PET myocard perfusion & viability Riemer Slart
|
|
- Roland Goodwin
- 5 years ago
- Views:
Transcription
1 PET myocard perfusion & viability Riemer Slart Nuclear Medicine Physician Dept. of Nuclear Medicine and Molecular Imaging University Medical Center Groningen, the Netherlands Professor in Molecular Imaging, University of Twente, the Netherlands EANM Cardiovascular committee
2 Global burden of cardiovascular disease Cardiovascular disease is the leading cause of death worldwide Nature, 493, S2 S3, 2013
3 Global Coronary & Cardiovascular Risk Scores Greenland. J Am Coll Cardiol. 2010;56:e50-e103.
4 What cardiologists want to know: Does the patient have a CAD? CAD with a significant stenosis? What is the extend of the CAD? Of prognostic impact? What is the best therapy? Slide 4
5 The general gatekeeper principle Coronary artery disease Low risk (<1%) Risk factors Clinics Noninvasive imaging Intermediate risk (1-3%) High risk (>3%)
6 Ischemic cascade CAD
7 Coronary stenosis & ischemia Diameter stenosis 50% Dilemma: no perfect match Patient with ischemia Patient with angiographic lesion
8 Coronary stenosis & ischemia Diameter stenosis 90% Dilemma: no perfect match Patient with ischemia Patient with angiographic lesion
9 Diagnosis of CAD: CVI techniques Non-invasive ECG Echocardiogram Dobu MRI MPS SPECT MPS PET Adenosine MRI CT angiography Calcium scoring Invasive Intracoronary echo Coronary angiogram
10 Indications of different imaging tests for the diagnosis of obstructive CAD and for the assessment of prognosis in subjects without known CAD Guidelines on myocardial perfusion, Task Force ESC and EACTS, Eur H J 2010
11 PET(/CT) myocardial perfusion PET-CT scanner PET vs SPECT Pro s: Better resolution Absolute quantification Real time imaging Con s : Costs Availability
12 PET tracers for myocardial perfusion
13 Sogbein et al Biomed Res Int. 2014
14 Absolute quantification 13 N-ammonia: Hutchins model 3-compartments model (K1, K2, K3) 13 N-ammonia free diffusible 13 N-ammonia: glutamate into glutamin (synthetasis) equilibrium Absolute quantification: ml/gr/min
15 Myocardial Blood Flow (absolute values, ml/g/min) Time-activity curves
16 Normal values 13 N-ammonia Rest: ml/min/100g Stress: ml/min/100g In general: MPR > 2.0 Depending on age and gender & technique Blanksma et al., J Nucl Med 1995 Chilian WM, Circulation 1997 DeGrado et al, J Nucl Cardiol 1996 Muzik et al, J Am Coll Cardiol 1998
17 DIFFERENT SOFTWARE PACKAGES -PMOD, SYNGO, FLOWQUANT- Sunderland et al, J Nucl Cardiol 2014
18 Dynamic 13 N-ammonia PET: quantification (Syngo) ml/gr/min
19 Principle MPI/FDG PET scan -Visual analysis- Uptake flowtracer Rest Stress NORMAL tissue normal normal INFARCTED tissue reduced reduced ISCHEMIC tissue normal reduced
20 Preparation patient: Glucose load, low fat? Euglycaemic insulin clamp infusion system Acipimox: fatty acid lowering agent (aspirin needed)
21 PET protocol: ischemia & viability UMC Groningen Viability Viability & ischemia rest 13 NH 3 rest 13 NH 3 (gated) FDG adeno 13 NH 3 (gated) FDG
22 Shorter scan protocol? Residual activity correction (RAC) Lazarenko SV et al, Med Center Alkmaar, NL
23 PET Imaging Flow/FDG Patterns Normal DCM Hibernating Scar Match Mismatch Match
24 Viability testing rest 99m Tc-tetrofosmin IQ SPECT and FDG cpet 99m Tc-tetrofosmin IQ SPECT FDG cpet CABG MVP/ring
25 Case 67 yr male RF: hypertension, DM Dyspnoe, no angina Obese Previous MPS SPECT (MIBI) inconclusive Nevertheless ischemia? rest, stress 13 N-ammonia and (gated) FDG
26 Rest, stress 13 N-ammonia and (gated) FDG
27 Polarmap and quantification
28 Results Rest: 52 ml/min/100g Stress: 68 ml/min/100g MPR: 1.27 (normal > 2) Regions: 5 regions ratio < 1
29 Coronary angiography 3 vessel disease: revascularisation
30 Prognostic value of MPR without intervention -Absolute quantification- Tio, Slart et al., J Nuc Med 2010
31 Prognostic value of MPR after intervention -Absolute quantification- Cardiac death MACE Slart et al, J Nucl Med 2011
32 Absolute flow or myocardial flow reserve for the detection of significant coronary artery disease? 15 O-water PET study 104 patients with moderate pre-test likelihood of CAD without previous myocardial infarction. Reference: CAG Joutsiniemi et al, Eur Heart J Cardiovasc Imag 2015
33 PERFUSION DEFECT SIZE ON MPI PET MULTICENTER TRIAL N = 7000 Dorbola et al, J Am Coll Cardiol, 2013
34 Diagnostic Performance of MPI Using SPECT, cmri, and PET Imaging for the Detection of Obstructive CAD: A Meta-Analysis 166 articles (n = 17,901) : 114 SPECT, 37 CMR, and 15 PET articles. Jaarsma et al., J Am Coll Cardiol, 2012
35 PET vs MRI MPI Morton et al, J Am Coll Cardiol 2012
36
37 New developments
38 Flurpiridaz PET phase 3 study PET vs SPECT for overall CAD detection (n=755) Screened 920 Dosed 795 Discontinued 31 PET evaluable 782 SPECT evaluable 778 Angio evaluable 762 Total 755 SPECT+PET+ angio CAD+= 327 CAD-= 428 (CAD prev 43%) Courtesy of J. Knuuti
39 Flurpiridaz PET phase 3 study PET vs SPECT for overall CAD detection (n=755) Original read Re-read Courtesy of J. Knuuti
40 Courtesy of J. Knuuti
41 Sr/Rb generator Ammonia mini cyclotron
42
43 Hybrid cardiac imaging: SPECT/CT and PET/CT. A joint position statement by the European Association of Nuclear Medicine (EANM), the European Society of Cardiac Radiology (ESCR) and the European Council of Nuclear Cardiology (ECNC) Eur J Nucl Med & Mol Imag 2011
Hybrid cardiac imaging Advantages, limitations, clinical scenarios and perspectives for the future
Hybrid cardiac imaging Advantages, limitations, clinical scenarios and perspectives for the future Prof. Juhani Knuuti, MD, FESC Turku, Finland Disclosure: Juhani Knuuti, M.D. Juhani Knuuti, M.D. has financial
More informationSPECT or PET for Cardiovascular Screening in High-Risk Patients
SPECT or PET for Cardiovascular Screening in High-Risk Patients Paeng, Jin Chul MD PhD Department of Nuclear Medicine Seoul National University Hospital Contents Recent Development in SPECT and PET Technology
More informationCT or PET/CT for coronary artery disease
CT or PET/CT for coronary artery disease Rotterdam 2012 Juhani Knuuti, MD, PhD, FESC Turku PET Centre University of Turku Turku, Finland Juhani.knuuti@utu.fi Turku PET Centre University of Turku Åbo Akademi
More informationMyocardial Perfusion: Positron Emission Tomography
Myocardial Perfusion: Positron Emission Tomography TH. Schindler, MD University Hospitals of Geneva, Cardiovascular Center, Geneva, Switzerland ESC 2010 Stockholm Personal Disclosure Research Grant support
More informationImaging ischemic heart disease: role of SPECT and PET. Focus on Patients with Known CAD
Imaging ischemic heart disease: role of SPECT and PET. Focus on Patients with Known CAD Hein J. Verberne Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands International Conference
More informationPearls & Pitfalls in nuclear cardiology
Pearls & Pitfalls in nuclear cardiology Maythinee Chantadisai, MD., NM physician Division of Nuclear Medicine, Department of radiology, KCMH Principle of myocardial perfusion imaging (MPI) Radiotracer
More information1. LV function and remodeling. 2. Contribution of myocardial ischemia due to CAD, and
1 The clinical syndrome of heart failure in adults is commonly associated with the etiologies of ischemic and non-ischemic dilated cardiomyopathy, hypertrophic cardiomyopathy, hypertensive heart disease,
More informationSPECT CT Current Status and Future Direction Nuclear Cardiology
SPECT CT Current Status and Future Direction Nuclear Cardiology BIR London 25 th February 2013 Nik Sabharwal Consultant Cardiologist Oxford Heart Centre nikant.sabharwal@ouh.nhs.uk No conflict of interest
More informationOptimal testing for coronary artery disease in symptomatic and asymptomatic patients
Optimal testing for coronary artery disease in symptomatic and asymptomatic patients Alexandre C Ferreira, MD Clinical Chief of Cardiology Jackson Health System Director, Interventional Cardiology Training
More informationHow to investigate (Cardiac) Chest Pain
RCP UPDATE IN MEDICINE 27 th November 2017 How to investigate (Cardiac) Chest Pain Justin Carter Consultant Cardiologist North Tees and Hartlepool NHS Trust The spectrum of coronary disease No Disease
More informationThe Role of Nuclear Imaging in Heart Failure
The Role of Nuclear Imaging in Heart Failure Mouaz H. Al-Mallah, MD MSc FESC Associate Professor of Medicine Consultant Cardiologist and Division Head, Cardiac Imaging King Abdulaziz Cardiac Centre, National
More informationLe FDG dans l évaluation de la viabilité : Quelle place par rapport aux autres traceurs?
Le FDG dans l évaluation de la viabilité : Quelle place par rapport aux autres traceurs? Pierre-Yves MARIE, Médecine Nucléaire, CHU de Nancy PET Gated-SPECT MRI FDG imaging: effect of dietary status fasting
More informationLong-term outcome after normal myocardial perfusion imaging in suspected ischaemic heart disease
Dan Med J 65/2 February 2018 DANISH MEDICAL JOURNAL 1 Long-term outcome after normal myocardial perfusion imaging in suspected ischaemic heart disease Pia Hedegaard Johnsen 1, Martin Berg Johansen 1, 2
More informationUse of Nuclear Cardiology in Myocardial Viability Assessment and Introduction to PET and PET/CT for Advanced Users
Use of Nuclear Cardiology in Myocardial Viability Assessment and Introduction to PET and PET/CT for Advanced Users February 1 5, 2011 University of Santo Tomas Hospital Angelo King A-V Auditorium Manila,
More informationTechnical Meeting on: Current Role of Nuclear Cardiology in the Management of Cardiac Diseases Vienna, May 2008 Vienna International Centre
Technical Meeting on: Current Role of Nuclear Cardiology in the Management of Cardiac Diseases Vienna, 5-95 9 May 2008 Vienna International Centre Evidence-based Nuclear Cardiology: Imaging of CAD The
More informationCardiology for the Practitioner Advanced Cardiac Imaging: Worth the pretty pictures?
Keenan Research Centre Li Ka Shing Knowledge Institute Cardiology for the Practitioner Advanced Cardiac Imaging: Worth the pretty pictures? Howard Leong-Poi, MD, FRCPC Associate Professor of Medicine St.
More informationMyocardial blood flow PET evaluation and quantification. Dr. Erick Alexánderson. Rosas
Myocardial blood flow PET evaluation and quantification Dr. Erick Alexánderson Rosas Clinical case 62 year old female patient with a history of DM2 and chronic systemic hypertension She complains of progressive
More informationMD F A F C A C MAS A N S C
Myocardial Perfusion Imaging and Coronary Calcium Scoring: Complimentary or Competitive David Wolinsky MD FACC MASNC Section Head Nuclear Cardiology, Cleveland Clinic Florida Immediate Past President,
More informationEmerging role of PET in nuclear cardiology. Dr. Erick Alexánderson. Rosas
Emerging role of PET in nuclear cardiology Dr. Erick Alexánderson Rosas PET principles e + e - 180 PET/CT Cyclotron Unit UNAM Cyclotron Radiopharmacy PET Camera CT PET PET CT Perfusion Anatomic evaluation
More informationCHRONIC CAD DIAGNOSIS
CHRONIC CAD DIAGNOSIS Chest Pain Evaluation 1. Approach to diagnosis of CAD 2. Classification of chest pain 3. Pre-test likelihood CAD 4. Algorithm for chest pain evaluation in women 5. Indications for
More informationCalcium scoring Clinical and prognostic value
Calcium scoring Clinical and prognostic value Matthijs Oudkerk Professor and Chair of Radiology University Medical Center Groningen, University of Groningen Groningen, The Netherlands Sofia 2011 13 May
More informationDiagnosis of CAD S Richard Underwood
Diagnosis of CAD S Richard Underwood Professor of Cardiac Imaging Royal Brompton Hospital & Imperial College Faculty of Medicine London, UK The history and diagnosis 89% Non-cardiac chest pain 50% Atypical
More informationNUCLEAR CARDIOLOGY UPDATE
Nuclear Cardiology David K. Shelton, Jr., MD NUCLEAR CARDIOLOGY UPDATE No Conflicts. No Disclosures. No Smoking. David K. Shelton UCDMC Nuclear Cardiology Nuclear Cardiology Radionuclide Ventriculography
More informationSung A Chang Department of Internal Medicine, Division of Cardiology, Sungkyunkwan University School of Medicine, Samsung Medical Center
CMR Perfusion and Viability A STICH Out of Time? Sung A Chang Department of Internal Medicine, Division of Cardiology, Sungkyunkwan University School of Medicine, Samsung Medical Center Can Imaging Improve
More informationCurrent and Future Imaging Trends in Risk Stratification for CAD
Current and Future Imaging Trends in Risk Stratification for CAD Brian P. Griffin, MD FACC Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic Disclosures: None Introduction
More informationConflict of Interest Disclosure
Comparative Advantages of PET Over SPECT: Is PET Really Better? Timothy M. Bateman M.D. Co-Director, Cardiovascular Radiologic Imaging Mid America Heart Institute Professor of Medicine University of Missouri-Kansas
More informationRational use of imaging for viability evaluation
EUROECHO and other imaging modalities 2011 Rational use of imaging for viability evaluation Luc A. Pierard, MD, PhD, FESC, FACC Professor of Medicine Head, Department of Cardiology, CHU Liège, Belgium
More informationJe bénéficie régulièrement de fonds privés, dans le cadre de projets de recherche ou d activités de formation.
Je bénéficie régulièrement de fonds privés, dans le cadre de projets de recherche ou d activités de formation. Ces fonds proviennent essentiellement d industriels travaillant dans les domaines de l imagerie
More informationSPECT-CT: Τι πρέπει να γνωρίζει ο Καρδιολόγος
SPECT-CT: Τι πρέπει να γνωρίζει ο Καρδιολόγος Δρ Αναστασία Κίτσιου Διευθύντρια, Καρδιολογική Κλινική, Σισμανόγλειο ΓΝΑ Chair, Education Committee, Section on Nuclear Cardiology & Cardiac CT, EACVI, ESC
More informationPatient referral for elective coronary angiography: challenging the current strategy
Patient referral for elective coronary angiography: challenging the current strategy M. Santos, A. Ferreira, A. P. Sousa, J. Brito, R. Calé, L. Raposo, P. Gonçalves, R. Teles, M. Almeida, M. Mendes Cardiology
More informationWomen and Coronary Artery Disease:
Women and Coronary Artery Disease: Less is More? Interventional Cardiology 2017 32 th Annual International Symposium Snow Mass March 5-10 Yolande Appelman MD, PhD,FESC EAPCI-Women Interventional Cardiologist
More informationPET: quantification of perfusion and beyond
PET: quantification of perfusion and beyond Juhani Knuuti Turku PET Centre University of Turku Turku, Finland Juhani.knuuti@utu.fi 27.8.2012 1 Disclosure: Juhani Knuuti, M.D. Juhani Knuuti, M.D. has financial
More informationCardiac PET. John Buscombe
Cardiac PET John Buscombe Why PET? Improved resolution-not really required in cardiology Improved sensitivity this may be important-financially as reduced acquisition time Improved attenuation correction-good
More informationPET for the Evaluation of Myocardial Viability
PET for the Evaluation of Myocardial Viability Myocardial viability assessment is an important part of cardiac PET to assist physicians to decide upon the best surgical or medical procedures. F-18 FDG
More informationCombining Coronary Artery Calcium Scanning with SPECT/PET Myocardial Perfusion Imaging
Combining Coronary Artery Calcium Scanning with SPECT/PET Myocardial Perfusion Imaging Daniel S. Berman, MD Director, Cardiac Imaging Cedars-Sinai Heart Institute Professor of Medicine and Imaging Cedars-Sinai
More informationCMR stress Perfusion: what's new?
CMR stress Perfusion: what's new? John P. Greenwood Professor of Cardiology, Leeds University, UK Consultant Cardiologist Leeds Teaching Hospitals NHS Trust, UK CMR: multi-parametric CMR: multi-parametric
More informationAtypical pain and normal exercise test
Atypical pain and normal exercise test F. Mut, M. Beretta Nuclear Medicine Service, Asociacion Española Montevideo, Uruguay Clinical history 67-year old male with several coronary risk factors. Atypical
More informationPromising New Fluorine-18 Labeled Tracers for PET Myocardial Perfusion Imaging
Journal of Nuclear Medicine, published on July 30, 2015 as doi:10.2967/jnumed.115.161661 Promising New Fluorine-18 Labeled Tracers for PET Myocardial Perfusion Imaging Richard C. Brunken MD, FACC, FAHA,
More informationFFR Incorporating & Expanding it s use in Clinical Practice
FFR Incorporating & Expanding it s use in Clinical Practice Suleiman Kharabsheh, MD Consultant Invasive Cardiology Assistant professor, Alfaisal Univ. KFHI - KFSHRC Concept of FFR Maximum flow down a vessel
More informationNew Insight about FFR and IVUS MLA
New Insight about FFR and IVUS MLA Can IVUS MLA Predict FFR
More informationMultisclice CT in combination with functional imaging for CAD. Temporal Resolution. Spatial Resolution. Temporal resolution = ½ of the rotation time
Multisclice CT in combination with functional imaging for CAD Prof. Juhani Knuuti, MD, FESC Turku University Hospital and University of Turku Turku, Finland MSCT and functional imaging for CAD Practical
More informationDetection Of Functional Significance of Coronary Stenoses Using Dynamic. Values Of Myocardial Blood Flow And Coronary Flow Reserve
The 2nd International Symposium on Physics, Engineering and Technologies for Biomedicine Volume 2018 Conference Paper Detection Of Functional Significance of Coronary Stenoses Using Dynamic 13 N-Ammonia
More informationFFR in Multivessel Disease
FFR in Multivessel Disease April, 26 2013 Coronary Physiology in the Catheterization Laboratory Location: European Heart House, Nice, France Pim A.L. Tonino, MD, PhD Hartcentrum, Eindhoven, the Netherlands
More informationF-FDG PET/CT in Myocardial Viability
18 F-FDG PET/CT in Myocardial Viability H Verberne, Academic Medical Centre, Amsterdam S van Eeckhoudt, Bravis ziekenhuis, Roosendaal 1. Introduction Patients with multi-vessel coronary artery disease
More informationΣεμινάριο Ομάδων Εργασίας Fractional Flow Reserve (FFR) Σε ποιούς ασθενείς; ΔΗΜΗΤΡΗΣ ΑΥΖΩΤΗΣ Επιστ. υπεύθυνος Αιμοδυναμικού Τμήματος, Βιοκλινική
ΕΛΛΗΝΙΚΗΚΑΡΔΙΟΛΟΓΙΚΗΕΤΑΙΡΕΙΑ Σεμινάριο Ομάδων Εργασίας 2011 Fractional Flow Reserve (FFR) Σε ποιούς ασθενείς; ΔΗΜΗΤΡΗΣ ΑΥΖΩΤΗΣ Επιστ. υπεύθυνος Αιμοδυναμικού Τμήματος, Βιοκλινική GUIDELINES ON MYOCARDIAL
More informationI have no financial disclosures
Manpreet Singh MD I have no financial disclosures Exercise Treadmill Bicycle Functional capacity assessment Well validated prognostic value Ischemic assessment ECG changes ST segments Arrhythmias Hemodynamic
More informationAdvantages of PET Myocardial Imaging
Advantages of PET Myocardial Imaging Legal Disclaimers These materials were prepared in good faith by MITA as a service to the profession and are believed to be reliable based on current scientific literature.
More informationEvaluating Clinical Risk and Guiding management with SPECT Imaging
Evaluating Clinical Risk and Guiding management with SPECT Imaging Raffaele Giubbini Chair and Nuclear Medicine Unit University & Spedali Civili Brescia- Italy U.S. Congressional Budget Office. Technological
More informationFractional Flow Reserve: Basics, FAME 1, FAME 2. William F. Fearon, MD Associate Professor Stanford University Medical Center
Fractional Flow Reserve: Basics, FAME 1, FAME 2 William F. Fearon, MD Associate Professor Stanford University Medical Center Conflict of Interest Advisory Board for HeartFlow Research grant from St. Jude
More informationThe Value of Stress MRI in Evaluation of Myocardial Ischemia
The Value of Stress MRI in Evaluation of Myocardial Ischemia Dr. Saeed Al Sayari, MBBS, EBCR, MBA Department of Radiology and Nuclear Medicine Mafraq Hospital, Abu Dhabi United Arab Emirates Introduction
More informationMachine learning improves image analysis prognosis and diagnosis in cardiac imaging
Machine learning improves image analysis prognosis and diagnosis in cardiac imaging Some software described in this presentation is owned by Cedars-Sinai Medical Center, which receives or may receive royalties
More informationAdriano Duatti Department of Chemical and Pharmaceutical Sciences University of Ferrara Via L. Borsari, 46, Ferrara, Italy
Adriano Duatti Department of Chemical and Pharmaceutical Sciences University of Ferrara Via L. Borsari, 46, 44121 Ferrara, Italy dta@unife.it adriano.duatti@unife.it Summary Approved tracers for myocardial
More informationHybrid Imaging Improving Nuclear Cardiology Practice
Lippincott Williams & Wilkins, - Nuclear Medicine teaching File, 2009 Hybrid Imaging Improving Nuclear Cardiology Practice João V. Vitola, MD, PhD Cardiologist and Nuclear Medicine Physician Quanta Diagnostico
More informationNew Challenges in Nuclear Cardiology Practice
New Challenges in Nuclear Cardiology Practice Brian G. Abbott, MD, FACC, FASNC, FAHA President, ASNC 2016 Associate Professor of Medicine Warren Alpert Medical School of Brown University Director, Cardiovascular
More informationMPS and Calcium Score in asymptomatic patient F. Mut, J. Vitola
MPS and Calcium Score in asymptomatic patient F. Mut, J. Vitola Nuclear Medicine Service, Asociacion Española Montevideo, Uruguay Quanta Diagnostico Nuclear Curitiba, Brazil Clinical history Male 63 y.o.,
More informationA Light in the Dark: Cardiac MRI and Risk Mitigation. J. Ronald Mikolich MD Professor of Internal Medicine Northeast Ohio Medical University (NEOMED)
A Light in the Dark: Cardiac MRI and Risk Mitigation J. Ronald Mikolich MD Professor of Internal Medicine Northeast Ohio Medical University (NEOMED) Dr. Mikolich has NO financial disclosures relative to
More informationNuclear Cardiology Pierre-Yves MARIE Department of Nuclear Medicine CHU-Nancy, FRANCE.
Nuclear Cardiology Pierre-Yves MARIE Department of Nuclear Medicine CHU-Nancy, FRANCE. Nuclear Cardiology I - A remaining need of a functional information on myocardial perfusion II - The future: - combining
More informationTest in Subjects with Suspected CAD Anatomic Study is Better
Test in Subjects with Suspected CAD Anatomic Study is Better Hyuk Jae Chang MD, PhD Division of Cardiology Severance Cardiovascular Hospital Seoul Korea Functional Test Two Issues Accuracy of stress-tests
More informationCardiac Stress MRI: Detection of Ischemia. Disclosures: Dobutamine Stress MR. April 28, 2018
Cardiac MRI: Detection of Ischemia Cardiac MRI in Today s Clinical Practice Foundations of Cardiovascular Magnetic Resonance Daniel C. Lee, MD, MSc Assistant Professor of Medicine and Radiology Co-Director,
More informationCurrent Tracers. João V. Vitola, MD, PhD. Cardiologist and Nuclear Medicine Physician Quanta Diagnostico Nuclear Curitiba - Brazil
Current Tracers João V. Vitola, MD, PhD Cardiologist and Nuclear Medicine Physician Quanta Diagnostico Nuclear Curitiba - Brazil SPECT - Tracer Characteristics TC-99m tracers and protocols One or two day
More informationRole of Myocardial Perfusion Imaging in the Cardiac Evaluation of Aviators
Original Research Role of Myocardial Perfusion Imaging in the Cardiac Evaluation of Aviators Anil Kumar AVS *, Kumar PG +, Prakash MS # ABSTRACT In an attempt to provide more accurate and inclusive information
More informationImaging in Ischemic Heart Disease: Role of Cardiac MRI
Imaging in Ischemic Heart Disease: Role of Cardiac MRI Chiara Bucciarelli Ducci MD, PhD, FESC, FRCP Consultant Senior Lecturer Cardiologist Bristol Heart Institute, University of Bristol, UK Chair elect,
More informationNuclear Cardiology Cardiac Myocardial Perfusion with 82 Rb. Dominique Delbeke, MD, PhD Vanderbilt University Medical Center Nashville, TN
Nuclear Cardiology Cardiac Myocardial Perfusion with 82 Rb Dominique Delbeke, MD, PhD Vanderbilt University Medical Center Nashville, TN VUMC PET/CT conference 2009 82 Rb Cardiac Perfusion PET 82 Rb is
More informationEvaluation of Myocardial Viability: What Have We Learned from STICH? Professor of Medicine David Geffen School of Medicine at UCLA. Heart Failure (HF)
Evaluation of Myocardial Viability: What Have We Learned from STICH? Daniel S. Berman, MD Director, Cardiac Imaging Cedars-Sinai Heart Institute CSMC 2013 Professor of Medicine David Geffen School of Medicine
More informationMyocardial viability testing. What we knew and what is new
Myocardial viability testing. What we knew and what is new Dr B K S Sastry, MD, DM. CARE Hospitals, Hyderabad What is Viability Viability Dysfunctional myocardium subtended by diseased coronary arteries
More information63 yo woman with chest pain
63 yo woman with chest pain Coronary Microvascular Disease: Does It Exist? EA Amsterdam, MD Distinguished Professor Cardiology and Internal Medicine UC Davis School of Medicine and Medical Center Sacramento,
More informationA Light in the Dark: Cardiac MRI and Risk Mitigation. J. Ronald Mikolich MD Professor of Internal Medicine Northeast Ohio Medical University (NEOMED)
A Light in the Dark: Cardiac MRI and Risk Mitigation J. Ronald Mikolich MD Professor of Internal Medicine Northeast Ohio Medical University (NEOMED) Dr. Mikolich has NO financial disclosures relative to
More informationCardiac Imaging. Kimberly Delcour, DO, FACC. Mahi Ashwath, MD, FACC, FASE. Director, Cardiac CT. Director, Cardiac MRI
Cardiac Imaging Kimberly Delcour, DO, FACC Director, Cardiac CT Mahi Ashwath, MD, FACC, FASE Director, Cardiac MRI Cardiac Imaging Discuss the clinical applications of and indications for: Cardiac CT Nuclear
More informationState of the Art. Advances in Cardiovascular Imaging. ESC Congres Stockholm September 1, 2010 Frank E. Rademakers, MD, PhD, FESC
State of the Art Advances in Cardiovascular Imaging ESC Congres Stockholm September 1, 2010 Frank E. Rademakers, MD, PhD, FESC Coronary Artery Disease Content Patho Physiology Imaging requirements Economical
More informationEvidence for Everyone: Expanding the Reach of Health Technology Assessment 2016 CADTH Symposium, April 10-12, Shaw Centre, Ottawa
Dr. Ross Davies President Dr. Benjamin Chow Vice-President Dr. Jonathan Leipsic Secretary/Treasurer Office 222 Queen Street Suite 1403 Ottawa, ON K1P 5V9 www.ccs.ca/ nuclear_ct@ccs.ca Evidence for Everyone:
More informationImaging and heart failure
Imaging and heart failure Jeroen J Bax Dept of Cardiology Leiden Univ Medical Center The Netherlands Davos, feb 2013 Research grants: Medtronic, Biotronik, Boston, St Jude, BMS imaging, GE Healthcare,
More informationWhat the Cardiologist needs to know from Medical Images
What the Cardiologist needs to know from Medical Images Gerald Maurer Department of Cardiology Medical University of Vienna What kinds of Cardiologists Plumbers Electricians Photographers And then there
More informationFFR-CT Not Ready for Primetime
FFR-CT Not Ready for Primetime Leslee J. Shaw, PhD, MASNC, FACC, FAHA, FSCCT R. Bruce Logue Professor of Medicine Co-Director, Emory Clinical CV Research Institute Emory University School of Medicine Atlanta,
More informationMedical Policy An independent licensee of the Blue Cross Blue Shield Association
PET Scanning: Cardiac Applications Page 1 of 31 Medical Policy An independent licensee of the Blue Cross Blue Shield Association Title: Positron Emission Tomography (PET) Scanning: Cardiac Applications
More informationHybrid imaging of the heart
Pärnu (Estonia) Friday, October 10, 2014 8:00-8:30 a.m Hybrid imaging of the heart María José García Velloso Servicio de Medicina Nuclear Clínica Universidad de Navarra mjgarciave@unav.es Hibrid imaging
More informationCardiac Viability Testing A Clinical Perspective Annual Cardiac Imaging Symposium. Lisa M Mielniczuk MD FRCPC University of Ottawa Heart Institute
Cardiac Viability Testing A Clinical Perspective Annual Cardiac Imaging Symposium Lisa M Mielniczuk MD FRCPC University of Ottawa Heart Institute 62 year old male Anterior STEMI late presentation, occluded
More informationManagement of stable CAD FFR guided therapy: the new gold standard
Management of stable CAD FFR guided therapy: the new gold standard Suleiman Kharabsheh, MD Director; CCU, Telemetry and CHU Associate professor of Cardiology, Alfaisal Univ. KFHI - KFSHRC Should patients
More informationESC CONGRESS 2010 Stockholm, august 28 september 1, 2010
ESC CONGRESS 2010 Stockholm, august 28 september 1, 2010 CORONARY ARTERY DISEASE AND NUCLEAR IMAGING: AN UPDATE PERFUSION SCINTIGRAPHY IN HIGH-RISK ASYMPTOMATIC PATIENTS Pasquale Perrone Filardi Federico
More informationFFR-Guided PCI. 4 th Imaging and Physiology Summit October 29 th, 2010 Seoul, Korea. Stanford
4 th Imaging and Physiology Summit October 29 th, 2010 Seoul, Korea FFR-Guided PCI William F. Fearon, M.D. Associate Professor Division of Cardiovascular Medicine University Medical Center Disclosure Statement
More informationMedical Policy. MP Cardiac Applications of Positron Emission Tomography Scanning
Medical Policy BCBSA Ref. Policy: 6.01.20 Last Review: 09/19/2018 Effective Date: 09/19/2018 Section: Radiology Related Policies 6.01.51 Interim Positron Emission Tomography Scanning in Oncology to Detect
More informationConflict of Interest Disclosure
Challenges and Opportunities for SPECT & PET in 2013: Implementing Latest Acquisition and Processing Protocols Timothy M. Bateman M.D. Co-Director, Cardiovascular Radiologic Imaging Mid America Heart Institute
More informationmsv Stress dose (mci) Stress dose (MBq)
Supplemental Table 1. A Sample Weight Based Dosing for 99m Tc Sestamibi MPI Using a Dedicated Cardiac SPECT Scanner Weight range Rest (mci) Rest (MBq) msv Stress (mci) Stress (MBq) msv Total msv (rest
More informationRubidium-82 myocardial perfusion PET/CT
Rubidium- myocardial perfusion PET/CT A.M. Scholtens, MD 1 ; P.C. Barneveld, MD 2 Departments of Nuclear Medicine of 1 Meander Medical Center, Amersfoort, the Netherlands, and 2 Jeroen Bosch Hospital,
More informationPositron emission tomography and molecular imaging
Positron emission tomography and molecular imaging EHH, May, 2010 Juhani Knuuti Turku PET Centre University of Turku Turku, Finland Juhani.knuuti@utu.fi PET Imaging in Medicine MRI CT MRI PET US SPET MEG
More informationClinical case in perspective. Cases from Poland
Clinical case in perspective Cases from Poland Assoc. Prof. Jacek Legutko, MD, PhD President-Elect of the Association for Percutaneous Cardiovascular Interventions of the Polish Cardiac Society Institute
More informationCARDIAC PET PERFUSION IMAGING with RUBIDIUM-82
CARDIAC PET PERFUSION IMAGING with RUBIDIUM-82 Pr Denis AGOSTINI Président du Groupe de Cardiologie Nucléaire et IRM CHU Caen Bordeaux 2006 Cardiac Perfusion-Metabolism Mismatch with PET Cumulative Survival
More informationMaria Angela S. Cruz-Anacleto, MD
Maria Angela S. Cruz-Anacleto, MD 57/Female Menopausal Non-HTN, non-dm Hypothyroid (s/p RAI 1997) Levothyroxine 100 ug OD 5 Months PTA Chest discomfort Stress Echocardiography 5 Months PTA Chest discomfort
More information@02-126_Coronary_calcification.ppt. Professor Molecular and Medical Pharmacology
Assessment of Myocardial Viability Jamshid Maddahi, M.D., FACC, FASNC Professor Molecular and Medical Pharmacology (Nuclear Medicine) and Medicine (Cardiology) David Geffen School of Medicine at UCLA Director,
More informationCASE from South Korea
CASE from South Korea Bon-Kwon Koo, MD, PhD, Seoul, Korea Outpatient clinic of a non-interventional cardiologist F/56 Chief complaint: Angina with recent aggravation, CCS II~III Brief history: # Stroke
More informationQualitative and Quantitative Assessment of Perfusion
APCDE 2011 Qualitative and Quantitative Assessment of Perfusion Hyun Ju Yoon Chonnam National University Hospital Gwangju, Korea ISCHEMIC CASCADE Blood flow mismatch Perfusion defects on nuclear imaging,
More information海外研究留学報告 福島賢慈 東京女子医科大学 画像診断 核医学部 核医学地方会 2011 Jan
2011 Jan Maryland state (MD), USA Maryland state (MD), USA Baltimore city, MD Baltimore city, MD Myocardial Perfusion PET tracers PET Tracers Half life Production First Pass Extraction Kinetic Properties
More informationRadiologic Assessment of Myocardial Viability
November 2001 Radiologic Assessment of Myocardial Viability Joshua Moss, Harvard Medical School Year III Patient EF 66yo female with a 3-year history of intermittent chest pain previously relieved by sublingual
More informationRADIOTRACERS FOR MYOCARDIAL PERFUSION IMAGING
RADIOTRACERS FOR MYOCARDIAL PERFUSION IMAGING RAYMOND TAILLEFER, M.D. FRCP(c), ABNM DIRECTOR, DEPARTMENT OF NUCLEAR MEDICINE HOPITAL ST-JEAN-SUR-RICHELIEU Disclosures to Report: Grant Research Support:
More informationStress only Perfusion Imaging
European Society of Cardiology Annual meeting, 2010, Stockholm, Sweden Stress only Perfusion Imaging Oliver Gaemperli, MD Cardiovascular Center, University Hospital Zurich, Switzerland Male patient, 48
More informationCARDIAC MULTIMODALITY IMAGING: Informing better decisions - or just costly pictures?
CARDIAC MULTIMODALITY IMAGING: Informing better decisions - or just costly pictures? Jonathan P. Christiansen MBChB, MD, FRACP, FACC, FCSANZ Consultant Cardiologist, North Shore Hospital, Auckland Overview
More informationDebate Should we use FFR? I will say NO.
Debate Should we use FFR? I will say NO. Hyeon-Cheol Gwon Cardiac and Vascular Center Samsung Medical Center Sungkyunkwan University School of Medicine Dr. Hyeon-Cheol Gwon Research fund from Abbott Korea
More informationBenefit of Performing PCI Based on FFR
Benefit of Performing PCI Based on FFR William F. Fearon, MD Associate Professor Director, Interventional Cardiology Stanford University Medical Center Benefit of FFR-Guided PCI FFR-Guided PCI vs. Angiography-Guided
More informationJ. Schwitter, MD, FESC Section of Cardiology
J. Schwitter, MD, FESC Section of Cardiology CMR Center of the CHUV University Hospital Lausanne - CHUV Switzerland Centre de RM Cardiaque J. Schwitter, MD, FESC Section of Cardiology CMR Center of the
More informationDiagnostic Algorithms
Diagnostic Algorithms Udo Sechtem Robert-Bosch-Krankenhaus Stuttgart Germany Montalescot G et al. ESC Guideline on the Management of Stable Coronary Artery Disease Eur Heart J. 2013;34:2949-3003. European
More informationUpdate in Nuclear Cardiology: Patient-Centered Imaging Radiation Dose Reduction
Update in Nuclear Cardiology: Patient-Centered Imaging Radiation Dose Reduction E. Gordon DePuey, M.D. Icahn School of Medicine ant Mt. Sinai New York, NY Disclosures: Grant Support: Michael J. Fox Foundation
More information