Curriculum Vitae. B. S. Department of Nutrition and Food Sciences

Transcription

1 Name: Young, Guang-Huar Curriculum Vitae Address: 2F.-1, No.6, Ln. 144, Anle Rd., Yonghe Dist., New Taipei City 23455, Taiwan (R.O.C.) Tel: Sex: Male Birth Date: 13 July Citizenship: Taiwan Birthplace: Taipei, Taiwan Educations 09/99-06/05 National Taiwan University, Taipei, Taiwan Ph. D. Institute of Microbiology and Biochemistry, Biochemistry Division 09/97-06/99 National Taiwan University, Taipei, Taiwan M. S. Institute of Agricultural Chemistry, Biochemistry Division 09/93-06/97 Fu-Jen Catholic University, Taipei, Taiwan Working Experience B. S. Department of Nutrition and Food Sciences 08/14-Present Department of Scientific Research, ENERGENESIS Biomedical Co. Ltd. Chief Scientific Officer 04/14-Present Taiwan Clinical Trial Consortium for Renal Diseases, Taiwan Executive Secretary 10/13-Present MediaTek-National Taiwan University Advanced Research Center, Taipei, Taiwan Technical Consultant 08/09-07/14 Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan Postdoctoral fellow 02/07-07/09 Institute of Molecular Biology, Academia Sinica, Nankang, Taipei Postdoctoral fellow 07/05-09/06 The Ministry of National Defense, Miaoli County Reserve Command, Taiwan Compulsory Military Service: Second Lieutenant, Chemical Officer. Expertise Nephrology, Proteomics, Biochemistry, Molecular Biology, Enzyme Chemistry Reviewer PLOS ONE 2013~ Editorial Board Member Journal of Nephrology Research (ISSN ) Honor The 50 th European Renal Association European Dialysis and Transplantation Association Best Abstracts presented by Young Authors

2 Published Paper 1. Guang-Huar Young, Jiun-Tsai Lin, Yi-Fang Cheng, Chun-Fang Huang, Cheng-Yu Chao, Jing-Yi Nong, Po-Ku Chen and Han-Min Chen, Identification of Adenine modulating AMPK activation in NIH/3T3 cells by Proteomic Approach. Journal of Proteomics 2015 Apr 29;120: (IF=3.929; R/C=16/78, BIOCHEMICAL RESEARCH METHODS) 2. Guang-Huar Young, Tao-Min Huang, Che-Hsiung Wu,Chun-Fu Lai, Chun-Cheng Hou, Kang-Yung Peng, Chan-Jung Liang, Shuei-Liong Lin, Shih-Chung Chang, Pi-Ru Tsai, Kwan-Dun Wu, Vin-Cent Wu*, Wen-Je Ko*, the NSARF group Mar 10;20 (8): Hemojuvelin modulates iron stress during acute kidney injury: improved by furin inhibitor. Antioxidants & Redox Signaling. (IF=7.667 ; R/C=27/291, BIOCHEMISTRY & MOLECULAR BIOLOGY; R/C= 9/123,ENDOCRINOLOGY & METABOLISM). 3. Chiao-Yin Sun, Guang-Huar Young, Yu-Ting Hsieh, Yau-Hung Chen, Mai-Szu Wu, Jia-Hung Lee, Chin-Chan Lee. Protein-bound uremic toxins induce tissue remodeling by targeting epidermal growth factor receptor. Journal of the American Society of Nephrology Jul 10. pii: ASN (IF=9.466;R/C=2/75,UROLOGY & NEPHROLOGY) 4. Chun-Fu Lai, Shuei-Liong Lin, Wen-Chih Chiang, Yung-Ming Chen, Vin-Cent Wu, Guang-Huar Young, Wen-Je Ko, Min-Liang Kuo, Tun-Jun Tsai, and Kwan-Dun Wu. Blockade of cysteine-rich protein 61 attenuates renal inflammation and fibrosis after ischemic kidney injury. The American Journal of Physiology-Renal Physiology Jun 11. pii: ajprenal (IF=3.3, R/C=15/75, UROLOGY & NEPHROLOGY) 5. Chan-Jung Liang, Wen-Ching Shen, Fu-Bing Chang, Vin-Cent Wu, Shu-Huei Wang, Guang-Huar Young, Jaw-Shiun Tsai, Ying-Chin Tseng, Yu-Sen Peng, Yuh-Lien Chen. Endothelial progenitor cells derived from Wharton's jelly of human umbilical cord attenuate ischemic acute kidney injury by increasing vascularization and decreasing apoptosis, inflammation, and fibrosis. Cell Transplantation May 9. (IF=3.57 ; R/C=5/26, TRANSPLANTATION) 6. Vin-Cent Wu, Cho-Kai Wu, Yi-Cheng Chang, Guang-Huar Young, Shann-Ching Chen, Wei-Shiung Yang, Chien-Yuan Chen, Wei-Jie Wang, Chien-Yu Lin, Yen-Hung Lin, Shuei-Liong Lin, Shih-Chieh Chueh, Kwan-Dun Wu,TAIPAI study group. Association of the variations in the HSD3[beta] gene with primary aldosteronism. Journal of Hypertension, 31(7): , July (IF=4.222, R/C=12/65, PERIPHERAL VASCULAR DISEASE) 7. Vin-Cent Wu*, Guang-Huar Young*, Po-Hsun Huang, Shyh-Chyi Lo, Kuo-Chuan Wang, Chiao-Yin Sun, Chan-Jung Liang, Tao-Ming Huang, Jou-Han Chen, Fan-Chi Chang, Yuh-Lien Chen, Yih-Shing Kuo, Jin-Bor Chen, Jaw-Wen Chen, Yung-Ming Chen, Wen-Jo Ko, Kwan-Dun Wu. In acute kidney injury, indoxyl sulfate impairs human endothelial progenitor cells: modulation by statin. Angiogenesis, 2013 Jul;16(3): doi:

3 /s (IF=4.41, R/C=10/65, PERIPHERAL VASCULAR DISEASE) 8. Wen-Ching Shen, Chan-Jung Liang, Vin-Cent Wu, Shu-Huei Wang, Guang-Huar Young, I-Rue Lai, Chung-Liang Chien, Seu-Mei Wang, Kwan-Dun Wu, and Yuh-Lien Chen. Endothelial progenitor cells derived from Wharton's jelly of the umbilical cord reduces ischemia-induced hind limb injury in diabetic mice by inducing HIF-1α/IL-8 expression. Stem Cells and Development, 2013 May 1;22(9): doi: /scd Epub 2013 Feb 15. (IF=4.202, R/C=3/26, TRANSPLANTATION) 9. Chih-Chung Shiao, Wen-Je Ko, Vin-Cent Wu, Tao-Min Huang, Chun-Fu Lai, Yu-Feng Lin, Chia-Ter Chao, Tzong-Shinn Chu, Hung-Bin Tsai, Pei-Chen Wu, Guang-Huar Young, Tze-Wah Kao, Jenq-Wen Huang, Yung-Ming Chen, Shuei-Liong Lin, Ming-Shou Wu, Pi-Ru Tsai, Kwan-Dun Wu, Ming-Jiuh Wang (2012, Aug). U-Curve Association between Timing of Renal Replacement Therapy Initiation and In-Hospital Mortality in Postoperative Acute Kidney Injury. PLoS One, doi: /journal.pone (IF=3.534; R/C=8/55, 10. Guang-Huar Young and Vin-Cent Wu (2012, Apr). KLOTHO methylation is linked to uremic toxins and chronic kidney disease. Kidney International 2012 Apr;81(7): doi: /ki (IF=8.52, R/C=3/73, UROLOGY & NEPHROLOGY) 11. Yi-Chen Lin, Han-Min Chen, I-Min Chou, An-Na Chen, Chia-Pei Chen, Guang-Huar Young, Chi-Tsai Lin, Chiung-Hsiang Cheng, Shih-Chung Chang, Rong-Huay Juang (2012, Apr). Plastidial Starch Phosphorylase in Sweet Potato Roots Is Proteolytically Modified by Protein-Protein Interaction with the 20S Proteasome. PLoS One, 7:e (IF=3.534; R/C=8/55, 12. Vin-Cent Wu, Chun-Fu Lai, Chih-Chung Shiao, Yu-Feng Lin, Pei-Chen Wu, Chia-Ter Chao, Fu- Chang Hu, Tao-Min Huang, Yu-Chang Yeh, I-Jung Tsai, Tze-Wah Kao, Yin-Yi Han, Wen-Chung Wu,Chun-Cheng Hou, Guang-Huar Young, Wen-Je Ko, Tun-Jun Tsai, Kwan-Dun Wu (2012, Mar). Effect of Diuretic Use on 30-Day Postdialysis Mortality in Critically Ill Patients Receiving Acute Dialysis. PLoS One, 7:e (IF=3.534; R/C=8/55, 13. Vin-Cent Wu, Tao-Min Huang, Pei-Chen Wu, Wei-Jie Wang, Chia-Ter Chao, Shao-Yu Yang, Chih- Chung Shiao, Fu-Chang Hu, Chun-Fu Lai, Yu-Feng Lin, Yin-Yi Han, Yih-Sharng Chen, Ron-Bin Hsu, Guang-Huar Young, Shoei-Shen Wang, Pi-Ru Tsai, Yung-Ming Chen, Ting-Ting Chao, Wen-Je Ko, Kwan-Dun Wu, the NSARF Group (2012, Jan). Preoperative Proteinuria Is Associated with Long-Term Progression to Chronic Dialysis and Mortality after Coronary Artery Bypass Grafting Surgery. PLoS One, 7:e (IF=3.534; R/C=8/55, 14. Vin-Cent Wu, Tao-Min Huang, Chun-Fu Lai, Chih-Chung Shiao, Yu-Feng Lin, Tzong-Shinn

4 Chu,Pei-Chen Wu, Chia-Ter Chao, Jann-Yuan Wang, Tze-Wah Kao, Guang-Huar Young, Pi-Ru Tsai,Hung-Bin Tsai, Chieh-Li Wang, Ming-Shou Wu, Wen-Chih Chiang, I-Jung Tsai, Fu-Chang Hu, Shuei-Liong Lin, Yung-Ming Chen, Tun-Jun Tsai, Wen-Je Ko and Kwan-Dun Wu, on behalf of the NSARF Group (2011, Aug). Acute-on-chronic kidney injury at hospital discharge is associated with long-term dialysis and mortality. Kidney International, 7:e (IF=8.52, R/C=3/73, UROLOGY & NEPHROLOGY) 15. Yu-Hsiang Chou, Tao-Min Huang, Vin-Cent Wu, Cheng-Yi Wang, Chih-Chung Shiao, Chun-Fu Lai, Hung-Bin Tsai, Chia-Ter Chao, Guang-Huar Young, Wei-Jei Wang, Tze-Wah Kao, Shuei-Liong Lin, Yin-Yi Han, Anne Chou, Tzu-Hsin Lin, Ya-Wen Yang, Yung-Ming Chen, Pi-Ru Tsai, Yu-Feng Lin, Jenq-Wen Huang, Wen-Chih Chiang, Nai-Kuan Chou, Wen-Je Ko6, Kwan-Dun Wu, Tun-Jun Tsai1 and the NSARF Study Group (2011, Jun). Impact of timing of renal replacement therapy initiation on outcome of septic acute kidney injury. Critical Care, 15:R134. (IF=5.035, R/C=5/27, CRITICAL CARE MEDICINE) 16. Tao-Min Huang*, Vin-Cent Wu*, Guang-Huar Young, Yu-Feng Lin, Chih-Chung Shiao, Pei-Chen Wu, Wen-Yi Li, Hsi-Yu Yu, Fu-Chang Hu, Jou-Wei Lin, Yih-Sharng Chen, Yen-Hung Lin, Shoei-Shen Wang, Ron-Bin Hsu, Fan-Chi Chang, Nai-Kuan Chou, Tzong-Shinn Chu, Yu-Chang Yeh, Pi-Ru Tsai, Jenq-Wen Huang, Shuei-Liong Lin, Yung-Ming Chen, Wen-Je Ko and Kwan-Dun Wu (2010, Nov). Preoperative Proteinuria Predicts Adverse Renal Outcomes after Coronary Artery Bypass Grafting. Journal of the American Society of Nephrology, 22(1): (I F=9.466, R/C=2/73, UROLOGY & NEPHROLOGY) 17. Chih-Chung Shiao, Vin-Cent Wu, Wen-Yi Li, Yu-Feng Lin, Fu-Chang Hu, Guang-Huar Young (2009, Oct). Late initiation of renal replacement therapy is associated with worse outcomes in acute kidney injury after major abdominal surgery. Critical Care, 13:R171. (IF=5.035, R/C=5/27, CRITICAL CARE MEDICINE) 18. Guang-Huar Young, Han-Min Chen, Chi-Tsai Lin, Kuang-Ching Tseng, Jiann-Shing Wu, Rong-Huay Juang (2006, Feb). Site-specific phosphorylation of L-form starch phosphorylase by the protein kinase activity from sweet potato roots. Planta, 223: (IF=3.376, R/C=26/196, PLANT SCIENCES). Conference 1. Guang-Huar Young and Vincent Wu (2014).The strategy of renin-angiotensin system blockers reduce the indoxyl sulfate-mediated renal damage on the duration of acute kidney injury. The 14th Asian Pacific Congress of Nephrology (APCN2014) Tokyo, Japan. 2. Guang-Huar Young, Hung-Bin Tsai, Tao-Min Huang and Vincent Wu (2012, Oct). Soluble hemojuvelin, an early biomarker promotes iron deposition during acute kidney injury. The

5 45rd American Society of Nephrology (ASN) Annual Meeting and Scientific Exposition, San Diego, CO, USA. 3. Guang-Huar Young, Vin-Cent Wu, Fu-Chang Hu, Wen-Je Ko, Kwan-Dun Wu (2011, Sep). Effect of diuretic use on mortality in critical ill patients receiving acute dialysis. The 29th International Society of Blood Purification (ISBP) Annual Meeting, Beijing, China. 4. Guang-Huar Young, Vin-Cent Wu, Hung-Bin Tsai and Wen-je Ko (2010, Nov). Repulsive Guidance Molecule C Is an Early Predicted Biomarker in Diagnosis of Acute Kidney Injury. The 43rd American Society of Nephrology (ASN) Annual Meeting and Scientific Exposition, Denver, CO, USA. 5. Ming F. Tam and Guang-Huar Young (2008) Yeast Rpl12p Affects the Translation of a Selected Group of mrnas. 22nd Annual Symposium of the Protein Society, San Diego, USA. 6. Guang-Huar Young, Li-Fan Liu, and Ming F. Tam (2009) Rpl12bp is functionally distinct from rpl12ap. 12th International Symposium of SCBA, Taipei, Taiwan. 7. Guang-Huar Young, Han-Min Chen, Chi-Tsai Lin, Rong-Huay Juang (2005) Site-specific phosphorylation of L-form starch phosphorylase by a protein kinase activity from sweet potato roots. 9th IUBMB Conference, Budapest, Hungary. 8. Guang-Huar Young and Rong-Huay Juang (2000) The purification and functional assays of protein kinases from sweet potato roots. 17th Joint Annual Conference of Biochemical Sciences, Nantou, Taiwan.