Material Safety Data Sheet Arsenious Acid Solution. Section 1 - Chemical Product and Company Identification

Transcription

1 An ISO9001 Certified Company Section 1 - Chemical Product and Company Identification MSDS Name: Catalog Numbers: LC11520 Synonyms: None Company Identification: LabChem Inc 200 William Pitt Way Pittsburgh, PA Company Phone Number: (412) Emergency Phone Number: (800) CHEMTREC Phone Number: (800) or Section 2 Composition, Information on Ingredients CAS# Chemical Name: Percent Water > Arsenic trioxide Sulfuric acid 0.04 Section 3 - Hazards Identification Emergency Overview Appearance: Clear, colorless solution Warning! Poison. Harmful if inhaled. May be fatal if swallowed. This substance has caused adverse reproductive and fetal effects in animals. May cause central nervous system effects, cardiac disturbances, lung damage, blood abnormalities, and liver and kidney damage. Causes eye and skin irritation. May cause severe respiratory and digestive tract irritation with possible burns. Cancer hazard. Target Organs: Kidneys, central nervous system, liver, lungs, cardiovascular system, red blood cells, skin. Potential Health Effects Eye: Contact produces irritation, tearing, and burning pain. May cause conjunctivitis. Skin: Causes irritation with burning pain, itching, and redness. May cause dermatitis

2 Ingestion: May be fatal if swallowed. Causes severe digestive tract burns with abdominal pain, vomiting, and possible death. May cause hemorrhaging of the digestive tract. Ingestion of arsenical compounds may cause burning of the lips, throat constriction, swallowing difficulties, severe abdominal pain, severe nausea, projectile vomiting, and profuse diarrhea. Ingestion of arsenic compounds can produce convulsions, coma, and possibly death within 24 hours. Inhalation: May cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema. Inhalation of arsenic compounds may lead to irritation of the respiratory tract and to possible nasal perforation. Long-term exposure to arsenic compounds may produce impairment of peripheral circulation. Chronic: May cause liver and kidney damage. Chronic inhalation may cause nasal septum ulceration and perforation. May cause anemia and other blood cell abnormalities. Chronic skin effects include: cracking, thickening, pigmentation, and drying of the skin. Arsenic trioxide can cause cancer in humans. Other long term effects include: anemia, liver and kidney damage. Section 4 - First Aid Measures Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower lids until no evidence of chemical remains. Get medical aid at once. Skin: Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid. Ingestion: Get medical aid at once. Give conscious victim large quantities of water to dilute acid. Do not use gastric lavage or induce vomiting. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation. Notes to Physician: Treat symptomatically and supportively. Section 5 - Fire Fighting Measures General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Highly toxic vapors may be emitted during a fire. Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Autoignition Temperature:. Flash Point:. NFPA Rating: CAS# : Health- 0, Flammability- 0, Instability- 0. CAS# : Health- 3, Flammability- 0, Instability

3 CAS# : Health- 3, Flammability- 0, Instability- 1. Explosion Limits: Lower: n/a Upper: n/a Section 6 - Accidental Release Measures General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spills with absorbent (vermiculite, sand, fuller's earth) and place in suitable containers labeled for later disposal. Section 7 - Handling and Storage Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Do not allow contact with water. Use only with adequate ventilation or respiratory protection. Storage: Store capped at room temperature. Protect from heat and incompatibles. Do not store in metal containers. Section 8 - Exposure Controls, Personal Protection Engineering Controls: Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. See 29CFR for regulatory requirements pertaining to all occupational exposures to inorganic arsenic. Exposure Limits: Chemical Name: ACGIH NIOSH OSHA Water None of the components None of the components None of the components Arsenic trioxide are on this list 0.01 mg/m3 TWA (as As) (listed under Arsenic, inorganic compounds) are on this list 5 mg/m3 IDLH (as As) (listed under Arsenic, inorganic compounds) are on this list 10 µg/m3 TWA (as As) (listed under Arsenic, inorganic compounds) Sulfuric acid 1 mg/m3 TWA 1 mg/m3 TWA 3 mg/m3 STEL OSHA Vacated PELs: Sulfuric acid: 1 mg/m3 TWA Personal Protective Equipment Eyes: Do not wear contact lenses when working with chemicals. An eye wash fountain should be available in the immediate work area. Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure

4 Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - Physical and Chemical Properties Physical State: Liquid Color: Colorless Odor: Odorless ph: Acidic Vapor Pressure:. Vapor Density:. Evaporation Rate:. Viscosity:. Boiling Point:. Freezing/Melting Point:. Decomposition Temperature:. Solubility in water:. Specific Gravity/Density: 1.0 Molecular Formula:. Molecular Weight:. Section 10 - Stability and Reactivity Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Oxidizing materials, metals. Hazardous Decomposition Products: Arsenic oxides, arsine. Hazardous Polymerization: Has not been reported. Section 11 - Toxicological Information RTECS: CAS# : ZC CAS# : CG CAS# : WS LD50/LC50: CAS# : Oral, rat: LD50 = >90 ml/kg

5 CAS# : Oral, mouse: LD50 = 20 mg/kg Oral, rabbit: LD50 = µg/kg Oral, rat: LD50 = 10 µg/kg. CAS# : Inhalation, mouse: LC50 =320 mg/m3/2h Inhalation, rat: LC50 =510 mg/m3/2h Oral, rat: LD50 = 2140 mg/kg. Carcinogenicity: CAS# : Not listed as a carcinogen by ACGIH, IARC, NIOSH, NTP, OSHA, or CA Prop 65. CAS# : Listed as a carcinogen by IARC, NTP, and CA Prop 65. CAS# : Listed as a carcinogen by ACGIH, OSHA, and IARC. Epidemiology: Eye, skin, mucous membrane irritant. May cause sensitization. Poisoning may affect gastrointestinal, cardiovascular, and central nervous systems, liver, and kidneys. Teratogenicity: Reproductive: Mutagenicity: Neurotoxicity: Section 12 - Ecological Information Section 13 - Disposal Considerations Dispose of in accordance with Federal, State, and local regulations. US DOT Shipping Name: Not regulated Hazard Class: UN Number: Packing Group: Section 14 - Transport Information Section 15 - Regulatory Information US Federal TSCA: CAS# is listed on the TSCA Inventory

6 CAS# is listed on the TSCA Inventory. CAS# is listed on the TSCA Inventory. SARA Reportable Quantities (RQ): CAS# : final RQ = 1 pound (0.454 kg) CAS# : final RQ = 1000 pounds (454 kg) CERCLA/SARA Section 313: Sulfuric acid is not at a high enough concentration to be reportable under Section 313. OSHA - Highly Hazardous: None of the components are on this list. US State State Right to Know: Arsenic trioxide can be found on the following state Right-to-Know lists: California, New Jersey, Florida, Pennsylvania, Massachusetts. Sulfuric acid can be found on the following state Right-to-Know lists: California, New Jersey, Florida, Pennsylvania, Minnesota, Massachusetts. California Regulations: WARNING: This product contains a chemical known to the state of California to cause cancer. European/International Regulations Canadian DSL/NDSL: CAS# is listed on Canada's DSL List. CAS# is listed on Canada's DSL List. CAS# is listed on Canada's DSL List. Canada Ingredient Disclosure List: CAS# is not listed on Canada's Ingredient Disclosure List. CAS# is listed on Canada's Ingredient Disclosure List. CAS# is listed on Canada's Ingredient Disclosure List. Section 16 - Other Information MSDS Creation Date: September 9, 1998 Revision Date: March 4, 2010 Information in this MSDS is from available published sources and is believed to be accurate. No warranty, express or implied, is made and LabChem Inc. assumes no liability resulting from the use of this MSDS. The user must determine suitability of this information for his application