Routine low-radiation-dose coronary computed tomography angiography
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1 European Heart Journal Supplements (2014) 16 (Supplement B), B12 B16 The Heart of the Matter doi: /eurheartj/suu024 Routine low-radiation-dose coronary computed tomography angiography Mouaz H. Al-Mallah 1,2 *, Ahmed Aljizeeri 1, Mohsen Alharthi 1,2, and Ahmed Alsaileek 1,2 1 Division of Advanced Cardiac Imaging, King Abdulaziz Cardiac Center, King Abdulaziz Medical City, Ministry of National Guard - Health Affairs, PO BOX 22490, Riyadh 11426, Kingdom of Saudi Arabia 2 King Saud bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia KEYWORDS Radiation dose; Coronary computed tomography angiography Introduction In recent years, coronary computed tomography angiography (CCTA) has emerged as a novel tool for the noninvasive detection of coronary artery disease (CAD). 1,2 Multiple studies have demonstrated its high sensitivity and a negative predictive value for the detection and exclusion of CAD. 3,4 However, CCTA was limited by the use of high-radiation doses, which may lead to downstream malignancies in the future. 5,6 In addition, a multicenter study demonstrated significant variability in the radiation * Corresponding author. Tel: , Ext , Fax: , Ext , mouaz74@gmail.com Recent advances in coronary computed tomography angiography (CCTA) increased its utilization as a tool for non-invasive detection of coronary artery disease (CAD). The aim of this analysis is to determine the impact of adopting new radiation dose-reducing techniques on the radiation exposure in consecutive patients undergoing CCTA. We included 1341 consecutive patients who underwent CCTA to rule out CAD between January 2007 and December New dose-reducing techniques were adopted in July 2010 in 1034 patients. These included high pitch scanning, 100 KVP (Kilovoltage Peak) imaging, and iterative reconstruction. The total radiation dose was calculated for each scan from the dose length product multiplied by conversion factor (0.014). The annual median radiation doses were compared over the study period. After the adoption of the new scanning techniques (n ¼ 578), 53% of the scans were done with high pitch scanning, 46% with prospective gating, and 1% with retrospective gating. This was associated with.90% reduction in the radiation doses with a median radiation dose of 2.7, 1.5, 1.7, and 1.5 msv (Millisievert) in 2010, 2011, 2012, and 2013, respectively. A total of 15 and 66% of the CCTA scans had a radiation dose of,1 and 2 msv, respectively. There was no difference in the frequency of non-diagnostic studies or imaging quality before and after July Our analysis demonstrates that, in the current era, low-radiation CCTA can be routinely done in clinical practice. exposure associated with CCTA, even among users of the same scanners. 6 In the past few years, all vendors developed new tools that allow to minimize the radiation exposure associated with CCTA, like prospective gating, 100 KVP (Kilovoltage Peak) imaging, iterative reconstruction, high pitch scanning and volumetric imaging. 7,8 Two single-center studies suggested that the utilization of these tools would result in a significant reduction in the associated radiation dose in a highly selected subgroup of patients. 9,10 However, there are limited data on whether these tools can be utilized in all consecutive patients undergoing CCTA. Thus, the aim of this analysis is to determine whether lowradiation doses can be routinely achieved in all consecutive patients referred for CCTA. Published on behalf of the European Society of Cardiology. All rights reserved. & The Author For permissions please journals.permissions@oup.com
2 Routine low-radiation-dose coronary computed tomography angiography B13 Methods We included consecutive patients who underwent coronary CT angiography for the exclusion of CAD between September 2006 and December Patients younger than 18 years old were excluded from this analysis. In addition, patients with known CAD (prior myocardial infarction, prior angioplasty, and coronary artery bypass grafting), atrial fibrillation, and patients undergoing non-coronary cardiac CTwere excluded from this analysis. Coronary computed tomography angiography image acquisition All CCTA scans were performed on either a 64-multidetector row scanner (High Definition Scanner, General Electric, Milwaukee, WI, USA) or a dual source cardiac CTsystem with high pitch scanning capability (Siemens Healthcare, Erlangen, Germany). Patients were in normal sinus rhythm and were capable of the breath-hold needed for CCTA. For patients presenting with baseline heart rates.65 b.p.m., beta-blockers were administered to slow the heart rate. Following a scout radiograph, contrast timing was determined using a test bolus (15 ml contrast) to detect optimal time for peak contrast opacification in the ascending aorta. Nitroglycerine sublingually was administered immediately before contrastinjection. During CCTA acquisition, ml of iodinated contrast was injected followed by a ml saline flush. All CCTA scans were attended and sometimes performed by a consultant cardiologist with special training in CCTA. Radiation dose reduction program In July 2010, the new radiation reduction tools became available in our center and were strictly utilized for every CCTA. A radiation reduction protocol was developed and included minimizing longitudinal scan range; use of sufficient beta-blockers to control heart rate and heart rate variability; using 100 KVP for patients with body mass index,30 kg/m 2 ; use of high pitch scanning when possible; and minimizing the milliamperage used and applying iterative reconstruction in all cases in addition to direct supervision of the CCTA by a consultant physician. 5 Estimation of radiation dose Radiation doses were estimated from the scanner provided protocol summary that contain the dose length product for each image series, which integrated estimated absorbedradiation in the x-, y-, and z-directions based on the CT dose index volume. The effective radiation dose was derived from the summed dose length product Table 1 Baseline characteristics of the study population multiplied by the European Working Group for Guidelines on Quality Criteria in Computed Tomography conversion coefficient (k ¼ msv (Millisievert)/mGy cm). 6 Image quality assessment Physicians rated the quality of each image on a per-patient basis at the time of scan interpretation. This is adopted from the prior published criteria. 5 Excellent (score ¼ 1) was defined as the complete absence of motion artefacts, excellent signal-to-noise ratio, and clear delineation of vessel walls, with the ability to assess luminal stenosis as well as plaque characteristics. Good (score ¼ 2) was defined as non-limiting motion artefacts, reduced signal-to-noise ratio, and/or calcifications are present, with preserved ability to assess luminal stenosis as well as plaque characteristics. Fair (score ¼ 3) was defined as reduced image quality due to any combination of noise, motion, poor contrast enhancement, or calcium that significantly impairs ease of interpretation, but image quality is sufficient to rule out significant stenosis. Non-diagnostic (score ¼ 4) was defined as reduced image quality that precludes adequate assessment of stenosis in the majority of vessels. Statistical analysis Patients were grouped into two groups, before and after July Group comparisons were conducted between the two groups using x 2 testing or Students t-testing when appropriate. Results A total of 1341 patients underwent CCTA in the study period with 307 patients (23%) before July The baseline characteristics of the included patients are summarized in Table 1. After July 2010, patients undergoing CCTA had a lower risk profile with less frequent hypertension, diabetes, and dyslipidaemia. However, there was no difference in the body mass index of the patients before or after the implementation of the low-radiation CCTA program (Table 1). In accordance to the low-radiation protocol, the higher radiation retrospective gating protocol was rarely used after July 2010 as presented in Table 2 (,1%). Most patients were scanned using the lower radiation protocols (prospective gating 46% and high pitch scanning 52%) and more often with 100 KVP imaging (Figure 1) Before July 2010 After July 2010 P-value Mean age (years) Male gender 69% 58%, Hypertension 66% 52%, Diabetes 44% 36% Dyslipidaemia 70% 56%, Smoking 28% 18% Mean body mass index (kg/m 2 ) Group comparisons are made before and after the implementation of the low-radiation imaging protocols.
3 B14 M.H. Al-Mallah et al. Table 2 Scanning parameters before and after the implementation of the low-radiation imaging protocols Before July 2010 After July 2010 P-value Mean heart rate (b.p.m.) Mode of image acquisition Prospective gating 10% 46%, Retrospective gating 90% 1% High pitch scanning 0% 53% Figure 1 Utilization of the low tube voltage before and after the implementation of a low-radiation-dose imaging protocol. As per the protocol, more patients are imaged with the lower voltage despite no change in the body mass index of the patients before and after July Figure 2 Median annual radiation dose. There was.90% drop in the radiation dose after the implementation of low-radiation-dose imaging protocol (P, ). It was also sustained for 4 years. Adherence to the low-radiation protocol resulted in a significant drop in the radiation dose from a median of msv after July 2010 (Figure 2). Most patients after July 2010 had a radiation dose of,2 msv as shown in Figure 3. Only 6.2% of the study population had a radiation dose of.5 msv after July 2010, compared with 91% prior to July 2010 (P, ). Most importantly, there were no differences in the image quality before or after the implementation of the low-radiation protocol or in the rate of poor quality scans (Figure 4).
4 Routine low-radiation-dose coronary computed tomography angiography B15 Figure 3 Percentage of patients according to the radiation dose (P, ). Coronary computed tomography angiography with a radiation dose of,5 msv was rarely possible before July Figure 4 Image quality before and after the implementation of low-radiation-dose imaging protocol. There were no differences in the image quality before or after the implementation of the low-radiation protocol or in the rate of poor quality scans. Discussion Our analysis shows that, in the current era, low-radiation CCTA can be routinely used in consecutive patients without prior CAD. This is possible with the utilization of the new imaging radiation lowering techniques and tools that allow the minimization of radiation exposure without impacting the image quality or the diagnostic accuracy of the study. Our analysis is in agreement with prior analysis from the advanced consortium of cardiovascular imaging analysis from the state of Michigan, which showed that utilizing radiation exposure lowering measures would allow for routine low-dose CCTA. The median radiation dose in the consortium was 4.8 msv at the end of the study. 11 In our analysis, we took this further and showed that the radiation dose can be lowered further to,2 msv. This is achieved primarily by applying iterative reconstruction in every patient and selecting the imaging protocol that is associated with the least radiation exposure according to the patient s clinical status. In addition, the presence of the physician by the scanner console in every case allowed for adjusting the scanning parameters and achieving this result. In conclusion, we have shown that in the current CCTA can be and should be routinely done in consecutive patients with low-radiation doses. Conflict of interest: none declared. References 1. Achenbach S, Friedrich MG, Nagel E, Kramer CM, Kaufmann PA, Farkhooy A, Dilsizian V, Flachskampf FA. CV imaging: what was new in 2012? JACC Cardiovasc Imaging 2013;6:
5 B16 M.H. Al-Mallah et al. 2. Perrone-Filardi P, Achenbach S, Mohlenkamp S, Reiner Z, Sambuceti G, Schuijf JD, Van der Wall E, Kaufmann PA, Knuuti J, Schroeder S, Zellweger MJ. Cardiac computed tomography and myocardial perfusion scintigraphy for risk stratification in asymptomatic individuals without known cardiovascular disease: a position statement of the working group on nuclear cardiology and cardiac CTof the European Society of Cardiology. Eur Heart J 2011;32: a, b. 3. Budoff MJ, Dowe D, Jollis JG, Gitter M, Sutherland J, Halamert E, Scherer M, Bellinger R, Martin A, Benton R, Delago A, Min JK. Diagnostic performance of 64-multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis in individuals without known coronary artery disease: results from the prospective multicenter accuracy (assessment by coronary computed tomographic angiography of individuals undergoing invasive coronary angiography) trial. J Am Coll Cardiol 2008;52: Raff GL, Gallagher MJ, O Neill WW, Goldstein JA. Diagnostic accuracy of noninvasive coronary angiography using 64-slice spiral computed tomography. J Am Coll Cardiol 2005;46: RaffGL, ChinnaiyanKM, ShareDA, Goraya TY, KazerooniEA, MoscucciM, Gentry RE, Abidov A. Radiation dose from cardiac computed tomography before and after implementation of radiation dose-reduction techniques. JAMA 2009;301: Hausleiter J, Meyer T, Hermann F, Hadamitzky M, Krebs M, Gerber TC, McCollough C, Martinoff S, Kastrati A, Schomig A, Achenbach S. Estimated radiation dose associated with cardiac CT angiography. JAMA 2009;301: Leipsic J, Labounty TM, Heilbron B, Min JK, Mancini GB, Lin FY, Taylor C, Dunning A, Earls JP. Estimated radiation dose reduction using adaptive statistical iterative reconstruction in coronary CT angiography: The ERASIR study. AJR Am J Roentgenol 2010;195: Leipsic J, Labounty TM, Heilbron B, Min JK, Mancini GB, Lin FY, Taylor C, Dunning A, Earls JP. Adaptive statistical iterative reconstruction: assessment of image noise and image quality in coronary CTangiography. AJR Am J Roentgenol 2010;195: Fuchs TA, Stehli J, Bull S, Dougoud S, Clerc OF, Herzog BA, Buechel RR, Gaemperli O, Kaufmann PA. Coronary computed tomography angiography with model-based iterative reconstruction using a radiation exposure similar to chest X-ray examination. Eur Heart J 2014;35: Achenbach S, Marwan M, Ropers D, Schepis T, Pflederer T, Anders K, Kuettner A, Daniel WG, Uder M, Lell MM. Coronary computed tomography angiography with a consistent dose below 1 msv using prospectively electrocardiogram-triggered high-pitch spiral acquisition. Eur Heart J 2010;31: Chinnaiyan KM, Boura JA, DePetris A, Gentry R, Abidov A, Share DA, Raff GL. Progressive radiation dose reduction from coronary computed tomography angiography in a statewide collaborative quality improvement program: results from the advanced cardiovascular imaging consortium. Circ Cardiovasc Imaging 2013;6:
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