Acute Stroke with Alteplase Administration Order Set
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- Mae Burke
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1 Review Due Date: 2017 October PATIENT CARE DERS Weight: Adverse Reactions or Intolerances Drug No Yes (list) Food No Yes (list) _ Latex No Yes Admission Admit to Neurology service: Dr. Critical Care Diagnosis: Code Status: (Prescriber to complete Code Status/Advance Directives Orders) ***Start Collaborative Care Plan for Acute Ischemic Stroke*** Consults Diet Occupational Therapy Physiotherapy Social Work Registered Dietitian Speech Language Pathologist Diagnosis of brain stem stroke Dysphagia screen positive To assess communication Vascular Surgery (for patients with greater than 50% stenosis in the internal carotid artery) Diabetes Nurse Practitioner Endocrinologist NPO Dysphagia screen (Use Screening Tool for Acute Neurological Dysphagia-STAND) 24 hours after alteplase initiation (may give food and water for screen only) (Brain stem stroke is exclusion criteria and requires an Speech Language Pathology consult) Activity Bed rest for 24 hours following alteplase administration, then activity as tolerated (AAT) kg Page 1 of 6
2 PATIENT CARE DERS Vitals/Monitoring Vitals Temperature, HR, RR, BP, SpO2 q15 min for 2 hours THEN q1 h for 22 hours THEN q4 6 h for 48 hours THEN reassess Notify physician if systolic BP is greater than mmhg, or less than mmhg diastolic BP is greater than mmhg, or less than mmhg Angioedema monitoring at 30, 45, 60, and 75 minutes following alteplase initiation, then q4-6 h for 24 hours Neurovitals Canadian Neurological Scale (for alert or drowsy patients) Glasgow Coma Scale (for stuporous patients): q15 min for 2 hours THEN q1 hours for 22 hours THEN q4 6 h for 48 hours THEN reassess Monitoring Cardiac monitoring Continuous SpO 2 monitoring Intake and output q shift Lines/Respiratory Lines 2 IV lines (the primary IV should have a minimum gauge IV catheter of 18, preferably in the antecubital site) Respiratory Oxygen Therapy Protocol (Prescriber to complete Oxygen Therapy Protocol orders) Lab Investigations 12 lead ECG CBC, electrolytes, urea, creatinine, PT, PTT, INR, serum glucose, calcium, magnesium, albumin, ALP, ALT, total bilirubin, troponin, Beta HCG in females less than 50 years HbA1c Lipid profile (total cholesterol, cholesterol/hdl ratio, triglycerides, LDL cholesterol, HDL cholesterol) following 14 hour fast in morning Blood glucose by glucose meter stat: (If first random blood glucose is greater than 10mmol/L repeat blood glucose) For diabetic patients (prescriber to complete appropriate diabetic order sets) Capillary blood glucose qid and prn Type and Hold 2 units Red Cell Concentrate Page 2 of 6
3 PATIENT CARE DERS Diagnostic Imaging CT scan of head CT angiogram of head and neck CT perfusion scan MRI CXR Portable Carotid Doppler Studies 24 hour Holter monitor Echocardiogram Other: IV Fluids IV Fluid Primary IV: 0.9% sodium chloride (0.9% NaCl) at ml/h Secondary IV: IV 0.9% sodium chloride (0.9% NaCl) TKVO IV saline lock, flush with 2 ml 0.9% sodium chloride (0.9% NaCl) bid and prn Page 3 of 6
4 CONTINUE Discontinue order on page 6 Patient Supply* Self-Administer Keep at Bedside PATIENT CARE DERS ADMISSION DERS F HOME MEDICATIONS Prescribers: List ALL outpatient prescriptions, over the counter medications and herbal remedies the patient is taking at home (i.e. home medications ) at the time of admission and specify the status at admission (i.e. continue, discontinue or change). Order (1) changes in dose, route or frequency to home medications and (2) all new medications started on admission to hospital, on the New Admission Medication Orders section on page 6. Transcribers: Only transcribe medications that are identified as continue. Medication Name (Use generic names if possible) Dose (e.g. mg, mcg, units) Route (e.g. PO, SL, IM, topical, inhaled) Frequency (e.g. daily, bid, tid) (Include indication for prn medications) Change (write new Personal medications should be used when the patient has provided verbal consent and the medication is not listed in the hospital Formulary or the medication is a multi-dose preparation. Patients should use their personal eye drops and inhalers whenever possible. Personal topical multi-dose preparations should be kept at the bedside. Reviewed by: Entered by: Checked by: Page 4 of 6
5 PATIENT CARE DERS Thrombolytic Therapy Alteplase 0.9 mg/kg IV, total dose mg (maximum dose 90 mg) (Administer as per the 0.9 mg/kg alteplase Intravenous Infusion for Acute Ischemic Stroke Dosing Protocol for IV alteplase table) (see on reverse of page) Antiplatelets Acetylsalicylic acid enteric coated 81 mg PO daily when oral diet is ordered or Acetylsalicylic acid 80 mg by feeding tube daily when enteral diet is ordered. Start on (YYYY/MM/DD) at (hhmm) (Acetylsalicylic acid not recommended within 24 hours of alteplase administration) Acetylsalicylic acid 25 mg and dipyridamole XR 200 mg 1 capsule PO bid when oral diet is ordered. Start on (YYYY/MM/DD) at (hhmm) (Acetylsalicylic acid and dipyridamole not recommended within 24 hours of alteplase administration) Clopidogrel 75 mg PO/feeding tube daily when oral or enteral diet is ordered. Start on (YYYY/MM/DD) at (hhmm) (Clopidogrel not recommended within 24 hours of alteplase administration) Nicotine Replacement (Prescriber to complete Nicotine Replacement Therapy (NRT) Order Set (Adult)) Fever/Pain Management Acetaminophen 650 mg suppository PR q4 h prn for pain, fever, or temperature greater than 37.5 C while NPO Acetaminophen 650 mg PO/feeding tube q4 h prn for pain, fever, or temperature greater than 37.5 C when oral or enteral diet ordered Stroke Prevention Medications Atorvastatin mg PO/feeding tube daily when oral or enteral diet ordered Ramipril mg PO/feeding tube daily when oral or enteral diet ordered Hydrochlorothiazide mg PO/feeding tube daily when oral or enteral diet ordered Page 5 of 6
6 PATIENT CARE DERS Venous Thromboembolism (VTE) Prophylaxis No Pharmacological Prophylaxis Reason: Patient on therapeutic anticoagulation Other: Pharmacological Prophylaxis (APMS Warning in Effect) Dalteparin 5,000 units subcutaneously daily (recommended) Start on (YYYY/MM/DD) at (hhmm) (24 hours after alteplase initiation) Heparin 5,000 units subcutaneously q12 h (if creatinine clearance less than 30 ml/min) Start on (YYYY/MM/DD) at (hhmm) (24 hours after alteplase initiation) Additional New Medication Orders or Changes to Home Medications: Page 6 of 6
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