Medication Guide MORPHINE SULFATE (mor-pheen) Oral Solution (CII)

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1 Medicatin Guide MORPHINE SULFATE (mr-pheen) Oral Slutin (CII) IMPORTANT: Keep Mrphine Sulfate Oral Slutin in a safe place away frm children. Accidental use by a child is a medical emergency and can cause death. If a child accidentally takes Mrphine Sulfate Oral Slutin, get emergency help right away. Read the Medicatin Guide that cmes with Mrphine Sulfate Oral Slutin befre yu start taking it and each time yu get a new prescriptin. There may be new infrmatin. This Medicatin Guide des nt take the place f talking with yur healthcare prvider abut yur medical cnditin r yur treatment. What is the mst imprtant infrmatin I shuld knw abut Mrphine Sulfate Oral Slutin? Mrphine Sulfate Oral Slutin can cause serius side effects, including death. Take Mrphine Sulfate Oral Slutin exactly as prescribed by yur healthcare prvider. If yu take the wrng dse r strength f Mrphine Sulfate Oral Slutin, yu culd verdse and die. It is especially imprtant when yu take Mrphine Sulfate Oral Slutin that yu knw exactly what dse and strength t take, and the right way t measure yur medicine. Yur healthcare prvider r pharmacist shuld shw yu the right way t measure yur medicine. Always use the ral syringe prvided with Mrphine Sulfate Oral Slutin, 100 mg per 5 ml (20 mg/ml) t help make sure yu measure the right amunt. The ral slutin cmes in several different dses (amunt f medicine per ml) and strengths (number f mgs). D nt take the strngest dse f Mrphine Sulfate Oral Slutin, 100 mg per 5 ml (20 mg/ml) unless yu are piid tlerant. Opiid tlerant means that yu have been regularly using Mrphine Sulfate Oral Slutin r anther piid medicine fr yur cnstant (arund the clck) pain and yur bdy is used t it. What is Mrphine Sulfate Oral Slutin? Mrphine Sulfate Oral Slutin is in a grup f drugs called narctic pain relievers. Mrphine Sulfate Oral Slutin is nly fr adults wh have mderate t severe pain. Mrphine Sulfate Oral Slutin is a prescriptin medicine that is used t manage mderate t severe pain that is expected t last a shrt perid f time (acute), and pain that cntinues arund-the-clck and is expected t last fr a lng perid f time (chrnic). Mrphine Sulfate Oral Slutin is a federally cntrlled substance (CII) because it is a strng piid pain medicine that can be abused by peple wh abuse prescriptin medicines r street drugs. Prevent theft, misuse r abuse. Keep Mrphine Sulfate Oral Slutin in a safe place t keep it frm being stlen. Mrphine Sulfate Oral Slutin can be a target fr peple wh misuse r abuse prescriptin medicines r street drugs. Never give Mrphine Sulfate Oral Slutin t anyne else, even if they have the same symptms yu have. It may harm them r even cause death. Selling r giving away this medicine is against the law. It is nt knwn if Mrphine Sulfate Oral Slutin is safe and effective in children under age 18 years f age. Mrphine Sulfate Oral Slutin 100 mg per 5 ml (20 mg/ml) is nly fr adults with mderate t severe pain wh are already using an piid narctic pain medicine and have been using this medicine cntinuusly fr several weeks r lnger. Wh shuld nt take Mrphine Sulfate Oral Slutin?

2 D nt take Mrphine Sulfate Oral Slutin if yu: are allergic t mrphine, mrphine salts r any f the ingredients in Mrphine Sulfate Oral Slutin. See the end f this Medicatin Guide fr a cmplete list f ingredients in Mrphine Sulfate Oral Slutin. are having an asthma attack r have severe asthma, truble breathing, r lung prblems have a bwel blckage called paralytic ileus What shuld I tell my healthcare prvider befre taking Mrphine Sulfate Oral Slutin? Befre taking Mrphine Sulfate Oral Slutin, tell yur healthcare prvider if yu: have truble breathing r lung prblems have had a head injury have liver r kidney prblems have had adrenal gland prblems, such as Addisn s disease have severe sclisis that affects yur breathing have thyrid prblems have prblems urinating r enlargement f yur prstate have had cnvulsins r seizures have a past r present drinking prblem r alchlism have severe mental prblems r hallucinatins (seeing r hearing things that are nt really there) have cnstipatin r ther bwel prblems have prblems with yur pancreas r gallbladder have past r present substance abuse r drug addictin plan t have surgery have any ther medical cnditins are pregnant r plan t becme pregnant. It is nt knwn if Mrphine Sulfate Oral Slutin will harm yur unbrn baby. Talk t yur healthcare prvider if yu are pregnant r plan t becme pregnant. If yu take Mrphine Sulfate Oral Slutin regularly befre yur baby is brn, yur newbrn baby may have withdrawal symptms because their bdy has becme used t the medicine. Symptms f withdrawal in a newbrn baby may include: irritability being very active prblems sleeping high pitched cry shaking (tremrs) vmiting diarrhea r mre stls than nrmal weight lss fever If yu take Mrphine Sulfate Oral Slutin right befre yur baby is brn, yur baby culd have breathing prblems. are breast-feeding r plan t breast-feed. Sme mrphine sulfate passes int yur breast milk. A nursing baby culd becme very sleepy and have prblems breathing r feeding well. If yu stp breast-feeding, yur baby may have withdrawal symptms. See the list f withdrawal symptms abve. Yu and yur healthcare prvider shuld decide if yu will take Mrphine Sulfate Oral Slutin r breast-feed.

3 Tell yur healthcare prvider abut all the medicines yu take, including prescriptin and nn-prescriptin medicines, vitamins, and herbal supplements. Smetimes the dses f medicines that yu take with Mrphine Sulfate Oral Slutin may need t be changed if used tgether. Be especially careful abut taking ther medicines that make yu sleepy such as: Ask yur healthcare prvider if yu are nt sure if yur medicine is ne listed abve. Knw the medicines yu take. Keep a list f them and shw it t yur healthcare prvider and pharmacist when yu get a new medicine. Hw shuld I take Mrphine Sulfate Oral Slutin? sleeping pills ther pain medicines anti-nausea medicines tranquilizers muscle relaxants antihistamines anti-anxiety medicines antidepressants antichlinergic medicines antibitic r antifungal medicines heart medicines anti-seizure medicines Tell yur healthcare prvider if yu take cimetidine (Tagamet). D nt take Mrphine Sulfate Oral Slutin if yu already take a mnamine xidase inhibitr medicine (MAOI) r within 14 days after yu stp taking an MAOI medicine. D nt take any new medicine while using Mrphine Sulfate Oral Slutin until yu have talked with yur healthcare prvider r pharmacist. They will tell yu if it is safe t take ther medicines with Mrphine Sulfate Oral Slutin. See What is the mst imprtant infrmatin I shuld knw abut Mrphine Sulfate Oral Slutin? Take Mrphine Sulfate Oral Slutin exactly as prescribed. D nt change yur dse unless yur healthcare prvider tells yu t. Yur healthcare prvider may change yur dse after seeing hw the medicine affects yu. Call yur healthcare prvider if yur pain is nt well cntrlled with yur prescribed dse f Mrphine Sulfate Oral Slutin. Yu can take Mrphine Sulfate Oral Slutin with r withut fd. Make sure yu understand exactly hw t measure yur dse. Always use the ral syringe prvided with yur Mrphine Sulfate Oral Slutin, 100 mg per 5 ml (20 mg/ml) t help make sure yu measure the right amunt. See the Instructins fr Use at the end f this Medicatin Guide fr infrmatin abut hw t measure yur dse the right way. Ask yur healthcare prvider r pharmacist if yu are nt sure what dse f Mrphine Sulfate Oral Slutin yu shuld take r if yu are nt sure hw t use the ral syringe. D nt stp taking Mrphine Sulfate Oral Slutin suddenly. If yu have been taking Mrphine Sulfate Oral Slutin fr mre than a few weeks, stpping Mrphine Sulfate Oral Slutin suddenly can make yu sick with withdrawal symptms (fr example, nausea, vmiting, diarrhea, anxiety, and shivering). If yur healthcare prvider decides yu n lnger need Mrphine Sulfate Oral Slutin, ask hw t slwly reduce this medicine. D nt stp taking Mrphine Sulfate Oral Slutin withut talking t yur healthcare prvider. If yu miss ne dse f Mrphine Sulfate Oral Slutin yu can take the dse when yu remember it if yu have pain, r yu can wait fr the next dse. Talk with yur healthcare prvider regularly abut yur pain t see if yu still need t take Mrphine Sulfate Oral Slutin.

4 What shuld I avid while taking Mrphine Sulfate Oral Slutin? Yu shuld nt drink alchl while using Mrphine Sulfate Oral Slutin. Drinking alchl with Mrphine Sulfate Oral Slutin may increase yur risk f having dangerus side effects r death. D nt drive, perate heavy machinery, r d ther dangerus activities, especially when yu start taking Mrphine Sulfate Oral Slutin and when yur dse is changed, until yu knw hw Mrphine Sulfate Oral Slutin affects yu. Mrphine Sulfate Oral Slutin can make yu sleepy. Ask yur healthcare prvider t tell yu when it is kay t d these activities. What are the pssible side effects f Mrphine Sulfate Oral Slutin? See What is the mst imprtant infrmatin I shuld knw abut Mrphine Sulfate Oral Slutin? Mrphine Sulfate Oral Slutin can cause serius breathing prblems that can becme life-threatening, especially if Mrphine Sulfate Oral Slutin is used the wrng way. Call yur healthcare prvider r get help right away if: yur breathing slws dwn yu have shallw breathing (little chest mvement with breathing) yu feel faint, dizzy, cnfused, r yu have any ther unusual symptms These can be symptms that yu have taken t much Mrphine Sulfate Oral Slutin (verdse) r the dse is t high fr yu. These symptms may lead t serius prblems r death if nt treated right away. Mrphine Sulfate Oral Slutin can cause yur bld pressure t drp. This can make yu feel dizzy if yu get up t fast frm sitting r lying dwn. Lw bld pressure is als mre likely t happen if yu take ther medicines that can als lwer yur bld pressure. Severe lw bld pressure can happen if yu lse bld r take certain ther medicines. There is a risk f abuse r addictin with Mrphine Sulfate Oral Slutin. The chance is higher if yu are r have been addicted t r abused ther medicines, street drugs, r alchl, r if yu have a histry f mental prblems. Mrphine Sulfate can cause physical dependence. D nt stp taking Mrphine Sulfate r any ther piid withut talking t yur healthcare prvider abut hw t slwly stp yur medicine. Yu culd becme sick with uncmfrtable withdrawal symptms because yur bdy has becme used t these medicines. Physical dependence is nt the same as drug addictin. Tell yur healthcare prvider if yu have any f these symptms f withdrawal while slwly stpping Mrphine Sulfate Oral Slutin: feel restless tearing eyes runny nse yawning sweating chills r hair n yur arms stand up muscle aches, backache dilated pupils f yur eyes feel irritable r anxius truble sleeping nausea, lss f appetite, vmiting, diarrhea, stmach-area (abdminal) cramps increase in yur bld pressure faster breathing, r faster heart beats Cmmn side effects f Mrphine Sulfate Oral Slutin include:

5 Cnstipatin Nausea Sleepiness Lightheadedness Dizziness Drwsiness Vmiting sweating Cnstipatin (nt ften enugh r hard bwel mvements) is a very cmmn side effect f pain medicines (piids). Talk t yur healthcare prvider abut dietary changes, and the use f laxatives (medicines t treat cnstipatin) and stl sfteners t prevent r treat cnstipatin while taking Mrphine Sulfate Oral Slutin. Tell yur healthcare prvider if yu have any side effect that bthers yu r that des nt g away. These are nt all the pssible side effects f Mrphine Sulfate Oral Slutin. Fr mre infrmatin, ask yur healthcare prvider r pharmacist. Call yur dctr fr medical advice abut side effects. Yu may reprt side effects t FDA at FDA Hw shuld I stre Mrphine Sulfate Oral Slutin? Stre Mrphine Sulfate Oral Slutin at 68º t 77º F (20º t 25º C). After yu stp taking Mrphine Sulfate Oral Slutin, flush the unused ral slutin dwn the tilet. Keep Mrphine Sulfate Oral Slutin ut f the reach f children. Accidental verdse by a child is a medical emergency and can lead t death. General infrmatin abut Mrphine Sulfate Oral Slutin Medicines are smetimes prescribed fr purpses ther than thse listed in a Medicatin Guide. D nt use Mrphine Sulfate Oral Slutin fr a cnditin fr which it was nt prescribed. D nt give yur Mrphine Sulfate Oral Slutin t ther peple, even if they have the same symptms yu have. Selling r giving away Mrphine Sulfate Oral Slutin may harm thers, may cause death, and is against the law. This Medicatin Guide summarizes the mst imprtant infrmatin abut Mrphine Sulfate Oral Slutin. If yu wuld like mre infrmatin, talk with yur healthcare prvider. Yu can ask yur healthcare prvider r pharmacist fr infrmatin abut Mrphine Sulfate Oral Slutin that is written fr healthcare prfessinals. Fr mre infrmatin abut Mrphine Sulfate Oral Slutin, g t r call What are the ingredients in Mrphine Sulfate Oral Slutin? Active ingredient: mrphine sulfate Inactive ingredients: citric acid, edetate disdium, glycerin, sdium benzate, srbitl, and water. This Medicatin Guide has been apprved by the U.S. Fd and Drug Administratin. Manufactured By Minneaplis, MN L800 RC J1 Rev D

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