal Profile. Name: 劉 XX Gender: Female Age: 53-y/o Past history. Hepatitis B carrier
Personal Profile Name: 劉 XX Gender: Female Age: 53-y/o Past history Hepatitis B carrier Chief complaint Fever on and off for 2 days Present illness 94.10.14 Sudden onset of epigastric pain 94.10.15 Fever
More informationPrimary Sclerosing Cholangitis and Cholestatic liver diseases. Ahsan M Bhatti MD, FACP Bhatti Gastroenterology Consultants
Primary Sclerosing Cholangitis and Cholestatic liver diseases Ahsan M Bhatti MD, FACP Bhatti Gastroenterology Consultants I have nothing to disclose Educational Objectives What is PSC? Understand the cholestatic
More informationDiseases of pancreas - Chronic pancreatitis
Corso di laurea in Medicina e Chirurgia Anno accademico 2015-2016 V Anno di corso- Primo Semestre Corso Integrato : Patologia Sistemica C- Gastroenterologia Prof. Stefano Fiorucci Diseases of pancreas
More information3/28/2012. Periampullary Tumors. Postgraduate Course in General Surgery CASE 1: CASE 1: Overview. Eric K. Nakakura Ko Olina, HI
Overview Postgraduate Course in General Surgery Case presentation Differential diagnosis Diagnosis and therapy Outcomes Principles of palliative care Eric K. Nakakura Ko Olina, HI March 27, 2012 CASE 1:
More informationRenal manifestations of IgG4-related systemic disease
Renal manifestations of IgG4-related systemic disease Lynn D. Cornell, M.D. Mayo Clinic Rochester, MN While autoimmune pancreatitis (AIP) has been recognized since the first description by Sarles et al
More informationAutoimmune Liver Diseases
2nd Pannonia Congress of pathology Hepato-biliary pathology Autoimmune Liver Diseases Vera Ferlan Marolt Institute of pathology, Medical faculty, University of Ljubljana Slovenia Siofok, Hungary, May 2012
More informationHistological diagnosis of autoimmune pancreatitis using EUSguided trucut biopsy: a comparison study with EUS-FNA
J Gastroenterol (2009) 44:742 750 DOI 10.1007/s00535-009-0062-6 ORIGINAL ARTICLE LIVER, PANCREAS, AND BILIARY TRACT Histological of autoimmune pancreatitis using EUSguided trucut biopsy: a comparison study
More informationHow 5 Diseases Became One. Moez Tajdin R3 McGill University
How 5 Diseases Became One Moez Tajdin R3 McGill University Conflicts of Interest None! Mr. M. ID: 65 M PMH Benign prostatic hyperplasia Prostate cancer Awaiting biopsy Skin rash Dyslipidemia Hypertension
More informationThe Pancreas. Basic Anatomy. Endocrine pancreas. Exocrine pancreas. Pancreas vasculature. Islets of Langerhans. Acinar cells Ductal System
SGNA: Back to Basics Rogelio G. Silva, MD Assistant Clinical Professor of Medicine University of Illinois at Chicago Department of Medicine Division of Gastroenterology Advocate Christ Medical Center GI
More informationIgG4-related Sclerosing Disease: Autoimmune Pancreatitis and Extrapancreatic
Note: This copy is for your personal non-commercial use only. To order presentation-ready copies for distribution to your colleagues or clients, contact us at www.rsna.org/rsnarights. GASTROINTESTINAL
More information21/07/2017. CS Verbeke. Non-neoplastic disease of the pancreas PATHOLOGY OF NON-NEOPLASTIC PANCREATIC DISEASES
Non-neoplastic disease of the pancreas No indication for surgical resection of non-neoplastic disease (except end-stage chronic pancreatitis) Unexpected benign disease in 5-13% of pancreatic resections
More informationRenal Pathology Case Conference. Case 2
Renal Pathology Case Conference Case 2 Lynn D. Cornell, M.D. Mayo Clinic, Rochester, MN cornell.lynn@mayo.edu March 2, 2008 Clinical presentation 68 year old woman, initially with normal renal function
More informationComparison of multidetector-row computed tomography findings of IgG4-related sclerosing cholangitis and cholangiocarcinoma
Comparison of multidetector-row computed tomography findings of IgG4-related sclerosing cholangitis and cholangiocarcinoma Poster No.: C-0245 Congress: ECR 2014 Type: Scientific Exhibit Authors: M. Yata,
More informationD DAVID PUBLISHING. Groove Pancreatitis: A Case Report. 1. Introduction. 2. Case Report
Journal of Pharmacy and Pharmacology 6 (2018) 415-419 doi: 10.17265/2328-2150/2018.04.013 D DAVID PUBLISHING Luciana Leony Valente, Mariama Alves Dantas Fagundes, Camila Medrado Pereira Barbosa, Hélio
More informationEndoscopic Ultrasonography Findings in Autoimmune Pancreatitis: Be Aware of the Ambiguous Features and Look for the Pivotal Ones
MULTIMEDIA ARTICLE - Clinical Imaging Endoscopic Ultrasonography Findings in Autoimmune Pancreatitis: Be Aware of the Ambiguous Features and Look for the Pivotal Ones Stefania De Lisi 1, Elisabetta Buscarini
More informationFat, ballooning, plasma cells and a +ANA. Yikes! USCAP 2016 Evening Specialty Conference Cynthia Guy
Fat, ballooning, plasma cells and a +ANA. Yikes! USCAP 2016 Evening Specialty Conference Cynthia Guy Goals Share an interesting case Important because it highlights a common problem that we re likely to
More informationBiliary tract diseases of the liver
Biliary tract diseases of the liver Digestive Diseases Course Bucharest 2016 Rob Goldin r.goldin@imperial.ac.uk How important are biliary tract diseases? Hepatology 2011 53(5):1608-17 Approximately 16%
More informationImaging Guided Biopsy. Edited & Presented by ; Hussien A.B ALI DINAR. Msc Lecturer,Reporting Sonographer
Imaging Guided Biopsy Edited & Presented by ; Hussien A.B ALI DINAR. Msc Lecturer,Reporting Sonographer Objective By the End of this lessons you should : Define what biopsy Justify Aim to perform biopsy
More informationKey Points: Autoimmune Liver Disease: Update for Pathologists from the Hepatologist s Perspective. Jenny Heathcote, MD. University of Toronto
Autoimmune Liver Disease: Update for Pathologists from the Hepatologist s Perspective Jenny Heathcote, MD University of Toronto Key Points: AILD comprise autoimmune hepatitis, primary biliary cirrhosis
More informationAn Autopsy Case of Autoimmune Pancreatitis
MULTIMEDIA ARTICLE - Clinical Imaging An Autopsy Case of Autoimmune Pancreatitis Yohei Kitano 1, Kakuya Matsumoto 1, Kenji Chisaka 1, Masako Imazawa 1, Kenji Takahashi 1, Yukiomi Nakade 1, Mituyoshi Okada
More informationChronic pancreatitis mimicking intraductal papillary mucinous neoplasm of the pancreas; Report of tow cases
Jichi Medical University Journal Chronic pancreatitis mimicking intraductal papillary mucinous neoplasm of the pancreas; Report of tow cases Noritoshi Mizuta, Hiroshi Noda, Nao Kakizawa, Nobuyuki Toyama,
More informationChronic Pancreatitis
Gastro Foundation Fellows Weekend 2017 Chronic Pancreatitis Jose Ramos University of the Witwatersrand Donald Gordon Medical Centre Aetiology in SA Alcohol (up to 80%) Idiopathic Tropical Obstruction Autoimmune
More informationLIVER SPECIALTY CONFERENCE USCAP Maha Guindi, M.D. Clinical Professor of Pathology Cedars-Sinai Medical Center Los Angeles, CA
LIVER SPECIALTY CONFERENCE USCAP 2016 Maha Guindi, M.D. Clinical Professor of Pathology Cedars-Sinai Medical Center Los Angeles, CA Nothing to disclose Case History 47-year-old male, long standing ileal
More informationPancreas Quizzes c. Both A and B a. Directly into the blood stream (not using ducts)
Pancreas Quizzes Quiz 1 1. The pancreas produces hormones. Which type of hormone producing organ is the pancreas? a. Endocrine b. Exocrine c. Both A and B d. Neither A or B 2. Endocrine indicates hormones
More informationTratamiento endoscópico de la CEP. En quien como y cuando?
Tratamiento endoscópico de la CEP. En quien como y cuando? Andrés Cárdenas, MD, MMSc, PhD, AGAF, FAASLD GI / Liver Unit, Hospital Clinic Institut de Malalties Digestives i Metaboliques University of Barcelona
More informationCase Report An IgG4-Related Salivary Gland Disorder: A Case Series Presenting with a Different Clinical Setting
Case Reports in Immunology Volume 2011, Article ID 236079, 4 pages doi:10.1155/2011/236079 Case Report An IgG4-Related Salivary Gland Disorder: A Case Series Presenting with a Different Clinical Setting
More informationPAAF vs Core Biopsy en Lesiones Mamarias Case #1
5/19/2014 PAAF vs Core Biopsy en Lesiones Mamarias Case #1 Fine Needle Aspiration Cytology of Breast: Correlation with Needle Core Biopsy 64-year-old woman Mass in breast Syed Hoda, MD CD31 Post-Radiation
More informationNavigating the Biliary Tract with CT & MR: An Imaging Approach to Bile Duct Obstruction
Navigating the Biliary Tract with CT & MR: An Imaging Approach to Bile Duct Obstruction Ann S. Fulcher, MD Medical College of Virginia Virginia Commonwealth University Richmond, Virginia Objectives To
More informationWhat Is Pancreatitis?
What Is Pancreatitis? Pancreatitis is inflammation (swelling) of the pancreas that is most often caused by gallstones or alcohol abuse. There are other causes that your gastroenterologist will look for,
More informationTitle: Painless jaundice as an initial presentation of lung adenocarcinoma
Title: Painless jaundice as an initial presentation of lung adenocarcinoma Authors: Irene Andaluz García, Irene González Partida, Javier Lucas Ramos, Jorge Yebra Carmona DOI: 10.17235/reed.2018.5587/2018
More informationEvaluation and Management of Refractory Biliary Stricture. J. David Horwhat, MD, FACG Director of Endoscopy Lancaster Gastroenterology, Inc.
Evaluation and Management of Refractory Biliary Stricture J. David Horwhat, MD, FACG Director of Endoscopy Lancaster Gastroenterology, Inc Outline What defines a refractory biliary stricture Endoscopic
More informationResident, PGY1 David Geffen School of Medicine at UCLA. Los Angeles Society of Pathology Resident and Fellow Symposium 2013
Resident, PGY1 David Geffen School of Medicine at UCLA Los Angeles Society of Pathology Resident and Fellow Symposium 2013 85 year old female with past medical history including paroxysmal atrial fibrillation,
More informationWhat to do and not do before seeking surgical consultation for a patient with suspected pancreatic cancer
What to do and not do before seeking surgical consultation for a patient with suspected pancreatic cancer 9 Th Annual Symposium on Gastrointestinal Cancers, St. Louis University School of Medicine Carlos
More informationAutoimmune pancreatitis (AIP) is a chronic fibroinflammatory
Review Article Autoimmune Pancreatitis More Than Just a Pancreatic Disease? A Contemporary Review of Its Pathology Vikram Deshpande, MD; Mari Mino-Kenudson, MD; William Brugge, MD; Gregory Y. Lauwers,
More informationBiliary tree dilation - and now what?
Biliary tree dilation - and now what? Poster No.: C-1767 Congress: ECR 2012 Type: Educational Exhibit Authors: I. Ferreira, A. B. Ramos, S. Magalhães, M. Certo; Porto/PT Keywords: Pathology, Diagnostic
More informationIgG4-related hypophysitis presenting as a pituitary adenoma with systemic disease
Asian Journal of Surgery (2013) 36, 93e97 Available online at www.sciencedirect.com journal homepage: www.e-asianjournalsurgery.com CASE REPORT IgG4-related hypophysitis presenting as a pituitary adenoma
More informationEndoscopic Ultrasonography Assessment for Ampullary and Bile Duct Malignancy
Diagnostic and Therapeutic Endoscopy, Vol. 3, pp. 35-40 Reprints available directly from the publisher Photocopying permitted by license only (C) 1996 OPA (Overseas Publishers Association) Amsterdam B.V.
More informationDr Claire Smith, Consultant Radiologist St James University Hospital Leeds
Dr Claire Smith, Consultant Radiologist St James University Hospital Leeds Imaging in jaundice and 2ww pathway Image protocol Staging Limitations Pancreatic cancer 1.2.4 Refer people using a suspected
More informationIgG4-related Sclerosing Disease of the Lung without Pancreas Involvement: Presentation on 18F-FDG PET/CT
J Radiol Sci 2013; 38: 129-133 IgG4-related Sclerosing Disease of the Lung without Pancreas Involvement: Presentation on 18F-FDG PET/CT Han-Jui Lee 1 Yi-Chen Yeh 2,3 Chun-Ku Chen 1,3 Rheun-Chuan Lee 1,3
More informationEndoscopic Management of Biliary Strictures. Sammy Ho, MD Director of Pancreaticobiliary Services and Endoscopic Ultrasound Montefiore Medical Center
Endoscopic Management of Biliary Strictures Sammy Ho, MD Director of Pancreaticobiliary Services and Endoscopic Ultrasound Montefiore Medical Center Malignant Biliary Strictures Etiologies: Pancreatic
More informationENDOSCOPY IN COMPETITION DIAGNOSTICS. Dr. med. Dirk Hartmann Klinikum Ludwigshafen
Falk Symposium 166 GI Endoscopy Standards and Innovations Mainz, 18. 19. September 2008 ENDOSCOPY IN COMPETITION DIAGNOSTICS Dr. med. Dirk Hartmann Klinikum Ludwigshafen ENDOSCOPY IN COMPETITION Competing
More informationHistology. The pathology of the. bile ducts. pancreas. liver. The lecture in summary. Vt-2006
Vt-2006 The pathology of the liver, bile ducts and pancreas Richard Palmqvist Docent, ST-läkare, Klin Pat Lab, Labcentrum The lecture in summary Introduction, histology & physiology in brief General phenomenon
More informationU Nordic Forum - Trauma & Emergency Radiology. Lecture Objectives. MDCT in Acute Pancreatitis. Acute Pancreatitis: Etiologies
Nordic Forum - Trauma & Emergency Radiology Lecture Objectives MDCT in Acute Pancreatitis Borut Marincek Institute of Diagnostic Radiology niversity Hospital Zurich, Switzerland To describe the role of
More informationDifferentiating Immunoglobulin G4-Related Sclerosing Cholangitis from Hilar Cholangiocarcinoma
Gut and Liver, Vol. 7, No. 2, March 2013, pp. 234-238 ORiginal Article Differentiating Immunoglobulin G4-Related Sclerosing Cholangitis from Hilar Cholangiocarcinoma Taku Tabata*, Terumi Kamisawa*, Seiichi
More informationDiagnosis of chronic Pancreatitis. Christoph Beglinger, University Hospital Basel, Switzerland
Diagnosis of chronic Pancreatitis Christoph Beglinger, University Hospital Basel, Switzerland Pancreatitis Pancreas Pancreas - an organ that makes bicarbonate to neutralize gastric acid, enzymes to digest
More informationCommon and unusual CT and MRI manifestations of pancreatic adenocarcinoma: a pictorial review
Review Article Common and unusual CT and MRI manifestations of pancreatic adenocarcinoma: a pictorial review Min-Jie Yang, Su Li, Yong-Guang Liu, Na Jiao, Jing-Shan Gong Department of Radiology, Shenzhen
More informationAutoimmune pancreatitis: the classification puzzle
Advances in Medical Sciences Vol. 52 2007 Autoimmune pancreatitis: the classification puzzle 71 Autoimmune pancreatitis: the classification puzzle Fantini L, Zanini N, Fiscaletti M, Calculli L, Casadei
More informationGreater Manchester and Cheshire HPB Unit Guidelines for the Assessment & Management of Hepatobiliary and Pancreatic Disease Chapter 11
Greater Manchester and Cheshire HPB Unit Guidelines for the Assessment & Management of Hepatobiliary and Pancreatic Disease Chapter 11 Contents 11. Chronic Pancreatitis 138 11.1. Overview of management
More informationChronic Biliary Disease. Dr Susan Davies & Dr Bill Griffiths
Chronic Biliary Disease Dr Susan Davies & Dr Bill Griffiths Chronic Biliary Disease Terminology is confusing with pathologists and hepatologists using the same language BUT with different meanings. Chronic
More informationCase 1- B.N. 66 yr old F with PMHx of breast cancer s/ p mastectomy, HTN, DM presented with dysphagia to solids and liquids.
Case 1- B.N 66 yr old F with PMHx of breast cancer s/ p mastectomy, HTN, DM presented with dysphagia to solids and liquids. Reports retching to clear esophagus. Case 1- B.N EGD: Stricture in the distal
More informationIsolated Mass-Forming IgG4-Related Cholangitis as an Initial Clinical Presentation of Systemic IgG4-Related Disease
Journal of Pathology and Translational Medicine 2016; 50: 300-305 CASE STUDY Isolated Mass-Forming IgG4-Related Cholangitis as an Initial Clinical Presentation of Systemic IgG4-Related Disease Seokhwi
More informationUsual Interstitial pneumonia and Nonspecific Interstitial Pneumonia. Nitra and the Gangs.
Usual Interstitial pneumonia and Nonspecific Interstitial Pneumonia Nitra and the Gangs. บทน ำและบทท ๓, ๑๐, ๑๒, ๑๓, ๑๔, ๑๕, ๑๗ Usual Interstitial Pneumonia (UIP) Most common & basic pathologic pattern
More informationOutline 11/2/2017. Pancreatic EUS-FNA general aspects. Cytomorphologic features of solid neoplasms/lesions of the pancreas
ENDOSCOPIC ULTRASOUND GUIDED-FINE NEEDLE ASPIRATION CYTOLOGY OF PANCREAS Khalid Amin M.D. Assistant Professor Department of Laboratory Medicine and Pathology University of Minnesota Outline Pancreatic
More informationCase Report The Challenging Diagnosis of Pancreatic Masses: Not All Tumors Are Cancers
Case Reports in Medicine Volume 2015, Article ID 832463, 4 pages http://dx.doi.org/10.1155/2015/832463 Case Report The Challenging Diagnosis of Pancreatic Masses: Not All Tumors Are Cancers Alessandro
More informationCholangiocarcinoma (Bile Duct Cancer)
Cholangiocarcinoma (Bile Duct Cancer) The Bile Duct System (Biliary Tract) A network of bile ducts (tubes) connects the liver and the gallbladder to the small intestine. This network begins in the liver
More informationBenign, Reactive and Inflammatory Lesions of the Breast
Benign, Reactive and Inflammatory Lesions of the Breast Marilin Rosa, MD Associate Member Section Head of Breast Pathology Department of Anatomic Pathology Program Director, Breast Pathology Fellowship
More informationThe role of ERCP in chronic pancreatitis
The role of ERCP in chronic pancreatitis Marianna Arvanitakis Erasme University Hospital, ULB, Brussels, Belgium 10 th Nottingham Endoscopy Masterclass SPEAKER DECLARATIONS This presenter has the following
More informationColangitis Esclerosante Primaria: Manejo Clínico y Endoscópico
Colangitis Esclerosante Primaria: Manejo Clínico y Endoscópico Andrés Cárdenas, MD, MMSc, PhD, AGAF, FAASLD GI / Liver Unit, Hospital Clinic Institut de Malalties Digestives i Metaboliques Associate Professor
More information5/17/2013. Pancreatic Cancer. Postgraduate Course in General Surgery CASE 1: CASE 1: Overview. Case presentation. Differential diagnosis
Overview Case presentation Postgraduate Course in General Surgery Differential diagnosis Diagnosis and therapy Eric K. Nakakura Koloa, HI March 26, 2013 Outcomes CASE 1: CASE 1: A 78-year-old man developed
More informationProf. (DR.) MD. ISMAIL PATWARY. MBBS, FCPS, MD, FACP, FRCP(Glasgow, Edin) Professor, Dept. of Medicine, Sylhet women s Medical College, Sylhet
Prof. (DR.) MD. ISMAIL PATWARY MBBS, FCPS, MD, FACP, FRCP(Glasgow, Edin) Professor, Dept. of Medicine, Sylhet women s Medical College, Sylhet CHRONIC PANCREATITIS Defined as a progressive inflammatory
More informationAutoimmune pancreatitis (AIP), a clinical entity originally
Autoimmune Pancreatitis: A Multiorgan Disease Presenting a Conundrum for Clinicians in the West Eileen Kim, MD, Rebecca Voaklander, MD, Franklin E. Kasmin, MD, William H. Brown, MD, Rifat Mannan, MD, and
More informationBiliary cytolgy and pancreatic endoscopic ultrasound-guided FNA. Leena Krogerus Helsinki, FINLAND
Biliary cytolgy and pancreatic endoscopic ultrasound-guided FNA Leena Krogerus Helsinki, FINLAND Reasons for biliary cytology PSC- is a pre-neoplastc condition in youg individulas, the cure of which is
More informationIgG4 Related disease a retrospective descriptive study highlighting Canadian experiences in diagnosis and management
Patel et al. BMC Gastroenterology 2013, 13:168 RESEARCH ARTICLE Open Access IgG4 Related disease a retrospective descriptive study highlighting Canadian experiences in diagnosis and management Harshna
More informationUlcerative Colitis and Immunoglobulin G4
Gut and Liver, Vol. 8, No. 1, January 2014, pp. 29-4 ORiginal Article Ulcerative Colitis and Immunoglobulin G4 Go Kuwata*, Terumi Kamisawa*, Koichi Koizumi*, Taku Tabata*, Seiichi Hara*, Sawako Kuruma*,
More informationRole of Imaging Methods in Diagnosis of Acute Pancreatitis. Válek V. Radiologická klinika, FN Brno a LF MU v Brně
Role of Imaging Methods in Diagnosis of Acute Pancreatitis Válek V. Radiologická klinika, FN Brno a LF MU v Brně New Classification: Acute Pancreatitis 2007 revision of Atlanta classification and definitions
More information