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1 conferenceseries LLC Ltd 10 th Annual Congress on Rare Diseases and Orphan Drugs September 23-24, 2019 Toronto Canada Invitation Conference Series LLC ltd welcomes you to attend the 10 th Annual Congress on Rare Diseases and Orphan Drugs, which is going to be held in Toronto, Canada during September 23-24, We cordially invite all the participants who are interested in sharing their knowledge and research in the arena of Rare Diseases and Orphan Drugs. Rare Diseases 2019 anticipates the participants around the globe with thought provoking Keynote lectures, Oral Presentations and Poster Presentations. Young researcher s forum. The attending delegates include Editorial Board Members of related Conference Series Ltd Journals. This is an excellent opportunity for the delegates from Universities and Institutes to interact with the world class Scientists. The intending participants can confirm their participation by registering for the conference along with your colleagues. The main theme of the conference is The voice of rare diseases - advances in research and treatment. Strike the iron when it is hot. Make your space to attend the Conference to network with your peers, exchange expertise and experiences, and arm yourself with the latest information. Regards, Rare Diseases 2019 Operating Committee

2 Rare Diseases 2019 Past Keynote Rare Diseases Conferences Alastair Kent Genetic Alliance UK Alba Ancochea EUORDIS Spain Michael S Wolfe University of Kansas USA Mark Landiak Corporate Dynamics, Inc. USA Jason Wan National Institutes of Health USA Dana Mauro National Ataxia Foundation, USA Kei Kishimoto Selecta Biosciences USA Jessica E. Foley Gaia Regulatory Sciences, USA Fernando Ferrer Multinational Partnerships LLC, USA Irene Tan Temple School of medicine USA We would like to convey our sincere thanks to our previous conferences moderator Jianmeng Chen, Food and Drug Administration, USA

3 Speaker Session I (11:30-13:00) Speaker Session II (13:00-16:00) Speaker Session III (16:00-18:00) Speaker Session I (11:30-13:00) Speaker Session II (13:00-16:00) Speaker Session III (16:00-18:00) Tentative Program Day 1 September 23, 2019 Opening Ceremony Plenary & Keynote Speeches (09:00-11:30) Networking and Refreshments Break Group Photo Different types of Rare Diseases Clinical Research and Public Awareness Mystery Diagnosis of Rare Diseases Panel Discussion Lunch Break Challenges in Rare Diseases Treatment Rare Infectious Diseases and Immune Deficiencies Rare Diseases in Cancer Panel Discussion Networking and Refreshments Break Rare Diseases in Aging Orphan Drugs- development trends and strategies Orphan Drugs and Ethical Issues Panel Discussion Day 2 September 24, 2019 Opening Ceremony Plenary & Keynote Speeches (09:00-11:30) Networking and Refreshments Break Clinical Research on Orphan Drugs Orphan Drugs and Ethical Issues Future Hereditary of Rare Diseases and Orphan Drugs Entrepreneurs Investment Meet Panel Discussion Lunch Break Different types of Rare Diseases Mystery Diagnosis of Rare Diseases Patient organizations and their role in drug development or clinical research Panel Discussion Networking and Refreshments Break Poster Presentations Best Poster Award Distribution September 23-24, 2019 Toronto, Canada Rare Diseases 2019 is happy to offer exclusive services Provide technical assistance in your research by experienced scientific advisor. Hands on training to your research team in any domain (Depends on the availability and possibility) Conducting recruitment drive at our conference venues. Post Conference networking with experts in your interested field. Creating a platform for science and student exchange programs. Making official MOU`s with selected Universities and Industries. Promotion of your organization logo and profile in our conference website and souvenir as associating partners 24X7 Research enquiries and discussions with experts as per requirement For any queries, please contact Program Manager E: rarediseases@conferenceseries.net Important Dates Abstract submission opens : September 29, 2018 Registration opens : September 29, 2018 Early bird registration : December 25, 2018 On spot registration : September 23, 2019 Previous Conferences Scientific Program scientific-program Supporting Journals Journal of Genetic Syndromes & Gene Therapy Journal of Neurological Disorders Journal of Developing Drugs

4 Rare Diseases 2019 Things to know before submission of abstract Submission of an abstract implies that the work described has not been published before and that it is not under consideration for any conference elsewhere. Abstract submitted must be prior approved by all the co-authors before submitting to the conference. Authors should strictly adhere to the authorship criteria. Each abstract will receive a Digital Object Identification Number (DOI) provided by Cross Ref. All the accepted abstracts will be published in conference proceedings which are to be distributed on the day of conference. All accepted abstracts will be published in International journals as supplementary materials. Why Conference series LLC Ltd Interactive webinars, workshops and video presentations for selective speakers on the day of the conference. National and International workshops can be co-organized at your University with collaboration with Conference Series LLC Ltd making you world exposure. Unique speaker and abstract pages will be created in Google to make your profile worldwide visibility. Supporting fair and timely review process with the valuable inputs and from the responsible reviewers. abstract-submission.php

5 September 23-24, 2019 Toronto Canada Market Analysis Importance and Scope A rare/orphan disease is outlined as a condition that affects fewer than 200,000 people. This definition was created by Congress within the Orphan Drug Act of There may be as many as 7,000 rare diseases and 70% of them have no form of treatment. Regulatory edges like longer market exclusivity, breakthrough designations, reduced fees and tax incentives are all encouraging investment. However, the marketing process and lifecycle for a rare disease drug are very different to a mass market product and require particular skills and knowledge. Rare Diseases 2019 will be the best platform for all the doctors, researchers, renowned Scientists, research scholars, students who are working in this field across the globe under a single roof to exchange their knowledge related to Rare Diseases and Orphan Drugs. This international event is an effort to find an alternative for invasive imaging technique against rare diseases like Zellweger syndrome, Muscular Dystrophy, Alkaptonuria, Angelman syndrome, Prader-Willi syndrome, Tay Sachs disease, Fragile X syndrome, Gaucher disease as well as many others. Target Audience Join the Rare Diseases and Orphan Drugs Congress to keep up to date with the industry and to learn from our expert speaker panel, bringing you important new case studies and reports on this year s relevant topics. Directors, Board Members, Presidents, Vice Presidents, Deans and Head of the Departments Researchers, Scientists, Faculties, Students Rare Diseases Associations and Societies Medical Colleges Industrial delegates from Academia and Research Industrial professionals from biomedical companies and healthcare sectors Medical Devices Manufacturing Companies Drug Manufacturing Companies and Industries Laboratory Technicians and Diagnostic Companies Business Entrepreneurs and Industrialists

6 September 23-24, 2019 Toronto Canada Major sessions Different types of Rare Diseases Clinical Research and Public Awareness Mystery Diagnosis of Rare Diseases Challenges in Rare Diseases Treatment Rare Infectious Diseases and Immune Deficiencies Rare Diseases in Cancer Rare Diseases in Aging Orphan Drugs- development trends and strategies Clinical Research on Orphan Drugs Orphan Drugs and Ethical Issues Future Hereditary of Rare Diseases and Orphan Drugs Patient organizations and their role in drug development or clinical research Entrepreneurs Investment Meet

7 Rare Diseases 2019 Membership Annual Membership Registered Member can attend upto 10 Conferences, organized by Conference Series LLC Ltd, with A Complementary Registration applicable for Package A Category. Registered Member will get up to a prestigious Annual Membership Certificate from Conference Series LLC Ltd. Registered Member can submit up to 10 abstracts of their research work for any of the 10 conferences he/she will attend. Opportunity to organize a workshop at any of our THREE Conferences. Registered Member will have his/her Affiliate Organization logo recognized on Main Backdrop Banner of the Conference. Registered Member will also receive a Complementary Networking Contact Details of all the Attendees of the Conference that he/she attends ONE Complementary Article Publication for a period of ONE YEAR in any ONE of our supporting International Journals of the Conference he/she attends. Three-Year Membership Registered Member can attend up to 33 Conferences Across the Globe, organized by Conference Series LLC Ltd, with A Complementary Registration applicable for Package A Category. Registered Member will get a a prestigious THREE YEAR MEMBERSHIP Certificate from Conference Series LLC Ltd. Registered Member can submit up to 35 abstracts of their research work for any of the 33 Conferences he/ she will attend. Opportunity to organize a workshop at at any of our 12 events. Upon his/her interest and subjected to approval from the Organizing Committee, he/she can be the prestigious Moderator for the Conference. Registered Member will have his/her Affiliate Organization logo recognized on Main Backdrop Banner of the Conference. Registered Member will also receive a Complementary Networking Contact Details of all the Attendees of the Conference that he/she attends. FOUR Complementary Article Publications for a period of THREE YEARS in any of our supporting International Journals of the Conference he/she attends. The amount can be paid in FOUR Quarterly installments during the First Year of the Membership Plan. Five-Year Membership Registered Member can attend up to 55 Conferences Across the Globe, organized by Conference Series LLC Ltd, with A Complementary Registration applicable for Package A Category. Registered Member will get a prestigious certificate for a FIVE YEAR MEMBERSHIP Certificate from Conference Series LLC Ltd. Registered Member can submit up to 60 abstracts of their research work for any of the 55 conferences he/she will attend. Opportunity to organize a workshop at any of our 25 events. Registered Member will have his/her Affiliate Organization on Main Backdrop Banner of the conference. Upon his/her interest and subjected to approval from the Organizing Committee he/she can be the prestigious Moderator and/or the Session Chair or Co-Chair for the Conference. Registered Member will also receive a Complementary Networking Contact Details of all the Attendees of the Conference that he/she attends Eight complimentary article publications for a period of five years in any supporting international journals of the Conference he/she attends EIGHT Complementary Article Publications for a period of FIVE YEARS in any of our supporting International Journals of the Conference he/she attends. The amount can be paid in FOUR Quarterly installments during the First Year of the Membership Plan. Attendees with Membership Subscriptions enjoy discounted rates and privileges. Contact Program Manager to get Membership today..!!

8 September 23-24, 2019 Toronto Canada Event Exhibitor & Conference Exhibitors Conference series LLC Ltd has stepped forward to provide more marketing and promotion for the products that are exhibited at our conferences. At each venue a group of conferences on various subjects will take place for one week designated as a ''complete event". An Exhibitor by registering for the Complete event can exhibit their products in the provided booth for whole week which helps to increase the promotion for your products where as Conference exhibitor can exhibit only for registered conference. Registration Price: 500 USD/ day includes 1 complimentary registration along with lunch, coffee breaks and 1 complimentary exhibition slot for evevt exhibitor and for Conference exhibitor 1500 USD per conference Benefits Exhibitors can avail an exposure from Academic, Business leads, Directors, CEOs, and eminent experts in various fields all over the world. The conference regular sessions will be followed by exhibition. If you are interested you can book a slot to exhibit your products at our conference. Logo recognition on Conference souvenir or booklet of abstracts. A certificate from registered conference. Promotional Video during the conference. With all other regular benefits to Exhibitors. sponsorship types Category Registration fee (USD) Elite Sponsor 5500 Silver Sponsor 3500 Gold Sponsor 4000 Young Researcher Award's Sponsor 600 Keynote Forum Sponsor 1000 Speaker Forum 1000 Program Sponsor 1000 Coffee Break Sponsor 1000 Luncheon Sponsor 2000 Pre-conference Dinner Sponsor 1000 Backdrop Sponsor 1500 Souvenir Sponsor 800 Conference Kit Sponsor 500 Podium Sponsor 500 Lanyard Sponsor 800 Add Sponsor (In Souvenir) 300 Note: The above prices are applicable for single registered conference. For any queries, please contact respective Program Manager through rarediseases@conferenceseries.net

9 Rare Diseases 2019 Venue & Accommodation Toronto, Canada Note: Our Venue & Logistics team is in communication with 2 best properties (Hotels) in Toronto and we will update the final venue information soon. For your better understanding and kind information, we recommend you to check our previous San Antonio and Boston conferences venue information listed below: Hilton San Antonio Airport 611 NW Loop 410 San Antonio Texas, USA, Crowne Plaza Newton 320 Washington Street, Newton, MA Contact Us Natalia Jones Rare Diseases Churchfield Road, London, UK, W3 6AY PH: EXT: 8039 rarediseases@conferenceseires.net About Registration Academic Only Registration: 799 USD Package A (Registration + 2 nights Accommodation): 999 USD Package B (Registration + 3 nights Accommodation): 1299 USD Business Only Registration: 899 USD Package A (Registration + 2 nights Accommodation): 1299 USD Package B (Registration + 3nights Accommodation): 1499 USD Student Student Poster: 449 USD Student Delegate: 399 USD Young Research Forum: 499 USD Others Video Presentation: 300 USD Media Partner : 100 USD Only abstract publication : 99 USD For Exhibitors Event Exhibitor: 3500 USD Conference exhibitor: 1999 USD Registration Link registration.php registration.php

10 city attractions Don't miss them in Toronto!! Aga Khan Museum Art gallery of Ontario Rogue National Park Casa Loma Resort High Park Lake Nathan Phillips Square Toronto Water Front The Beaches Royal Ontario Museum

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