M. Pharm. (Pharmacology) TERMINOLOGY:- S MEANS SEMESTER. MPL MEANS MASTER OF PHARMACOLOGY. L MEANS LECTURE. T MEANS TUTORIAL. P MEANS PRACTICAL.

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1 M Pharm (Pharmacology) TERMINOLOGY:- S MEANS SEMESTER MPL MEANS MASTER OF PHARMACOLOGY L MEANS LECTURE T MEANS TUTORIAL P MEANS PRACTICAL Semeste r Third Subject code Subject Hours/week Marks L T P Mid Sem Exam Assign / Quiz T A End Sem Exam S3-MPL-1P Research Project (P) S3-MPL-2P Research Work Seminar (P) S3-MPL-3 Methods in Pharmacology Total S3-MPL-3P Methods in Pharmacology (P) S3-MPL-4 Elective Total

2 Name of the Course : Research Project (P) Course code: S3-MPL-1P Duration : 240 Hrs Maximum Marks : 150 Practical : 12 Hrs/week Mid Semester Exam: 40 Marks Assignment & Quiz: 00 Marks T A: 10 Marks End Semester Exam:100 Marks Name of the Course : Research work Seminar (P) Course code: S3-MPL-2P Duration : 120 Hrs Maximum Marks : 150 Practical : 08 Hrs/week Mid Semester Exam: 40 Marks Assignment & Quiz: 00 Marks T A : 10 Marks

3 Name of the Course : Methods in Pharmacology Course code: S3-MPL- 3 Duration : 40 Hrs Maximum Marks : 150 Theory : 03 Hrs/week Mid Semester Exam:30 Marks Tutorial: 01 Hrs/week Assignment & Quiz: 10 Marks T A: 10 Marks Unit -1 Content Regulations for Laboratory animal use and care Limitations and alternatives to animal use Principles involved inpreclinical evaluation of new drugs Blind screening programme, Preclinical Safety Assessment tests including carcinogenicity and reproductive studies Hrs Unit -2 Critical assessment, limitations, and validation criteria of animal models, employed to evaluate the drugs belonging to following categories: Hypertension Angina, Arrhythmia, Cardiac failure, Atherosclerosis Epilepsy, Parkinsonism, Anxiety, Depression, Psychosis 09 Unit -3 Stress Cognitive disorders and Alzheimer s disease 04 Unit -4 CNS stimulants and Depressants, Analgesics and drugs used in Neuropathic pain, Inflammation and Arthritis Unit -5 Antihistaminics, Antidiabetics, Antifertility, Hepatoprotective and Antiobesity and Anticancer drugs Unit -6 Bioassay of drugs 09 Total 40 Text Books: It is strongly recommended that some standard book/s be used for practicals The choice of book/s is left to the concerned teachers Reference books : 1 HG Vogel, 2002 Drug Discovery and Evaluation-Pharmacological Assays, 2 nd Ed Springer Verlag, Berlin, Germany 2 DR Laurence and AL Bacharach, 1964 Evaluation of Drug Activities: Pharmacometerics Vol 1 and 2, Academic Press, London, UK 3 RA Turner, 1965 Screening methods in pharmacology, Academic press, New York 4 A Schwartz, Methods in Pharmacology Plenum Publishing Corporation 5 HHSiddiqui, 2009, Bioassay of drugs, Globalmedic, New Delhi

4 Name of the Course : Methods in Pharmacology (P) Course code: S3-MPL- 3P Duration : 60 Hrs Maximum Marks : 150 Practical : 08 Hrs/week Mid Semester Exam:30 Marks Assignment & Quiz: 10 Marks T A: 10 Marks List of Laboratory Experiments : 1 Problem solving exercises on acute toxicity tests to find out LD50 of a drug 2 Experiments to study anti-inflammatory, analgesic, antipyretic and anticonvulsant activity of a Drug 3 Experiments to study anti anxiety effect of diazepam in mice 4 Experiments to study antidiabetic activity of a drug

5 Name of the Course : Elective 2 Course code: S3-MPL-4 Duration : 40 Hrs Maximum Marks : 150 Theory : 03 Hrs/week Mid Semester Exam:30 Marks Tutorial: 01 Hrs/week 1 Safety pharmacology 2 Concept of Essential drugs 3 Pharmacoeconomics 4 Drug therapy in Geriatrics Content Assignment & Quiz:10 Marks T A: 10 Marks Hrs 5 Drug therapy in pregnancy and Pediatrics 6 Drug Interactions Total 40 Text Books: N A Reference books : 1 SC Gad, 2000 Safety assessment for pharmaceuticals, John Wiley & Sons, New York 2 JR Turner, 2007 New drug development: design, methodology, and analysis, Wiley- Interscience 3 A Dmitrienko, C Chuang-Stein, and R D'Agostino, 2007 Pharmaceutical statistics using SAS: a practical guide, SAS Institute 4 CG Smith, and J O'Donnell, 20 The process of new drug discovery and development, 2 nd ed, Informa Healthcare, New York 5 RD Mann, and EB Andrews, 2007 Pharmacovigilance 2 nd ed, John Wiley & Sons Chichester, England 6 World Health Organization, 2004 WHO guidelines on safety monitoring of herbal medicines in pharmacovigilance systems, World Health Organization 7 BL Cobert, 2007 Manual of drug safety and pharmacovigilance, Jones and Bartlett Publishers 8 SC Gad, 2009 Drug safety evaluation, Wiley Interscience, New York 9 Relevant OECD guidelines (Internet resources)

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