CURRICULUM VITAE DR. ADINA MAZILU

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1 CURRICULUM VITAE DR. ADINA MAZILU POZITIE ACTUALA: medic primar Endocrinologie din prezent medic specialist Diabet zaharat, Nutritie si Boli metabolice din 2013-prezent angajata a S.U.U.M.C Dr. Carol Davila Sectia Endocrinologie competenta in Ecografia glandelor endocrine si Sexologie diploma de Certified Clinical Densitometrist experienta in DXA-operare si interpretare DXA din 2008 responsabil cu Nutritia in cadrul SUUMC Dr. Carol Davila responsabil de Management infectii nosocomiale in cadrul Sectiei Endocrinologie a SUUMC Dr. Carol Davila curs de Prim ajutor medical specializat 2000 si curs de Radioprotectie 2016 COMPETENTE PERSONALE: LB. ENGLEZA- NIVEL C1 LB. FRANCEZA- NIVEL C1 PARTICIPARE LA EMISIUNI TELEVIZATE-FRESH REFRESH-REALITATEA TV-2016, B1 TV, TVR 1, Kanal D STUDII CLINICE MULTICENTRICE - SUBINVESTIGATOR A long-term study of sibutramine and the role of obesity management in relation to cardiovascular disease in overweight and obses patients (SCOUT), trial de faza III, Sponsor- Abbott, directorul studiului Cheryl Renz, MD ROADMAP, (Randomized Olmesartan an Diabetes microalbuminuria Prevention Study)trial de faza III. n caltr als.gov/show/nct Sponsor Sankyo Pharma Gmbh PLANET 1 (D3569C00007)- Randomised, Double-blind, 52-wk, Parallelgrp, Multicentre, PIIb Study to Evaluate Effects of Rosuvastatin 10mg, Rosuvastatin 40mg and Atorvastatin 80mg on Urinary Protein Excretion in Hypercholesterolaemic Diabetic Patients With Moderate Proteinuria,trial faza II, Sponsor Astra Zeneca Protocol 306A1-300-EUA Multicenter, Double Blind, Randomized, Placebo and Raloxifene Controlled Study to Assess Safety and Efficacy of TSE-424 (Bazedoxifene Acetate) in the Prevention of Postmenopausal Osteoporosis, trial de faza III, Wyeth Research Protocol 3047K5-319-WWA Multicenter, Randomized, Double-Blind, Comparison Study of the Safety and Efficacy of a Once-Daily Dose of Tigecycline Versus Ertapenem for the Treatment of Foot Infections in Subjects With Diabetes. n caltr als.gov/ct2/show/studv/nct Wyeth Research International, Multi-center Post Authorization Surveillance Study on the Use of Nebido to Assess Tolerability and Treatment Outcomes in Daily Clinical Practice (IPASS Nebido), trial de fazaiii. n caltr als.gov/ct2/show/nct Sponsor Bayer Protocol 3068A1-301-WW: Fracture Incidence Reduction And Safety Of TSE-424 (Bazedoxifene Acetate) Compared To Placebo And Raloxifene In Osteoporotic Postmenopausal Women, trial de faza III, Wyeth Research ,A Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Study to Evaluate Cardiovascular Outcomes During Treatment With Lixisenatide in Type 2 Diabetic Patients After an Acute Coronary Syndrome (ELIXA)- studiuclinic multinational, multicentric de faza III, sindroame coronare acute, , sponsor Sanofi-Aventis

2 A Phase IIIB study to evaluate the potential of Aleglitazar to reduce cardiovascular risk in patients with stable cardiovascular disease and glucose abnormalities; ; trial de faza IIIB; Sponsor Hoffman-LaRoche A Multicenter, Randomized, Double-Blind, Active Controlled, Parallel Group, Phase 3 Trial to Evaluate the Safety and Efficacy of Add-On Therapy With Saxagliptin and Dapagliflozin Added to Metformin Compared to Add-On Therapy With Saxagliptin in Combination With Metformin or Dapagliflozin in Combination With Metformin in Subjects With Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin Alone; MB Study; trial de faza III; Sponsor Bristol-Myers Squibb 2012-prezent A Multicenter, Randomized, Double-Blind, Placebo Controlled, Parallel Group, Phase 3 Trial to Evaluate the Safety and Efficacy of Triple Therapy With Saxagliptin Added to Dapagliflozin in Combination With Metformin Compared to Therapy With Placebo Added to Dapagliflozin in Combination With Metformin in Subjects With Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin and Dapagliflozin; stdiu de faza III multicentric, multinational: ; Sponsor Bristo- Myers Squibb Company 2012-prezent A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Phase 3 Trial to Evaluate the Safety and Efficacy of Therapy With Dapagliflozin Added to Saxagliptin in Combination With Metformin Compared to Therapy With Placebo Added to Saxagliptin in Combination With Metformin in Subjects With Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin and Saxagliptin; studiu clinic de faza III multicentric, multinational; ; Sponsor Bristol-Myers Squibb Company A Phase IIIB study to evaluate the potential of Aleglitazar to reduce cardiovascular risk in patients with stable cardiovascular disease and glucose abnormalities; ; trial de faza IIIB; Sponsor HoffmanLaRoche 2013-prezent Phase 3 Multi Center, Double Blind, Randomized, Placebo Controlled, Parallel Group Evaluation Of The Efficacy, Safety, And Tolerability Of PF , In Reducing The Occurrence Of Major Cardiovascular Events In High Risk Subjects; studiu clinic de faza III; ; Sponsor Pfizer A Randomised, Double Blind, Placebo Controlled, Parallel Group, Dose Ranging Study of GWP42004 as Add on to Metformin in the Treatment of Participants With Type 2 Diabetes; ; Sponsor GW Pharmaceuticals 2013-prezent A Phase 3 Double-Blind, Randomized, Placebo-Controlled, Parallel- Group Study To Assess The Efficacy, Safety And Tolerability Of Pf In Subjects With Primary Hyperlipidemia Or Mixed Dyslipidemia At Risk Of Cardiovascular Events; ; sponsor Pfizer prezent A Randomized, 30 Week, Active-controlled, Open-label, 3-treatment Arm, Parallelgroup Multicenter Study Comparing the Efficacy and Safety of Insulin Glargine/ Lixisenatide Fixed Ratio Combination to Insulin Glargine Alone and to LixisenatideAlone on Top of Metformin in Patients With Type 2 Diabetes Mellitus T2DM; ; sponsor Sanofi Aventis 2014-prezent A Randomized, Double-blind, Event-driven, Placebo-controlled, Multicenter Study of the Effects of Canagliflozin on Renal and Cardiovascular Outcomes in Subjects With Type 2 Diabetes Mellitus and Diabetic Nephropathy, ; sponsor Janssen research and Developpment, LLC 2015-prezent A multicenter, randomized, double-blind, placebo-controlled, parallel group, phase 3 trial to evaluate the safety and efficacy of once weekly Exenatide

3 therapy added to titrated Basal Insulin Glargine compared to placebo added to titrated Basal Insulin Glargine in patients with type 2 diabetes who have inadequate glycemic control on Basal Insulin Glargine with or without Metformin; sponsor Astra Zeneca 2015-prezent A 28-week, Multicenter, Randomized, Double-Blind, Active- Controlled, Phase 3 Study With a 24-week Extension Phase Followed by a 52-week Extension Phase to Evaluate the Efficacy and Safety of Simultaneous Administration of Exenatide Once Weekly 2 mg and Dapagliflozin Once Daily 10 mg Compared to Exenatide Once Weekly 2 mg Alone and Dapagliflozin Once Daily 10 mg Alone in Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin; ; sponsor Astra Zeneca CURSURI DE PERFECTIONARE Cursurile Postuniversitare ETA (European Thyroid Association),Poiana Brasov, Al XV lea Congres National de Endocrinologie,Asociatia Romana de Endoccrinologie, European Thyroid Association GCP Training Complinace, Bucharest, Romania Cursuri de 12 saptamani pentru Competenta de Sexologie Curs de radioprotectie Nivel 2 PREZENTARI LA MANIFESTARI STIINTIFICE INTERNE: Simpozion Terapii inovatoare in osteoporoza- primii doi ani de experienta si concluzii; Congresul Nationala de Endocrinologie cu Participare Internationala, ed XXI, Reductil presentations- Abbott Prezentari pentru compania Abbott, Amgen, MSD LUCRARI STIINTIFICE CONGRESE: 1. Micro- si macroprolactinoamele sunt două boli distincte? Diagnostic - Congresul European de Endocrinologie - Torino, Italia, 9-13 iunie Consequences of belated treatment in primary mixedema- AE Ranetti, N Diaconu, C Spiroiu, C Dumitrache, S Blaj, V Mihalache, M Flueras, A Onofrei;poster presentation, 5th European Congress of Endocrinology, , Turin Italy, rezumat publicat in volumul de rezumate al congresului 3. Efectele Sibutiraminei asupra profilului lipidic; Dr A.E. Ranetii, Dr. Adina-Onofrei- Mazilu, Congresul National Obezitatea si bolile asociate, Cluj Hiperparatiroidismul secundar la femeile în postmenopauză - incidentă, aspecte clinice, implicatii terapeutice; Dr. A. Ranetti, dr. N.Diaconu, Dr. C.Spiroiu, dr. Ana- Maria Mihai, Dr. Adina Mazilu - CongresulNational de Endocrinologie - Craiova, 5-7iunie Tiroidita cronică autoimună asociată cu alte boli autoimune; Dr. A. Ranetti, dr. N.Diaconu, Dr. C.Spiroiu, dr. Ana-Maria Mihai, Dr. Adina Mazilu - Congresul National de Endocrinologie - Craiova, 5-7 iunie Consideratii terapuetice privind disfunctia erectila la pacientii diabetici- AE Ranetti, C Spiroiu, AM Mihai, N diaconu, A Mazilu; Al 29lea congres national de diabet, nutritie si boli metabolice cu particpare internationala, mai 2003, Craiova, rezumat publicat in Acta diabetologica Romana, vol XXIX Aspecte etiopatogenice si clinico-evolutive ale unor forme secundare de diabet zaharat; dr. A.E. Ranetti, dr. C.Spiroiu,dr. A.Mihai, dr. A.Mazilu; Al 29lea congres national de diabet, nutritie si boli metabolice cu particpare internationala, mai 2003, Craiova, rezumat publicat in Acta diabetologica Romana, vol XXIX Endocrinological features of atrial fibrillation; dr. A.E. Ranetti, dr.c.spiroiu,dr.a.mihai,dr.a.mazilu; 8th Congress of Balkan Military Medical Committee, 2124 sept 2003, Cluj Napoca, Romania, Rezumat publicat in volumul de rezumate al congresului

4 9. Clinical and pathological aspects of some secondary forms of diabetes mellitus; dr. A.E. Ranetti, dr. C.Spiroiu, dr. A.Mihai, dr.a.mazilu; 8th Congress of Balkan Military Medical Committee, sept 2003, Cluj Napoca, Romania, Rezumat publicat in volumul de rezumate al congresului 10. Feocromocitomul malign bilateral - prezentare atipică - ENEA -Sorrento, Italia, aprilie Tiroidita subacută si bicitopenia după terapia cu interferon 2-a administrat în hepatite - ENEA - Sorrento, Italia, aprilie Poliglandular autoimmune syndrome associated with meningioma; dr. A.E. Ranetti, dr. C.Spiroiu, A.Mihai, A.Mazilu;Congresul Balcanic de Medicină Militară, Istanbul, iunie Management of thyroid cancer in children - 5 years experience; dr. A.E. Ranetti, dr. C.Spiroiu, dr. A.Mihai, dr. A.Mazilu;Congresul Balcanic de Medicină Militară, Antalya, iunie Particularităti evolutive în carcinomul papilar tiroidian; dr.a.mazilu, dr.a.e.ranetti,r.mititelu,gmarinescu,prof.dr.codorean;congresul National de Endocrinologie,Timisoara, Modificări psihice la o serie de pacienţi cu boală Graves-Basedow -Congresul National de Neuroendocrinologie-Poiana Brasov, 3-6 iunie Sindromul depresiv în hiperprolactinemii - Congresul National de Neuroendocrinologie - Poiana Brasov, 3-6 iunie Dificultăţi de diagnostic în insulinoame - Congresul National de Neuroendocrinologie - Poiana Brasov, 3-6 iunie Pollyglandular autoimmune syndrome associated with meningioma.adina Mazilu,., Ana- Maria Mihai, Cristina Spiroiu., Lt-Col. A.E.Ranetti, 9th Congress of Balkan Military Medical Committee,21-24 June 2004, Antalya, TURKEY Abstract published in Balkan Military Medical Review 19. The efficacy of levothyroxine therapy in the nontoxic multinodular goiter,a.e.ranetti C Spiroiu, Am. Mihai, A. Mazilu, C. Ranetti Pharmacist, C.Stefan. D Mihai. 9th Congress ofbalkan Military Medical Committee,21-24 June 2004, Antalya, TURKEY 20. Follow-up of fibrocystic mastosis In postmenopausal women; Adina Mazilu, Ana- Maria Mihai, Cristina Spiroiu.,Lt-Col. A.E.Ranetti, 9th Congress ofbalkan Military Medical Committee,21-24 June 2004, Antalya, TURKEY, 21. Prevalence of the metabolic syndrome in overweight adults. Adina Mazilu,, Ana- Maria Mihai, Cristina Spiroiu, Lt-Col. A.E.Ranetti, M. Costin, 9th Congress of Balkan Military Medical Committee,21-24 June 2004, Antalya, TURKEY Abstract published in Balkan Military Medical Review 22. A rare form of secondary osteoporosis - osteogenesis imperfecta - Case Report - C. Spiroiu, A.E.Ranetti, N. Diaconu, A. Popescu, A. Mazilu, A.M. Mihai, Cpt. C. Ranetti, Pharm., 9th Congress ofbalkan Military Medical Committee,21-24 June 2004, Antalya, TURKEY; 23. Ulceration in diabetic foot - Dr. N. Diaconu. Dr. A.E.Ranetti. Dr. C. Spiroiu, Dr. Ana-Maria Mihai, Pharm. Cristina Ranetti, Dr. Adina Mazilu, 9th Congress of Balkan Military Medical Committee,21-24 June 2004, Antalya, TURKEY Abstract published in Balkan Military Medical Review 24. Consecinte ale patologiei endocrine in stomatologie, Congresul International de Stomatologie, 8-11 martie 2005, Bucuresti, Romania; A.E. Ranetti, C.Spiroiu, A. Mazilu,A.M. Mihai 25. Sibutiramine efficiency in metabolic control of obese diabetic patients- A Mazilu, A Mihai, C Spiroiu, AE Ranetti, oral presentation, 14th European Congress on Obesity Pregnancies in women with premature ovarian failure. A.E.Ranetti; A.M. Mihai; C.Spiroiu; A.Mazilu - The 13th Balkan Congress of Endocrinology, October 2005, Bucharest, Romania; Abstract published in Balkan Military Medical Review

5 27. Papillary thyroid carcinoma with invasion in the medullary canal T1 - T2 - A.E.Ranetti; A.M. Mihai; C.Spiroiu; A.Mazilu- The13th Balkan Congress of Endocrinology, October 2005, Bucharest, Romania; 28. The efficacy of levothyrooxine therapy in the nontoxic multinodular goiter- AM Mihai, AE Ranetti, C Spiroiu, A Mazilu,C Ranetti, poster presentation, 8th european Congress of Endcorinology incorporating the British Endocrine Societies, abstract published in 'Endocrine Abstracts, ISSN (print), ISSN (on-line), volume 11, april 2006, 1-5 april 2006, Glasgow, UK 29. Management of thyroid cancer in children- A Mazilu, AE Ranetti, A Mihai, C spiroiu, poster presentation, 8th european Congress of Endcorinology incorporating the British Endocrine Societies, abstract published in Endocrine Abstracts, ISSN (print), ISSN (on-line), volume 11, april 2006, 1-5 april 2006, Glasgow, UK 30. Diagnosis difficulties in insulinomas. AE Ranetti,A.Mazilu, C. Spiroiu & A.Mihai - 8th european Congress of Endocrinology incorporating the British Endocrine Societies, 1-5 April, 2006 Glasgow, UK; 31. Implicatiile cavitatii bucale in relatiile de cuplu. Ranetti A.E., Spiroiou C., Mazilu A., Mihai A.M. - A VI a Conferinta Nationala de Medicina Sexualitatii, martie 2006, Bucuresti, rezumat publicat in volumul de rezumate al congresului. 32. Obesity and sexual life in men, A.E. Ranetti, A. Mazilu, C. Spiroiu, AM. Mihai, International Congress on Obesity, 3-8 Sept. 2006, Sydney, Australia, 33. Paraneoplastic Cushing's syndrome presenting as psychosis - case report, Cristina Spiroiu, A.E. Ranetti, Ana Maria Mihai, Adina Mazilu, N. Diaconu, 9th European Congress of Endocrinology, 28-apr.-02 may 2007, Budapest, 34. Sexualitatea si menopauza. Ana Maria Mihai, A.E.Ranetti, Cristina Spiroiu, N. Diaconu, Adina Mazilu - Al XIV-lea Simpozion National de Psihoneuroendocrinologie, mai2007, Sibiu, 35. Sibutramine efficency in metabolic control of obese diabetic patients, A. Mazilu, A.Mihai, C. Spiroiu, A.E. Ranetti, 14th European Congress on Obesity, 1-4 June 2005, Athens, 36. Sindrom Cushing paraneoplazic cu debut psihotic. Spiroiu C., Ranetti A.E., Mazilu A., Mihai A.M.; 12th Congress of Balkan Military Medical Committee, June 24-28, 2007, Poiana Brasov, Romania; 37. Hipotiroidism cu debut psihotic mixedem madness - prezentare de caz. Spiroiu C., Ranetti A.E., Mazilu A., Mihai A.M., Vasile D., Tudor C., Vasiliu O.; 12th Congress of Balkan Military Medical Committee, June 24-28, 2007, Poiana Brasov, Romania 38. Effects of sibutramine and other therapies on erectile dysfunction in diabetic patients, A.E. Ranetti, C.Spiroiu, A. Mazilu, 16th European Congress on Obesity, may2008,geneva, 39. Mullerian anomalies in medical practice uterusdidelphys with cervix and double vagina on a patient with PCOS. Case presentation- T Raluca, S. Cristina, AE Ranetti, M. Enyedi, A. Mazilu; Al XI-lea Congres Al Societatii Anatomistilor din Romania, Constanta, poster 40. Detectia tumorilor carcinoide prin imagistica de fuziune PET-CT, A Mazilu, C Mazilu, G Ionescu, Al VXI lea simpozion National de Psihoneuroendocrinologie, mai 2010, Poiana Brasov 41. Ficatul gras non-alcoolic si microalbuminuria la pacientii cu diabet zaharat tip 2 ; C. Constantin, C. Spiroiu, A. Mazilu, G Constantin, N. Diaconu, A.E. Ranetti, Congresul national de endocrinologie 2012, Bucuresti, Palatul Parlamentului 42. Non-alcoholic fatty liver si microalbuminuria la pacientii cu diabet zaharat tip II- C.Constantin, C Spiroiu, A Mazilu, G Constantin, N Diaconu, V Cristescu, AE Ranetti, Simpozionului Zilele Spitalului Universitar de Urgenţă Militar Central Dr. Carol Davila octombrie 2012,Bucuresti; Rezumat publicat in Revista de Mediana Militara,2012, ISSN , indexata CNCSIS C 43. Hyperthyroidism refractory to antithyroid drugs- case report- A. Mazilu, AE Ranetti, prezentare poster PP114; 18th Congress of the Balkan Military Medical

6 Committee, 2012,May 29th - June 1st, Istanbul, Turkey. Rezumat publicat in Balkan Military Medical Review,2013, 16(3):238; e-issn ; 44. Terapii inovatoare in osteoporoza- A.Mazilu, C. Spiroiu, AM Munteanu, N. Diaconu, AE Ranetti; Prezentare orala la Prima Conferinţă de medicină militară şi cea de-a treia ediţie a Simpozionului Zilele Spitalului Universitar de Urgenţă Militar Central Dr. Carol Davila octombrie 2013,Bucuresti; Rezumat publicat in Revista de Medicina Militara 45. ECE Congress 2015-A challenging case of paraneoplastic Cushing's syndrome Adina Mazilu; Mona Gheorghiu; Madalina Musat; Aurelian-Emil Ranetti; Victor - Catalin Mazilu; Narcis Tanase; Razvan Petrescu; Published: ECE 2016-Munich -Malignant giant pituitary tumor- Adina Mazilu-EP Nutritional approach in late gastric stenosis after gastric sleeve, Adina Mazilu, M.D., Dept.of Endocrinology and Metabolism, Central Military Emergency Hospital,Revista de Medicina Militara