Drugs That Require Step Therapy (ST) Step Therapy Medications

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1 Drugs That Require Step Therapy (ST) In some cases, BlueShield of Northeastern New York requires you to first try certain drugs to treat your medical condition before we will cover another drug for that condition. For example, if Step-1 and Step-2 drugs both treat your medical condition, we may not cover the Step-2 drug unless you try the Step-1 drug first. If the Step-1 drug does not work for you, we will then cover the Step-2 drug. You will need authorization from BlueShield of Northeastern New York before filling prescriptions for the Step-2 drugs shown in the chart below. BlueShield of Northeastern New York will only provide coverage after it determines that the drug is being prescribed according to the criteria specified in the chart. You, your appointed representative, or your prescriber can request a review by calling Member Services at (TTY only, call 711). We are open October 1 - February 14 8 a.m. to 8 p.m., 7 days a week and February 15 -September 30 8 a.m. to 8 p.m., Monday - Friday. Calls to these numbers are free. You can also visit our website, Step Therapy Medications Step Therapy alpha blockers Step-1: ALFUZOSIN ER 10 MG TABLET,EXTENDED RELEASE 24 HR or DOXAZOSIN 1 MG TABLET or DOXAZOSIN 2 MG TABLET or DOXAZOSIN 4 MG TABLET or DOXAZOSIN 8 MG TABLET or TAMSULOSIN 0.4 MG CAPSULE or TERAZOSIN 1 MG CAPSULE or TERAZOSIN 10 MG CAPSULE or TERAZOSIN 2 MG CAPSULE or TERAZOSIN 5 MG CAPSULE Step-2: RAPAFLO 4 MG CAPSULE or RAPAFLO 8 MG CAPSULE Page 1

2 dpp-4 inhibitorspst Step-1: JANUMET 50 MG-1,000 MG TABLET or JANUMET 50 MG-500 MG TABLET or JANUMET XR 100 MG-1,000 MG TABLET,EXTENDED RELEASE or JANUMET XR 50 MG-1,000 MG TABLET,EXTENDED RELEASE or JANUMET XR 50 MG-500 MG TABLET,EXTENDED RELEASE or JANUVIA 100 MG TABLET or JANUVIA 25 MG TABLET or JANUVIA 50 MG TABLET or KOMBIGLYZE XR 2.5 MG-1,000 MG TABLET,EXTENDED RELEASE or KOMBIGLYZE XR 5 MG-1,000 MG TABLET,EXTENDED RELEASE or KOMBIGLYZE XR 5 MG-500 MG TABLET,EXTENDED RELEASE or ONGLYZA 2.5 MG TABLET or ONGLYZA 5 MG TABLET Step-2: JENTADUETO 2.5 MG-1,000 MG TABLET or JENTADUETO 2.5 MG-500 MG TABLET or JENTADUETO 2.5 MG-850 MG TABLET or KAZANO 12.5 MG- 1,000 MG TABLET or KAZANO 12.5 MG-500 MG TABLET or NESINA 12.5 MG TABLET or NESINA 25 MG TABLET or NESINA 6.25 MG TABLET or TRADJENTA 5 MG TABLET Page 2

3 enhanced arb Step-1: AMLODIPINE 10 MG-VALSARTAN 160 MG TABLET or AMLODIPINE 10 MG-VALSARTAN 160 MG-HYDROCHLOROTHIAZIDE 12.5 MG TABLET or AMLODIPINE 10 MG-VALSARTAN 160 MG-HYDROCHLOROTHIAZIDE 25 MG TABLET or AMLODIPINE 10 MG-VALSARTAN 320 MG TABLET or AMLODIPINE 10 MG-VALSARTAN 320 MG-HYDROCHLOROTHIAZIDE 25 MG TABLET or AMLODIPINE 5 MG-VALSARTAN 160 MG TABLET or AMLODIPINE 5 MG-VALSARTAN 160 MG-HYDROCHLOROTHIAZIDE 12.5 MG TABLET or AMLODIPINE 5 MG-VALSARTAN 160 MG-HYDROCHLOROTHIAZIDE 25 MG TABLET or AMLODIPINE 5 MG-VALSARTAN 320 MG TABLET or CANDESARTAN 16 MG TABLET or CANDESARTAN 16 MG- HYDROCHLOROTHIAZIDE 12.5 MG TABLET or CANDESARTAN 32 MG TABLET or CANDESARTAN 32 MG-HYDROCHLOROTHIAZIDE 12.5 MG TABLET or CANDESARTAN 32 MG-HYDROCHLOROTHIAZIDE 25 MG TABLET or CANDESARTAN 4 MG TABLET or CANDESARTAN 8 MG TABLET or EPROSARTAN 600 MG TABLET or IRBESARTAN 150 MG TABLET or IRBESARTAN 150 MG-HYDROCHLOROTHIAZIDE 12.5 MG TABLET or IRBESARTAN 300 MG TABLET or IRBESARTAN 300 MG- HYDROCHLOROTHIAZIDE 12.5 MG TABLET or IRBESARTAN 75 MG TABLET or LOSARTAN 100 MG TABLET or LOSARTAN 100 MG- HYDROCHLOROTHIAZIDE 12.5 MG TABLET or LOSARTAN 100 MG- HYDROCHLOROTHIAZIDE 25 MG TABLET or LOSARTAN 25 MG TABLET or LOSARTAN 50 MG TABLET or LOSARTAN 50 MG-HYDROCHLOROTHIAZIDE 12.5 MG TABLET or TELMISARTAN 20 MG TABLET or TELMISARTAN 40 MG TABLET or TELMISARTAN 40 MG-AMLODIPINE 10 MG TABLET or TELMISARTAN 40 MG-AMLODIPINE 5 MG TABLET or TELMISARTAN 40 MG- HYDROCHLOROTHIAZIDE 12.5 MG TABLET or TELMISARTAN 80 MG TABLET or If the patient has tried a Step 1 and a Step 2 drug, then authorization for a Step 3 drug may be given. Authorization may be given for a step 2 or step 3 angiotensin receptor blocker (ARB) or ARB-containing combination product that does not have a generic equivalent in step 1, without a trial of a step 1 or 2 agent, if the patient was recently hospitalized and discharged within the previous 30 days for a cardiovascular event (eg, myocardial infarction, hypertensive emergency, decompensated heart failure) and has already been started and stabilized on the requested agent. Page 3

4 TELMISARTAN 80 MG-AMLODIPINE 10 MG TABLET or TELMISARTAN 80 MG- AMLODIPINE 5 MG TABLET or TELMISARTAN 80 MG- HYDROCHLOROTHIAZIDE 12.5 MG TABLET or TELMISARTAN 80 MG- HYDROCHLOROTHIAZIDE 25 MG TABLET or VALSARTAN 160 MG TABLET or VALSARTAN 160 MG-HYDROCHLOROTHIAZIDE 12.5 MG TABLET or VALSARTAN 160 MG-HYDROCHLOROTHIAZIDE 25 MG TABLET or VALSARTAN 320 MG TABLET or VALSARTAN 320 MG- HYDROCHLOROTHIAZIDE 12.5 MG TABLET or VALSARTAN 320 MG- HYDROCHLOROTHIAZIDE 25 MG TABLET or VALSARTAN 40 MG TABLET or VALSARTAN 80 MG TABLET or VALSARTAN 80 MG- HYDROCHLOROTHIAZIDE 12.5 MG TABLET enhanced arb Step-2: AZOR 10 MG-20 MG TABLET or AZOR 10 MG-40 MG TABLET or AZOR 5 MG-20 MG TABLET or AZOR 5 MG-40 MG TABLET or BENICAR 20 MG TABLET or BENICAR 40 MG TABLET or BENICAR 5 MG TABLET or BENICAR HCT 20 MG-12.5 MG TABLET or BENICAR HCT 40 MG-12.5 MG TABLET or BENICAR HCT 40 MG-25 MG TABLET or TRIBENZOR 20 MG-5 MG-12.5 MG TABLET or TRIBENZOR 40 MG-10 MG-12.5 MG TABLET or TRIBENZOR 40 MG- 10 MG-25 MG TABLET or TRIBENZOR 40 MG-5 MG-12.5 MG TABLET or TRIBENZOR 40 MG-5 MG-25 MG TABLET Step-3: EDARBI 40 MG TABLET or EDARBI 80 MG TABLET or EDARBYCLOR 40 MG-12.5 MG TABLET or EDARBYCLOR 40 MG-25 MG TABLET Page 4

5 high risk medications - sedative hypnotics Step-1: ROZEREM 8 MG TABLET or TRAZODONE 100 MG TABLET or TRAZODONE 150 MG TABLET or TRAZODONE 300 MG TABLET or TRAZODONE 50 MG TABLET Step-2: ESZOPICLONE 1 MG TABLET or ESZOPICLONE 2 MG TABLET or ESZOPICLONE 3 MG TABLET or ZALEPLON 10 MG CAPSULE or ZALEPLON 5 MG CAPSULE or ZOLPIDEM 10 MG TABLET or ZOLPIDEM 5 MG TABLET or ZOLPIDEM ER 12.5 MG TABLET,EXTENDED RELEASE,MULTIPHASE or ZOLPIDEM ER 6.25 MG TABLET,EXTENDED RELEASE,MULTIPHASE This step therapy program applies to chronic utilizers greater than 64 years of age only. Authorization for zolpidem or zolpidem Er (brand or generic) may be given if being used for neuroleptic induced parkinsonism, dystonia, restless leg syndrome, or supranuclear paralysis. Authorization for a step 2 drug may be given in patients aged less than 65 years. ophthalmic prostaglandins-pst Step-1: BIMATOPROST 0.03 % EYE DROPS or LATANOPROST % EYE DROPS or LUMIGAN 0.01 % EYE DROPS or TRAVATAN Z % EYE DROPS or TRAVOPROST (BENZALKONIUM) % EYE DROPS Step-2: ZIOPTAN (PF) % EYE DROPS IN A DROPPERETTE Authorization for Zioptan may be given if the patient has a known benzalkonium chloride (BAK) sensitivity or a known sensitivity to other ophthalmic preservatives. Page 5

6 oral bisphosphonates Step-1: ALENDRONATE 10 MG TABLET or ALENDRONATE 35 MG TABLET or ALENDRONATE 40 MG TABLET or ALENDRONATE 5 MG TABLET or ALENDRONATE 70 MG TABLET or ALENDRONATE 70 MG/75 ML ORAL SOLUTION or IBANDRONATE 150 MG TABLET or RISEDRONATE 150 MG TABLET or RISEDRONATE 30 MG TABLET or RISEDRONATE 35 MG TABLET or RISEDRONATE 35 MG TABLET (12 PACK) or RISEDRONATE 35 MG TABLET (4 PACK) or RISEDRONATE 35 MG TABLET,DELAYED RELEASE or RISEDRONATE 5 MG TABLET Step-2: FOSAMAX PLUS D 70 MG-2,800 UNIT TABLET or FOSAMAX PLUS D 70 MG-5,600 UNIT TABLET rapid-acting insulin-pst Step-1: HUMALOG 100 UNIT/ML SUBCUTANEOUS CARTRIDGE or HUMALOG 100 UNIT/ML SUBCUTANEOUS SOLUTION or HUMALOG 100 UNIT/ML SUBCUTANEOUS SOLUTION (PREFILLED SYRINGE) or HUMALOG KWIKPEN 100 UNIT/ML SUBCUTANEOUS or HUMALOG KWIKPEN 200 UNIT/ML (3 ML) SUBCUTANEOUS or HUMALOG MIX UNIT/ML SUBCUTANEOUS SUSPENSION or HUMALOG MIX KWIKPEN 100 UNIT/ML SUBCUTANEOUS PEN or HUMALOG MIX UNIT/ML SUBCUTANEOUS SUSPENSION or HUMALOG MIX KWIKPEN 100 UNIT/ML SUBCUTANEOUS INSULIN PEN Step-2: APIDRA 100 UNIT/ML SUBCUTANEOUS SOLUTION or APIDRA SOLOSTAR 100 UNIT/ML SUBCUTANEOUS INSULIN PEN Page 6

7 topical actinic keratosis-pst Step-1: CARAC 0.5 % TOPICAL CREAM or DICLOFENAC 3 % TOPICAL GEL or FLUOROURACIL 2 % TOPICAL SOLUTION or FLUOROURACIL 5 % TOPICAL CREAM or FLUOROURACIL 5 % TOPICAL SOLUTION or IMIQUIMOD 5 % TOPICAL CREAM PACKET Step-2: FLUOROURACIL 0.5 % TOPICAL CREAM or ZYCLARA 2.5 % TOPICAL CREAM PUMP or ZYCLARA 3.75 % TOPICAL CREAM PACKET uloric Step-1: ALLOPURINOL 100 MG TABLET or ALLOPURINOL 300 MG TABLET Step-2: ULORIC 40 MG TABLET or ULORIC 80 MG TABLET Authorization may be given for Uloric if the patient has renal insufficiency or decreased renal function. Authorization may be given for Uloric if the patient is receiving concomitant medications that have significant drug-drug interactions with allopurinol, which are not noted with Uloric (eg, cyclosporine, chlorpropamide). Page 7

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