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1 Charges Information Transparent charges with no hidden costs Bristol Centre for Reproductive Medicine (BCRM) Southmead Hospital, Bristol, BS10 5NB t: f: w:

2 Packages; Consultations and Ultrasound Scans Consultation Packages, Consultations and Ultrasound Scans at BCRM st consultation and ultrasound scan with Mr Akande or Ms Jefferys st consultation and ultrasound scan with Fertility consultant Follow up consultation Short follow up consultation Consultation with an Embryologist Nurse consultation Treatment support session/implications counselling (outside cycle tariff) Diagnostic Fertility Ultrasound scan (including AFC/ovarian reserve) Pregnancy ultrasound scan Cycle monitoring scan (outside cycle tariff) Failure to notify BCRM of non-attendance 75 Consultations and Scans at the SPIRE Bristol Hospital st consultation & ultrasound scan with Mr Akande Initial consultation Follow up consultation Short follow up consultation Ultrasound scan 150 Fertility tests and procedures 099 Fertility MOT package: Comprehensive consultation including Fertility ultrasound with AFC; Fertility blood tests including AMH, FSH/ LH/ Estradiol/ Prolactin/ TSH/ SHBG/ Chlamydia serology and Semen analysis Endometrial scratch Endometrial scratch under sedation Tubal test: HyCoSy Hystero Constrast Sonography and Saline Sonogram (aqua scan) Tubal test: HSG Hysterosalpingogram (X-ray test of tubes and womb cavity) Endometrial Biopsy for histology Endometrial biopsy for NK cells Saline sonogram Vaginal microscopy (HVS- CT/GC/TV PCR SWAB) Chlamydia (swab) Injection (per injection- for non BCRM registered clients) Administration fee for blood tests (for non BCRM registered clients) 50 Andrology 010 Basic semen analysis (sperm test) includes semen microscopy & MAR antibody test Advanced semen analysis - IVF/ICSI assessment includes recovery/survival & retrograde test Pre-treatment sperm check Sperm DNA fragmentation Y chromosome microdeletions Aneuploidy FISH Sperm reactive oxidative test Semen Culture Pre-treatment sperm storage 345

3 Fertility treatments 200 IUI - intrauterine insemination - natural cycle IUI intrauterine insemination - programmed cycle (excludes medication/ drugs) 750 Approximate medication charges for IUI programmed cycle IUI multiple cycles package - up to 3 programmed cycles (criteria apply-excludes drugs) HFEA licence fee per insemination cycle using DONOR sperm (DI) Use of Donor sperm per cycle of treatment (anonymous donor) Use of Donor sperm (known donor, donor screening & storage for up to 1 year) Import of donor sperm from commercial supplier (includes storage for up to 1 year) IVF in vitro fertilisation 3200 Includes patient information meeting; individual nurse planning consultation; all monitoring ultrasound scans; egg collection with general anaesthetic sedation in the care of a consultant anaesthetist; laboratory costs; sperm preparation; assisted hatching blastocyst culture EmbryoGlue the vitrification and storage of embryos/blastocysts for 1 year as applicable; Embryo/ Blastocyst transfer; pregnancy scan or follow up consultation; Treatment Support sessions including Counselling 206 ICSI + IVF -Intra-Cytoplasmic Sperm Injection procedure Includes PIM; individual nurse planning consultation; all monitoring ultrasound scans; egg collection with general anaesthetic sedation in the care of a consultant anaesthetist; laboratory costs; sperm preparation; assisted hatching blastocyst culture EmbryoGlue the vitrification and storage of embryos/blastocysts for 1 year as applicable; embryo/blastocyst transfer; pregnancy scan or follow up consultation; Treatment Support sessions including Counselling and other therapies 3995 Approximate medication charges for IVF /ICSI IVF - multiple cycles package - up to 3 cycles of IVF (fresh or frozen transfers, criteria apply and excludes drugs) Additional charge per cycle for ICSI procedure IVF planned deferred transfer cycle includes vitrification and storage of embryos/ blastocysts and 3700 embryo transfer 356 HFEA licence fee per cycle of IVF/ICSI and FET ICSI procedure (in addition to IVF cycle charge) FET Frozen embryo transfer (excluding medication) 1150 Approximate medication charges for FET IVF - egg sharing cycle - donation to unknown recipients (includes drugs and HFEA fee) 500 Egg donation treatment 212 Donor Egg Treatment IVF egg recipient cycle (includes donor eggs form unknown donor, 5800 excludes drugs) 214 Donor Egg Treatment IVF egg recipient cycle - KNOWN DONOR supplement 975 Intra-couple egg donation treatment 227 IVF - intra-couple egg donor/ recipient cycle (excluding donor & recipient drugs & donor sperm) IVF Egg sharing cycle with intra-couple egg donation and donation to unknown recipient 1450 (including all drugs & HFEA fee)

4 Other treatment, procedures and supplements 222 Ovulation Induction with FSH (per cycle) Fertility Preservation: Oocytes (egg freezing) 2500 Includes Egg collection, vitrification and storage for up to 1 year 326 Fertility Preservation: Sperm (sperm freezing) 495 Includes short consultation; recovery test, freeze and storage for up to 1 year 246 Vitrification of embryos /blastocysts with 1 year storage (patient request outside of freeze criteria) Surgical Sperm Recovery: with sedation (including up to 1 year storage) Surgical Sperm Recovery: general anaesthetic sedation (including up to 1 year storage) Egg recipient waiting list fee (refundable if wait exceeds 1 year) Embryo Transfer: Dummy Run Sedation for Embryo Transfer 300 Treatment abroad 242 To arrange blood tests & /or prescriptions (per treatment episode) To arrange prescriptions only (per treatment episode) includes 15 min consultation Fertility monitoring scan Treatment abroad package Includes up to 3 monitoring scans; 1 pregnancy scan; arranging blood tests and prescription (per treatment episode) and 15 minute consultation 650 Additional LABORATORY SERVICES EmbryoScope+ (advanced time-lapse monitoring of embryos) Free 336 EmbryoGlue Storage of embryos/blastocysts for 1 year Storage of sperm for 1 year Administration charge for the import of gametes or embryos/blastocysts from another HFEA (UK) licenced centre to BCRM 325 Administration charge for the import of sperm from a commercial provider (includes up to 1 year storage) or the import of oocyte/embryo or blastocysts/partner sperm or donor sperm from another centre outside of the UK 332 Admin/laboratory preparation charge for the export of oocyte/embryo or blastocysts/partner 250 sperm from BCRM to another fertility centre 340 Complex import /export of gametes or embryos POA 333 Preparation and hire of shipper Refundable deposit for transport shipper Free 300 None 190

5 Blood tests 060 Set 1: HB;TSH;Prolactin:FSH;LH;Rubella; Testosterone; SHBG;Oestradial Set 2: Thrombophilia Screen Set 3: Hepatitis B&C; HIV; Syphilis Set 4: FSH; LH; Oestradiol; Prolactin Set 5: Testosterone; SHBG Set 6: Thyroid Profile : T4/T3/TSH Rubella (IgG) Chlamydia serology Hepatitis B surface antigen & Hep b core antibody profile Hepatitis C Hepatitis B PCR Hepatitis C PCR Syphilis CMV HIV FSH/LH Prolactin TSH Testosterone Progesterone Oestradiol Sex Hormone Binding Globulin (SHBG) Anti-Mullerian Hormone (AMH) Haemoglobin Blood group Cystic Fibrosis screen Chromosome Analysis Thyroid antibodies DHEAS * 037 Androstenendione * 038 Electrolytes & Urea Liver function (LFT s) HTLV1 & OH progesterone * 052 Free Beta HCG serology Cortisol Ferritin Anti-cardiolipin antibodies CA ZIKA Virus serology 120 Administration fees 350 Medical Report Advice correspondence Photocopy of patient record Photocopy of patient test result ( per test) Private prescription Miscellaneous administration * 371 Miscellaneous clinical * 372 Miscellaneous laboratory *

6 Medication/ Drugs 374 Northisterone 5mg tablets Cetrotide subcutaneous injection: 0.25mgs- per syringe Cetrotide subcutaneous injection: 0.25mgs x 5 syringes Buseralin Nasal spray: 1 bottle Buseralin subcutaneous injection: 1 vial Gonal F Pen ( 25 per 75iu) 300iu Gonal F Pen 450iu Gonal F Pen 900iu Menopur: 75iu per amp Menopur: 150iu x 16 amp Menopur: 150iu per amp FET drug package ~ Ovitrelle 250mcg pen Cyclogest (progesterone) pessaries 4mg 1.40 Cyclogest pessaries x28 per cycle Cyclogest pessaries x30 per cycle 316 IM progesterone 50mgs per ml Cabergoline 0.25mg x Progynova (estradiol) 2mg tablet 25p Progynova 21 per week Oesrodial patches 100mcg each Lubion (progesterone) 25mgs per vial Clexane 20mgs Clexane 40 mgs Bemfola per 75ru Pregnyl 5000ul Gonasi 5000iu Ranitidine no charge 379 Testosterone gel tbc 380 Zoladex 3.6mg Gestone 50mg/1ml Clomiphene 50mg 383 Pregnisolone 5mgs tablets each@10p 384 Ganirelix Fyremadel 40 NOTE Delivery charge for Medication to specified address Refunds Cancelled natural cycle IUI during monitoring 230 Cancelled programmed IUI during monitoring 150 IVF cancelled before 1 st monitoring scan 2870 IVF cancelled before egg collection 1850 IVF cancelled after egg collection: no eggs retrieved 520 IVF cancelled after egg collection: failed fertilisation 320 ICSI cancelled before 1 st monitoring scan 3665 ICSI cancelled before egg collection 2645 ICSI cancelled after egg collection: no eggs retrieved 1315 ICSI cancelled after egg collection: no eggs injected 1115 ICSI cancelled after egg collection: failed fertilisation 245 FET : failed thaw 535 Please note charges may be subject to change at any time. The BCRM Finance team are pleased to take payment of the charges outlined at consultation on the day of attendance at BCRM. If in the exceptional circumstance that patients are unable to make payment at BCRM; an invoice will be raised and sent by . Payment can be made by BACS or by telephone to the Finance team. For any additional enquiries: please contact the BCRM Finance team on or finance@bcrm.org.uk

Charges Information. Transparent charges with no hidden costs

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