Zdravila s farmakološkim učinkom na srcu
|
|
|
- Mervyn Gaines
- 6 years ago
- Views:
Transcription
1 Zdravila s farmakološkim učinkom na srcu Prof. dr. Mojca Kržan Inštitut za farmakologijo in eksperimentalno toksikologijo, Medicinska fakulteta, Univerza v Ljubljani
2 Zdravila s farmakološkim učinkom na srcu vpliv na porabo kisika in metabolizem vpliv na krčenje vpliv na prevajanje
3 Ishemična bolezen srca Stabilna angina pektoris Nestabilna angina pektoris Prinz-Metalova angina
4
5 Zdravila, za zdravljenje ishemične bolezni srca Zaviralci adrenergičnih receptorjev β Organski nitrati Zaviralci kalcijevih kanalov
6 Zaviralci adrenergičnih receptorjev β β-blockers continue to surprise us (Cruckshank, 2000)
7 Generacije zaviralcev adrenergičnih 1. generacija: neselektivni propranolol receptorjev β 2. generacija: selektivni za receptorje β1 atenolol, metoprolol, acebutolol, bisoprolol 3. Generacija: + vazodilatatorji β2 intrinzična simpatikomimetična aktivnost pindolol α1-adrenergična blokada labetalol, karvedilol Sproščanje NO: nebivolol
8
9
10 Neželeni učinki Spazem gladke mišice: bronhospazem, mrzle ekstremitete Pretirani učinki na srce: bradikardija, bloki prevajanja, pretiran negativni inotropni učinek Prehajnje skozi krvnomožgansko pregrado: nespečnost, depresija
11
12 Pozor Zaviralci adrenergičnih receptorjev β Regulatorno zvečanje števila receptorjev Postopna prekinitev zdravljenja
13 Organski nitrati As is often true in matters of the heart, absence (nitrate-free intervals) makes the heart grow fonder (more nitrate responsiveness) (Opie, 1991)
14
15 Organski nitrati Nitroglicerin Isosorbid dinitrat Pentaeritritol tetranitrat Eritritil tetranitrat
16
17 Neželeni učinki glavobol hipotenzija bradikardija / tahikardija methemoglobinemija rezistenca na heparin toleranca
18 Toleranca ob jemanju organskih nitratov Neznan mehanizem Kako rešujemo: 12 ur na dan brez organskih nitratov
19 Zaviralci kalcijevih kanalov
20
21 Zaviralci kalcijevih kanalov Verapamil, diltiazem Dihidropiridinski: nikardipin, nifedipin, amlodipin, felodipin, isradipin, nitrendipin, nisoldipin
22
23
24 Neželeni učinki Vsi glavobol, edemi, naval krvi v glavo, omotičnost, možna srčna odpoved Verapamil konstipacija
25 Povzetek
26 Farmakološko zdravljenje srčnega popuščanja
27 Akutno popuščanje srca Kronično popuščanje srca
28 Cilji zdravljenja srčnega popuščanja Olajšanje simptomov Upočasnitev bolezni Izboljšanje preživetja
29 Zdravila z akutnim inotropnim učinkom simpatikomimetiki in druga zdravila Dobutamin β1 >β2 > α Dopamin β1 (β2), α, D1, D2 Adrenalin β1 > α > β2 Noradrenalin β1 = β2 > α Levosimendan
30
31 1. Hemodinamske spremembe simptomi 2. Nevrohumoralna aktivacija 3. Remodeliranje prekata Napredovanje bolezni
32 Zdravljenje kroničnega srčnega popuščanja ACE inhibitorji Zaviralci adrenergičnih receptorjev β Diuretiki Inotropna zdravila Neposredni vazodilatatorji Antagonisti aldosterona
33 Učinki zdravljenja kroničnega srčnega popuščanja Zmanjšanje obremenitve miokarda Zmanjšanje volumna zunajcelične tekočine Izboljšana kontraktilnost srca Upočasnitev preoblikovanja/remodeliranja
34 Zaviralci ACE The benefits of ACEI exceed our expectations. (Francis, 2000)
35 Generacije inhibitorjev ACE razred I kaptopril razred II prozdravila benazepril, enalapril, fosinopril, kvinapril razred III vodotopni lisinopril
36 Mehanizem delovanja ACE inhibitorjev
37 Neželeni učinki inhibitorjev ACE Kašelj Ortostatska hipotenzija Reverzibilna ledvična odpoved Angioedem Hiperkaliemija Embriopatije Nevtropenija /agranulocitoza (visoki odmerki) Izguba okusa
38 Antagonisti receptorjev za angiotenzin- II primeri: losartan, irbesartan, telmisartan, valsartan Prednosti: ni učinkov, ki jih posreduje bradikinin (npr. kašelj), padec holesterola v serumu Pomanjkljivosti: ni vazodilatacije v ledvicah, ni zaščite endotelija.
39 Digoksin Digitalis is effective, but is it safe? Marcus 1993
40
41 Kardiotonični glikozidi mehanizem delovanja
42 Farmakokinetika digoksina Absorpcija 75% Inaktivacija prek bakterij v GITu Terepevtska konc. 1-2 ng/ml, zdaj ng/ml Veže se na receptorje v srcu in skeletni mišici Prehaja v CŽS Večina se ga izloči nespremenjenega z urinom, 30% prek jeter Kronična odpoved ledvic manjši Vd Izguba telesne mase manjša vezava na skeletne mišice
43 Stanja, ki vplivajo na delovanje digoksina Povečajo Hipokaliemija Hipomagneziemija Hiperkalcemija Hipoksemija hipotiroidizem Zmanjšajo Hiperkaliemija Hipokalcemija Hipertiroidizem
44
45 Neželeni učinki digitalisa GIT: anoreksija, navzeja, bruhanje, diareja CŽS: utrujenost, zmedenost, bolečine po obrazu, nespečnost, vertigo, motnje vida Srce: palpitacije, aritmije, sinkopa
46 Povzetek
ASEBP and ARTA TARP Drugs and Reference Price by Categories
ASEBP Pantoprazole Sodium 40 mg (generic) $0.2016 ASEBP Dexlansoprazole 30 mg Dexlansoprazole 60 mg Esomeprazole 10 mg Esomeprazole 20 mg Esomeprazole 40 mg Lansoprazole 15 mg Lansoprazole 30 mg Omeprazole
Introductory Clinical Pharmacology Chapter 41 Antihypertensive Drugs
Introductory Clinical Pharmacology Chapter 41 Antihypertensive Drugs Blood Pressure Normal = sys
Factors Involved in Poor Control of Risk Factors
Factors Involved in Poor Control of Risk Factors Patient compliance Clinical inertia Health Care System structure 14781 M Limitations of Formal Studies Selection of patients Recruitment and follow-up alter
Zdravila, ki se uporabljajo pri pešanju srca
Zdravila, ki se uporabljajo pri pešanju srca Prof. Lovro Stanovnik Pešanje srca (PS) Nesposobnost črpanja krvi v skladu s potrebami tkiv (ob normalnem polnilnem tlaku) Slabše e prenašanje anje napora Relationship
Cardiac Medications At A Glance
Cardiac Medications At A Glance 1) Anticoagulants (Also known as Blood Thinners.) Dalteparin (Fragmin), Danaparoid (Orgaran) Enoxaparin (Lovenox) Heparin (various) Tinzaparin (Innohep) Warfarin (Coumadin)
Antihypertensive Agents
Antihypertensive Agents Southern California University of Health Sciences Physician Assistant Program Management and Treatment of Hypertension April 7, 08, presented by Ezra Levy, Pharm.D! Usual Dose,
DRUG CLASSIFICATION. Prevention of Cardiovascular Disease
Generic Preventive Care/ Safe Harbor Drug Program List Preventive care/safe harbor drugs are drugs that can help keep you from developing a health condition or related complications of a health condition.
ACEBUTOLOL HCL 100MG TABLET GENERIC BETA BLOCKERS ALISKIREN 150MG TABLET RASILAZ RENIN INHIBITOR
S/N ME OF MEDICATIONS BRANDED/GENERIC DRUG CLASS * UNIT PRICE RANGE (SGD$) 1 ACEBUTOLOL HCL 100MG CAPSULE SECTRAL BETA BLOCKERS 0.50 2 ACEBUTOLOL HCL 100MG TABLET GENERIC BETA BLOCKERS 0.33 3 ALISKIREN
Antihypertensive Agents Part-2. Assistant Prof. Dr. Najlaa Saadi PhD Pharmacology Faculty of Pharmacy University of Philadelphia
Antihypertensive Agents Part-2 Assistant Prof. Dr. Najlaa Saadi PhD Pharmacology Faculty of Pharmacy University of Philadelphia Agents that block production or action of angiotensin Angiotensin-converting
Select Preventive Prescription Drugs Jan. 1, 2018
Select Preventive Prescription Drugs Jan. 1, 2018 In addition to a healthy lifestyle, preventive medications can help you avoid some illnesses and conditions. Zimmer Biomet's medical options Value HSA,
PassAssured's Pharmacy Technician Training Systems. Medication Review. Cardiovascular Drugs. Pharmacy Technician Training Systems Passassured, LLC
Medication Review Cardiovascular Drugs Pharmacy Technician Training Systems Passassured, LLC p1 Medication Review, Cardiovascular Drugs Click Here for Glossary Index! Click Here to Print Topic Help File
Chapter 2 ~ Cardiovascular system
Chapter 2 ~ Cardiovascular System: General Section 1 of 6 Chapter 2 ~ Cardiovascular system 2.1 Positive inotropic drugs 2.1.1 Cardiac glycosides DIGOXIN 2.2 Diuretics Elixir 50micrograms in 1ml Injection
Generic Preventive Care/ Safe Harbor Drug Program List
Preventive care/safe harbor drugs are drugs that can help keep you from developing a health condition or related complications of a health condition. The Generic Preventive Care/Safe Harbor Drug Program
Chapter / Section / Drug
2 Cardiovascular System 2.1 Positive inotropic drugs Digoxin Digoxin specific antibody ( DigiFab ) 2.2 Diuretics 2.2.1 Thiazides and related diuretics Indapamide (1 st Line) Bendroflumethiazide Metolazone
ISMJ International SportMed Journal
32 ISMJ International SportMed Journal FIMS Position Statement Antihypertensive medications and exercise Associate Professor Wayne Derman UCT/MRC Research Unit for Exercise Science and Sports Medicine,
12.5mg, 25mg, 50mg. 25mg, 50mg. 2.5mg, 5mg, 10mg. 5mg, 10mg, 20mg, 100mg. 25mg. -- $2.81 Acetazolamide (IR, 125mg, 250mg, 500mg (ER)
MEDICATION COVERAGE POLICY PHARMACY AND THERAPEUTICS ADVISORY COMMITTEE POLICY: Blood Pressure P&T DATE: 5/9/2017 THERAPEUTIC CLASS: Cardiovascular Disorders REVIEW HISTORY: 9/15, 2/13, 2/08, 5/07 LOB
APPENDIX D: PHARMACOTYHERAPY EVIDENCE
Página 1 de 7 APPENDIX D: PHARMACOTYHERAPY EVIDENCE Table D1. Outcome Trials of Antihypertensive Agents Study Drug Regimen N Duration Primary Outcomes Remarks Antihypertensive Therapy vs Placebo SHEP 1991
Farmakologija noradrenergičnega sistema
Inštitut za farmakologijo in eksperimentalno toksikologijo, Medicinska fakulteta, Univerza v Ljubljani Farmakologija noradrenergičnega sistema Prof. dr. Lovro Stanovnik Inštitut za farmakologijo in eksperimentalno
Brookings Roundtable on Active Medical Product Surveillance:
2012, The Brookings Institution Brookings Roundtable on Active Medical Product Surveillance: Findings from a Mini-Sentinel Medical Product Assessment Marsha Reichman, U.S. Food and Drug Administration
ANTIHYPERTENSIVES. Assoc. Prof. Bilgen Başgut
ANTIHYPERTENSIVES Assoc. Prof. Bilgen Başgut Hypertension Hypertension is a condition in which the blood pressure is persistently higher than normal Hypertension > 140 mmhg > 90 mmhg Systolic Blood Pressure
8/19/2016. No Conflicts. I struggled with everything cardiac in nursing school.
Cindy Weston, DNP, RN, CCRN, CNS CC, FNP BC Assistant Professor, Texas A&M Health Science Center College of Nursing Describe and define epidemiology and pathophysiology of hypertension Differentiate JNC8
Hypertension (JNC-8)
Hypertension (JNC-8) Southern California University of Health Sciences Physician Assistant Program Management and Treatment of Hypertension April 17, 2018, presented by Ezra Levy, Pharm.D.! The 8 th Joint
Antihypertensive Agents
Antihypertensive Agents Öner Süzer www.onersuzer.com osuzer@istanbul.edu.tr Last update: 13.11.2009 1 Süzer Farmakoloji 3. Baskı 2005 2 1 Süzer Farmakoloji 3. Baskı 2005 3 Süzer Farmakoloji 3. Baskı 2005
Prof. Ramzy H. El Mawardy. Cairo Egypt 2009
Prof. Ramzy H. El Mawardy Ain Shams University Cairo Egypt 2009 Burden of HRN is increasing worldwide = 7 billion individuals. BP control is still poor = 60.70%. Global risk assessment is essential in
Cilazapril to lisinopril dose conversion
Cilazapril to lisinopril dose conversion The Borg System is 100 % Cilazapril to lisinopril dose conversion COMPARISON OF ANGIOTENSIN CONVERTING ENZYME (ACE). INHIBITORS. Drug. Approximate. Dose. Equivalence.
Generic Drugs: What does equal really mean? Dr. Peter J. Lin Director Primary Care Initiatives Canadian Heart Research Centre
Generic Drugs: What does equal really mean? Dr. Peter J. Lin Director Primary Care Initiatives Canadian Heart Research Centre Copyright 2017 by Sea Courses Inc. All rights reserved. No part of this document
Hypertension is also an important risk factor in the development of chronic kidney disease and heart failure.
Hypertension Hypertension Hypertension is defined as either a sustained systolic blood pressure of greater than 140 mm Hg or a sustained diastolic blood pressure of greater than 90 mm Hg. Hypertension
Ambetter 90-Day-Supply Maintenance Drug List
Ambetter 90-Day-Supply Maintenance Drug List What is the Ambetter 90-Day-Supply Maintenance Drug List? Ambetter 90-Day-Supply Maintenance Drug List is a list of maintenance medications that are available
12.5mg, 25mg, 50mg. 25mg, 50mg. 250mg, 500mg, 250mg/5ml. 2.5mg, 5mg, 10mg. 5mg, 10mg, 20mg, 100mg. 25mg
MEDICATION COVERAGE POLICY PHARMACY AND THERAPEUTICS ADVISORY COMMITTEE POLICY: Blood Pressure P&T DATE: 9/11/2018 THERAPEUTIC CLASS: Cardiovascular Disorders REVIEW HISTORY: 5/17, 9/15, 2/13, 2/08, LOB
Value-Based Drug List for ABCs of Diabetes
Effective January 1, 2019 Value-Based Drug List for ABCs of Diabetes PCPS provides a Value-Based Benefit Design (VBD) to qualified participants in the ABCs of Diabetes. This means you will have lower out-of-pocket
Codes for a Medicare claims-based model to predict LVEF class- User Guide
Description and citation: This guide accompanies our manuscript [Desai RJ, Lin KJ, Patorno E, et al. Development and Preliminary Validation of a Medicare Claims Based Model to Predict Left Ventricular
2019 Preventive Drug List
2019 Preventive Drug List Managing your health with preventive medications Your pharmacy benefit plan includes special coverage for generic preventive medications. These medications help protect against
Additional Standard Generics HSA Preventive Drug List Effective January 1, 2019
Additional Standard Generics HSA Preventive Drug List Effective January 1, 2019 Employers can elect to include an additional generic HSA Preventive Drug coverage feature with your prescription benefit
Chapter 2 - Cardiovascular System. Primary Care Prescribing Formulary - Preferred Drug Choices
Chapter 2 - Cardiovascular System Primary Care Prescribing Formulary - Preferred Drug Choices Drug group Drug choice Comments/notes Cardiac glycosides Thiazide diuretics Loop diuretics Aldosterone antagonist
2019 Preventive medications and your plan
2019 Preventive medications and your plan Managing your health with preventive medications Your pharmacy benefit plan includes special coverage for generic preventive medications. These medications help
The ADDITION Study: A study about screening for diabetes. Screening Case Report Form
ADDITION Study, Leicester Participant Identification Label: Date: / / The ADDITION Study: A study about screening for diabetes Screening Case Report Form You will need to have the following things done
Section 3, Lecture 2
59-291 Section 3, Lecture 2 Diuretics: -increase in Na + excretion (naturesis) Thiazide and Related diuretics -decreased PVR due to decreases muscle contraction -an economical and effective treatment -protect
Hypertension Management - Summary
Who should have blood pressure assessed? Hypertension Management - Summary All patients over the age of 40 years, every 1-3 years in order to determine their cardiovascular risk (ie. Framingham Risk Score)
New classification of HT Systolic Diastolic Normal <120 <80 Prehypertension Stage1HT Stage 2 HT >160 or >100
Hypertension 1 Definition Hypertension can be defined as a condition where blood pressure is elevated to an extent that clinical benefit is obtained from blood pressure lowering. it is an important risk
CARDIAC IMAGING QUESTIONNAIRE
Date of test: / / Month day year Last name First name Middle initial Street address City State Zip code Home phone ( ) - Work phone ( ) - Cell Phone ( ) - Email: Age: Demographics: What is your ethnicity?
By Prof. Khaled El-Rabat
What is The Optimum? By Prof. Khaled El-Rabat Professor of Cardiology - Benha Faculty of Medicine HT. Introduction Despite major worldwide efforts over recent decades directed at diagnosing and treating
Supplementary appendix
Supplementary appendix This appendix formed part of the original submission and has been peer reviewed. We post it as supplied by the authors. Supplement to: Xie X, Atkins E, Lv J, et al. Effects of intensive
DROGAS PARA HIPERTENSION ARTERIAL JONATHAN POVEDA FERNANDEZ HSJD / 2013 FACC/FSCAI/FESC
DROGAS PARA HIPERTENSION ARTERIAL JONATHAN POVEDA FERNANDEZ HSJD / 2013 FACC/FSCAI/FESC Pharmacotherapy of HTN Rationale for reducing arterial pressure Reduce cardiac output Reduce heart rate Reduce stroke
Annual Review of Antihypertensives - Fiscal Year 2009
Annual Review of Antihypertensives - Fiscal Year 2009 Oklahoma HealthCare Authority April 2010 Current Prior Authorization Criteria There are 7 categories of antihypertensive medications currently included
5mg/5mL Liquid 25mg Tablets 50mg Tablets 100mg Tablets 50mg/5mL Suspension Special standardise strength 25mg Tablets
Chapter 2- Cardiovascular Category Drug name Strength / dose / form BCU 2.1 Positive Inotropic drugs 2.1.1 Cardiac Digoxin 62.5 microgram Tablets Glycosides 125 microgram Tablets 250 microgram Tablets
Drug Therapy of Heart Failure. Munir Gharaibeh, MD, PhD, MHPE Faculty of Medicine, The University of Jordan November, 2014
Drug Therapy of Heart Failure Munir Gharaibeh, MD, PhD, MHPE Faculty of Medicine, The University of Jordan November, 2014 Drug Therapy of Heart Failure Definition of Heart Failure Causes Classifications
Medications and Falls Part 1
Medications and Falls Part 1 Introduction with General Principles and Risk Evaluation for Cardiovascular Medications Dennis J Chapron Medication Safety Pharmacist Saint Francis Hospital and Medical Center
Some Facts. Medications and Falls Part 1. Centers for Disease Control (CDC) Falls Statistics for Older Adults ( 65yrs) 11/27/2018
Medications and Falls Part 1 Introduction with General Principles and Risk Evaluation for Cardiovascular Medications Dennis J Chapron reports no real or potential conflicts of interest relevant to this
Review Protocol Patient information
Review Protocol Patient information What are information needs of patients with stable angina regarding their condition and its management? Adults with a diagnosis of stable angina including people with
Management of Hypertension
Clinical Practice Guidelines Management of Hypertension Definition and classification of blood pressure levels (mmhg) Category Systolic Diastolic Normal
What in the World is Functional Medicine?
What in the World is Functional Medicine? An Introduction to a Systems Based Approach of Chronic Disease Meneah R Haworth, FNP-C Disclosure v I am a student of the Institute for Functional Medicine. They
Zdravljenje pridobljene hemofilije. Irena Preložnik Zupan
Zdravljenje pridobljene hemofilije Irena Preložnik Zupan CILJI 1. Definicija, klinična slika, diagnoza 2. Zdravljenje zdravljenje akutnih krvavitev odstranjevanje inhibitorjev Pridobljeni inhibitorji koagulacije
Clinical Policy: Ranolazine (Ranexa) Reference Number: CP.PMN.34 Effective Date: Last Review Date: 02.19
Clinical Policy: (Ranexa) Reference Number: CP.PMN.34 Effective Date: 08.01.09 Last Review Date: 02.19 Line of Business: Medicaid Revision Log See Important Reminder at the end of this policy for important
Uvod v farmakologijo perifernega živčevja
Uvod v farmakologijo perifernega živčevja Prof. Lovro Stanovnik Prenos v živčevju Kriteriji, da je učinkovita endogena snov proglašena za mediator Dokaz, je snov in encimi za njeno sintezo prisotna na
HypertensionTreatment Guidelines. Michaelene Urban APRN, MSN, ACNS-BC, ANP-BC
HypertensionTreatment Guidelines Michaelene Urban APRN, MSN, ACNS-BC, ANP-BC Objectives: Review the definition of the different stages of HTN. Review the current guidelines for treatment of HTN. Provided
Information in these slides is used with permission from St. Mary s Cardiac Rehab
Information in these slides is used with permission from St. Mary s Cardiac Rehab Prescription Pointers Heart Medications Questions!! 2-4% of patients who visit ER s have experienced a medication misadventure
Medicines for high blood pressure
Patient Information: Medicines Medicines for high blood pressure Health & care information you can trust The Information Standard Certified Member Working together for better patient information What is
ija 3 m Adrenergični č sistem 2 adrenergični agonisti/antagonisti č ska ke acevt Farm Izr. Izr prof pr. of dr. dr Marko Mark o Anderluh 4.
acevts ska kem mija 3 Farm Adrenergični sistem 2 adrenergični agonisti/antagonisti Izr. prof. dr. Marko Anderluh 4. april 2013 adrenergični agonisti Agonisti 2 aktivirajo presinaptične receptorje in zavrejo
Antihypertensive Drugs. Munir Gharaibeh, MD, PhD, MHPE Faculty of Medicine, The University of Jordan November, 2014
Antihypertensive Drugs Munir Gharaibeh, MD, PhD, MHPE Faculty of Medicine, The University of Jordan November, 2014 Antihypertensive Drugs What is Hypertension: A common, incurable, persistent, but usually
PHARMACOLOGIC STRATEGIES
RISK FACTOR REDUCTION: PHARMACOLOGIC AND NONPHARMACOLOGIC STRATEGIES George L. Bakris, MD* ABSTRACT The renin-angiotensin-aldosterone system is one of the systems that serve as a fulcrum upon which blood
Beta-blockers. Atenolol. Propranolol. Bisoprolol. Metoprolol. Labetalol. Carvedilol.
Drugs of CVS Beta-blockers Atenolol. Propranolol. Bisoprolol. Metoprolol. Labetalol. Carvedilol. Atenolol.cardioselective Propranolol, nonselective Bisoprolol, cardioselective Metoprolol Carvedilol, alpha
Preventing and Managing High Blood Pressure
MINTO PREVENTION & REHABILITATION CENTRE CENTRE DE PREVENTION ET DE READAPTATION MINTO Preventing and Managing High Blood Pressure About This Kit Fortunately, high blood pressure is easily detected and
sympatholytics sympatholytics sympatholytics
sympatholytics sympatholytics sympatholytics CNS-ACTING SYMPATHOPLEGICS Sympathetic brain signals Doesn t affect baroreceptor reflex (no orthostatic hypotension) Methyldopa α-methylne crosses BBB (+) α-adrenoreceptors
HYPERTENSION. Dr. Ahmed A. Elberry, MBBCH, MSc, MD Assistant Professor of Clinical Pharmacy Faculty of pharmacy, KAU. Hypertension
HYPERTENSION Dr. Ahmed A. Elberry, MBBCH, MSc, MD Assistant Professor of Clinical Pharmacy Faculty of pharmacy, KAU 1 Hypertension It is a sustained of arterial bl. pr. 140/90 Causes: 1. 2. 1ry: Essential
Antihypertensive Drugs. Munir Gharaibeh, MD, PhD, MHPE School of Medicine, The University of Jordan October, 2017
Antihypertensive Drugs Munir Gharaibeh, MD, PhD, MHPE School of Medicine, The University of Jordan October, 2017 Antihypertensive Drugs What is Hypertension? A common, incurable, persistent, but usually
University of Al Qadisiyah College of Pharmacy Dr. Bassim I Mohammad, MBChB, MSc, Ph.D
University of Al Qadisiyah College of Pharmacy Dr. Bassim I Mohammad, MBChB, MSc, Ph.D Cardiovascular Pharmacology 1. Antihypertensives 2. Antianginal 3. Drugs for HF 4. Antiarrythemics 5. Drugs for Hyperlipoproteniemia
Clinical Teach-Back Cards
Clinical Teach-Back Cards The Medicare Quality Improvement Organization for Texas TMF Health Quality Institute focuses on improving lives by improving the quality of health care through contracts with
ANTIHYPERTENSIVE AGENTS AND VASODILATORS. Lecture 5
ANTIHYPERTENSIVE AGENTS AND VASODILATORS Lecture 5 Hypertension Blood pressure BP = CO x PVR n Interaction between autonomic nervous system, cardiovascular system and renal system Normal: 110/70 Prehypertension
Drug Regimen Optimization
Texas Prior Authorization Program Clinical Criteria Drug/Drug Class Clinical Criteria Information Included in this Document Excluding Valsartan / Ramipril Prior authorization criteria logic: a description
Conversion of losartan to lisinopril
Cari untuk: Cari Cari Conversion of losartan to lisinopril Dania Alsammarae, Strategy Director and co-founder of Anglo Arabian Healthcare speaks with Neil Halligan of Arabian Business on what it takes
Clinical Teach-Back Cards
Clinical Teach-Back Cards The Quality Innovation Network - Quality Improvement Organization (QIN-QIO) for Delaware, Louisiana, New Jersey, Pennsylvania and West Virginia The people at Quality Insights
Adapted d from Federation of Health Regulatory Colleges of Ontario Template Last Updated September 18, 2017
Insert Logo or Org Name Here Primary Care Medical Directive for Hypertension Management Adapted d from Federation of Health Regulatory Colleges of Ontario Template Last Updated September 18, 2017 Title:
Farmakoterapija koronarne bolezni
Farmakoterapija koronarne bolezni Jurij Fürst F Zavod za zdravstveno zavarovanje Slovenije Oddelek za zdravila Univerza v Ljubljani Fakulteta za farmacijo Teme epidemiologija dejavniki tveganja za aterosklerozo
Supplementary Appendix
Supplementary Appendix Should Diabetes Mellitus be a Compelling Indication for Renin Angiotensin System Blockers? Insights from a Systematic Review and Meta-Analysis of Randomized Trials Sripal Bangalore,
Treatment of Essential Hypertension
2016 edition by Mark A. Simmons, PhD Department of Pharmaceutical Sciences School of Pharmacy University of Maryland Eastern Shore Originally developed by Hugh J. Burford, PhD, FCP Department of Pharmacology
DECLARATION OF CONFLICT OF INTEREST
DECLARATION OF CONFLICT OF INTEREST Third generation beta-blockers in the treatment of arterial hypertension Kurt Stoschitzky, MD, FESC Division of Cardiology Department of Internal Medicine Medical University,
Angina Pectoris Dr. Shariq Syed
Angina Pectoris Dr. Syed 1 What is Angina Pectoris (AP)? Commonly known as angina is chest pain often due to ischemia of the heart muscle, Because of obstruction or spasm of the coronary arteries 2 What
Treatment of Essential Hypertension
2016 edition by Mark A. Simmons, PhD Department of Pharmaceutical Sciences School of Pharmacy University of Maryland Eastern Shore Originally developed by Hugh J. Burford, PhD, FCP Department of Pharmacology
Metabolic Consequences of Anti Hypertensives: Is It Clinically Important?
Metabolic Consequences of Anti Hypertensives: Is It Clinically Important?,FACA,FICA,MASH,FVBWG,MISCP CONSULTANT OF CARDIOLOGY DIRECTOR OF PORT-FOUAD HOSPITAL CCU Consideration of antihypertensive agents
QTY LIMIT COPAY (30 DAY/90 DAY) BENIGN PROSTATIC HYPERPLASIA FINASTERIDE $4/$8 $4/$8 $4/$8 $4/$8 $4/$8 $4/$8 $4/$8 $4/$8 $4/$8 $4/$8 $4/$8
2019 LiveWELL Health Plan PREVENTIVE DRUG LIST - GENERIC Names ( Copay) - ALPHABETICAL by DRUG CATEGORY You should always check with your prescriber and/or pharmacist to determine if these alternatives
Medications and your Heart. RBCH Foundation Trust
Medications and your Heart RBCH Foundation Trust Today I will try and cover Confusing cocktail of drugs? What are they for? How do I take them? What if I forget to take them? What are common side effects?
Introducing exciting new Rx benefits 2019
Introducing exciting new x benefits 2019 In 2019, the Middlesex prescription plan is aligning with best-in-class evidence-based practices. Two new tiers will be added that evaluate drugs on the basis of
NOTES: Anemia Medical condition in which the number of red blood cells (the blood count) is reduced.
Advance care planning A process in which you decide what you would like to happen to you, or not happen to you, if you become unable to make decisions about your healthcare treatment or if you are unable
Antihypertensive Drug Procurement Trends from 1995 to 2004: Transition over a Decade. Khalid AJ Al Khaja, PhD*
1 Bahrain Medical Bulletin, Vol. 34, No. 2, June 2012 Antihypertensive Drug Procurement Trends from 1995 to 2004: Transition over a Decade Khalid AJ Al Khaja, PhD* Objective: To evaluate antihypertensive
Pediatric Hypertension. Alisa A. Acosta, MD, MPH Asst. Professor, Renal Section April 5, 2019
Pediatric Hypertension Alisa A. Acosta, MD, MPH Asst. Professor, Renal Section April 5, 2019 Objectives Recognize the importance of accurate blood pressure measurement in pediatric patients Define pediatric
Managing Hypertension in Diabetes Sean Stewart, PharmD, BCPS, BCACP, CLS Internal Medicine Park Nicollet Clinic St Louis Park.
Managing Hypertension in Diabetes 2015 Sean Stewart, PharmD, BCPS, BCACP, CLS Internal Medicine Park Nicollet Clinic St Louis Park Case Scenario Mike M is a 59 year old man with type 2 diabetes managed
State of the art treatment of hypertension: established and new drugs. Prof. M. Burnier Service of Nephrology and Hypertension Lausanne, Switzerland
State of the art treatment of hypertension: established and new drugs Prof. M. Burnier Service of Nephrology and Hypertension Lausanne, Switzerland First line therapies in hypertension ACE inhibitors AT
Intel Connected Care with Providence 2015 Preventive Drug List
Intel Connected Care with Providence 2015 Preventive Drug List Formulary drugs listed below are covered at 100%, not subject to the deductible for the High Deductible Health Plan (HDHP) and Primary Care
Use of Secondary Prevention Drug Therapy in Patients With Acute Coronary Syndrome After Hospital Discharge
RESEARCH Use of Secondary Prevention Drug Therapy in Patients With Acute Coronary Syndrome After Hospital Discharge Helen Y. Lee, PharmD, MBA; Catherine E. Cooke, PharmD, BCPS, PAHM; and Teisha A. Robertson,
Beta blockers in primary hypertension. Dr. Md. Billal Alam Associate Professor of Medicine DMC
Beta blockers in primary hypertension Dr. Md. Billal Alam Associate Professor of Medicine DMC Development of antihypertensive drugs Beta blockers 1958 - The first beta-blocker, dichloroisoproterenol, was
Antihypertensive Drugs. Nafrialdi
Antihypertensive Drugs Nafrialdi 1 Mechanisms of Blood Pressure Regulation Blood Presure Cardiac Output Peripheral Resistance Heart Rate Stroke volume Vascular tone Vessel elasticity Myocardial contractility
Study Exposures, Outcomes:
GSK Medicine: Coreg IR, Coreg CR, and InnoPran Study No.: WWE111944/WEUSRTP3149 Title: A nested case-control study of the association between Coreg IR and Coreg CR and hypersensitivity reactions: anaphylactic
Module 7: Pharmacological Management of Cardiovascular Diseases
Module 7: Pharmacological Management of Cardiovascular Diseases Module Aim This module is an introduction to the pharmacological management of cardiovascular diseases and related risk factors. In this
Cardiovascular drugs
chapter 13 Cardiovascular drugs Cardiovascular drugs act on the heart or blood vessels to control the cardiovascular system. They are used to treat a variety of conditions from hypertension to chronic
Tina Guna Gaja Leban Žiga Sotler. Modul: Na dokazih temelječa medicina 14. skupina Ljubljana,
Tina Guna Gaja Leban Žiga Sotler Modul: Na dokazih temelječa medicina 14. skupina Ljubljana, 26.9.2013 nevropatska bolečina= bolečina, ki je posledica strukturne okvare živčevja ali njegovega motenega
Diabetes and a Healthy Heart. Meeting 6. Welcome! Glucose. Balance Makes a Difference! Medicine Helps with. Glucose. Balance!
6-1 Welcome! Welcome to the lesson! It s good to see you again! Before we visit with Uncle Tommy and Kaipo, let s take a few minutes to review the last five meetings. Glucose Balance Makes a Difference!
1.3.1 Valsartan SPC, Labeling and Package Leaflet SI
1. IME ZDRAVILA Valsacor 80 mg filmsko obložene tablete Valsacor 160 mg filmsko obložene tablete 2. KAKOVOSTNA IN KOLIČINSKA SESTAVA Ena filmsko obložena tableta vsebuje 80 mg ali 160 mg valsartana. Pomožne
New Hypertension Guidelines: How Lower Blood Pressure Targets Affect Medication Safety
New Hypertension Guidelines: How Lower Blood Pressure Targets Affect Medication Safety Diana Isaacs, PharmD, BCPS, BC-ADM, CDE Clinical Pharmacy Specialist Cleveland Clinic Andrew Straw, PharmD, BC-ADM
Antihypertensive drugs SUMMARY Made by: Lama Shatat
Antihypertensive drugs SUMMARY Made by: Lama Shatat Diuretic Thiazide diuretics The loop diuretics Potassium-sparing Diuretics *Hydrochlorothiazide *Chlorthalidone *Furosemide *Torsemide *Bumetanide Aldosterone
Inventory of paediatric therapeutic needs
24 April 2013 EMA/PDCO/246339/2013 Human Medicines Development and Evaluation Cardiovascular therapeutic area Agreed by PDCO August 2012 Adopted by PDCO for release for consultation 15-17 August 2012 Start