The Author(s) This article is published with open access by ASEAN Federation of Cardiology

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1 DOI /s ASEAN Heart Journal Vol. 22, no. 1, (2014) ISSN: Erratum Erratum to: Impact Of Sex On Clinical Characteristics And In-Hospital Outcomes In A Multi-Ethnic Southeast Asian Population Of Patients Hospitalized For Acute Heart Failure Peter Chang 1, Shaw Yang Chia 2, Ling Ling Sim 2, Fei Gao 2, Fong Ling Lee 3, Ping Chai 1, Raymond Ching-Chiew Wong 1, Swee Chong Seow 1, Gerard Kui Toh Leong 4, Poh Shuan Daniel Yeo 5,6, David Sim 2, Terrance Chua 2, Bernard W.K. Kwok 2, Carolyn S.P. Lam 1 1 Cardiac Department, National University Health System, Singapore 2 Department of Cardiology, National Heart Centre Singapore 3 Department of Cardiology, Khoo Teck Puat Hospital, Singapore 4 Department of Cardiology, Changi General Hospital, Singapore 5 Department of Cardiology, Tan Tock Seng Hospital, Singapore 6 Apex Heart Clinic, Gleneagles Hospital, Singapore, Singapore Cardiac Data Bank The Author(s) This article is published with open access by ASEAN Federation of Cardiology The original version of the article was published in ASEAN Heart Journal, Vol. 22, Issue 1, (2014), DOI /s y. Unfortunately, some tables and figures were missing in the original version. The missing tables and figures are presented below. Table 1: Baseline study population characteristics Figure 1: Differences in Baseline Characteristics Table 2: Discharge medications Table 3: Outcome Table 4: Univaraible predictors of mortality or rehospitalization Table 5: Multivariable predictors of mortality or rehospitalization by gender Table 6: Multivariate predictors of mortality or rehospitalization by LVEF Correspondence to Carolyn S.P. Lam, National University Health System 1E Kent Ridge Road, Singapore Tel: ; Fax: carolyn_lam@nuhs.edu.sg 60

2 Table 1: Baseline study population characteristics Women (n=2635) Men (n=3068) P-value Mean age, year < Hypertension, % < Diabetes, % < CAD, % < Prior MI, % < PVD, % Current smoker, % < Fatigue, % Rales, % Peripheral edema, % Mean SBP, mmhg 147± ± 39 < Mean HR, bpm 89 ± ± % A-fib/flutter < Mean Na, mmol/l 137±6 137± Median scr, umol/l 99 (74, 144) 117 (94, 159) < Median BUN, mmol/l 6.8 (5, 10) 7.0 (5, 10) Median Hb, g/dl 11.5 (10, 13) 12.9 (11, 45) < Anemia, % < LVEF 50% < Initial ED care, % General ward care, % Mechanical ventilation, % Dialysis, % Coronary angiography, % <0.001 CPR, % CAD, coronary artery disease; LVEF, left ventricular ejection fraction; PVD, peripheral disease; SBP, systolic blood pressure; ED, emergency departmentvascular, CPR, cardiopulmonary resuscitation. Data are mean ± SD or median (25 th, 75 th percentile). 61

3 Figure 1. Differences in Baseline Characteristics Afib, atrial fibrillation; LVEF, left ventricular ejection fraction; CAD, coronary artery disease; MI, myocardial infarction. Table 2. Discharge medications Women Men P-value Women Men P-value Women Men P-value (n=2635) (n=3068) (n=1119) (n=638) (n=1516) (n=2430) ACEI, % < < <0.001 ARB, % < <0.001 ACEI or ARB, % < <0.001 Aldosterone < <0.001 antagonist, % Loop diuretics, % < Nitrates, % < Digoxin, % < Beta-blocker, % < ACEI, angiotensin converting enzyme inhibitor; ARB, angiotensin receptor. blocker. Table 3. Outcome Women Men P-value Women Men P-value Women Men P-value (n=2635) (n=3068) (n=1119) (n=638) (n=1516) (n=2430) Mean Length of stay, d < In-hospital Mortality, % Rehospitalization, %

4 Table 4: Univaraible predictors of mortality or rehospitalization Women (n=2635) Men (n=3068) Risk Factors HR (95% CI) P-value HR (95% CI) P-value Log Age 4.41 ( ) < ( ) <.001 LVEF <50% 0.79 ( ) < ( ) <.001 Renal Disorder 1.55 ( ) < ( ) <0.001 HTN 0.96 ( ) ( ) CAD 1.25 ( ) < ( ) Prior MI 1.49 ( ) < ( ) <.001 Diabetes 1.25 ( ) < ( ) PVD 1.47 ( ) ( ) <.001 Prior CVA/TIA 1.31( ) ( ) Current smoker 0.75 ( ) ( ) COPD 1.07 ( ) ( ) Hyperlipidemia 1.10 ( ) ( ) Atrial Fibrillation 1.20 ( ) ( ) Peripheral edema 1.09 ( ) ( ) Anemia 1.36 ( ) < ( ) <.001 Discharge ACEI or ARB 0.71 ( ) < ( ) <.001 Discharge beta-blocker 0.84 ( ) ( ) <.001 Discharge Aspirin 0.78 ( ) < ( ) Discharge lipid-lowering 0.82 ( ) ( ) <.001 Discharge loop diuretics 0.91 ( ) ( ) <.001 CAD, coronary artery disease; LVEF, left ventricular ejection fraction; HTN, hypertension; MI, myocardial infarction; PVD, peripheral disease; CVA, cerebralvascular accident; TIA, transient ischemic attack; ACEI, angiotensin converting enzyme inhibitor; ARB, angiotensin receptor blocker. 63

5 Table 5: Multivariable predictors of mortality or rehospitalization by gender Women (n=2,635) Men (n=3,068) HR (95% CI) P-value HR (95% CI) P-value Age 1.01 ( ) ( ) 0.01 Renal Disorder 1.42 ( ) ( ) 0.37 Prior MI 1.69 ( ) < ( ) <0.001 Afib 1.28 ( ) ( ) 0.10 Diabetes 1.27 ( ) ( ) 0.38 PVD 1.01 ( ) ( ) 0.12 LVEF < ( ) ( ) <0.001 Hypertension 0.83 ( ) ( ) 0.47 Anemia 1.12 ( ) ( ) <0.001 Discharge Beta Blocker 0.79 ( ) ( ) <0.001 Discharge ACE/ARB 0.78 ( ) ( ) LVEF, left ventricular ejection fraction; Afib, atrial fibrillation; ACEI, angiotensin converting enzyme inhibitor; ARB, angiotensin receptor blocker. 64

6 Table 6. Multivariate predictors of mortality or rehospitalization by LVEF Normal EF Abnormal EF HR (95% CI) P-value HR (95% CI) P-value Age 1.01 ( ) ( ) <0.001 Sex 1.22 ( ) ( ) Renal Disorder 1.42 ( ) ( ) Prior MI 1.95 ( ) < ( ) <0.001 Prior CVA 1.07 ( ) ( ) Afib 1.30 ( ) ( ) Diabetes 1.04 ( ) ( ) Hypertension 0.70 ( ) ( ) Admission BUN 1.06 ( ) < ( ) <0.001 Anemia 1.19 ( ) ( ) <0.001 Discharge Beta Blocker 0.80 ( ) ( ) <0.001 Discharge ACEI or ARB 0.76 ( ) ( ) MI, myocardial infarction; CVA, cerebralvascular accident; CVA, cerebralvascular accident; ACEI, angiotensin converting enzyme inhibitor; ARB, angiotensin receptor blocker. 65

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