Social Marketing Plus for Diarrheal Disease Control: Point-of-Use Water Disinfection and Zinc Treatment (POUZN) Project
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1 Social Marketing Plus for Diarrheal Disease Control: Point-of-Use Water Disinfection and Zinc Treatment (POUZN) Project The Social Marketing Plus for Diarrheal Disease Control: Point-of-Use Water Disinfection and Zinc Treatment (POUZN) Project is a $12 million project funded by the United States Agency for International Development (USAID). The goal of the POUZN program was to expand the use of point-of-use (POU) water disinfection and zinc products for the prevention and treatment of diarrhea through private sector channels. The POUZN project was implemented between 25 and 21 by Abt Associates and Population Services International (PSI). PSI implemented POUZN projects in the following countries: Angola, Benin, Democratic Republic of the Congo (DRC), Haiti, Kenya, Madagascar, Malawi, Nepal, and Rwanda. The POUZN project sought to prevent and treat diarrhea using both commercial and social marketing approaches. This was achieved by introducing and scaling up provision of household water treatment and zinc combined with oral rehydration salts. In each country PSI executed an accompanying behavior change strategy to increase knowledge about diarrheal disease prevention and treatment; instill confidence about the benefits of POU water and zinc treatment products, and overcome ability and motivational barriers to correct and consistent use. DIARRHEA PREVENTION Household water treatment and safe storage (HWTS) makes an immediate difference on the lives of those who rely on transporting and storing water in their homes by ensuring each sip of water is safe to drink. These simple, safe, and inexpensive techniques have been proven effective at treat drinking water and storing it in the home with typical reductions of diarrhea by 3-5 percent. HWTS works to address water quality issues while complementing water supply, hygiene, and sanitation interventions. HWTS can be adopted rapidly, at national scale, in both development and emergency situations. The target populations were children under five years of age and their caregivers, particularly in households that store water gathered from remote collection points, have intermittent water service, or suffer from poor water quality. In Rwanda, the program also targeted people with HIV/AIDS, whose compromised immune systems make them particularly vulnerable to the effects of unsafe water and diarrheal illness. Under the POUZN project, PSI promoted a range of household water treatment products including: Safe water system, a chlorine-based water treatment product consisting of a sodium hypochlorite solution in a standard 15 ml bottle with a cap that enables appropriate dosing for the traditionally used 2 liter container ; PUR, a flocculent- disinfectant manufactured by Procter & Gamble is particularly useful for turbid water sources; and Aquatabs, manufactured by Medentech in Ireland, which contains the active ingredient sodium dichloroisocyanurate (NaDCC) which rapidly dissolves in water to kill microorganisms that cause diarrhea. Table 1: Water disinfection products promoted by PSI under the POUZN project POU Product Form # Liters Treated Manufacturer Countries Safe Water System Liquid 1 Locally manufactured except Haiti Angola, Haiti, Kenya, Malawi, Rwanda PUR Powder 1 Proctor & Gamble DR Congo, Kenya & Malawi Aquatabs Tablet 2 Medentech Benin & Kenya 1
2 The project s communication objectives for consumers of POU products were to ensure that caregivers understand the connection between unsafe water and diarrhea; establish awareness of POU products as a year-round, easy-to-use, high quality, effective, easily accessible and affordable method to prevent childhood diarrhea; establish awareness of the importance of adopting safe hygiene practices (including hand-washing at critical times and storing treated water correctly in the home); and encourage trial, correct and sustained use of POU products. However, in some places PSI found that the most effective messages were not focused on health outcomes. Rather these messages leveraged caregivers concerns with social status or desire to be good parents. For example in Rwanda, their safe water campaign was call the Good Life campaign, and sought to position Sûr Eau as a water treatment product that offers a caregiver comfort and peace of mind from knowing that she is doing the right thing to ensure the well-being of her children DIARRHEA TREATMENT The zinc treatment component of POUZN stemmed from the substantial body of evidence demonstrating that zinc, when given in conjunction with ORS for at least 1 days during and after diarrhea, reduces the duration and severity of diarrheal episodes and can have a protective effect against diarrhea morbidity in the subsequent two month period after treatment. 1 In May 24 the World Health Organization (WHO) and the United Nations Children s Fund (UNICEF) issued a new recommendation for diarrhea management which endorsed the use of zinc supplements, along with low-osmolarity 2 ORS, as a new safe and effective low cost treatment for diarrhea to reduce death and illness in children in the developing world. 3 USAID embraced these recommendations and engaged cooperating organizations to both assist Ministries of Health and their public sector clinics to introduce zinc within standard diarrhea management protocols as well as to introduce zinc treatment through private sector channels. Table 2. Zinc products promoted by PSI under the POUZN project Product Form Manufacturers Country Diarrhea Treatment Kit Diarrhea Treatment Kit: Ten 2mg tablets of zinc sulfate and two sachets of flavored ORS Imported zinc (Nutriset) and ORS Benin and Madagascar Zinc alone ORS sold separately Dispersible 1 or 2 mg zinc sulfate tablets in 1 tablet dose Local manufacturers : CTL, DJPL, NPL Nepal Communication objectives for the zinc portion of the program were similar. These focused on ensuring that caregivers of children under five understand that zinc together with ORS is the appropriate treatment for uncomplicated diarrhea, know that dispersible zinc tablets are available from either public or private sector clinics/pharmacies, understand that unnecessary diarrhea treatments (anti-diarrheals and antibiotics) may be harmful to their children and not the most effective treatment, and correctly treat their child by providing both zinc and ORS for the recommended periods of time. Given that the zinc and ORS were to be purchased separately in some countries, the POUZN team emphasized the importance of utilizing ORT/ORS together with zinc. 1 Abdullah H Baqui, Robert E Black, Shams El Arifeen, Mohammad Yunus, Joysnamoy Chakraborty, Saifuddin Ahmed, J Patrick Vaughan (22). Effect of zinc supplementation started during diarrhea on morbidity and mortality in Bangladeshi children: community randomized trial. British Medical Journal; 325:159 (9 November). Zinc Investigators Collaborative Group (2). Therapeutic effects of oral zinc in acute and persistent diarrhea in children in developing countries: pooled analysis of random controlled trials. Am J Clin Nutr 72: The new low osmolarity ORS has lower levels of both glucose and sodium which has been found to reduce stool output, vomiting, and unscheduled IV therapy. 3WHO/UNICEF. 24. Clinical Management of Acute Diarrhoea, Joint Statement. 2
3 PROJECT RESULTS Through the POUZN project, PSI conducted program evaluations in seven of its countries based on household surveys, qualitative surveys and mystery client surveys. Diarrhea Prevention: With POUZN support, PSI conducted program evaluation in four of the POU programs. In the majority of the POUZN water disinfection programs, both trial (ever) use of the products and current use of the water treatment products increased significantly. Exposure to mass media, social/community support, perceived availability of POU water treatment, perceived threat from unsafe water, and individual self-confidence in one s ability to appropriately treat water were all significant factors in increased use. For example, through its effective partnerships with the public and private sectors, POUZN put POU into local shops and caregivers hands around the country, achieving near universal coverage in urban areas (99.5%) and reaching about just less than half that in rural areas. With such high coverage, usage rates increased dramatically. A 21 survey showed the proportion of those who had ever used POU doubling since 27, from 2 to 4. Moreover, 19% of survey respondents in 21 reported using POU in the last 24 hours to treat their water-- this translates to half a million Rwanda caregivers treating their families water every day. However the gap between trial and current use remains high. Future programs will need to consider this gap and develop strategies for increasing sustained use of POU products. Figure 1: Ever Use of Promoted POU Products 45% 4 35% 3 25% 2 15% 5% Benin DRC Kenya Rwanda Baseline Endline Figure 2: Current Use (Self-Reported) of Promoted POU Products 3 25% 2 15% 5% Benin DRC Kenya Rwanda Baseline Endline 3
4 Figure 3: Ever Use Versus Current Use of Promoted Products Ever Use Current Use 6 Benin DRC Kenya Rwanda Diarrhea Treatment: The POUZN project initiated zinc programs through private sector channels in Benin, Madagascar and Nepal. PSI was able to significantly increase utilization of zinc in a short time frame (under two years) in two of the programs, Benin and Nepal. In Madagascar the political crisis significantly hampered program implementation for an entire year. Overall the evaluations of zinc programs found that a large percentage of caregivers do not seek advice or treatment for diarrhea outside of the home as shown in Figure 4 below. This poses a challenge for particularly private sector programs. About 2 of respondents in Benin & Madagascar reported not treating diarrhea at all. In all three countries, 6-8 said they use home fluids or increased fluids. To gain the full benefits of the product, it is important to use zinc for the full 1-days. Compliance with the 1 day regime was mixed and will require attention in future programs. Figure 4. Diarrhea treatment practices 1 Percentage (%) Nepal Benin Madagascar No advice/treatment outside home No treatment Home fluids/increased fluids Source: POUZN-funded household surveys executed by PSI. As shown in Figure 6 below, in all three programs use of ORS along with the zinc was high, even when the products were not co-packaged. However, ORS/ zinc use rates may depend on the country s historical use of ORS. In Benin, Madagascar and Nepal, public sector pilots prior to POUZN provided baseline use rates of less than two percent. POUZN succeeded in increasing use rates to 31% in Benin and 15% in Nepal. Civil conflict in Madagascar hampered the POUZN private sector efforts but public sector districts, where zinc and ORS supplies were available, had achieved about 12% use. 4
5 Figure 5. Zinc Utilization in POUZN Program Countries Comparison with Baseline % of children with diarrhea in past 2 weeks treated with zinc Benin Nepal 15? Madagascar Baseline 4 Survey Figure 6. Correct Zinc Utilization in POUZN Program Countries 1 Percentage (%) of respondents Used zinc with ORS/ORT Used zinc for at least 1 days Used zinc for 1 days plus ORS/ORT Nepal Benin Madagascar OVERARCHING LESSONS LEARNED Significant increase of uptake of diarrhea prevention and treatment is achievable: By increasing access to important health products and exposure to messages focused on behavioral determinates, it is possible to increase uptake of diarrhea prevention and treatment. Uptake can be achieved with relatively limited resources and in shorter time frame: When the right conditions exist, scale up in the private sector can be achieved in a relatively short time. A coordinated public/private sector program which leverages alternative distribution channels is more effective than a program focusing on the private sector alone. To scale up diarrhea prevention and treatment, it is important to build on traditional social marketing and leverage alternative distribution channels such as public health clinics, community health workers, schools, and emergency relief to effectively reach mothers and children under five. Communications, which focus on the key determinants, are more likely to motivate desired behaviors. Both mass media and interpersonal channels of communication are essential to creating awareness and encouraging correct and consistent use. 5
6 Evaluation research is critical to monitor program success and to draw lessons to guide future program design. Diarrhea Prevention POU is affordable: Chlorine HWT products can be offered at a non-subsidized price that is affordable to most caregivers. Behavioral Determinants of POU were similar across countries: The significant predictors of household water treatment behavior were identified as: social support / social norms, self-efficacy (caregivers confidence in ability to practice the behavior), perceived availability of household water treatment and perceived threat from unsafe water. Integration of POU into on-going health programming helps to grow support for and sustain it as an intervention. For example, through its effective partnerships with the public and private sectors, POUZN put POU into local shops, health clinics, and community health workers and eventually caregivers hand across Rwanda, achieving near universal coverage in urban areas (99.5%) and reaching about just less than half that in rural areas. A 21 survey showed the proportion of those who had ever used POU doubling since 27, from 2 to 4. Moreover, 19% of survey respondents in 21 treated their water in the last 24 as verified by chorine residual. Diarrhea Treatment ORS and Zinc can be marketed effectively together: Given the high cost of packaging, ORS and zinc should be co-marketed but not necessarily co-packaged unless there is no ORS available on the market or very low use of ORS. Compliance remains a concern: Compliance with the 1 day regimen has been more challenging than anticipated. Care providers are very important influencers associated with diarrhea treatment: Training and detailing are not enough to motivate providers to recommend ORS and zinc instead of antibiotics or anti-diarrheals. One of the major challenges is convincing caregivers that zinc with ORS is more effective and safer than antibiotics and antidiarrheals. Incentives structures are set up to encourage a care provider to several more expensive treatments versus one inexpensive treatment. More studies need to be done to understand the care providers behavior and incentives. Training and detailing are not enough to motivate providers to recommend ORS and zinc instead of antibiotics or anti-diarrheals. One of the major challenges is convincing caregivers that zinc with ORS is more effective and safer than antibiotics and anti-diarrheals. 6
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