China Visit us at : May 11, 2011
|
|
- Louisa Mills
- 5 years ago
- Views:
Transcription
1 L(+) LACTIC ACID POLYMERS AND COPOLYMERS : STRUCTURE PROPERTY RELATIONSHIPS Dr. S. Sivaram National Chemical Laboratory, Pune , INDIA Tel : nd Federation of Asian Polymer Fax : Societies Polymer Congress, Beijing, s.sivaram@ncl.res.in China Visit us at : May 11, 2011
2 PLLA : MAJOR PROPERTY DEFICITS Slow rate of crystallization Very brittle material ; Elongation : 3-4 %, Poor heat stability Poor chain entanglement in melt state leading to poor melt viscosities CSIR Proprietary
3 PLLA PROPERTY IMPROVEMENTS : APPROACHES Poor rate of crystallization Annealing and cold crystallization Nucleation Poor Elongation Plasticization Copolymerization Increase Tm Stereocomplexation Copolymerization Nanocomposites and blends Increase melt viscosity Crosslinking Branching
4 SYNTHESIS OF POLY (L+) LACTIC ACID)S FROM L(+) LACTIC ACID
5 POLY(L+) (LACTIC ACID)S (PLLA) : PREPARATION L-Lactic acid Dehydro-polycondensation Poly(L-Lactic acid) oligomers Poly(L-Lactic acid) s Ring opening polymerization Depolymerization & cyclization L-lactide 95% yield, mp =94 o C Optical purity 100%
6 CRUDE L(+) LACTIDE FORMATION SUGAR CANE FERMENTATION OF SUGAR CANE JUICE TO L(+) LA ROP L(+) LACTIDE CRYSTALS L(+) LACTIDE CRYSTALLIZATION
7 LABORATORY POLYMERIZATION SET -UP Polycondensation set up doubled up to do distillation. SS reactor of 200mL / 800 ml. Electrical heating and overhead stirring. Ability to purge, pull vacuum, add additives. Nozzle at bottom to extrude polymer melt coupled with a pelletizer.
8 PREPARATION OF L(+) LA OLIGOMER VIA DEHYDRO- POLYCONDENSATION O Lactic acid : 600 g (90% aqueous solution) Conditions : 150 o C/N 2 /2h, 150 o C/100 mm, Hg/1.5h, 150 o C/30 mm, Hg/1.5h, 150 o C/0.005 mm, Hg/1h H O n OH Source Yield (%) Mn* (g/mol) Mw* (g/mol) PDI PURAC NCL * Determined by GPC in chloroform Under these conditions only linear oligomers are obtained with no cyclic oligomers ( MALDI-TOF)
9 PREPARATION OF DILACTIDE VIA DEPOLYMERIZATION AND CYCLIZATION) O O Lactic acid oligomer : 493 g; Catalyst : Tin powder (<150 µm) Conditions : 160 o C/N 2 /1h, 180 o C/100 mm, Hg/1h, 190 o C/10 mm, Hg/1h, 200 o C/0.01 mm, Hg/2h O O Expt. No. Tin Powder (wt%) LactideYield Optical Purity (%) (L+)(%) 1 ( >150 µm) 6 (>150 µm) L(+) LACTIDE AS FORMED UNSUITABLE FOR POLYMERIZATION: PURIFIED BY CRYSTALLIZATION FROM MELT :
10 PROTON NMR OF CRUDE L(+)LACTIDE PURIFICATION O NCL O O O PURAC O O O O
11 PROTON NMR OF CRYSTALLIZED L(+) LACTIDE NCL O O O O PURAC O O O O
12 PREPARATION OF POLY(LACTIC ACID)S via RING OPENING POLYMERIZATION Catalyst concentration: 0.03% to 0.05 wt% Chain stopper : Lauryl alcohol Temperature: 180 o C Expt. No. Chain Stopper (wt%) Time Mn a Mw a (min) (g/mol) (g/mol) PDI
13 ISOSORBIDE AS A COMONOMER
14 ISOSORBIDE MONOMER Dihydrohexitols - byproducts of biomass - prepared from starch, chiral in nature - thermally stable Monomer for biodegradable polymers - improved accessibility of two -OH groups - exo substituent increases ring thermal stability Polymers presented promising properties - high glass transitions - excellent thermal stabilities - interesting physical properties Isosorbide copolyesters - relatively high Tg s - cholesteric phase formation HO O H H O OH
15 ISOSORBIDE: A PLATFORM CHEMICAL
16 L(+) LA- ISOSORBIDE COPOLYMER Incorporation of isosorbide into PLLA by melt/solution disproportionation followed by solid state polymerization
17 L(+) LA-ISOSORBIDE COPOLYMER VIA MELT DISPROPORTIONATION PLLA : 10 g (IV : 1.6 dl/g; Mw: 160,000 g/mol) Catalyst : Titanium isopropoxide Catalyst conc.: 0.5 wt% (based on PLA) PLLA (wt%) Isosorbide (wt%) Temp. ( o C) Time (h) IV* (dl/g) * Determined in chloroform at 30 o C by Ubbelhode viscometer.
18 DISPROPORTIONATED L(+)LA-ISOSORBIDE COPOLYMER Sample ID PLA:ISB Ratio IV (dl/g) T m (ºC) T c (ºC) T g (ºC) H f (J/g) H c (J/g) PLAISB1 98: PLAISB2 94: PLAISB3 90: IV was determined in Chloroform at 30 o C by Ubbelhode viscometer Tg, Tm, Tc were determined by Q10 DSC (TA Instruments).
19 L(+) LA-ISOSORBIDE COPOLYMER VIA SOLUTION DISPROPORTIONATION PLLA : 10 g (IV : 1.6 dl/g; Mw: 160, 000 g/mol) Solvent : Chloroform Catalyst : Titanium isopropoxide Catalyst conc.: 0.5 wt% (based on PLA) PLLA (wt%) ISB (wt%) Temp. ( o C) Time (h) Incorp. (%) Yield (%) IV* (dl/g) * Determined in chloroform at 30 o C by Ubbelhode viscometer.
20 DISPROPORTIONATED L(+)LA-ISOSORBIDE COPOLYMER Sample ID PLA:ISB Ratio IV (dl/g) T m (ºC) T c (ºC) T g (ºC) H f (J/g) PLAISB4 90: PLAISB6 70: IV was determined in Chloroform at 30 o C by Ubbelhode viscometer Tg, Tm, Tc were determined by Q10 DSC (TA Instruments).
21 H NMR SPECTRA OF ISOSORBIDE IN CDCL Fig. 2
22 1 H NMR SPECTRA OF PLA-ISOSORBIDE COPOLYMER IN CDCL ,5 3,8 7, ,5 3,8 7, δ ppm
23 1 H NMR SPECTRA OF PLA-ISOSORBIDE COPOLYMER IN CDCL
24 SOLID STATE POLYMERIZATION OF DISPROPORTIONATED L(+) LA-ISOSORBIDE COPOLYMER Polymn Steps Sample ID IV (dl/g) T g ( C) T m ( C) T c ( C) H f (W/g) H c (W/g) 1 PLAISB BSSP 100 C/1h ASSP 120 C/2h ASSP 135 C/3h ASSP 145 C/2h ASSP 155 C/2h IV was determined in Chloroform at 30 o C by Ubbelhode viscometer Tg, Tm, Tc were determined by Q10 DSC (TA Instruments).
25 :DSC THERMOGRAMS OF PLA-ISOSORBIDE COPOLYMER DURING SSP Step-6 /g) Heat flow (W/ Step-5 Step-1 S tep-3 S tep Tem perature ( o C ) Fig. 9
26 12-HYDROXY STEARIC ACID AS COMONOMER
27 HO CH 3 O CH C OH + HO CH (CH 2 ) 11 COOH ( CH 2 ) 5 CH 3 O H O CH C O m CH 3 Sn Catalyst CH (CH 2 ) 11 ( CH 2 ) 5 O C OH n COPOLYMERS OF L (+) - LACTIC ACID WITH 12-HYDROXY STEARIC ACID CH 3
28 PROPERTIES OF L(+) LA 12- HSA COPOLYMERS mol% PLA mol% 12-HSA Feed Product T g ( C) T m ( C) M n (VPO) , , , NIL ,320
29 BRANCHING/CROSSLINKING USING STYRENE GMA COPOLYMER
30 SYNTHESIS OF STYRENE-GMA COPOLYMER Sty (%) GMA (%) IV a (dl/g) Mn b (g/mol) Mw b (g/mol) PDI Copolymer Comp c Sty (%) GMA (%) Epoxy eq d (g/mol) a Determined by Ubbelhode viscometer in chloroform at 30 o C. b Determined by gel permeation chromatography using chloroform solvent. c Determined by 1 H NMR spectroscopy. d Determined by titrimetry.
31 MELT COMPOUNDING AND RHEOLOGICAL MEASUREMENTS Temp. : 180 o C, Residence Time : 3 min in nitrogen Speed : 100 rpm ARES RHEOMETER DSM MICROCOMPOUNDER
32 MELT COMPOUNDING OF STYRENE- GMA COPOLYMER WITH PLLA Polymer Code Sty:GMA (Comp.) PLA (%) St-GMA (%) Mn a (g/mol) Mw a (g/mol) PLLA PLLA :50 PLLA PLLA3 40: PLLA PLLA5 30: PLLA PLLA7 20: PLLA a Determined by gel permeation chromatography using chloroform solvent. PDI
33 STORAGE MODULUS AND COMPLEX VISCOSITY OF PLLA- GMA BLENDS Addition of 2 % GMA enhances melt viscosity of PLLA
34 SUMMARY Tm improved using isosorbide as comonomer Tg decreased using 12- hydroxystearic acid as comonomer Branching and crosslinking with S-GMA copolymer improves melt viscosity of PLLA
35 THANK YOU
36 SYNTHESIS OF PLLA OLIGOMERS CONTROLLED END GROUPS Controlled ROP of purified LL-dilactide performed 120 C/ 12 h H Oct 2 Sn O R O O O ROCO(CH 3 )OCOCH(CH H 3 )O SnOct 2 O R = H, WATER used as initiator to get carboxylic acid end groups M n = ([M] / [I]) x M Lactide x conversion % and DP n = ([M] / [I]) x conversion %
37 MOLECULAR WEIGHT DETERMIATION OF PLLA SAMPLES Number average molecular weights of the PLA oligomers synthesized by ROP of L-lactide with water as co-initiator and Sn(Oct) 2 as initiator. PLA sample [Lactide]/ [Sn(Oct) 2 ] [Lactide]/ [H 2 O] Conv. (%) DP n, Calc DP n, NMR M n, NMR M n, VPO Fig. 3.1: 13C-NMR spectrum (500 MHz) of PLLA oligomer3.1 synthesized by ROP : Inset showing ester carbonyl region (ester as well as carboxylic acid)
38 DSC OF PLA OLIGOMERS HAVING HYDROXYLA AND CARBOXY END GROUPS PLA samples T g ( C) T m ( C) H melt ing (J.g -1 ) % Crystallinity from powder XRD Fig. 3.2: Thermal characterization(dsc) first and second heating showing Tm and Tg, respectively of PLA oligomers: (a) 3.1, first heating; (b) 3.2, first heating; (c) 3.1, second heating and (d) 3.2, second heating
Figure S7: ATR FTIR spectra of enantiomeric UP-PLA-UPy and sc-upy-pla-upy. Figure S9: SEM microphotographs sc-upy-pla-oh in 1,4-dioxane and chloroform
Supporting Information for Macromolecules, DOI: Supramolecular Polylactides by the Cooperative Interaction of the End Groups and Stereocomplexation By M. Brzeziński*, T. Biela Table of Contents Figure
More informationAccessory Publication
10.1071/CH09088_AC CSIRO 2009 Accessory Publication: Australian Journal of Chemistry, 2009, 62(8), 790 793 Thermally Responsive Elastomeric Supramolecular Polymers Featuring Flexible Aliphatic Hydrogen
More informationPlasticization of poly (L-lactide) bioplastic films with poly (propylene glycol)-b-oligo ( -caprolactone)
International Journal of Applied Chemistry. ISSN 0973-1792 Volume 12, Number 3 (2016) pp. 309-322 Research India Publications http://www.ripublication.com Plasticization of poly (L-lactide) bioplastic
More informationSynthesis and Evaluation of Esterified Estolide
Chapter 5 Synthesis and Evaluation of Esterified Estolide 5.1 Introduction Coconut oil has a very high congelation temperature precluding its use as base oil for industrial lubricants in temperate and
More informationSTARCH-G-PLA IN ONE POT PROCESS: THE USE AS A COMPATIBILIZER FOR PLA/TPS BLENDS AND THE DEVELOPMENT OF EXTERNAL STIMULI RESPONSIVE FIBER
STARCH-G-PLA IN ONE POT PROCESS: THE USE AS A COMPATIBILIZER FOR PLA/TPS BLENDS AND THE DEVELOPMENT OF EXTERNAL STIMULI RESPONSIVE FIBER Nathapol Chinivirojsatian a, Autchara Pangon c, Suwabun Chirachanchai*
More informationElectronic Supplementary Material
Electronic Supplementary Material PAMAM Dendrimers Bearing Electron-Donating Chromophores: Fluorescence and Electrochemical Properties Bing-BingWang a, Xin Zhang a, Ling Yang a, Xin-Ru Jia* a, Yan Ji a,
More information3 CHAPTER 3: RESULTS AND DISCUSSION SYNTHESIS OF PALM OLEIC ACID-BASED MACROMERS
3 CHAPTER 3: RESULTS AND DISCUSSION SYNTHESIS OF PALM OLEIC ACID-BASED MACROMERS In view of the increasing interest in environmental protection, the use of vegetable oils in non-food applications has attracted
More informationSupporting Information. Enzymatic synthesis of electrospinnable poly(butylene succinate-co-dilinoleic. succinate) thermoplastic elastomer
Electronic Supplementary Material (ESI) for RSC Advances. This journal is The Royal Society of Chemistry 2017 Supporting Information Enzymatic synthesis of electrospinnable poly(butylene succinate-co-dilinoleic
More informationAuto-assemblage de copolymères à blocs amphiphiles Suming LI
Auto-assemblage de copolymères à blocs amphiphiles Suming LI Institut Européen des Membranes Université de Montpellier 34095 Montpellier, France Self-assembly of amphiphilic block copolymers Colloidal
More informationSynthesis of Polyesters from Azelaic Acid and Glycerol by Polycondensation Reaction
Synthesis of Polyesters from Azelaic Acid and Glycerol by Polycondensation Reaction Thitipat Chongcharoenchaikul 1, Patchanita Thamyongkit 2 and Sirilux Poompradub 1* 1 Department of Chemical Technology,
More informationMaintaining Structural Stability of Poly(lactic acid): Effects of Multifunctional Epoxy based Reactive Oligomers
Polymers 214, 6, 1232-125; doi:1.339/polym641232 Article OPEN ACCESS polymers ISSN 273-436 www.mdpi.com/journal/polymers Maintaining Structural Stability of Poly(lactic acid): Effects of Multifunctional
More informationDual-Responsive Polymer Micelles for. Target-Cell-Specific Anticancer Drug Delivery
Dual-Responsive Polymer Micelles for Target-Cell-Specific Anticancer Drug Delivery Xing Guo, Chunli Shi, Guang Yang, Jie Wang, Zhenghong Cai, and Shaobing Zhou,, * Key Laboratory of Advanced Technologies
More informationA pillar[2]arene[3]hydroquinone which can self-assemble to a molecular zipper in the solid state
A pillar[2]arene[3]hydroquinone which can self-assemble to a molecular zipper in the solid state Mingguang Pan, Min Xue* Department of Chemistry, Zhejiang University, Hangzhou 310027, P. R. China Fax:
More informationCHAPTER 3 REACTIONS BETWEEN EPOXIDIZED NATURAL RUBBER AND PALM OIL-BASED ALKYDS
CHAPTER 3 REACTIONS BETWEEN EPOXIDIZED NATURAL RUBBER AND PALM OIL-BASED ALKYDS Alkyds are polyfunctional vegetable oil-modified polyesters, produced through esterification reaction between the natural
More informationSYNTHESIS OF REACTIVE SOYBEAN OILS FOR USE AS BIOBASED THERMOSET RESINS IN STRUCTURAL NATURAL FIBRE COMPOSITES
SYNTHESIS F REACTIVE SYBEAN ILS FR USE AS BIBASED THERMSET RESINS IN STRUCTURAL NATURAL FIBRE CMPSITES Kayode Adekunle, Dan Åkesson and Mikael Skrifvars School of Engineering University College of Borås
More informationSynthesis of Sequence-Controlled Acrylate Oligomers. via Consecutive RAFT Monomers Additions
Supporting Information Synthesis of Sequence-Controlled Acrylate ligomers via Consecutive RAFT Monomers Additions Joke Vandenbergh a, Gunther Reekmans, b Peter Adriaensens b and Thomas Junkers a * a Polymer
More informationConversion of Glycerol into Polyhydroxybutyrate(PHB)UsingEscherichia coli
Conversion of Glycerol into Polyhydroxybutyrate(PHB)UsingEscherichia coli Endah Fitriani Rahayu a, Wega Trisunaryanti b, Karna Wijaya b Abstract Conversion of glycerol into polyhydroxybutyrate (PHB) usingescherichia
More informationph Switchable and Fluorescent Ratiometric Squarylium Indocyanine Dyes as Extremely Alkaline Sensors
ph Switchable and Fluorescent Ratiometric Squarylium Indocyanine Dyes as Extremely Alkaline Sensors Jie Li, Chendong Ji, Wantai Yang, Meizhen Yin* State Key Laboratory of Chemical Resource Engineering,
More informationYUAN LI A.PROF QIZHI CHEN, PROF WAYNE COOK
Synthesis, characterization and properties of biocompatible poly(glycerol sebacate) YUAN LI A.PROF QIZHI CHEN, PROF WAYNE COOK Background Demand of biomaterials in the field of soft tissue engineering
More informationSupporting Information
Supporting Information Polymer Micelles Stabilization-n-Demand through Reversible Photocrosslinking 1. Synthesis and Characterization of Diblock Copolymers Materials. Cu(I)Br, 2-Bromo-2-methylpropionyl
More informationSupporting Information. Transformation of Framework Solids into Processible Metallo-polymers
Supporting Information Transformation of Framework Solids into Processible Metallo-polymers Eun-Young Choi, Chunji Gao, Hong-Jun Lee, O-Pil Kwon*, Suck-Hyun Lee* Department of Molecular Science and Technology,
More informationMasatoshi Shibuya,Takahisa Sato, Masaki Tomizawa, and Yoshiharu Iwabuchi* Department of Organic Chemistry, Graduate School of Pharmaceutical Sciences,
Oxoammonium ion/naclo 2 : An Expedient, Catalytic System for One-pot Oxidation of Primary Alcohols to Carboxylic Acid with Broad Substrate Applicability Masatoshi Shibuya,Takahisa Sato, Masaki Tomizawa,
More informationSynthesis and Characterization of Certain Biodegradable Random Aliphatic Copolyesters
Asian Journal of Chemistry; Vol. 23, No. 2 (211), 556-56 Synthesis and Characterization of Certain Biodegradable Random Aliphatic Copolyesters A. RAVI 1,*, R. NANTHINI 2, M. KARUNANIDHI 3 and V. JAISANKAR
More informationTuning the Degradation Profiles of Poly(L lactide)-based Materials through Miscibility
pubs.acs.org/biomac Terms of Use Tuning the Degradation Profiles of Poly(L lactide)-based Materials through Miscibility Veluska Arias, Anders Ho glund, Karin Odelius, and Ann-Christine Albertsson* Department
More informationShape Memory Acrylate Polymers Enabled by Radiation Crosslinking
Shape Memory Acrylate Polymers Enabled by Radiation Crosslinking Kejia Yang, Hongbo Fan 2, Wyatt Archer, Benjamin Lund 3, Walter Voit,2,3 The University of Texas at Dallas, Department of Chemistry and
More informationEnantioselective synthesis of anti- and syn-β-hydroxy-α-phenyl carboxylates via boron-mediated asymmetric aldol reaction
Enantioselective synthesis of anti- and syn-β-hydroxy-α-phenyl carboxylates via boron-mediated asymmetric aldol reaction P. Veeraraghavan Ramachandran* and Prem B. Chanda Department of Chemistry, Purdue
More informationPART I: SYNTHESIS OF AROMATIC POLYKETONES VIA SOLUBLE PRECURSORS DERIVED FROM BIS(α-AMINONITRILE)S
PART I: SYNTHESIS OF AROMATIC POLYKETONES VIA SOLUBLE PRECURSORS DERIVED FROM BIS(α-AMINONITRILE)S PART II: MODIFICATIONS OF EPOXY RESINS WITH FUNCTIONAL HYPERBRANCHED POLY(ARYLENE ESTER)S by Jinlian Yang
More informationSynthesis and Blastocyst Implantation Inhibition Potential of Lupeol Derivatives in Female Mice
Supporting Information Rec. Nat. Prod. 9:4 (2015) 561-566 Synthesis and Blastocyst Implantation Inhibition Potential of Lupeol Derivatives in Female Mice Anita Mahapatra 1*, Purvi Shah 1, Mehul Jivrajani
More informationSupporting information
S1 Supporting information Biodegradable Injectable Polymer Systems Exhibiting Temperature-Responsive Irreversible Sol-to-Gel Transition by Covalent Bond Formation Yasuyuki YOSHIDA 1,2, Keisuke KAWAHARA
More informationSupplementary Figure S1. SEC trace of polymerization of Methyl acrylate (MA) with a high initiator to monomer ratio (1:4) via in situ DE-ATRP (30% AA
Supplementary Figure S1. SEC trace of polymerization of Methyl acrylate (MA) with a high initiator to monomer ratio (1:4) via in situ DE-ATRP (30% AA of Cu II ). The result shows a characteristic of living
More informationEUDRAGIT L 100 and EUDRAGIT S 100
Technical Information EUDRAGIT L 100 and EUDRAGIT S 100 Specification and Test Methods Ph. Eur. Methacrylic Acid - Methyl Methacrylate Copolymer (1:1) Methacrylic Acid - Methyl Methacrylate Copolymer (1:2)
More informationSupporting Information for. Boronic Acid Functionalized Aza-Bodipy (azabdpba) based Fluorescence Optodes for the. analysis of Glucose in Whole Blood
Supporting Information for Boronic Acid Functionalized Aza-Bodipy (azabdpba) based Fluorescence Optodes for the analysis of Glucose in Whole Blood Yueling Liu, Jingwei Zhu, Yanmei Xu, Yu Qin*, Dechen Jiang*
More informationContinuous flow retro-diels Alder reaction: an. efficient method for the preparation of pyrimidinone
Supporting Information for Continuous flow retro-diels Alder reaction: an efficient method for the preparation of pyrimidinone derivatives Imane Nekkaa 1, Márta Palkó 1, István M. Mándity 1, and Ferenc
More informationPreparation, isolation and characterization of N α -Fmoc-peptide isocyanates: Solution synthesis of oligo-α-peptidyl ureas
SUPPORTING INFORMATION Preparation, isolation and characterization of N α -Fmoc-peptide isocyanates: Solution synthesis of oligo-α-peptidyl ureas Vommina V. Suresh Babu*, Basanagoud S. Patil, and Rao Venkataramanarao
More informationL-Carnosine-Derived Fmoc-Tripeptides Forming ph- Sensitive and Proteolytically Stable Supramolecular
Supporting Information: L-Carnosine-Derived Fmoc-Tripeptides Forming ph- Sensitive and Proteolytically Stable Supramolecular Hydrogels Rita Das Mahapatra, a Joykrishna Dey* a, and Richard G. Weiss b a
More informationPhotocontrolled Interconversion of Cationic and Radical Polymerizations
Photocontrolled Interconversion of Cationic and Radical Polymerizations Veronika Kottisch, Quentin Michaudel, and Brett P. Fors* Cornell University, Ithaca, New York, 14853, United States Supporting Information
More informationSupporting Information
S1 Supporting Information Assembly of Amphiphilic Hyperbranched Polymeric Ionic Liquids in Aqueous Media at Different ph and Ionic Strength Volodymyr F. Korolovych, a Petr A. Ledin, a Alexandr Stryutsky,
More informationPolychalcone derived from 8-acetoxyquinoline-5-aidehyde
Prec. Indian Acad. Sci. (Chem. Sci.), Vol. 96, No. 5, March 1986, pp. 321-326. 9 Printed in India. Polychalcone derived from 8-acetoxyquinoline-5-aidehyde H S PATEL Department of Chemistry, Sardar Patel
More informationImproving the Process Ability of Poly (3-Hydroxybutyrate) by a Polyphenolic Natural Additive
Journal of Applied Packaging Research Volume 8 Number 4 Special Issue of API 2015-Part 2 Article 1 2016 Improving the Process Ability of Poly (3-Hydroxybutyrate) by a Polyphenolic Natural Additive Maria
More informationFP7 project - SAM.SSA
Sugar Alcohol based Materials for Seasonal Storage Applications FP7 project - SAM.SSA Sugar Alcohol based Materials for Seasonal Storage Applications Workshop and Onsite Demonstration CiCenergigune Miñano,
More informationThe Synthesis of modified hydrophobic starch nanoparticles using long chain fatty acids was accomplished. The modified starch nanoparticles were
CHAPTER 4 Hydrophobic grafted and crosslinked starch nano particles for drug delivery The Synthesis of modified hydrophobic starch nanoparticles using long chain fatty acids was accomplished. The modified
More informationStereoselective Aza-Darzens Reactions of Tert- Butanesulfinimines: Convenient Access to Chiral Aziridines
Stereoselective Aza-Darzens Reactions of Tert- Butanesulfinimines: Convenient Access to Chiral Aziridines Toni Moragas Solá, a Ian Churcher, b William Lewis a and Robert A. Stockman* a Supplementary Information
More informationHomopolymers as Structure-Driving Agents in Semicrystalline Block Copolymer Micelles
Supporting information for: Homopolymers as Structure-Driving Agents in Semicrystalline Block Copolymer Micelles Georgios Rizis, Theo G. M. van de Ven*, Adi Eisenberg* Department of Chemistry, McGill University,
More informationImproved Carbonylation of Heterocyclic Chlorides and Challenging Aryl Bromides
Albaneze-Walker et al S-1 Improved Carbonylation of Heterocyclic Chlorides and Challenging Aryl Bromides Jennifer Albaneze-Walker*, Charles Bazaral, Tanya Leavey, Peter G. Dormer, and Jerry A. Murry Department
More informationBio Ionic Liquids: Room Temperature Ionic Liquids Composed Wholly of Biomaterials
SUPPORTING INFORMATION Bio Ionic Liquids: Room Temperature Ionic Liquids Composed Wholly of Biomaterials Yukinobu Fukaya a, Yoshiki Iizuka a, Kenta Sekikawa a, and Hiroyuki Ohno a * a Department of Biotechnology,
More informationChristophe Lincheneau, Bernard Jean-Denis and Thorfinnur Gunnlaugsson* Electronic Supplementary Information
Self-assembly formation of mechanically interlocked [2]- and [3]catenanes using lanthanide ion [Eu(III)] templation and ring closing metathesis reactions Christophe Lincheneau, Bernard Jean-Denis and Thorfinnur
More informationKinetics and mechanisms of the oxidation processes for unsaturated-hydrocarbon-modified scavengers
The University of Toledo The University of Toledo Digital Repository Theses and Dissertations 2010 Kinetics and mechanisms of the oxidation processes for unsaturated-hydrocarbon-modified scavengers Hao
More informationElectronic Supporting Information
Electronic Supplementary Material (ESI) for Materials Chemistry Frontiers. This journal is the Partner Organisations 2018 Electronic Supporting Information Tetraphenylpyrazine-based luminogens with full-colour
More informationDégradation et biodégradation des matériaux biorésorbables. Jean COUDANE
et biodégradation des matériaux biorésorbables Jean CUDANE Centre de Recherches sur les Biopolymères Artificiels UMR CNRS 5473 Faculté de Pharmacie, Montpellier, France jcoudane@univ-montp1.fr Sophia Antipolis
More informationConversion of furfural into cyclopentanone over Ni-Cu bimetallic catalysts
Supporting Information for Conversion of furfural into cyclopentanone over Ni-Cu bimetallic catalysts Yanliang Yang, ab Zhongtian Du, a Yizheng Huang, a Fang Lu, a Feng Wang, a Jin Gao a and Jie Xu* a
More informationSupporting Information
Electronic Supplementary Material (ESI) for ChemComm. This journal is The Royal Society of Chemistry 2018 Supporting Information Facile Three-Step Synthesis and Photophysical Properties of [8]-, [9]-,
More informationSupporting Information. for. Synthesis of 2,1-benzisoxazole-3(1H)-ones by basemediated. photochemical N O bond-forming
Supporting Information for Synthesis of 2,1-benzisoxazole-3(1H)-ones by basemediated photochemical N O bond-forming cyclization of 2-azidobenzoic acids Daria Yu. Dzhons and Andrei V. Budruev* Address:
More informationSupporting information to Amino-functional polyester dendrimers based on bis-mpa as nonviral vectors for sirna delivery
Supporting information to Amino-functional polyester dendrimers based on bis-mpa as nonviral vectors for sirna delivery P. Stenström, D. Manzanares, Y. Zhang, V. Ceña and M. Malkoch* * To whom correspondence
More informationHeparin Sodium ヘパリンナトリウム
Heparin Sodium ヘパリンナトリウム Add the following next to Description: Identification Dissolve 1 mg each of Heparin Sodium and Heparin Sodium Reference Standard for physicochemical test in 1 ml of water, and
More informationCERTIFICATE OF ANALYSIS
CERTIFICATE OF ANALYSIS Analysis Result Note: Moisture be determined before packing. Analysis Item Unit Specification Method Intrinsic Viscosity dl/g 0.64 ± 0.01 UBBELHODE DEG content %wt 1.4 ± 0.4 GC
More informationTEPZZ 5848A_T EP A1 (19) (11) EP A1 (12) EUROPEAN PATENT APPLICATION. (51) Int Cl.: C08G 63/181 ( ) C08G 63/60 (2006.
(19) TEPZZ 848A_T (11) EP 3 23 848 A1 (12) EUROPEAN PATENT APPLICATION (43) Date of publication: 2..17 Bulletin 17/43 (1) Int Cl.: C08G 63/181 (06.01) C08G 63/60 (06.01) (21) Application number: 1616818.2
More information(12) Patent Application Publication (10) Pub. No.: US 2012/ A1
(19) United States (12) Patent Application Publication (10) Pub. No.: US 2012/0196997 A1 LU et al. US 20120196997A1 (43) Pub. Date: (54) (75) (73) (21) (22) (60) COMPOSITIONS OF GLYCDYL METHACRYLATE COPOLYMER
More informationStudy on effective parameters on phase separation in Segmented polyurethanes
Proceedings of European Congress of Chemical Engineering (ECCE-6) Copenhagen, 16-20 September 2007 Study on effective parameters on phase separation in Segmented polyurethanes M. Amrollahi, G. Mir Mohamad
More informationSupporting Information. Copper-catalyzed cascade synthesis of benzimidazoquinazoline derivatives under mild condition
Supporting Information Copper-catalyzed cascade synthesis of benzimidazoquinazoline derivatives under mild condition Shan Xu, Juyou Lu and Hua Fu* Key Laboratory of Bioorganic Phosphorus Chemistry and
More informationSupplemental Information. Reactivity of Monovinyl (Meth)Acrylates Containing Cyclic Carbonates
Supplemental Information Reactivity of Monovinyl (Meth)Acrylates Containing Cyclic Carbonates Kathryn A. Berchtold a, Jun Nie b, Jeffrey W. Stansbury c, d, and Christopher N. Bowman c, d, a Materials Science
More informationCHEMICALLY MODIFIED LIGNIN A POTENTIAL RESOURCE MATERIAL FOR COMPOSITES WITH BETTER STABILITY
International Journal of Science, Environment and Technology, Vol. 4, No 1, 2015, 183 189 ISSN 2278-3687 (O) CHEMICALLY MODIFIED LIGNIN A POTENTIAL RESOURCE MATERIAL FOR COMPOSITES WITH BETTER STABILITY
More informationEngineering Green Lubricants II: Thermal Transition and Flow Properties of Vegetable Oil- Derived Diesters
Engineering Green Lubricants II: Thermal Transition and Flow Properties of Vegetable Oil- Derived Diesters Latchmi Raghunanan and Suresh S. Narine. * Trent Centre for Biomaterials Research, Departments
More informationA New Design for Light-Breakable Polymer Micelles
Supporting Information A New Design for Light-Breakable Polymer Micelles 1. Synthesis and Characterization of Diblock Copolymer Materials. Dioxane and THF were purified by distillation from sodium with
More informationSupporting Information
Supporting Information Advanced ultrafiltration membranes based on functionalized poly(arylene ether sulfone) block copolymers Mahendra Kumar and Mathias Ulbricht* Lehrstuhl für Technische Chemie II, Universität
More informationSupporting Information
Supporting Information A single design strategy for dual sensitive ph probe with a suitable range to map ph in living cells Kang-Kang Yu, Ji-Ting Hou, Kun Li, * Qian Yao, Jin Yang, Ming-Yu Wu, Yong-Mei
More informationTrans-stereospecific polymerization of butadiene and random copolymerization with styrene using borohydrido rare earths / magnesium dialkyl catalysts
Trans-stereospecific polymerization of butadiene and random copolymerization with styrene using borohydrido rare earths / magnesium dialkyl catalysts A. Ventura a, T. Chenal b,c,d,e, *, M. Bria b,f, F.
More informationSynthesis and Polymerization of Cyclobutenyl-Functionalized. Polylactide and Polycaprolactone: A Consecutive ROP/ROMP
Electronic Supplementary Material (ESI) for Polymer Chemistry. This journal is The Royal Society of Chemistry 2014 Supporting Information Synthesis and Polymerization of Cyclobutenyl-Functionalized Polylactide
More informationFOOD POLYMER SCIENCE OF STARCH STRUCTURAL ASPECT FRINGED MICELLE MODEL OF PARTIALLY CRYSTALLINE STARCH AMORPHOUS REGION GLASS TRANSITION AT Tg FUNCTIONAL ASPECT STARCH MAP CRYSTALLINE REGION MELTING TRANSITION
More informationPolydispersity control in ring opening metathesis polymerization of amphiphilic norbornene diblock copolymers
Polymer 44 (2003) 4943 4948 www.elsevier.com/locate/polymer Polydispersity control in ring opening metathesis polymerization of amphiphilic norbornene diblock copolymers Sufi R. Ahmed a, Steven E. Bullock
More informationSupporting Information
Supporting Information Wiley-VCH 2008 69451 Weinheim, Germany Supporting Information Enantioselective Cu-catalyzed 1,4-Addition of Various Grignard Reagents to Cyclohexenone using Taddol-derived Phosphine-Phosphite
More informationSupporting Information. Efficient copper-catalyzed Michael addition of acrylic derivatives with primary alcohols in the presence of base
Supporting Information Efficient copper-catalyzed Michael addition of acrylic derivatives with primary alcohols in the presence of base Feng Wang, a Haijun Yang, b Hua Fu, b,c * and Zhichao Pei a * a College
More informationDivergent Construction of Pyrazoles via Michael Addition of N-Aryl Hydrazones to 1,2-Diaza-1,3-dienes
Divergent Construction of Pyrazoles via Michael Addition of N-Aryl Hydrazones to 1,2-Diaza-1,3-dienes Serena Mantenuto, Fabio Mantellini, Gianfranco Favi,* and Orazio A. Attanasi Department of Biomolecular
More informationUnderstanding the Variables that Define Tg for Kraft Lignin
Understanding the Variables that Define Tg for Kraft Lignin Hasan Sadeghifar, Dimitris S. Argyropoulos Departments of Chemistry and Forest Biomaterials North Carolina State University Raleigh, NC USA Objective
More informationMechanochemical Modification of Lignin and Application of the Modified Lignin for Polymer Materials
Mechanochemical Modification of Lignin and Application of the Modified Lignin for Polymer Materials Jinwen Zhang Composite Materials and Engineering Center Washington State University Significance Petroleum-based
More informationSUPPORTING INFORMATION. Transition metal-promoted synthesis of 2-aryl/heteroaryl-thioquinazoline: C-S
1 SUPPORTING INFORMATION Transition metal-promoted synthesis of 2-aryl/heteroaryl-thioquinazoline: C-S Bond formation by Chan-Lam Cross-Coupling Reaction SATYA KARUNA PULAKHANDAM a, NARESH KUMAR KATARI
More informationLife s molecular diversity is based on the. properties of carbon. Chain Ring Branching chain
Carbon Compounds Life s molecular diversity is based on the properties of carbon Chain Ring Branching chain The Chemistry of Carbon : carbon based Carbon can make 4 covalent bonds The foundation of organic
More informationAllenylphosphine oxides as simple scaffolds for. phosphinoylindoles and phosphinoylisocoumarins
Supporting Information for Allenylphosphine oxides as simple scaffolds for phosphinoylindoles and phosphinoylisocoumarins G. Gangadhararao, Ramesh Kotikalapudi, M. Nagarjuna Reddy and K. C. Kumara Swamy*
More informationFATTY-ACID CAPPED OLIGOMERIC PROPANEDIOL SUCCINATES
FATTY-ACID CAPPED OLIGOMERIC PROPANEDIOL SUCCINATES Note: This research was presented at the 2016 in cosmetics exhibition in Paris on April 13, 2016. Purpose: Successfully produced propanediol succinates
More informationFacile Cu(II) mediated conjugation of thioesters and thioacids to peptides and proteins under mild conditions
Electronic Supplementary Material (ESI) for Organic & Biomolecular Chemistry. This journal is The Royal Society of Chemistry 2018 Facile Cu(II) mediated conjugation of thioesters and thioacids to peptides
More informationSupporting Information. Radical fluorination powered expedient synthesis of 3 fluorobicyclo[1.1.1]pentan 1 amine
Electronic Supplementary Material (ESI) for rganic & Biomolecular Chemistry. This journal is The Royal Society of Chemistry 2015 Supporting Information Radical fluorination powered expedient synthesis
More informationCDI Mediated Monoacylation of Symmetrical Diamines and Selective Acylation of Primary Amines of Unsymmetrical Diamines
Supporting information: CDI Mediated Monoacylation of Symmetrical Diamines and Selective Acylation of Primary Amines of Unsymmetrical Diamines Sanjeev K. Verma*, Ramarao Ghorpade, Ajay Pratap and M. P.
More informationDegradation of Aliphatic Polyesters in the Presence of Inorganic Fillers
Degradation of Aliphatic Polyesters in the Presence of Inorganic Fillers G. Chouzouri, M. Xanthos To cite this version: G. Chouzouri, M. Xanthos. Degradation of Aliphatic Polyesters in the Presence of
More informationSpecific N-Alkylation of Hydroxypyridines Achieved by a Catalyst- and Base-Free Reaction with Organohalides
Supporting Information Specific N-Alkylation of Hydroxypyridines Achieved by a Catalyst- and Base-Free Reaction with Organohalides Bin Feng, Yang Li, Huan Li, Xu Zhang, Huamei Xie, Hongen Cao, Lei Yu,
More informationSupporting Information for. Use of the Curtius Rearrangement of Acryloyl Azides in the Synthesis of. 3,5-Disubstituted Pyridines: Mechanistic Studies
Supporting Information for Use of the Curtius Rearrangement of Acryloyl Azides in the Synthesis of 3,5-Disubstituted Pyridines: Mechanistic Studies Ta-Hsien Chuang* a, Yu-Chi Chen b and Someshwar Pola
More informationSpirits cup Article no Dessert cup Article no Diamond bowl Article no Clear cup Article no. 2749, 10176
This specification describes articles of the material group PLA Poly-lactic acid Material description: PLA forms through the production of lactic acid from glucose from fermentation. Then a polymerization
More informationSupporting Information. as the nitro source
Supporting Information Efficient ipso-nitration of arylboronic acids with iron nitrate as the nitro source Min Jiang, a,b Haijun Yang,* a,b Yong Li, a,b Zhiying Jia b and Hua Fu b a Beijing Key Laboratory
More informationThe Effect of Molecular Weight of Polycaprolactone on the Ester Interchange Reactions during Melt Blending with Poly(ethylene terephthalate)
Polymer Journal, Vol. 34, No. 5, pp 313 319 (2002) The Effect of Molecular Weight of Polycaprolactone on the Ester Interchange Reactions during Melt Blending with Poly(ethylene terephthalate) Kyung Yul
More informationSupporting Information
Electronic upplementary Material (EI) for Polymer Chemistry. This journal is The Royal ociety of Chemistry 2017 upporting Information Photocrosslinked PVDF-based star polymer coatings: An all-in-one alternative
More informationSupplementary figures
Supplementary figures Supplementary Figure 1. Overlaid GPC traces (RI) of the PFDMS 61 aliquot, pure PFDMS 61-b- PMVS 574 copolymer and BCP P after sulfurisation of pendant phosphines. 1 Supplementary
More informationStudent Handout. This experiment allows you to explore the properties of chiral molecules. You have
Student Handout This experiment allows you to explore the properties of chiral molecules. You have learned that some compounds exist as enantiomers non-identical mirror images, such as your left and right
More informationPreparation of Stable Aziridinium Ions and Their Ring Openings
Supplementary Information Preparation of Stable Aziridinium Ions and Their Ring Openings Yongeun Kim a Hyun-Joon Ha*, a Sae Young Yun b and Won Koo Lee,*,b a Department of Chemistry and Protein Research
More informationElectron Beam Curable Varnishes Rapid Processing of Planarization Layers
Electron Beam Curable Varnishes Rapid Processing of Planarization Layers Juliane Fichtner, Michaela Hagenkamp, Markus Noss, Steffen Günther AIMCAL R2R Conference USA 2017 Naples, Florida, October 15-18,
More informationELECTRONIC SUPPLEMENTARY INFORMATION
ELECTRIC SUPPLEMETARY IFRMATI Searching for new cell-penetrating agents: hybrid cyclobutane-proline γ, γ peptides. Esther Gorrea, a Daniel Carbajo, b,c Raquel Gutiérrez-Abad, a na Illa, a Vicenç Branchadell,
More informationCarboxylic Acid Derivatives Reading Study Problems Key Concepts and Skills Lecture Topics: Structures and reactivity of carboxylic acid derivatives
Carboxylic Acid Derivatives Reading: Wade chapter 21, sections 21-1- 21-16 Study Problems: 21-45, 21-46, 21-48, 21-49, 21-50, 21-53, 21-56, 21-58, 21-63 Key Concepts and Skills: Interpret the spectra of
More informationImprovement in First Carbonation Sludge Settling by Selection of a Better Flocculent Addition point and. Flocculent. Jeffrey L. Carlson, Ph.
Improvement in First Carbonation Sludge Settling by Selection of a Better Flocculent Addition point and the Addition of Starch as a Second Flocculent. Jeffrey L. Carlson, Ph.D Upasiri i Samaraweera, Ph.D
More informationSupporting Information. Chemoenzymatic Synthesis of Galectin Binding. Glycopolymers
Supporting Information Chemoenzymatic Synthesis of Galectin Binding Glycopolymers Jessica H. Ennist, Henry R. Termuehlen, Samuel P. Bernhard, Mackenzie S. Fricke, and Mary J. Cloninger* Department of Chemistry
More informationDevelopment of a near-infrared fluorescent probe for monitoring hydrazine in serum and living cells
Supporting Information for Development of a near-infrared fluorescent probe for monitoring hydrazine in serum and living cells Sasa Zhu, Weiying Lin,* Lin Yuan State Key Laboratory of Chemo/Biosensing
More informationDirect ortho-c H Functionalization of Aromatic Alcohols Masked by Acetone Oxime Ether via exo-palladacycle
Direct ortho-c H Functionalization of Aromatic Alcohols Masked by Acetone Oxime Ether via exo-palladacycle Kun Guo, Xiaolan Chen, Mingyu Guan, and Yingsheng Zhao* Key Laboratory of Organic Synthesis of
More informationSupport Information. Table of contents. Experimental procedures. S2. Spectroscopic data... S2-S23. Photophysical properties..
Support Information Regioselective 2,6-dihalogenation of BODIPYs in 1,1,1,3,3,3-hexafluoro-2-propanol and preparation of novel meso-alkyl polymeric BODIPY dyes Liang Wang a, Jian-Wei Wang a, Ai-jun Cui
More information