Cardiology Vascular Cardiovascular

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1 Cardiology Vascular Cardiovascular

2 Our vision Since its inception, Esaote has been committed to understanding and responding to the most significant diagnostic needs: from the accurate, precise clinical images required by physicians and sonographers to highquality diagnoses necessary to improve quality of life in patients. Today, Esaote is expanding its areas of expertise from diagnosis to prevention and follow-up for all clinical segments and needs. Expert in portable systems High performance Complete range of technologies Wide range of probes Connectivity Portability Two on-board probe connectors Touch screen

3 Esaote provides high-performance Solutions for cardiac care High performance in all modalities A wide range of probes Complete XStrain package (2D and 4D) High performance in b-mode ultrasound solutions and a wide range of cardiovascular technologies. Esaote products include complete solutions for myocardial contractility studies also in portable scanners. All Esaote products deliver high performance in all system sizes. Solutions for vascular care High performance in all modalities A wide range of probes XFlow and HD CFM for hemodynamics evaluation Dedicated advanced tools QIMT - real-time Intima Media Thickness assessment QAS - real-time arterial stiffness assessment A wide range of products Complete set of vascular measurements

4 Innovative clinical solutions that increase Cardiac care Vascular care Clinical needs Assessment of the contractile properties of the heart by Speckle Tracking Echocardiography (STE) to detect the presence of early myocardial disease well before the occurrence of LV global function reduction. Redefine risk stratification, generally performed according to population-based risk factors, on an individual basis to guide the therapy. The success of primary prevention of CVD patients largely depends on early and accurate risk stratification obtained by combining cardiovascular biomarkers with population-based risk scores.. Solution Dedicated complete analysis package 2D & 4D for Strain, Strain Rate, Displacement, Velocity Profile and Torsion. Focus on RF Technologies with high definition and maximum accuracy in Vivo: of 20 micrometers. Advantage Analyze Global Longitudinal STRAIN (GLS) also with mid-range ultrasound and portables, with high resolution. More accurate RF measurements Lower intra-operator variability of RF measurements Ability to estimate central pulse pressure, an important risk factor for CVD.

5 productivity, efficiency and create value Neurosonology Difficult-to-scan patients To add hemodynamic information to the high definition images provided by MRI for suitable use for stroke, ateriovenous malformations, lesions, trauma, etc. The number of difficult-to-scan patients is increasing and is a major challenge in ultrasound. Real-time Fusion Imaging between Ultrasound and one or more second imaging modalities such as MRI and CT. Dedicated filter to increase image quality and single cristal matrix cardiac probe 1-5 MHz. To have visualized on screen in real-time what is usually performed only in the mind of expert neurologists: a full picture of anatomy and hemodynamics of the brain. Improved clinical performance for difficult-to-scan cardiac patients in order to achieve proper diagnostic confidence.

6 Flexibility Wireless ultrasound Easy portability Innovative ready-to-go solutions Comfortable workstations A wide range of accessories Extended export capability to PC (Windows, Mac ) and mobile devices (tablets, smartphones, etc.) Easy networking, both standard and wireless DICOM and IHE compliance MyLab App The new App for visualizing images and videos on mobile devices

7 Solutions for cardiology Probes High performance in standard modalities High performance in 2D and Doppler signal Complete package of CV technologies Strain package with 4D strain technologies Extensive measurement package Measurement configurator LVO Stress echo A wide range of probes TEE probes adult and pediatric Phased array probes adult, pediatrics and neonatal with single crystal technology A large selection of linear transducers from 3 to 22 MHz Left Ventricle Opcification - LVO Strees Echo complete solution IQ Probes - Single Crystal Technology

8 Prevention is the best care The main cultural challenge is to move away from consolidated ORGAN-ORIENTED quantification in favor of a more integrated and comprehensive approach, shifting the perspective from the traditional organ-oriented (heart-based approach) to a new systemic-patient-centered one (heart + nearby vessels such as carotid and coronary artery). CV prevention measures: Myocardial strain IMT + age and sex-specific reference intervals Local carotid stiffness + age and sex-specific reference intervals Local carotid pressure Local femoral stiffness + age and sex-specific reference intervals

9 XStrain 4D XStrain 4D XStrain 2D LV border tracking LV Regional functional parameters Computing Beutel LV surface reconstruction The utilization of LV border tracking obtained with XStrain 2D on standard Apical 4Ch, 2Ch, and Apical LAX views, XStrain 4D delivers a more complete picture of the cardiac mechanics by providing an easy-to-use and intuitive 3D environment in which to evaluate and quantify the several components of the heart s contractile function. XStrain 2D LV Global functional parameters Providing: 1. LV surface rendering and reconstruction 2. Global LV function parameters such as EDV, ESV, SV and EF 3. Regional parameter distributions, including strain, strain rate, myocardial velocity and displacement XStrain 4D Acquisition

10 RF QIMT e RF QAS are technologies used to measure the IMT and stiffness of blood vessel walls. They work with radio frequency signals and provide extremely accurate measurements. Automatic RF-based detection of the Intima and Media Real-time feedback of the quality of measurements Accuracy up to 20 micrometers User interface following the Manheim Consensus Protocol Measurements averaged on six heart beats for improved consistency Quality Intima Media Thickness ( RF QIMT) RF QIMT measure carotid artery s wall thickness. Its combination of ease of use with real-time quality feedback help the operator achieve accurate and reproducible results. To assist physicians in their diagnostic and therapeutic procedures, the measurements (even when taken at different examination times) can be reported on a normalized graph represented by plot indicators. Quality Arterial Stiffness ( RF QAS) RF QAS measures the stiffness of carotid artery walls. Arterial wall stiffness is expressed as the pulse wave velocity obtained from brachial blood pressure and the accurate measurements of diameter and change in diameter. Local blood pressure at the site of the ultrasound measurement is also supplied. Local blood pressure and stiffness are derived from quantification results based on sophisticated clinical studies.

11 The Cardiovascular market requires high performance in standard modalities, extended capabilities and wide range of probes for confidence and reliability in daily clinical practice. Esaote can offer dedicated, cart-based and portable solutions with extended range of technologies, premium performances and a large set of transducers. Key features IQ probes CMM (Compass M-Mode) Pediatrics Probes 2D XStrain 4D XStrain Portable QIMT Stress echo package Shared service QAS LVO TV/TVM MyLabEight MyLabSeven MyLabApha MyLabGamma MyLabOne External External External External External

12 Cardiovascular Windows is a registered trademark of Microsoft Corporation Mac is a registered trademark of Apple Inc Esaote S.p.A. Via di Caciolle, Florence, Italy, Tel , Fax , international.sales@esaote.com Via A. Siffredi, Genoa, Italy, Tel , Fax , info@esaote.com Via E. Melen, Genoa, Italy, Tel , Fax , info@esaote.com Esaote Europe B.V. Philipsweg 1, 6227 AJ Maastricht, The Netherlands FRANCE Esaote Medical SAS ZA du Bel Air 10, rue de Témara, Saint-Germain-en-Laye Tel , Fax info@esaote.fr GERMANY Esaote Biomedica Deutschland GmbH Max-Planck-Straße 27a Köln Tel , Fax info@esaote.de SPAIN Esaote España S.A. C/. Pont Reixat, Sant Just Desvern, Barcelona Tel , Fax info@esaote.es THE NETHERLANDS AND BELGIUM Esaote Benelux B.V. Philipsweg AJ Maastricht Tel , Fax benelux@esaote.nl UK Esaote UK 14, Cambridge Science Park Milton Road, Cambridge, CB4 0FQ Tel , Fax infouk@esaote.com NORTH AMERICA Esaote North America 8000 Castleway Drive, Indianapolis, IN Tel , Fax inquire@esaoteusa.com (MAK Ver.04) BRASIL Esaote Healthcare do Brasil Rua Geraldo Flausino Gomes, 78 CEP: São Paulo - SP Tel Fax comercial@esaote.com.br ARGENTINA Esaote Latinoamérica S.A. San Martín 551, Cuerpo C, Piso 8, (C1004AAK) Buenos Aires Tel , Fax: info@esaote.com.ar INDIA Esaote Asia Pacific Diagnostic Private Limited DLF IT Park, A - 44 & 45, Tower- C, Ground Floor, Sector 62, Noida, Uttar Pradesh, India Pin Code: Tel , Fax info@esaote.in HONG KONG AND FAR EAST Esaote China Ltd 18/F, 135 Bonham Strand Trade Centre, 135 Bonham Strand, Sheung Wan, Hong Kong Tel , Fax esaote@esaotechina.com CHINA Esaote Shenzhen Medical Equipment Room 2608, Tower B Beijing Global Trade Center 36 North Third Ring Road East, Dongcheng District, , Beijing Tel , Fax RUSSIAN FEDERATION AND CIS Esaote S.p.A. 18 Leningradsky prospekt Off. 5 and 6, Moscow Tel , Fax esaotemoscow@yandex.ru Technology and features are system/configuration dependent. Beutel is a trademark of TomTec Imaging Systems GmbH. Specifications subject to change without notice. Information might refer to products or modalities not yet approved in all countries. For further details, please contact your Esaote sales representative. LESS complexity MORE results LESS energy required MORE efficient healthcare

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