Lifestyle Medicine Summit 生活型態醫療高峰會

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1 Lifestyle Medicine Summit 生活型態醫療高峰會 (Sat.) 8:30 am 5:00 pm (Sun.) 8:30 am 5:00 pm 香格里拉台北遠東國際大飯店,3F 遠東宴會廳 ( 台北市敦化南路二段 201 號 ) 主辦單位 : 中華民國職業病醫學會 協辦單位 : 中華生醫科技股份有限公司 Metagenics Inc. 美國在台協會商務組 現今的醫療照護領域已經產生了不同的轉變 隨著病患權益的日受重視, 醫療人員也在思考針對疾病潛藏根源的解決對策 在這一場 2014 年的生活型 態醫療高峰會當中, 我們邀請最傑出的學者和專業醫師, 包括營養治療專家 Dr. John P. Troup 家醫科醫師 Dr. Bridget Briggs 與外科及腸胃科醫師 Dr. Robert Martindale, 共同研探如何運用在醫療照護上的最新思維與突破性的觀點, 結 合更好的營養調節與生活型態醫療, 以及個人化的診斷, 幫助改善病患的狀況 內容將包括 : 探討代謝症候群相關的臨床指標及症狀處理 討論最新的臨床學術研究文獻, 探討個人化的生活型態醫療調整, 讓病患獲得改善 探討腸道益生菌相與益生質對於腸胃及整體健康的影響 分析造成血脂異常相關的血管病變及代謝症候群的潛藏原因 探討營養調節與基因表現的互動關聯, 以及對病患照護的調整 研討治療性的生活型態調整對於病患狀況的效益

2 There is a paradigm shift occurring in healthcare today. Patients are becoming empowered and practitioners are looking for solutions to address the underlying cause of disease. The 2014 Lifestyle Medicine Summit will feature leading researcher Dr. John P. Troup and healthcare professionals Dr. Bridget Briggs & Dr. Robert Martindale that are transforming medicine with cutting-edge insights and innovations in applied patient care. The 2014 Summit will demonstrate how patient care can be improved with personalized diagnostics combined with smarter nutritional approaches and contemporary lifestyle medicine that truly makes a difference in outcomes, including: Identify diagnostic indicators used to manage metabolic syndrome parameters Discuss the recent published clinical studies that support the positive outcomes in the application of personalized lifestyle medicine Identify the current science behind the role of probiotics/prebiotics in overall gut health and systemic health Review the underlying causes of dyslipidemia-induced vascular disease and metabolic syndrome Discuss the interplay of genetics and nutrition for improved insights into patient care Discuss how implementing a therapeutic lifestyle change (TLC) program can improve patients outcome

3 AGENDA (Sat) TIME 08:30 09:00 REGISTRATION 09:00 10:20 10:20 10:40 TEA BREAK 10:40 12:00 12:00 13:30 LUNCH 13:30 14:50 14:50 15:10 TEA BREAK SCHEDULE New Clinical Nutrition Insights and Solutions for the Management of Chronic Conditions. 1. Digestive Health 2. Cognitive Performance SPEAKER: Dr. John P. Troup Probiotics, Microbiome and Gastrointestinal Health From the Germ Theory to Germ Therapy SPEAKER: Dr. Robert G. Martindale 21 st Century Advances in Detoxification for the Management of Chronic Illness SPEAKER: Dr. Bridget R. Briggs 15:10 16:20 Clinical Applications to the Topics Above. SPEAKER: Dr. Robert G. Martindale & Dr. Bridget R. Briggs 16:20 17:00 Discussion

4 TIME 08:30 09:00 REGISTRATION 09:00 10:20 10:20 10:40 TEA BREAK 10:40 12:00 12:00 13:30 LUNCH 13:30 14:50 14:50 15:10 TEA BREAK (Sun) SCHEDULE The Use of Clinical Nutrition in the Management of Diabetes and Cardiovascular Health. SPEAKER: Dr. John P. Troup Improving Cardiovascular Health and Diabetes with Lifestyle Medicine: Reversing the Diabesity Pandemic SPEAKER: Dr. Bridget R. Briggs Improving Cardiovascular Health and Diabetes with Lifestyle Medicine: GI Restoration SPEAKER: Dr. Bridget R. Briggs 15:10 16:20 Clinical Applications to the Topics Above. SPEAKER: Dr. Bridget R. Briggs 16:20 17:00 Discussion

5 講師介紹 John P. Troup, Ph.D. Dr. Troup 目前於 Metagenics, Inc. 公司擔任科學總監一職 他於 Marquette University 完成人類新陳代謝領域的博士學位, 專長於營養科學與新陳代謝 先前曾任職於輝瑞 Pfizer 雀巢 Nestle 達能 Danone 諾華 Norvatis 等知名 國際營養或藥物公司, 負責帶領研究開發計畫工作 在 1996 年至 2000 年期 間,Dr. Troup 曾擔任美國國家營養食品協會委員, 負責日常營養補充品部分 的品保 (quality assurance) 及法規方面事務 從這些經歷當中累積豐富的經驗 與能力, 得以開發臨床營養與醫療照護療程, 提供醫師應用, 改善病患健 康 Dr. Troup currently serves as Chief Science Officer of Metagenics, Inc. Dr. Troup earned his PhD in human metabolism at Marquette University, his majors are Nutrition Sciences & Metabolism. Previously he led global R&D programs in nutrition healthcare companies including Pfizer, Nestle, Danone and Novartis. He had been the Board Member of the National Nutritional Foods Association, an industry association for the dietary supplement category, Co-chair for the Quality Assurance (ComPli) Committee and Legislative Committee, 1996 to In these roles he has provided leadership in the delivery of clinical nutrition and medical development programs supporting health outcomes for practitioners and patients

6 Bridget Briggs, MD Dr. Briggs 是專精於整合醫療的家庭醫學科醫師 她畢業於 UC San Diego, 在 南內華達大學醫學中心 (University Medical Center of Southern Nevada) 完成婦 產科專科訓練後即任職於河岸郡醫學中心 (Riverside County Regional Medical Center) 家庭醫學科醫師 自 2001 年通過 Scripps Institute of Integrative Medicine 的認證後,Dr. Briggs 就成為私人執業的整合醫療醫師 她經常與功 能醫學領域的領袖人物如 Dr. Jeffrey S. Bland 和 Dr. Mark Hymer 共同舉辦講 座, 專長於生活型態醫學療程對於慢性疾病預防與治療的臨床應用, 包括心 臟血管與代謝疾病相關的健康問題 Dr. Briggs is a board certified family practitioner who specializes in integrative medicine. She completed her medical degree at the University of California at San Diego; an internship in obstetrics and gynecology at University Medical Center of Southern Nevada (UMC) in Las Vegas; and a residency in family practice at Riverside County Regional Medical Center. She received certification through Scripps Institute for Integrative Medicine and has been in private practice since Dr. Briggs frequently lectures with other industry thought leaders (including Dr. Jeffrey S. Bland and Dr. Mark Hyman) on the clinical application of lifestyle medicine programs to manage common chronic diseases such as cardiometabolic issues.

7 Robert Martindale, MD, PhD Dr. Martindale 為外科醫學教授, 任職於美國 Oregon Health & Science University 的腸胃科及一般外科主任, 兼任臨床營養醫療總監 他在 George Washington University 完成臨床醫師教育, 並且在 UCLA 取得營養新陳代謝的 博士學位 Dr. Martindale 致力於外科醫學與營養學的教育, 並特別注重在外 科術後加護病房照護的營養新陳代謝狀況 目前 Dr. Martindale 已是多個美國 及國際外科醫學及營養科學期刊的編審委員, 本身亦有超過 200 篇以上的著 作發表, 包括學術研究 文獻回顧以及教學書籍篇章, 同時亦編撰有知名的 加護病房營養照護教科書 Nutritional Considerations in the Intensive Care Unit: Science, Rationale, and Practice Dr. Martindale is Professor of Surgery, Chief of the Division of Gastrointestinal and General Surgery, as well as Medical Director for Hospital Nutrition at Oregon Health & Science University. He received his MD from George Washington University in Washington, DC and his PhD in Nutrition Metabolism at UCLA. Dr. Martindale s primary focus throughout his professional career has been on surgical and nutritional education. His primary academic focus is in the area of surgical and critical care nutrition and metabolism. He is a member of numerous professional organizations at the local, national, and international level and is on the editorial board for several surgical and nutritional journals. He is the author of over 200 publications, including peer-reviewed original manuscripts, review articles, chapters, as well as being the co-editor of a major textbook on nutrition for the ICU population: Nutritional Considerations in the Intensive Care Unit: Science, Rationale, and Practice.

8 Abstracts (Sat) 09:00 10:20 New Clinical Nutrition Insights and Solutions for the Management of Chronic Conditions. 1. Digestive Health 2. Cognitive Performance Speaker: Dr. John P. Troup Quality nutrition has clearly been shown to influence health status and health outcome. This association and influence plays a role in both preventive and active management of conditions such that progression of chronic illness can be managed and minimized. This effect has been documented across all chronic illness states and two under-appreciated area of health impact are seen in digestive health and in cognitive performance. Digestive Health. With the recent work done in the human microbiome project, mounting evidence describes the important role of probiotics and prebiotics and the synergestic effect the combination provides. As new science is available, more specific information on the functional effect and importance of probiotics has shown that specific and targeted effects on gut and immune activity is more important than the activity level of probiotics alone. This precise effect of probiotics has led to the development of new targeted uses resulting in improved outcomes and led to the development of Precision Biotics. These biotics provide both a protective effect of the gut barrier, influence gut transport mechanisms and stimulate the immune response - making these new probiotics an important part of the clinical regimen. This presentation will describe the specific new probiotics, their functional role and clinical outcome benefits and present specific probiotic solutions and options available for use in managing patients. Cognitive Health. Cognitive performance can be maintained with optimal nutrition and several key nutrients have been shown to support cognitive development and performance. Additionally a number of natural products have been shown to support neuronal function, energetics and activation for overall benefit. These include cognitive performance, mood, anxiety, and relaxation. These nutritional options and solutions will be reviewed during the presentation

9 (Sat) 10:40 12:00 Probiotics, Microbiome and Gastrointestinal Health From the Germ Theory to Germ Therapy Speaker: Dr. Robert G. Martindale Regulatory bodies use the definition for probiotics as; living microorganisms which, when ingested in adequate amounts, provide health benefits to the host. The commensal relationship which we have with the bacteria that live on and within us has been known for decades. However, recent evidence has established that this host-microbe relationship is much more complex and intertwined that ever conceived. The beneficial mechanisms are numerous and include improved gastrointestinal barrier function, maintaining optimal ph and redox potential at the mucosal barrier, modification of the gut flora by inducing host cell antimicrobial peptides, release of antimicrobial factors, competing for epithelial adherence at binding sites on the mucosa, and immunomodulation to the advantage of the host. Pre- and Probiotics, when considered in clinical practice, have traditionally been used for prophylaxis; however, there is growing data suggesting treatment benefits in numerous common disease states. This lecture will primarily focus on probiotics as treatment for and prevention of several acute and chronic gastrointestinal disorders such as Helicobacter pylori, Clostridium difficile, ability to clear vancomycin-resistant enterococci necrotizing, enterocolitis in pediatrics, irritable bowel syndrome, inflammatory bowel disease, and nonalcoholic fatty liver disease NASH). The lecture will also touch on the influence of probiotics and gut flora and its role in the epidemic of obesity. GI cancers will be addressed keeping in mind the limitations of the current literature. It is inaccurate to generalize findings observed in a single probiotic species to all probiotics. This reasoning is due to the variability of colonizing abilities of native intestinal floras, heterogeneity of the probiotic strains, doses, timing and duration of treatments. Given these limitations, multiple animal and human studies have shown anti-inflammatory and selective antimicrobial effects of specific probiotics. Some studies suggest a role for probiotics as supplemental treatment, in combination with antibiotics, for the aforementioned disease processes. It is apparent from this review that the efficacy of probiotics in common gastrointestinal disorders is widely variable and multifaceted. More focused clinical and basic science research is necessary to better understand the treatment potential of various probiotics.

10 (Sat) 13:30 14:50 21 st Century Advances in Detoxification for the Management of Chronic Illness Speaker: Dr. Bridget R. Briggs Pioneering research on pollutants and their influence on cellular function coupled with investigations on environmental epigenetics has changed not only how we think about the connection of pollutants to chronic disease, but also what we do about it. At this seminar you will learn leading-edge information on clinically relevant biomarkers of toxicity and groundbreaking approaches to chronic illness management. You will discover: Important biomarkers of impaired detoxification Clinical applications of detoxification in the management of chronic illness The role of glutathione in detoxification Lifestyle medicine therapies to support detoxification processes Dr. Briggs will take you on an exploration of the latest understanding of the function of glutathione precursors and glutathione recycling in improving detoxification processes and liver function. To complement this scientific presentation, Dr. Briggs will discuss the relationship of toxicity to common chronic conditions including digestive disorders, obesity, and cognitive decline and present nutritional and lifestyle medicine protocols for clinical implementation. Key clinical takeaways: Understand the relationship between toxins and chronic diseases Master how to assess the impact of pollutants on individual patients Learn why even a very small concentration of a substance can have a larger-thananticipated effect on physiology Discover which chronic diseases are most connected to toxin exposures Master nutritional protocols for metabolic detoxification for patients with excess toxic burden

11 (Sat) 15:10 16:20 Clinical Applications to the Topics Above. Speaker: Dr. Robert G. Martindale & Dr. Bridget R. Briggs There is a paradigm shift occurring in healthcare today. Patients are becoming empowered and practitioners are looking for solutions to address the underlying cause of disease. Dr. Robert G. Martindale and Dr. Bridget R. Briggs are transforming medicine with cutting-edge insights and innovations in applied patient care. The 2014 Summit will demonstrate how patient care can be improved with personalized diagnostics combined with smarter nutritional approaches and contemporary lifestyle medicine that truly makes a difference in outcomes. In this session, we discuss clinical applications, published basic and clinical science studies along with the results of intervention trials to effectively implement personalized lifestyle medicine to specific chronic disease conditions.

12 (Sun) 09:00 10:20 The Use of Clinical Nutrition in the Management of Diabetes and Cardiovascular Health. Speaker: Dr. John P. Troup Recent epidemiological evidence has shown that consumption of a poor diet high in low quality carbohydrates and low in protein increases the risk of developing obesity and or diabetes. With poor diets, the loss of control of normal insulin and glucose control increases the genetic predisposition of these disease states to increase 10 fold and the result of metabolic energetics overload leading to mitochondrial overload. With over 60% of selected patient groups at risk and actively needing to manage glucose to avoid disease progression specific clinical nutrition solutions are needed to effectively manage insulin response for control of glucose. To this end, optimal macronutrient balance has been developed and shown to result in maintenance of normal insulin response thus avoiding development of insulin resistance and thus the healthy function of beta cells and ideal control of the glucose response. When combined with a high quality source of carbohydrates and protein improved metabolic control was observed with improved HbA1c. Additional benefits for cardiovascular health outcomes have also been described as a result of using medical nutrition solutions to manage this health issue and also to facilitate transition to complete dietary improvement. The results of these studies will be discussed and specific clinical solutions presented during this presentation.

13 (Sun) 10:40 12:00 Improving Cardiovascular Health and Diabetes with Lifestyle Medicine: Reversing the Diabesity Pandemic Speaker: Dr. Bridget R. Briggs Obesity and blood sugar issues now affect over 1 billion people worldwide, many undiagnosed. And metabolic syndrome is emerging as a major driver of most chronic diseases of aging, such as cardiovascular disease. But many current intervention strategies have proven ineffective or harmful. Dr. Briggs will explore innovative clinical approaches to the diabesity continuum of health problems ranging from mild insulin resistance and overweight to obesity and diabetes that affect over 1 billion people worldwide. These highly prevalent conditions also contribute to cardiovascular disease and other chronic illnesses that compromise healthy aging. At this practice changing, Dr. Briggs will explain potential underlying causes that provide avenues for customized therapeutic intervention, such as environmental toxins, food sensitivities, hormonal dysregulation, gut microbiology, nutrient deficiencies, and abnormal gene expression. To complement this presentation, Dr. Bridget Briggs will discuss the growing trend of testing for genetic polymorphisms and how to design individual treatment programs to help prevent cardiometabolic conditions. Key clinical takeaways: Understand the concept of food as information in nutritional modulation of health and disease Learn how phytonutrients influence healthy aging through their impact on genomic stability and metabolic flexibility Master how to assess symptoms to diagnose and identify risk for diabetes and cardiovascular-related diseases Learn how to address unique causes of cardiometabolic issues with personalized lifestyle intervention strategies Understand how to apply simple nutrigenomic protocols for lifetime wellness

14 (Sun) 13:30 14:50 Improving Cardiovascular Health and Diabetes with Lifestyle Medicine: GI Restoration Speaker: Dr. Bridget R. Briggs Gastrointestinal complaints are among the leading reasons that patients seek health care. Common approaches may alleviate symptoms such as occasional indigestion, occasional heartburn, abdominal cramping, urgent bowel movements, or occasional constipation. They may only temporarily mask the underlying issues and have potential adverse effects. At this seminar you will discover the latest research and learn how to incorporate nutrition and lifestyle medicine approaches that are practical, natural, and safe ways to improve patient health. You will also gain valuable insights into the digestive system and new clinically effective protocols for your practice. Learn about leaky gut syndrome and the association with autoimmune disease Discover clinically effective approaches to addressing dysbiosis and healing the intestinal lining Relieve common complaints for occasional indigestion, occasional heartburn, abdominal cramping, urgent bowel movements, or occasional constipation without the potential adverse effects.

15 (Sun) 15:10 16:20 Clinical Applications to the Topics Above. Speaker: Dr. Bridget R. Briggs There is a paradigm shift occurring in healthcare today. Patients are becoming empowered and practitioners are looking for solutions to address the underlying cause of disease. Dr. Bridget Briggs is transforming medicine with cutting-edge insights and innovations in applied patient care. The 2014 Summit will demonstrate how patient care can be improved with personalized diagnostics combined with smarter nutritional approaches and contemporary lifestyle medicine that truly makes a difference in outcomes. In this session, we discuss clinical applications, published basic and clinical science studies along with the results of intervention trials to effectively implement personalized lifestyle medicine to specific chronic disease conditions.

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