Stress testing may be done at a doctor's office or at a hospital. It will usually take between 1 and 3 hours.

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1 STRESS TESTING WHAT IS IT? Stress testing provides your doctor with information about how your heart works during physical stress. Some heart problems are easier to diagnose when your heart is working hard and beating fast. During a stress test, you exercise (walk or run on a treadmill) or are given a medicine to make your heart work harder while heart tests are performed. BASIC FACTS A stress test helps show whether enough blood flows to your heart when it's working hard. Doctors usually use stress testing to help them diagnose coronary artery disease (CAD) or to see how serious this disease is in those who are known to have it. During a stress test, your heart is monitored using images or through dime-sized electrodes attached to your chest, arms, or legs. You may be asked to breathe into a special tube during the test. This will allow your doctor to see how well you're breathing. Standard exercise stress tests use EKGs (electrocardiograms) and breathing and blood pressure monitoring to assess blood flow in the heart. Imaging stress tests, such as those that use echocardiography, or radioactive dyes, show how well blood is flowing in heart muscle. Imaging stress tests tend to be more accurate than standard exercise tests. You may need a stress test if you have CAD symptoms, such as chest pain and shortness of breath. If you've been diagnosed with CAD or recently had a heart attack, you may have stress testing to see whether treatments aimed at improving blood flow in the heart's arteries are needed and likely to help you. Stress testing also is done on people who have signs of an arrhythmia (irregular heartbeat). Stress testing may be done at a doctor's office or at a hospital. It will usually take between 1 and 3 hours. You may have to restrict your diet or not take certain medicines before a stress test. Be sure to wear shoes in which you can exercise comfortably during the stress test. Your health status will always be closely monitored during a stress test, and you will not have to exercise more than you think you can handle. Stress tests are safe and have few side effects. The chance of a stress test causing a heart attack or death is only about 1 in 5,000. You're able to return to all your normal activities after a stress test. If test results are normal, no further testing or treatment is usually needed unless your CAD symptoms persist. If there are abnormal results on your standard exercise stress test, your doctor will probably want you to have an imaging stress test or undergo other testing. But imaging may not be needed if factors other than CAD could explain the abnormal results. Abnormal results on an imaging stress test will require more testing and/or treatment.

2 WHO NEEDS STRESS TESTING? You may need a stress test if you've had chest pains, shortness of breath, or other symptoms of limited blood flow to your heart. Imaging stress tests are particularly helpful in showing whether you have coronary artery disease (CAD) or a problem with one of the valves in your heart. (Heart valves are like doors that let blood flow between the heart's chambers and into the heart's arteries. So, like CAD, faulty heart valves can limit the amount of blood reaching your heart.) If you've been diagnosed with CAD or recently had a heart attack, you may need stress testing to see whether you can tolerate an exercise program. The testing also can show whether treatments designed to improve blood flow in the heart's arteries are necessary and likely to help you. These treatments include angioplasty (with or without stents) and coronary artery bypass grafting. After having one of these treatments, your doctor may want you to have a stress test to see how well the treatment relieves your signs or symptoms of CAD. You also may need a stress test if, during exercise, you feel faint, get a rapid heartbeat or a fluttering feeling in your chest, or have other symptoms of an arrhythmia (an irregular heartbeat). The stress test can detect an arrhythmia and show whether you need medicine or a pacemaker or implantable cardioverter defibrillator (ICD) to correct irregular heartbeats. It also can reveal the effectiveness of such devices. You may need a stress test even if you don't have chest pain when you exercise, but just get short of breath. The test can help show whether a heart problem, rather than a lung problem or being out of shape, is causing your breathing problems. For such testing, you breathe into a special tube so a technician can measure the gases you breathe out. Stress testing isn't routinely done to screen people for CAD. Usually you have to have symptoms of CAD before a doctor will recommend that you have a stress test. But your doctor may want to use a stress test to screen for CAD if you have diabetes, which increases your risk for developing CAD. WHAT TO EXPECT BEFORE STRESS TESTING Standard stress testing can often be done in a doctor's office. Be sure to wear athletic or other shoes in which you can exercise comfortably. You may be asked to wear comfortable clothes in which you can easily exercise, or you may be given a gown to wear during the test. Your doctor may ask you not to eat or drink anything but water for a short time before the test. If you're diabetic, ask your doctor whether you need to adjust your medicines on the day of your test. For some stress tests, you can't drink coffee or other caffeinated drinks for a day before the test. Certain over-the-counter or prescribed medicines also may interfere with some stress tests. Ask your doctor whether you can take all your medicines as usual and whether you need to avoid certain drinks or foods. If you use an inhaler for asthma or other breathing problems, bring it to the test and be sure to let the doctor know that you use it.

3 WHAT TO EXPECT DURING STRESS TESTING During all types of stress testing, a technician will always be with you to closely monitor your health status. Before you start the stress part of a stress test, a technician will put small sticky patches called electrodes on the skin of your chest, arms, and legs. To help an electrode stick to the skin, the technician may have to shave a patch of hair where the electrode will be attached. The electrodes are connected to a machine that records the electrical activity of your heart. This recording, which is called an EKG (electrocardiogram), shows how fast your heart is beating and the heart s rhythm (steady or irregular). The machine also records the strength and timing of electrical signals as they pass through each part of your heart. The technician will put a blood pressure cuff on your arm to monitor your blood pressure during the stress test. (The cuff will feel tight on your arm when it expands every few minutes.) After these preparations, you will exercise on a treadmill or stationary bicycle. During the test, the exercise level will get harder. But you can stop whenever you feel the exercise is too much for you. The illustration shows a patient having a stress test. Electrodes are attached to the patient s chest and connected to an EKG (electrocardiogram) machine. The EKG records the heart s electrical activity. A blood pressure cuff is used to record the patient s blood pressure while he walks on a treadmill. If you can t exercise, a technician will inject a medicine into a vein in your arm or hand. This medicine will increase the flow of blood through the coronary arteries and/or make your heart beat faster, as would exercise. This results in your heart working harder, so the stress test can be performed. The medicine may make you flushed and anxious, but the effects disappear as soon as the test is over. The medicine may also give you a headache.

4 While you re exercising or receiving medicine to make your heart work harder, the technician will ask you frequently how you re feeling. You should tell him or her if you feel chest pain, shortness of breath, or dizzy. The exercise or medicine infusion will continue until you reach a target heart rate, or until you: Feel moderate to severe chest pain Get too out of breath to continue Develop abnormally high or low blood pressure or an arrhythmia (an abnormal heartbeat) Become dizzy The technician will continue to monitor your heart functions and blood pressure for a short time after you stop exercising or stop receiving the stress-creating medicine. The stress part of a stress test (when you re exercising or given a medicine that makes your heart work hard) usually lasts only about 15 minutes or less. But there is preparation time before the test and monitoring time afterward. Both extend the total test time to about an hour for a standard stress test, and up to 3 hours or more for some imaging stress tests. EXERCISE STRESS ECHOCARDIOGRAM TEST For an exercise stress echocardiogram test, the technician will take pictures of your heart using echocardiography before you exercise and after you finish. A sonographer (a person who specializes in using ultrasound techniques) will apply a gel to your chest and then will briefly put a wand-like device (called a transducer) against your chest and move it around. The transducer sends and receives high-pitched sounds that you usually can t hear. The echoes from the sound waves are converted into moving pictures of your heart on a screen. You may be asked to lie on your side on an examining table for this test SESTAMIBI STRESS TEST OR OTHER IMAGING STRESS TEST INVOLVING RADIOACTIVE DYE For a sestamibi or other imaging stress test that uses a radioactive dye, the technician will inject a small amount of the dye (such as sestamibi) into your bloodstream via a needle placed in a vein of your arm or hand. You re usually given the dye about a half-hour before you start exercising or are given a medicine that makes your heart work hard. The amount of radiation in the dye is safe and not a danger to you or those around you. However, if you re pregnant, you shouldn t have this test because of risks it might pose to your unborn child. Pictures will be taken of your heart at least two times when it s at rest and when it s working its hardest. For such imaging, you will lie down on a table and a special camera or scanner that can see the dye in your bloodstream will take pictures of your heart. Some pictures may not be taken until you lie quietly for a few hours after exercising or receiving the stress-creating medicine. Some patients may even be asked to return in a day or so for more pictures to be taken.

5 WHAT TO EXPECT AFTER STRESS TESTING After stress testing, you're able to return to normal activities. If you had a test that involved radioactive dye, your doctor may ask you to drink plenty of fluids to flush it out of your body. You also shouldn't have certain other imaging tests until the dye is no longer in your body. Your doctor can advise you about this. WHAT DOES STRESS TESTING SHOW? Stress testing provides your doctor with information about how your heart works during physical stress (exercise) and how healthy your heart is. Standard exercise stress testing uses an EKG (electrocardiogram) to monitor changes in the electrical activity of your heart. Imaging stress tests take pictures of the blood flow to different parts of your heart. Both types of stress testing are used to look for signs that your heart isn't getting enough blood flow during exercise. Abnormal results on stress testing may be due to coronary artery disease (CAD), but also can be due to other factors such as a lack of physical fitness. If you have a standard exercise stress test and the results are normal, no further testing or treatment may be needed. But if your standard exercise stress test results are abnormal, or if you're physically unable to exercise, your doctor may want you to have an imaging stress test or undergo other testing. Even if your standard exercise stress test results are normal, your doctor may want you to have an imaging stress test if you continue having symptoms (such as shortness of breath or chest pain). Standard exercise stress testing isn't equally accurate in men and women. Normal results from a standard exercise stress test usually accurately rule out CAD in both men and women. But a standard exercise stress test can show abnormal results even when the patient doesn't have CAD (these results are called false positives). False positive exercise stress tests happen more often in women than in men. Imaging stress tests are more accurate than standard exercise stress tests (in men and women) because they directly show how well blood is flowing in heart muscle and reveal parts of the heart that aren't contracting strongly. But imaging stress tests are much more expensive than standard exercise stress tests. Imaging stress tests can show the parts of the heart not getting enough blood, as well as dead tissue in the heart, where no blood flows. (A heart attack can cause some tissue in the heart to die.) If your imaging stress test suggests significant CAD, your doctor may want you to have more testing and/or treatment. WHAT ARE THE RISKS OF STRESS TESTING? There's little risk of being seriously harmed from any type of stress testing. The chance of these tests causing a heart attack or death is about 1 in 5,000. More common but less serious side effects linked to stress testing include:

6 Arrhythmia (an irregular heartbeat). This often will go away quickly once you're at rest. But if it persists, you may need to go to the hospital and be monitored or get treatment. Low blood pressure, which can cause you to feel dizzy or faint. This will go away once your heart stops working hard; it doesn't usually require treatment. Jitteriness or discomfort while getting medicine to make your heart work harder (you will be given medicine if you can't exercise). These side effects usually disappear shortly after you stop getting the medicine, but in some cases may last a few hours. SOURCE National Institutes of Health (U.S. Department of Health and Human Services)

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