Ambient Particulate Matter and Public Health
|
|
- Buck Hutchinson
- 6 years ago
- Views:
Transcription
1 Ambient Particulate Matter and Public Health PD Dr. Annette Peters GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
2 Ambient Particulate Matter (Example diesel particles) Fine Particulate Matter PM 10 : mass < 10 µm PM 2.5 : mass < 2.5 µm Ultrafine Particles UFP: number < 100 nm Daily average PM 10 in Leipzig, : 27 µg/m : 12 µg/m 3 Kreyling et al., GSF-IHB
3 Cohort study in North Rhine-Westphalia Women age were recruited between 1985 and 1994 Follow-up until 2003 Alive (N=4353) Dead (N=399) Modelling of exposure at residential address Gehring et al, Epidemiology, 2006
4 Adjusted Relative Risk of Mortality for IQR $ -Increase of Air Pollutants and Living Close to Busy Roads RR (95%CI) 2 education and smoking; PM 10 : 7 µg/m 3 ; PM 10 = 0.71*TSP $ IQR NO2=16 µg/m All Cause Cardiopulmonary Close to the busy road NO 2 (5 years) PM 10 (5 years) Gehring et al, Epidemiology, 2006
5 Who is susceptible and why? Inhalation of ambient particles Local Effects Inflammation Systemic Effects Acute phase proteins Cytokines Asthma attacks Bronchitis Ischemia Arrhythmia
6 Myocardial Infarction: Occlusion of the Coronary Arteries Healthy heart Occlusion Re-Perfusion
7 Women Health Study Cohort Study of 66,000 women across the US Recruited 1994 to 1998 Median Followup 6 years 1816 women had one or more fatal or nonfatal cardiovascular events Hazard ratio: 1.24 (1.09 to 1.41) per 10 µg/m 3 PM 2.5 Miller et al., NEJM 2007
8 HEAPSS: Follow-up of Myocardial Infarction Survivors City Period of Follow up Persons followed Augsburg Barcelona Helsinki Rome Stockholm *hospital admissions for acute angina, acute myocardial infarction, dysrhythmia or heart failure Cardiac readmissions* Klot et al. Circulation 2005
9 Air pollution and cardiac readmission in myocardial infarction survivors 1,20 1,15 Risk Ratio 1,10 1,05 1,00 0,95 0,90 PNC PM10 CO NO2 SO2 Klot et al. Circulation 2005
10 Particles and Myocardial Infarction HEAPSS-Follow-up Augsburg, Change [%] PM 10 Change [%] Particle number (estimated) Incident MI Secondary MI Death -20 Incident MI Secondary MI Death Klot et al. Circulation 2005
11 Increase in severity of the effects Health effects of particulate air pollution based on epidemiological studies CVD Mortality CVD Hospital admissions CVD Emergency room visits Changes in cardiac function (heart rate variability, repolarization), cardiac symptoms, pro-thrombotic status and increase in inflammatory markers in subjects with cardio-pulmonary disease Sub-clinical effects in healthy subjects Proportion of the population affected
12 Today: Loss in life expectancy Scenario for the year 2000: Loss in life expectancy attributable to anthropogenic PM2.5 (in months) Ammann et al. CAFE Scenario Analysis Report Nr. 6, June 2005 europa.eu.int/comm/environment/cafe/activities/pdf/cafe_scenario_report_6.pdf
13 Tomorrow: Reduced Impact of Particles? Scenario under current EU regulation for the year 2020: Loss in life expectancy attributable to anthropogenic PM2.5 (in months) Ammann et al. CAFE Scenario Analysis Report Nr. 6, June 2005 europa.eu.int/comm/environment/cafe/activities/pdf/cafe_scenario_report_6.pdf
14 Summary Fine ambient particles are associated with increased mortality predominately due to cardiovascular diseases Subjects with underlying disease are at higher risk for subsequent hospitalisation Further research is needed to guide the measures to most effectively protect public health in Europe
15 Thank you to Research Unit Health Effects of Particles : S. Breitner, I. Brüske-Hohlfeld, J. Cyrys, S. Greven, A. Henneberger, A. Ibald-Mulli, M. Marowsky-Köppl, M. Pitz, A. Peters, R. Rückerl, A. Schaffrath Rosario, M. Stölzel, W. Yue GSF-Institut of Epidemiology: J. Heinrich, H. E. Wichmann, G. Wölke GSF-Focus Network Aerosols and Health: J. Heyder, W. Kreyling, J. Schnelle-Kreis, H. Schulz, K. Wittmaack, R. Zimmermann KORA Coronary Event Registry: H. Löwel, M. Heier, I. Trentinglia, C. Winter, G. Orlik, P. Friedmann, G. Zimmermann, A. Hörmann, G. Kaup, C. Meisinger HEAPSS Study Group: F. Forastiere, Rome (Coordinator), T. Bellander, Stockholm, M. Kulmala, Helsinki, J. Pekkanen, Helsinki, A. Peters, Munich, J. Sunyer, Barcelona
16 Questions? München, Leopoldstr
Annette Peters. Research Needs for Aerosols and Health
Research Needs for Aerosols and Health Annette Peters Helmholtz Zentrum München, Institute of Epidemiology, Neuherberg, Germany Harvard School of Public Health, Department of Environmental Health, Boston,
More informationTemporal variability and health effects of air pollutants in epidemiological shortterm
Temporal variability and health effects of air pollutants in epidemiological shortterm studies Dr. Regina Pickford Beijing, 29.06.2016 Environmental Science Center, University of Augsburg, Augsburg, Germany
More informationHealth effects of (particulate) air pollution
Health effects of (particulate) air pollution Peter Hoet Ben Nemery Jan Emmerechts Katrien Luyts Ernesto Alfaro-Moreno Dorota Napierska K.U.Leuven Pneumology, Lung Toxicology Air pollution and Health Introduction
More informationAssociations of traffic related air pollutants with hospitalisation for first acute myocardial infarction: the HEAPSS study
844 ORIGINAL ARTICLE Associations of traffic related air pollutants with hospitalisation for first acute myocardial infarction: the HEAPSS study T Lanki, J Pekkanen, P Aalto, R Elosua, N Berglind, D D
More informationEpidemiological studies on health effects of ambient fine and ultrafine particles
Epidemiological studies on health effects of ambient fine and ultrafine particles Francesco Forastiere Department of Epidemiology, Rome E Health Authority, Rome, Italy Outline What are (urban air) ultrafines?
More informationAmbient Air Pollution Is Associated With Increased Risk of Hospital Cardiac Readmissions of Myocardial Infarction Survivors in Five European Cities
Ambient Air Pollution Is Associated With Increased Risk of Hospital Cardiac Readmissions of Myocardial Infarction Survivors in Five European Cities Stephanie von Klot, PhD; Annette Peters, PhD; Pasi Aalto,
More informationHealth Impact: Solid Conclusions and Volatile Questions
Health Impact: Solid Conclusions and Volatile Questions VERT Focus Event March 16th 2018 Loretta Müller, PhD, loretta.mueller@insel.ch Pediatric Pulmonology, University Children s Hospital Bern, Inselspital
More informationAmbient air pollution has been associated with increases in
ORIGINAL ARTICLE Ambient Air Pollution and Daily Mortality Among Survivors of Myocardial Infarction Niklas Berglind, a,b Tom Bellander, a,b Francesco Forastiere, c Stephanie von Klot, d Pasi Aalto, e Roberto
More informationt air pollution Peter Hoet Ben Nemery
Health effects of (particulate) t air pollution Peter Hoet Ben Nemery Tim Nawrot Jan Emmerechts Katrien Luyts Ernesto Alfaro Moreno Dorota Napierska K.U.Leuven Pneumology, Lung Toxicology Air pollution
More informationAir Quality: What an internist needs to know
Air Quality: What an internist needs to know Robert Paine, M.D. Pulmonary and Critical Care Medicine University of Utah School of Medicine Program for Air Quality, Health and Society February, 2017 October
More informationAir Pollution and Heart Health
Air Pollution and Heart Health Wayne E. Cascio, MD, FACC, FAHA Director, Environmental Public Health Division National Health and Environmental Effects Research Laboratory Disclosure of Conflicts of Interest
More informationAltered Cardiac Repolarization in Association with Air Pollution and Air Temperature among Myocardial Infarction Survivors
Research Altered Cardiac Repolarization in Association with Air Pollution and Air Temperature among Myocardial Infarction Survivors Regina Hampel, 1 Alexandra Schneider, 1 Irene Brüske, 1 Wojciech Zareba,
More informationHealth Effects of Ambient Air Pollution
Health Effects of Ambient Air Pollution Jennifer L. Peel, PhD, MPH jennifer.peel@colostate.edu Department of Environmental and Radiological Health Sciences Colorado State University Fort Collins, CO 5/18/2010
More informationCold periods, but also extreme heat, have been reported to
Epidemiology and Prevention Air Temperature and the Occurrence of Myocardial Infarction in Augsburg, Germany Kathrin Wolf, MSc; Alexandra Schneider, PhD; Susanne Breitner, PhD; Stephanie von Klot, PhD;
More informationCOMPARISON OF THE NUMBER OF ULTRA-FINE PARTICLES AND THE MASS OF FINE PARTICLES WITH RESPIRATORY SYMPTOMS IN ASTHMATICS
PII: S0003-4878(96)00128-7 Ann. occup. Hyg., Vol. 41, Supplement 1, pp. 19-23, 1997 1997 Published by Elsevier Science Ltd on behalf of BOHS Printed in Great Britain. All rights reserved 0003-4878/97 $17.00
More informationEffects of Black Carbon Exposure on Human Health
Department of Epidemiology & Public Health Effects of Black Carbon Exposure on Human Health Nino Künzli, MD PhD Deputy-Director Swiss Tropical and Public Health Institute Basel Head Departement of Epidemiology
More informationHealth Impact Assessment following HRAPIE
Health Impact Assessment following HRAPIE Mike Holland, EMRC mike.holland@emrc.co.uk TFIAM, Helsinki, May 2014 Health Risks of Air Pollution in Europe Led by WHO-Europe HRAPIE Informed analysis of the
More informationT-Wave Alternans, Air Pollution and Traffic in High-Risk Subjects
T-Wave Alternans, Air Pollution and Traffic in High-Risk Subjects Antonella Zanobetti, PhD a, *, Peter H. Stone, MD c, Frank E. Speizer, MD a,d, Joel D. Schwartz, PhD a, Brent A. Coull, PhD a,b, Helen
More informationIncreased asthma medication use in association with ambient fine and ultrafine particles
Eur Respir J 2002; 20: 691 702 DOI: 10.1183/09031936.02.01402001 Printed in UK all rights reserved Copyright #ERS Journals Ltd 2002 European Respiratory Journal ISSN 0903-1936 Increased asthma medication
More informationChristopher M. Carosino and Kent E. Pinkerton Center for Health and the Environment University of California, Davis
Christopher M. Carosino and Kent E. Pinkerton Center for Health and the Environment University of California, Davis Particulate Pollution in the San Joaquin Valley: Translating Science into Policy June
More informationUrban air pollution, and asthma and COPD hospital emergency room visits
See Editorial, page 574 c Tables S1, S2 and S3, figs S1 and S2, and supplementary data are published online only at http://thorax.bmj.com/content/ vol63/issue7 1 Environmental Epidemiology Unit, National
More informationExposure to elevated concentrations of ambient particulate
Coronary Heart Disease Ischemic Heart Disease Events Triggered by Short-Term Exposure to Fine Particulate Air Pollution C. Arden Pope III, PhD; Joseph B. Muhlestein, MD; Heidi T. May, MSPH; Dale G. Renlund,
More informationLong-term prognostic value of N-Terminal Pro-Brain Natriuretic Peptide (NT-proBNP) changes within one year in patients with coronary heart disease
Long-term prognostic value of N-Terminal Pro-Brain Natriuretic Peptide (NT-proBNP) changes within one year in patients with coronary heart disease D. Dallmeier 1, D. Rothenbacher 2, W. Koenig 1, H. Brenner
More informationEffects of Fine and Ultrafine Particles on Cardiorespiratory Symptoms in Elderly Subjects with Coronary Heart Disease
American Journal of Epidemiology Copyright 2003 by the Johns Hopkins Bloomberg School of Public Health All rights reserved Vol. 157, No. 7 Printed in U.S.A. DOI: 10.1093/aje/kwg021 Effects of Fine and
More informationAssessment of studies on the health risk from particle matter (PM <2.5) from car emissions in relation to other risks in the study population
Assessment of studies on the health risk from particle matter (PM
More informationCardiovascular Effects of Short-term Exposure to Air Pollution
Thesis for doctoral degree (Ph.D.) 2009 Thesis for doctoral degree (Ph.D.) 2009 Cardiovascular Effects of Short-term Exposure to Air Pollution Exploring potential pathways and susceptible subgroups Cardiovascular
More informationAir Pollution Exposure A Trigger for Myocardial Infarction?
Int. J. Environ. Res. Public Health 2010, 7, 1486-1499; doi:10.3390/ijerph7041486 OPEN ACCESS Article International Journal of Environmental Research and Public Health ISSN 1660-4601 www.mdpi.com/journal/ijerph
More informationDiesel Exhaust: Health Effects. Research Needs
Diesel Exhaust: Health Effects and Research Needs Eric Garshick, MD, MOH Assistant Professor of Medicine VA Boston Healthcare System Channing Laboratory, Brigham and Womens Hospital Harvard Medical School
More informationHealth impacts of diesel emissions
Health impacts of diesel emissions 13 June 2014 Christine Cowie www.smh.com.au Diesel exhaust particles DEP consist of a carbon core surrounded by trace metals, quinones, VOCs The solid particulate fraction
More informationConfounding Bias: Stratification
OUTLINE: Confounding- cont. Generalizability Reproducibility Effect modification Confounding Bias: Stratification Example 1: Association between place of residence & Chronic bronchitis Residence Chronic
More informationImpact of coronary atherosclerotic burden on clinical presentation and prognosis of patients with coronary artery disease
Impact of coronary atherosclerotic burden on clinical presentation and prognosis of patients with coronary artery disease Gjin Ndrepepa, Tomohisa Tada, Massimiliano Fusaro, Lamin King, Martin Hadamitzky,
More informationWhat are the Human Health Effects of Air Pollution?
What are the Human Health Effects of Air Pollution? Dr. Judy Guernsey Department of Community Health and Epidemiology Dalhousie University Nova Scotia Department of Environment and Labour Outdoor Air Quality
More informationARTICLE. A. Icks & T. Dickhaus & A. Hörmann & M. Heier & G. Giani & B. Kuch & C. Meisinger
Diabetologia (2009) 52:1836 1841 DOI 10.1007/s00125-009-1434-4 ARTICLE Differences in trends in estimated incidence of myocardial infarction in non-diabetic and diabetic people: Monitoring Trends and Determinants
More informationIncreases in Heart Rate during an Air Pollution Episode
American Journal of Epidemiology Copyright 1999 by The Johns Hopkins University School of Hygiene and Public Health All rights reserved Vol. 150, 10 Printed In U.S.A. Increases in Rate during an Air Pollution
More informationabstract conclusions Transient exposure to traffic may increase the risk of myocardial infarction in susceptible
The new england journal of medicine established in 1812 october 21, 2004 vol. 351 no. 17 Exposure to Traffic and the Onset of Myocardial Infarction Annette Peters, Ph.D., Stephanie von Klot, M.P.H., Margit
More informationEffects of air pollution on the incidence of myocardial infarction
See Featured editorial, page 1721 London School of Hygiene and Tropical Medicine, London, UK Correspondence to: Mr K Bhaskaran, London School of Hygiene and Tropical Medicine, M107, 49 51 Bedford Square,
More informationUpdate on Airborne Pollution and Blood Pressure
Update on Airborne Pollution and Blood Pressure Philippe van de Borne Hôpital Erasme Department of cardiology Brussels - Belgium 10h30-11h00 Friday 4 th March 2016 http://urgencesgrece.eu/fr http://urgencesgrece.eu/fr
More information22 nd ETH-Conference on Combustion Generated Nanoparticles June 18 21, 2018; Zürich, Switzerland. Wolfgang G. Kreyling
22 nd ETH-Conference on Combustion Generated Nanoparticles June 18 21, 2018; Zürich, Switzerland Engineered nanoparticles versus ambient ultrafine particles: how comparable are their interactions with
More informationParticulate Air Pollution and Risk of ST-Segment Depression During Repeated Submaximal Exercise Tests Among Subjects With Coronary Heart Disease
Particulate Air Pollution and Risk of ST-Segment Depression During Repeated Submaximal Exercise Tests Among Subjects With Coronary Heart Disease The Exposure and Risk Assessment for Fine and Ultrafine
More informationHealth Effects of Fine Particles. Bart Ostro, Ph.D., OEHHA Cal EPA
Health Effects of Fine Particles Bart Ostro, Ph.D., OEHHA Cal EPA PM10 and PM2.5: Size and Composition Fine Coarse Ultra Fine Sulfates Nitrates Ammonia Carbon Lead (HM) Organics Soil Dust Silica Salts
More informationHORMONE REPLACEMENT THERAPY
TRIALS OF HR RUTH (Barrett- Connor et al 29 ) JULY 2006 (Country) mean ± sd, range International trial 67.5 an Placebo component in 67.5 ± 6.7 women with Raloxifene or multiple 67.5 ± 6.6 risk factors
More informationA comprehensive review of European epidemiological studies on particulate matter exposure and health
A comprehensive review of European epidemiological studies on particulate matter exposure and health Prepared for CONCAWE s Special Task Force on Health Effects of Air Pollution (H/STF-27) by: E. Negri
More informationUFIPOLNET - Ultrafine particle size distributions in air pollution monitoring networks LIFE04 ENV/DE/000054
UFIPOLNET - Ultrafine particle size distributions in air pollution monitoring networks LIFE04 ENV/DE/000054 Project description Environmental issues Beneficiaries Administrative data Read more Contact
More informationComposition of PM 2.5 in the Urban Atmosphere Overall Episode PM 10>50μg/m 3
Why worry about PM 2.5 and Black Carbon? Dr Ian S Mudway MRC-PHE Centre for Environment & Health, King s College London Composition of PM 2.5 in the Urban Atmosphere Overall Episode PM 10>50μg/m 3 Yin
More informationPatient characteristics Intervention Comparison Length of followup
ISCHAEMIA TESTING CHAPTER TESTING FOR MYCOCARDIAL ISCHAEMIA VERSUS NOT TESTING FOR MYOCARDIAL ISCHAEMIA Ref ID: 4154 Reference Wienbergen H, Kai GA, Schiele R et al. Actual clinical practice exercise ing
More informationAsthma and air pollution: health effects and prevention
Asthma and air pollution: health effects and prevention FuyuenYip PhD, MPH Air Pollution and Respiratory Health Branch Division of Environmental Hazards and Health Effects National Center for Environmental
More informationGardner et al. Gardner et al. Particle and Fibre Toxicology 2014, 11:1
Ambient fine particulate air pollution triggers ST-elevation myocardial infarction, but not non-st elevation myocardial infarction: a case-crossover study Gardner et al. Gardner et al. Particle and Fibre
More informationUndetectable High Sensitivity Cardiac Troponin T Level in the Emergency Department and Risk of Myocardial Infarction
Undetectable High Sensitivity Cardiac Troponin T Level in the Emergency Department and Risk of Myocardial Infarction Nadia Bandstein, MD; Rickard Ljung, MD, PhD; Magnus Johansson, MD, PhD; Martin Holzmann,
More informationImproving air quality in North Carolina: beyond respiratory health effects
Improving air quality in North Carolina: beyond respiratory health effects Julia Kravchenko, MD, PHD Assistant Professor, Department of Surgery, Duke University School of Medicine October 27-28, 2016 Museum
More informationBUSINESS. Articles? Grades Midterm Review session
BUSINESS Articles? Grades Midterm Review session REVIEW Cardiac cells Myogenic cells Properties of contractile cells CONDUCTION SYSTEM OF THE HEART Conduction pathway SA node (pacemaker) atrial depolarization
More informationAir Pollution and Stroke Risk in the WHI. Gregory A. Wellenius, ScD Department of Epidemiology Brown University
Air Pollution and Stroke Risk in the WHI Gregory A. Wellenius, ScD Department of Epidemiology Brown University London Smog, 1952 In central London the visibility remained below 500 meters continuously
More informationAir pollution as noxious environmental factor in the development of cardiovascular disease
R E V I E W Air pollution as noxious environmental factor in the development of cardiovascular disease H.C. Hassing 1*, Th.B. Twickler 1, J.J.P. Kastelein 1, M.J.M. Cramer 2, F.R. Cassee 3 1 Department
More informationDECLARATION OF CONFLICT OF INTEREST
DECLARATION OF CONFLICT OF INTEREST Is there a mortality risk associated with aspirin use in heart failure? Results from a large community based cohort Margaret Bermingham, Mary-Kate Shanahan, Saki Miwa,
More informationStatins in lung disease
Statins in lung disease Associate Professor Robert Young BMedSc, MBChB, DPhil (Oxon), FRACP, FRCP University of Auckland, New Zealand Smoking and its complications Respiratory COPD Cardiovascular CAD Smoking
More informationThe Toxicology of Nanoparticles
The Toxicology of Nanoparticles Rodger Duffin ELEGI Laboratory, QMRI Edinburgh University Edinburgh Scotland Nanoparticle toxicology: the knowledge gap between accidental versus engineered nanoparticles
More informationAIR POLLUTION AND EMERGENCY DEPARTMENT VISITS FOR DEPRESSION IN EDMONTON, CANADA
International Journal of Occupational Medicine and Environmental Health 2007;20(3):241 245 DOI 10.2478/v10001-007-0024-2 AIR POLLUTION AND EMERGENCY DEPARTMENT VISITS FOR DEPRESSION IN EDMONTON, CANADA
More informationParticle number concentration at urban microenvironments
Particle number concentration at urban microenvironments G. Lonati, S. Ozgen, I. Luraghi, M. Giugliano DIIAR sez. Ambientale, Politecnico di Milano Piazza L. da Vinci, 32-20133 Milano (MI) The number concentration
More informationLogan Airport Health Study
Logan Airport Health Study Massachusetts Department of Public Health Bureau of Environmental Health M ay 2014 TABLE OF CONTENTS EXECUTIVE SUMMARY... 1 1 PROJECT OVERVIEW... 1 1.1 BACKGROUND... 1 1.2 GOALS
More informationGroup Against Smog and Pollution, Inc. We work to improve air quality to ensure human, environmental, and economic health.
Group Against Smog and Pollution, Inc. We work to improve air quality to ensure human, environmental, and economic health. Pittsburgh has made progress to improve air quality but More than 60% of days
More informationHealth effects of wood burning. Dr. M.E. Gerlofs-Nijland RIVM, The Netherlands
Health effects of wood burning Dr. M.E. Gerlofs-Nijland RIVM, The Netherlands 1 Outline Introduction wood smoke and particulate matter In vitro cell culture studies In vivo animal studies Comparison effects
More informationUS power plant carbon standards and clean air and health co-benefits
US power plant carbon standards and clean air and health co-benefits Emissions Modeling For each scenario, we used emissions output from ICF International s Integrated Planning Model (IPM) conducted by
More informationCauses of asthma and allergy in children. Göran Pershagen Institute of Environmental Medicine
Causes of asthma and allergy in children Göran Pershagen Institute of Environmental Medicine Determinants of childhood allergy / asthma Respiratory infections Allergens Micro-biological exposure Male sex
More informationSmoke gets in your lungs. Assoc Prof Peter Franklin University of Western Australia Environmental Health Directorate, EHD
Smoke gets in your lungs Assoc Prof Peter Franklin University of Western Australia Environmental Health Directorate, EHD Conflict of Interest Conflict of Interest I have an open fireplace Wood smoke is
More informationCardiovascular Effects of Mountaintop Mining Particulate Matter: Similarities to Shale Gas Development
Cardiovascular Effects of Mountaintop Mining Particulate Matter: Similarities to Shale Gas Development Travis L. Knuckles, Ph.D. Research Assistant Professor Occupational and Environmental Health Sciences
More informationThe study listed may include approved and non-approved uses, formulations or treatment regimens. The results reported in any single study may not
The study listed may include approved and non-approved uses, formulations or treatment regimens. The results reported in any single study may not reflect the overall results obtained on studies of a product.
More informationUltrafine Particle Health Effects. John R. Froines, Ph.D. Southern California Particle Center
Ultrafine Particle Health Effects John R. Froines, Ph.D. Southern California Particle Center Background PM2.5 standards based on evidence from Epi. studies consistent associations between outdoor PM concentrations
More informationLi Liu, Li-Ya Yu, Hui-Juan Mu, Li-Ying Xing, Yan-Xia Li, Guo-Wei Pan. Introduction
Review Article Shape of concentration-response curves between long-term particulate matter exposure and morbidities of chronic bronchitis: a review of epidemiological evidence Li Liu, Li-Ya Yu, Hui-Juan
More informationChoosing Study Outcomes that Reflect Cardiovascular Disease: From Biomarkers to Burden of Disease. Greg Wellenius Joel Kaufman
Choosing Study Outcomes that Reflect Cardiovascular Disease: From Biomarkers to Burden of Disease Greg Wellenius Joel Kaufman Framework for Choosing Subclinical Outcomes To Study What clinical outcomes
More informationParticle Pollution: It s s a Serious Concern. Template Presentation for Regions
Particle Pollution: It s s a Serious Concern Template Presentation for Regions What is particle pollution? The particles in particle pollution are so small, you can t see just one of them... An average
More informationDisclosures (2013 to the present)
What level and types of CV safety data acquisition should be considered to sufficiently characterize a drug s benefit/risk assessment by the end of Phase 3 development? Cardiac Safety Research Consortium
More informationLong-term exposure to air pollution and diabetes risk in Danish Nurse Cohort study
Long-term exposure to air pollution and diabetes risk in Danish Nurse Cohort study Anne Busch Hansen a, Line Ravnskjær b, Steffen Loft c, Klaus Kaae Andersen b, Elvira Bräuner d, Rikke Baastrup e, Claire
More information9th ETH Conference on CGP: 16. August 2005 Distribution and Clearance of Inhaled Ultrafine TiO 2 Particles in Rat Lungs
9th ETH Conference on CGP: 16. August 2005 Distribution and Clearance of Inhaled Ultrafine TiO 2 Particles in Rat Lungs Marianne Geiser University of Bern Airways & alveoli - rodent lung TiO 2 particle
More informationNitrogen dioxide and mortality: review and meta-analysis of long-term studies
ERJ Express. Published on February 20, 2014 as doi: 10.1183/09031936.00114713 REVIEW IN PRESS CORRECTED PROOF Nitrogen dioxide and mortality: review and meta-analysis of long-term studies Annunziata Faustini
More informationBottom Line. Scrubbers Diesel Particle Filters Catalysts for NOx and HC
Air Pollution Kills Joel Schwartz Departments of Environmental Health and Epidemiology, Harvard School of Public Health Director, Harvard Center for Risk Analysis Bottom Line Particulate Air Pollution
More informationThe Framingham Risk Score (FRS) is widely recommended
C-Reactive Protein Modulates Risk Prediction Based on the Framingham Score Implications for Future Risk Assessment: Results From a Large Cohort Study in Southern Germany Wolfgang Koenig, MD; Hannelore
More information1393/1/19 : Downloaded from jhad.kmu.ac.ir at 0: on Saturday February 16th 2019 SO 2 - :
1394/1/24 : 1393/1/19 : 1394 /3 / 1386-91 3 2 1 : 1386-91.. SO 2 - :. PM 10 CO O 3 NO 2. 12 Stata. :. 10. :. :..(1)..(1) -1-2 -3 Email:sadegh.ghazanfari@gmail.com : 02142933240 : : 1394 / 3 / 4 190 .....(4)
More informationSerum c-glutamyltransferase and risk of type 2 diabetes mellitus in men and women from the general population
Journal of Internal Medicine 2005; 258: 527 535 doi:10.1111/j.1365-2796.2005.01572.x Serum c-glutamyltransferase and risk of type 2 diabetes mellitus in men and women from the general population C. MEISINGER
More informationTable S1: Diagnosis and Procedure Codes Used to Ascertain Incident Hip Fracture
Technical Appendix Table S1: Diagnosis and Procedure Codes Used to Ascertain Incident Hip Fracture and Associated Surgical Treatment ICD 9 Code Descriptions Hip Fracture 820.XX Fracture neck of femur 821.XX
More informationAssociate Professor Gerry Devlin
Associate Professor Gerry Devlin Clinical Cardiologist and Interventional Cardiologist NZ Heart Foundation Hamilton 9:00-9:15 Secondary Prevention of IHD The Challenge of Secondary Prevention Associate
More informationGUIDANCE ON METHODOLOGY FOR ASSESSMENT OF FOREST FIRE INDUCED HEALTH EFFECTS
GUIDANCE ON METHODOLOGY FOR ASSESSMENT OF FOREST FIRE INDUCED HEALTH EFFECTS David M. Mannino Air Pollution and Respiratory Health Branch Division of Environmental Hazards and Health Effects National Center
More informationUniversity of Rochester EPA
R827354 University of Rochester EPA PM Center ULTRAFINE PARTICLES: CHARACTERIZATION, HEALTH EFFECTS AND PATHOPHYSIOLOGICAL MECHANISMS PROGRESS REPORT YEAR 4 (Project period: Years 6/99 5/2; 6/2 5/3) July,
More informationEffects of Exposure to Ultrafine Carbon Particles in Healthy Subjects and Subjects with Asthma
R E S E A R C H R E P O R T H E A L T H E F F E CTS IN STITUTE Number 126 December 2004 Effects of Exposure to Ultrafine Carbon Particles in Healthy Subjects and Subjects with Asthma Mark W Frampton, Mark
More informationJUPITER NEJM Poll. Panel Discussion: Literature that Should Have an Impact on our Practice: The JUPITER Study
Panel Discussion: Literature that Should Have an Impact on our Practice: The Study Kaiser COAST 11 th Annual Conference Maui, August 2009 Robert Blumberg, MD, FACC Ralph Brindis, MD, MPH, FACC Primary
More informationUsing DOACs in CAD Patients in Sinus Ryhthm Results of the ATLAS ACS 2, COMPASS and COMMANDER-HF Trials
Using DOACs in CAD Patients in Sinus Ryhthm Results of the ATLAS ACS 2, COMPASS and COMMANDER-HF Trials 19 th Annual San Diego Heart Failure Symposium for Primary Care Physicians January 11-12, 2019 La
More informationMost relevant sources of indoor particles in children s rooms and respiratory health effects of size-segregated particles
Air Pollution XX 457 Most relevant sources of indoor particles in children s rooms and respiratory health effects of size-segregated particles U. Franck 1, S. Röder 1, U. Schlink 1, M. Borte 2, O. Herbarth
More informationPrasugrel vs. Ticagrelor in ACS/PCI Which one to choose? V. Voudris MD FESC FACC 2 nd Cardiology Division Onassis Cardiac Surgery Center
Prasugrel vs. Ticagrelor in ACS/PCI Which one to choose? V. Voudris MD FESC FACC 2 nd Cardiology Division Onassis Cardiac Surgery Center Hospitalizations in the U.S. Due to ACS Acute Coronary Syndromes
More informationThis is a submitted version of a paper published in Epidemiology.
Umeå University This is a submitted version of a paper published in Epidemiology. Citation for the published paper: Oudin, A., Forsberg, B., Jakobsson, K. (2012) "Air pollution and stroke" Epidemiology,
More informationTransfusion triggers in acute coronary syndromes: The MINT trial
Transfusion triggers in acute coronary syndromes: The MINT trial Paul Hébert, MD MHSc(Epid) Physician-in-Chief, CHUM Professor, University of Montreal Objectives Review evidence on transfusion triggers
More informationJ. Michael Gaziano, M.D., M.P.H. European Society of Cardiology August 26 th 2018
ARRIVE (Aspirin to Reduce Risk of Initial Vascular Events): A Study to Assess the Efficacy and Safety of Aspirin in Patients at Moderate Risk of Cardiovascular Disease J. Michael Gaziano, M.D., M.P.H.
More informationCEEH Scientific Report No 7a
Centre for Energy, Environment and Health Report series ISSN 1904-7495 CEEH Scientific Report No 7a Description of the CEEH health effects model - selection of concentration-response functions Aarhus 2011
More informationBroomhill, Broomhall, Crookes, Crookesmoor & Crosspool 2008
,,, moor & 28 Air Quality Health Effects of Air Pollution Some Health Trends Neighbourhoods Information System (SNIS) 28BBCCCHealthAir 1 Prepared by Barbara Rimmington East End Quality of Life Initiative
More informationUndetectable High Sensitivity Cardiac Troponin T Level in the Emergency Department and Risk of Myocardial Infarction
Undetectable High Sensitivity Cardiac Troponin T Level in the Emergency Department and Risk of Myocardial Infarction Nadia Bandstein, MD; Rickard Ljung, MD, PhD; Magnus Johansson, MD, PhD; Martin Holzmann,
More informationThe Clinical Unmet need in the patient with Diabetes and ACS
The Clinical Unmet need in the patient with Diabetes and ACS Professor Kausik Ray (UK) BSc(hons), MBChB, MD, MPhil, FRCP (lon), FRCP (ed), FACC, FESC, FAHA Diabetes is a global public health challenge
More informationFrancesco Blasi Head Respiratory Medicine Section Cardio-Thoracic Department University of Milan, Italy
COPD EXACERBATIONS Francesco Blasi Head Respiratory Medicine Section Cardio-Thoracic Department University of Milan, Italy COPD OUTCOMES Cazzola M et al. ERJ 2008 COPD AND CARDIOVASCULAR DISEASE Cumulative
More informationTiming of angiography for high- risk ACS
Timing of angiography for high- risk ACS Christian Spaulding, MD, PhD, FESC, FACC Cardiology Department Cochin Hospital, Inserm U 970 Paris Descartes University Paris, France A very old story. The Interventional
More informationA Systematic Review of Relation between Long-term Exposure to Ambient Air Pollution and Chronic Disease: On-line Appendix
A Systematic Review of Relation between Long-term Exposure to Ambient Air Pollution and Chronic Disease: On-line Appendix Hong Chen, MSc 1 Mark S. Goldberg, PhD 1,2,3 Paul J. Villeneuve, PhD 4,5 1 Department
More informationEKG Competency for Agency
EKG Competency for Agency Name: Date: Agency: 1. The upper chambers of the heart are known as the: a. Atria b. Ventricles c. Mitral Valve d. Aortic Valve 2. The lower chambers of the heart are known as
More informationEpidemiological analyses throughout the world have
Increased Particulate Air Pollution and the Triggering of Myocardial Infarction Annette Peters, PhD; Douglas W. Dockery, ScD; James E. Muller, MD; Murray A. Mittleman, MD, DrPH Background Elevated concentrations
More information