AMERICAN BOARD OF PSYCHIATRY AND NEUROLOGY, INC. SUBSPECIALTY CERTIFICATION EXAMINATION IN EPILEPSY MEDICINE
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1 SUBSPECIALTY CERTIFICATION EXAMINATION IN EPILEPSY MEDICINE 2014 Content Blueprint (November 26, 2012) Number of questions: 200 I. Classification 7 9% II. Routine EEG 16 20% III. Evaluation 22 26% IV. Management 38 42% V. Systems-based practice issues 1 3% VI. Mechanisms of the epilepsies 7 9% TOTAL 100% Note: A more detailed content outline is shown below ABPN Content Specifications Page 1 of 9 Posted: December 3, 2013
2 SUBSPECIALTY CERTIFICATION EXAMINATION IN EPILEPSY MEDICINE 2014 Content Outline Content areas I. Classification A. Classification of the seizures 1. Generalized a. Tonic clonic (in any combination) b. Absence i. Typical ii. Atypical iii. Absence with special features a) Myoclonic absence b) Eyelid myoclonia c. Myoclonic i. Myloclonic ii. Myoclonic atonic iii. Myoclonic tonic d. Clonic e. Tonic f. Atonic 2. Focal a. Without impairment of consciousness/ responsiveness i. With observable motor or autonomic components (roughly corresponds to the concept of simple partial seizure ) ii. Involving subjective sensory or psychic phenomena only (corresponds to the concept of complex partial seizure ) b. With impairment of consciousness/ responsiveness (roughly corresponds to the concept of complex partial seizure ) c. Evolving to a bilateral, convulsive seizure (involving tonic, clonic or tonic and clonic components: replace the term secondarily generalized seizure ) 2014 ABPN Content Specifications Page 2 of 9 Posted: December 3, 2013
3 3. May be focal, generalized, or unclear a. Epileptic spasms B. Electro-clinical syndromes and other epilepsies 1. By age of onset a. Neonatal period i. Benign familial neonatal seizures (BFNS) ii. Early myoclonic encephalopathy (EME) iii. Ohtahara syndrome b. Infancy i. Migrating partial seizures of infancy ii. West syndrome iii. Myoclonic epilepsy in infancy (MEI) iv. Benign infantile seizures v. Benign familial infantile seizures vi. Dravet syndrome vii. Myoclonic encephalopathy in nonprogressive disorders c. Childhood i. Febrile seizures (FS+) (can start in infancy) ii. Early onset benign childhood occipital epilepsy (Panayiotopoulos type) iii. with myoclonic atonic (previously astatic seizures) iv. Benign epilepsy with centrotemporal spikes (BECTS) v. Autosomal-dominant nocturnal frontal lobe epilepsy (ADNFLE) vi. Late-onset childhood occipital epilepsy (Gastaut type) vii. with myoclonic absences viii. Lennox-Gastaut syndrome ix. Epileptic encephalopathy with continuous spike-andwave during sleep (CSWS), including Landau- Kleffner syndrome (LKS) x. Childhood absence epilepsy (CAE) d. Adolescence Adult i. Juvenile absence epilepsy (JAE) 2014 ABPN Content Specifications Page 3 of 9 Posted: December 3, 2013
4 ii. Juvenile myoclonic epilepsy (JME) iii. with generalized tonic-clonic seizures alone iv. Progressive myoclonus epilepsies (PME) v. Autosomal dominant partial epilepsy with auditory features (ADPEAF) vi. Other familial temporal lobe epilepsies C. Less specific age relationship 1. Familial focal epilepsy with variable foci (childhood to adult) 2. Reflex epilepsies D. Distinctive constellations 1. Mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE with HS) 2. Rasmussen syndrome 3. Gelastic seizures with hypothalamic hamartoma E. Epilepsies attributed to and organized by structural-metabolic causes 1. Structural (including tumors, vascular malformations) 2. Infection 3. Trauma 4. Perinatal insults 5. Stroke 6. Malformations of cortical development a. Neurocutaneous disorders 7. Mitochondrial and metabolic disorders F. Epilepsies of unknown cause G. Conditions with epileptic seizures traditionally not diagnosed as a form of epilepsy 1. Benign neonatal seizures (BNS) 2. Febrile seizures (FS) H. Nonepiletic paroxysmal disorders: 1. Breath holding spells 2. Cardiac etiologies: e.g. prolonged QT intervals 3. Convulsive 4. Reflux and Sandifer syndrome 5. Syncopal events 6. Gratification phenomena and masturbation 7. Shuddering/shivering 2014 ABPN Content Specifications Page 4 of 9 Posted: December 3, 2013
5 II. III. 8. Acute confusional migraine 9. Benign infantile myoclonus 10. Nonepileptic seizures I. Epidemiology Routine EEG A. Normal 1. Activation and procedures 2. Benign variants 3. Artifacts and technical issues B. Interictal epileptiform patterns C. Ictal patterns (localization, status, hypsarrhythmia, ictal neonatal seizures) D. Encephalopathic patterns Evaluation A. History, examination, and semiology B. Chemical and metabolic screening C. Specialized EEG 1. Other supplementary and ambulatory 2. Video EEG 3. Invasive EEG recordings a. Depth electrodes b. Subdural grid electrodes c. Corticography i. Functional mapping D. Imaging 1. Choice of structural imaging (CT, MRI) a. Specific protocols 2. Functional imaging a. SPECT b. PET c. MEG d. MRS e. fmri f. Diffusion tensor imaging E. Neuropsychological testing F. Spinal fluid analysis (lumbar puncture) 2014 ABPN Content Specifications Page 5 of 9 Posted: December 3, 2013
6 IV. G. Genetic analysis Management A. Principles of management 1. History of new-onset seizure(s) 2. Acute seizure management 3. Monotherapy vs. polytherapy 4. Antiepileptic drug selection 5. Dosing and drug monitoring 6. Comorbidities (e.g., psychiatric issues, cognitive issues) 7. Special situations a. Neonate b. Developmental delay c. Cognitively impaired d. Women with epilepsy e. Elderly f. Systemic illness i. Hypoxia-ischemia 8. Discontinuation of medication 9. Mortality a. SUDEP B. Antiepileptic therapies 1. Specific drugs (regular and extended-release formulations) a. Acetazolamide b. ACTH c. Carbamazepine d. Clonazepam e. Clorazepate f. Diazepam (oral and rectal gel) g. Divalproex sodium h. Ethosuximide i. Felbamate j. Gabapentin k. Lacosamide l. Lamotrigine m. Levetiracetam n. Lorazepam 2014 ABPN Content Specifications Page 6 of 9 Posted: December 3, 2013
7 o. Oxcarbazepine p. Phenobarbital q. Phenytoin r. Pregabalin s. Primidone t. Rufinamide u. Tiagabine v. Topiramate w. Valproate x. Vigabatrin y. Zonisamide z. Ezogabine aa. Clobazam 2. Mechanisms of action of above drugs 3. Drug interactions (pharmacokinetic/ pharmacodynamic 4. Drug toxicities and teratogenicity 5. Monitoring principles 6. Other therapies a. Diet therapies i. Indications ii. Patient selection iii. Monitoring iv. Duration b. Hormonal therapies i. ACTH ii. Other steroidal therapies c. Immunoglobulin therapy d. Vagus nerve stimulation e. Other forms of stimulation f. Alternative and complementary therapies C. Surgical therapies 1. Indications for referral a. Definition of intractable epilepsies b. Duration of epilepsy and failure of response to medication 2. Evaluation for possible surgery a. WADA and special neuropsychological evaluation 2014 ABPN Content Specifications Page 7 of 9 Posted: December 3, 2013
8 3. Types of surgical procedure a. Focal resections i. Temporal lobe ii. Frontal lobe iii. Parietooccipital b. Hemispherectomies i. Neocortical ii. Standard anterior temporal lobectomy iii. Selective mesial resections c. Multiple subpial transections d. Corpus callosotomies e. Repeat surgical procedures f. Other 4. Complications of surgery a. Outcome D. Status epilepticus 1. Classification (types) a. Generalized convulsive b. Focal, including epilepsia partialis continua (EPC) c. Nonconvulsive d. Refractory 2. Management a. Acute management b. Drug therapy i. First-line ii. Second-line iii. Third-line c. Anesthetic therapies d. Continuous EEG monitoring 3. Systemic complications 4. Outcome E. Psychosocial management 1. Patient and family education a. Drug information b. Compliance c. Safety issues 2014 ABPN Content Specifications Page 8 of 9 Posted: December 3, 2013
9 i. Sleep deprivation ii. Sports participation iii. Drug and alcohol risks iv. Driving regulations v. Piloting regulations 2. School and work situations a. IEPs b. ADA c. Disability 3. Quality of life a. Dating b. Marriage c. Stigma 4. Sleep and epilepsy 5. Prognosis and counseling V. Systems-based practice issues A. Public policy issues (education, driving, research funding) B. Working with educational systems C. Employment issues D. Clinical trials of new therapies E. Forensic epilepsy F. Ethics VI. Mechanisms of the epilepsies A. Pathophysiology of the epilepsies B. Animal models C. Physiological basis of epileptic EEG patterns D. Pathology of the epilepsies E. Genetic basis of the epilepsies 2014 ABPN Content Specifications Page 9 of 9 Posted: December 3, 2013
SUBSPECIALTY CERTIFICATION EXAMINATION IN EPILEPSY MEDICINE Content Blueprint (December 21, 2015)
SUBSPECIALTY CERTIFICATION EXAMINATION IN EPILEPSY MEDICINE 2016 Content Blueprint (December 21, 2015) Number of questions: 200 1. Classification 8-12% 2. Routine EEG 16-20% 3. Evaluation 23-27% 4. Management
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