Analytical Aspects of Mycotoxin Binders
|
|
- Sydney Osborne
- 6 years ago
- Views:
Transcription
1 Fusarium-toxin Forum of 1-2 February Joint Research Centre (JRC) Analytical Aspects of Mycotoxin Binders Anna Kolossova & Joerg Stroka
2 Overview Fusarium-toxin Forum of 1-2 February Legal background Type of Binders (structure) Binders available to test in the study Design/outline of study and evaluation Analytical methods used Statistical evaluation Conclusion
3 Legislation first Fusarium-toxin Forum of 1-2 February
4 Some background Fusarium-toxin Forum of 1-2 February My first contact with binders Macaws in Peru Munn, C.A., Macaws: winged rainbows. Natl. Geograph. 185: TD Phillips is working with Don Brightsmith, Head of Rainforest Expeditions, to determine the reason for geophagy in Macaws in Peru. Humans in Ghana
5 What has research been focussed on? Fusarium-toxin Forum of 1-2 February Animal health (in vivo) Metabolic indicators (in vivo) Cell culture studies (in vitro) Isotherm studies (analysis of suspensions) Effects on analysis????
6 Methods for prevention and decontamination of mycotoxins Fusarium-toxin Forum of 1-2 February Prevention of mycotoxin contamination Pre- and post-harvest control and harvest management Codex Alimentarius codes of practice for the prevention and reduction of mycotoxins in cereals, peanuts, apple products, raw materials The use of HACCP to consider in the future Although the prevention of mycotoxin contamination in the field is the main goal of agricultural and food industries, under certain environmental conditions the contamination of various commodities with mycotoxins is unavoidable Detoxification of mycotoxins Removal from contaminated commodities Inactivation of mycotoxins by physical, chemical or biological methods Neither the use of chemical decontamination processes, nor the mixing of batches with the aim of decreasing the level of contamination below the maximum tolerable level are legal within the EU Mycotoxins can not be entirely eliminated
7 Mycotoxin binders Fusarium-toxin Forum of 1-2 February A mycotoxin binder (adsorbent/denaturant) added to the diet should be able to interact in vivo with mycotoxins and restrict their absorption in the GI tract of animals Several requirements for a mycotoxin binder Effective inactivation of mycotoxins of interest Reduction of mycotoxin bioavailability/activity Availability of essential nutrients to an animal Not being detrimental to animal or food product Not being a growth promoter (growth promotion may mask mycotoxins) Demonstrate verifiable positive results (improvement of zootechnical performance; recovery of organ status; excretion of mycotoxins via faeces; recovery of the immune status) Technical and economical feasibility
8 Types of Mycotoxin Binders Fusarium-toxin Forum of 1-2 February Adsorbents Inorganic Activated charcoal Aluminosilicates, clays HSCAS, bentonite, montmorillonite, zeolite, clinoptilolite Clay minerals layered silicates [Si 2 O 5 2- ] xy Zeolite silicate made of tetrahedrons of SiO 4 and AlO 4 Chemically treated silicates Organic Chemical polymers (cholestyramine, polyvinylpyrrolidone, divinylbenzene-styrene polymers ) High costs Glucan products Yeast and products from yeast (yeast cell wall)
9 Types of Mycotoxin Binders Fusarium-toxin Forum of 1-2 February Denaturant Mycotoxin-degrading enzymes Life microorganisms producing mycotoxin-degrading enzymes Eubacterium sp. (BBSH 797) T. mycotoxinivorans Organic binders Efficient against a larger range of mycotoxins than inorganic binders More adapted to the most frequent cases of multi-contaminated feeds Biodegradable and do not accumulate in the environment after being excreted by animals
10 Oltipraz a Mycotoxin Binder? Fusarium-toxin Forum of 1-2 February
11 Level of Interest for Testing Mycotoxin Binders Fusarium-toxin Forum of 1-2 February
12 Level of Interest for Testing Mycotoxin Binders Fusarium-toxin Forum of 1-2 February
13 Analytical aspects Fusarium-toxin Forum of 1-2 February Cascade of modern analytical Methods: Extraction Clean-up / Dilution Separation Detection
14 Methods used for testing Fusarium-toxin Forum of 1-2 February Official Methods (or those in standardization process): Aflatoxin B1 EN ISO 17375:2006 Deoxynivalenol pren 15791:2009 Zearalenone pren 15792:2009 Ochratoxin A WD N954 of TC327/WG1 Fumonisins WD N953 of TC327/WG1 T2 and HT2 toxins Breidbach et.al. under consideration as a prospective CEN standard.
15 Repeatability Data of the Test Methods Fusarium-toxin Forum of 1-2 February Mycotoxin DON AFB1 ZEA T2 & HT2 toxins FUM B1 + B2 OTA Average RSD r (%)
16 Tested Binders in this Study Fusarium-toxin Forum of 1-2 February Code Type of main product(s) ph value Amount added [%] 1 Yeast cell wall Clay + organic acid Clay Clay Yeast cell wall Yeast cell wall Yeast cell wall Mixture organic + mineral Yeast cell wall Mixture organic + mineral component Mixture organic + mineral component Clay Clay Fibres Montmorillonite Montmorillonite HSCAS HSCAS HSCAS Fibres (lignocellulose)
17 Some Statistics Fusarium-toxin Forum of 1-2 February Data analysis Student s t-test (independent two-sample t-test with unequal sample sizes and equal variance). Differences were assumed to be significant at p < Critical t-values (p = 0.05) were compared with those obtained by the Student s t-test according to the following formula: t = S X1 X n1 n2 Statistical Advisor: A. Breidbach
18 Aflatoxin B1 Fusarium-toxin Forum of 1-2 February Retrieval of aflatoxin B 1, % Binder
19 DON Fusarium-toxin Forum of 1-2 February Retrieval of deoxynivalenol, % Binder
20 ZON (combined binders) Fusarium-toxin Forum of 1-2 February Retrieval of zearalenone, % A B C D E Binder group
21 OTA (combined binders) Fusarium-toxin Forum of 1-2 February Retrieval of ochratoxin A, % A B C D E Binder group
22 Fumonisins (combined binders) Fusarium-toxin Forum of 1-2 February Retrieval of fumonisins B 1 & B 2, % A B C D E Binder group
23 T-2 & HT-2 toxins Fusarium-toxin Forum of 1-2 February Retrieval of T-2 & HT-2 toxins, % A B C D E Binder group
24 Recent Findings (FAC-A) on AfB1 Fusarium-toxin Forum of 1-2 February
25 Recent Findings (FAC-A) on DON Fusarium-toxin Forum of 1-2 February
26 AfB1 to AfM1 transformation in the presence of binders Fusarium-toxin Forum of 1-2 February
27 Conclusion Fusarium-toxin Forum of 1-2 February The addition of the tested binders (at the level indicated by the manufacturer) did not result in lower analytical values for any mycotoxin currently regulated in feed. The combined effect of processing such as wet heating, ph-change, etc. in the presence of mycotoxin binders was not investigated, but might be a subject of interest for other studies.
28 Collaborators Fusarium-toxin Forum of 1-2 February 2010 Ouissam Abbas and Vincent Baeten In collaboration with Alexandro Rodriguez Walloon Agricultural Research Centre Quality of Agricultural Products Department Chaussée de Namur, 24 B 5030 GEMBLOUX Tél :++ 32 (0) 81/ Fax : (0) 81/ baeten@cra.wallonie.be 28
29 IRMM staff behind the scene Fusarium-toxin Forum of 1-2 February 2010 Massimo Ambrosio Katy Kroeger Katrien Bouten 29
30 Open Call for Collaborators Fusarium-toxin Forum of 1-2 February IRMM is looking for collaborators for projects on: characterisation studies homogeneity and stability studies, and feasibility studies As well as for scientific staff (e.g. post docs)
Evaluation of the Effect of Mycotoxin Binders in Animal Feed on the Analytical Performance of Standardised Methods for
Evaluation of the Effect of Mycotoxin Binders in Animal Feed on the Analytical Performance of Standardised Methods for the Determination of Mycotoxins in Feed Follow-up study A. Kolossova, J. Stroka, A.
More informationFEED ADDITIVES FOR MYCOTOXIN DETOXIFICATION EFFICACY & AUTHORISATION
FEED ADDITIVES FOR MYCOTOXIN DETOXIFICATION EFFICACY & AUTHORISATION This article provides an overview of the different types of additives intended for use in animal feed for mycotoxin detoxification,
More informationFree-Tox. No escape THE POLYVALENT MYCOTOXIN BINDER
Free-Tox No escape THE POLYVALENT MYCOTOXIN BINDER no escape the polyvalent mycotoxin binder 2 nnmycotoxins and moulds Mycotoxins are secondary metabolites produced by moulds growing on crops in the field
More informationEuropean Commission Fusarium mycotoxins Forum Brussels 9 10 February Update on Fusarium mycotoxins - data from the starch industry
European Commission Fusarium mycotoxins Forum Brussels 9 10 February 2009 Update on Fusarium mycotoxins - data from the starch industry 1 Outline presentation 1. The European Starch Industry 2. Data on
More informationFusarium-toxins. Frans Verstraete European Commission DG Health and Consumer Protection
Fusarium-toxins Frans Verstraete European Commission DG Health and Consumer Protection 1 Provisions Fusarium-toxins - Food Provisions as regards the presence of deoxynivalenol, zearalenone, fumonisins
More informationReport of the first Inter-Laboratory Comparison Test organised by the Community Reference Laboratory for Mycotoxins
Report of the first Inter-Laboratory Comparison Test organised by the Community Reference Laboratory for Mycotoxins Aflatoxins B 1, B 2, G 1 & G 2 in acetonitrile Joerg Stroka, Andreas Breidbach, Ivanka
More informationEuropean Commission Fusarium mycotoxins Forum Brussels January 2007
European Commission Fusarium mycotoxins Forum Brussels 15-16 January 2007 Impact of the proposed limits of Fusarium mycotoxins in maize for the starch industry AAF main facts and figures: 24 companies
More informationMycotoxin Detection & Solutions
BANFF PORK SEMINAR Mycotoxin Detection & Solutions Don Giesting, Ph.D. Provimi NA/Cargill Animal Nutrition 1 Cargill Incorporated. All Rights Reserved. Mycotoxins Mycotoxins are metabolites of molds Stresses
More informationFood Safety Risk Assessment and Risk Management at a European Level
Food Safety Risk Assessment and Risk Management at a European Level John Gilbert Central Science Laboratory EFSA CONTAM Panel 2002-2006 SELAMAT Seminar 24 th April 2006 Outline of Talk Introduction Risk
More informationMycotoxin Detection and Solutions
Mycotoxin Detection and Solutions Donald W. Giesting, Ph.D. Provimi North America/Cargill Animal Nutrition 15407 McGinty Road West, MS 14, Wayzata, MN 55391, USA Don_giesting@cargill.com 1. Introduction
More informationMycotoxins in high moisture grain silages and ensiled grain by-products
Mycotoxins in high moisture grain silages and ensiled grain by-products Frank Driehuis NIZO food research, Ede, The Netherlands frank.driehuis@nizo.com July 3rd, 2015 XVII ISC 2015 - Piracicaba Brazil
More informationMycotoxin challenge in aquaculture feed. Maarten Jay van Schoonhoven, Aqua Care Manager Olmix
Mycotoxin challenge in aquaculture feed Maarten Jay van Schoonhoven, Aqua Care Manager Olmix mjvanschoonhoven@olmix.com THE MYCOTOXIN CHALLENGE Challenges of using plant ingredients Proteins of plant origin:
More informationMycocheck Survey 2014
Mycocheck Survey 14 INTRODUCTION Mycotoxins are secondary metabolites produced by moulds that have the capacity to impair animal health and productivity. Contamination of forages and cereals with mycotoxins
More informationSCIENTIFIC OPINION. EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) 2,3
SCIENTIFIC OPINION Statement on the establishment of guidelines for the assessment of additives from the functional group substances for reduction of the contamination of feed by 1 EFSA Panel on Additives
More informationMycotoxins and Poultry Health Natacha S. Hogan
Mycotoxins and Poultry Health Natacha S. Hogan Department of Animal and Poultry Science, University of Saskatchewan, Saskatoon, SK Toxicology Centre, University of Saskatchewan, Saskatoon, SK Outline Fusarium
More informationMycotoxins, MRL s & food chain contaminations
1 Mycotoxins, MRL s & food chain contaminations IAOM-MEA, 15.11.2008, Arusha Ir. Johny Boerjan Hazards associated with wheat & wheat processing (HACCP) Physical hazards Glass, stones, metal, Biological
More informationBinders-premixture for all species of animals
Binders-premixture for all species of animals Technological additives/kg: Kieselgur, diatomaceous earth, purified Bentonite Kaolinitic clays, free of asbestos Natural mixtures of steatites and chlorite
More informationProSid TM. Making a difference in fighting mould problems. Feed additives that give key benefits
ProSid TM Making a difference in fighting mould problems Feed additives that give key benefits Strong effect against mould Broad spectrum of activity Preserve full nutritional value of feed Adsorption
More informationVarious Impacts of Mycotoxins on Turkey Health and Performance
Journal of Food Science and Engineering 8 (2018) 97-101 doi: 10.17265/2159-5828/2018.02.006 D DAVID PUBLISHING Various Impacts of Mycotoxins on Turkey Health and Performance Radka Borutova Nutriad International,
More informationMycotoxins in the Poultry Industry
Mycotoxins in the Poultry Industry Tom A. Scott, Ph. D. Research Chair in Feed Processing technology Coll.: Michael Kautzman, M. Sc. Candidate, Toxicology University of Saskatchewan www.usask.ca www.usask.ca
More informationThe 2009 Wisconsin Corn Crop
The 2009 Wisconsin Corn Crop High Moisture Corn, Aerobic Stability, Feed Additives and Mycotoxins Common Questions Patrick Hoffman 1, Randy Shaver 1 and Paul Esker 2 University of Wisconsin-Extension 1
More informationMonitoring & Surveillance Series
CHEMICAL Monitoring & Surveillance Series Survey of Mycotoxins in Irish Grain Samples 212 TABLE OF CONTENTS SUMMARY... 2 INTRODUCTION... 3 Fusarium Toxins... 3 Aflatoxins... 4 STUDY OUTLINE... 4 SAMPLING...
More informationOverview of Mycotoxins in India with special reference to Aflatoxins. F Waliyar
Overview of Mycotoxins in India with special reference to Aflatoxins F Waliyar Important Mycotoxins Aflatoxins Ochratoxins Fusarial toxins Fumonisins Zearalenone T2-toxin Deoxynivalenol Nivalenol Mycotoxin
More informationCOMMISSION IMPLEMENTING REGULATION (EU)
EN 31.10.2013 Official Journal of the European Union L 289/33 COMMISSION IMPLEMENTING REGULATION (EU) No 1060/2013 of 29 October 2013 concerning the of bentonite as a feed additive for all animal (Text
More informationThe Influence and Control of Mycotoxins in Feed Industry
1 1 2 2 1 200240 2 201200 The Influence and Control of Mycotoxins in Feed Industry CHEN Feng, Li Zhixian, Li Taixiang (1. School of Life Science and Technology, Shanghai Jiao Tong University, Shanghai
More informationRemoval of Mycotoxins during Food Processing
88 Removal of Mycotoxins during Food Processing Hisashi Kamimura Abstract In order to learn whether there might be a risk to human health from the intake of mycotoxins contaminating agricultural products,
More informationMYCOTOXIN PRODUCT LINE MULTI-RESIDUE MYCOTOXIN ANALYSIS PHOTOCHEMICAL REACTOR AUTOMATED SAMPLE CLEAN-UP IMMUNOAFFINITY SAMPLE CLEAN-UP ELISA TEST KITS
MULTI-RESIDUE MYCOTOXIN ANALYSIS PHOTOCHEMICAL REACTOR AUTOMATED SAMPLE CLEAN-UP IMMUNOAFFINITY SAMPLE CLEAN-UP ELISA TEST KITS MYCOTOXIN PRODUCT LINE MYCOTOXIN ANALYSIS PRODUCTS CATALYST FOR SUCCESS POST-COLUMN
More informationReview on mycotoxin risk
SAFE FOODS SEMINAR Budapest, 29 30 March 2007 Review on mycotoxin risk Prandini, A., Sigolo, S. and Filippi, L. Institute of Food Science and Nutrition - Catholic University of Piacenza MYCOTOXIN Secondary
More informationAccurate quantification of regulated mycotoxins by UHPLC-MS/MS and screening for 200+ mycotoxins in food and feed.
Accurate quantification of regulated mycotoxins by UHPLC-MS/MS and screening for 200+ mycotoxins in food and feed. John Lee Global Food Market Manager Mycotoxins Background } myces(greek) = fungus toxicum(latin)
More informationMYCOTOXINS IN AQUACULTURE
MYCOTOXINS IN AQUACULTURE OCCURRENCE AND IMPACT IN RAINBOW TROUT Rui A. Gonçalves (rui.goncalves@biomin.net) BIOMIN Holding, Austria 2017 by Erber AG, Austria. All rights reserved. Naturally ahead 2017
More informationAflatoxins and animal health: Case studies from Africa
Aflatoxins and animal health: Case studies from Africa Johanna Lindahl Christine Atherstone Delia Grace PACA workshop Engaging the Health and Nutrition Sectors in Aflatoxin Control in Africa Addis Ababa,
More informationEscent L. The optimal solution for maximum profitability
Escent L The optimal solution for maximum profitability Escent L The optimal solution for maximum profitability Metabolic disorders and disease symptoms caused by toxins. Practical and easy applicable
More informationJoint Research Centre
Joint Research Centre Futtermittelzusatzstoffe das EURL im Bereich der Zulassung Christoph von Holst 4.-5. November 2015: Vergleichbarkeit von Messergebnissen Analytik im Spannungsfeld globaler Warenströme
More informationPayback News. Capturing Value with Creep Feeding. protein, vitamins, and minerals, on pasture. When done correctly,
CHS NUTRITION Payback News April, 2015 In this issue of Payback News: Capturing Value with Creep Feeding Managing Mycotoxins in Grain and Forage Inside this issue: Capturing Value with Creep Feeding 2
More informationMycotoxin Analysis in Animal Feed by LC/MS/MS
Mycotoxin Analysis in Animal Feed by LC/MS/MS Wei Li, Susie Y. Dai, Timothy J. Herrman February 29, 2012 at OTSC Texas Feed and Fertilizer Control Service Agriculture Analytical Service Mycotoxins Mycotoxins
More informationRisk assessment of mycotoxins: the EFSA approach. Katleen Baert Scientific officer, EFSA
Risk assessment of mycotoxins: the EFSA approach Katleen Baert Scientific officer, EFSA International Conference The burden of Mycotoxins on animal and human health Rome, 15 December 2017 RECEIPT OF A
More informationFate of Fusarium Mycotoxins in Cereal Food Chain. Dr Clare Hazel, RHM Technology Mr Keith Scudamore, KAS Mycotoxins
Fate of Fusarium Mycotoxins in Cereal Food Chain Dr Clare Hazel, RHM Technology Mr Keith Scudamore, KAS Mycotoxins Presentation Aim To contribute data addressing the fate of Fusarium mycotoxins during
More informationMycotoxins in Turkeys
Management Article The premier supplier of turkey breeding stock worldwide NU15 Version 1 Mycotoxins in Turkeys Marcus Kenny, Company Nutritionist Aviagen Turkeys Ltd Many species of fungi produce secondary
More informationHelping the liver to detoxify mycotoxins
Helping the liver to detoxify mycotoxins Mycotoxin strategies have so far focused on binding compounds or detoxifying the compounds by feed additives. Animals however, can also detoxify mycotoxins themselves
More informationMycofix Secure Bentonite (dioctahedral montmorillonite) (FAD ; CRL/090044)
Ref. Ares(2013)179391-12/02/2013 EUROPEAN COMMISSION JOINT RESEARCH CENTRE Institute for Reference Materials and Measurements (Geel) Standards for Food Bioscience Unit European Union Reference Laboratory
More informationDRAFT EAST AFRICAN STANDARD
DEAS 44:2016 ICS 67.060 DRAFT EAST AFRICAN STANDARD Milled maize (corn) products Specification EAST AFRICAN COMMUNITY EAS 2016 First Edition 2016 Copyright notice This EAC document is copyright-protected
More informationInstituto Internacional de Investigación Animal, Querétaro, México, 2 Avimex, México, INTRODUCTION
EVALUATION OF THE EFFICACY OF A COMMERCIAL HYDRATED SODIUM CALCIUM ALUMINOSILICATE TO REDUCE THE TOXICITY OF AFLATOXIN AND OCHRATOXIN IN BROILER CHICKS. A. Casarin 1, M. Forat 1, E. Soto 2, M. Contreras*
More informationMYCOTOXIN PREVENTION CLUSTER
MYCOTOXIN PREVENTION CLUSTER Co-ordinator Prof. Naresh Magan Applied Mycology Group, Biotechnology Centre, Cranfield University, Silsoe, Bedford, UK MK45 4DT www.mycotoxin-prevention.com BACKGROUND 1 Evidence
More informationREGIONAL DIFFERENCES ON THE WORLDWIDE MYCOTOXIN OCCURRENCE. Copyright 2010 by Erber AG. Austria. All rights reserved.
REGIONAL DIFFERENCES ON THE WORLDWIDE MYCOTOXIN OCCURRENCE Mycotoxin Survey Program 2010 Occurrence of Mycotoxins in different regions Occurrence of Mycotoxins in different feedstuffs Method of analyses
More informationThe Significance of Feed-Borne Mycotoxins in Aquaculture
The Significance of Feed-Borne Mycotoxins in Aquaculture Abstract Trevor K. Smith Department of Animal and Poultry Science, University of Guelph, Guelph, Ontario, Canada, N1G 2W1 E-mail: tsmith@uoguelph.ca
More informationAflatoxins in Malaysian food
Mycotoxins Vol. 50, 2000 31 Aflatoxins in Malaysian food Norhayati ALl Introduction Aflatoxins (AF) are carcinogenic, teratogenic and mutagenic. Naturally occurring AF are Class 1 human carcinogens, particularly
More information(FAD ; CRL/160015)
EUROPEAN COMMISSION DIRECTORATE GENERAL JOINT RESEARCH CENTRE Directorate F Health, Consumers and Reference Materials European Union Reference Laboratory for Feed Additives Ref. Ares(2017)748021-10/02/2017
More informationReport on the 2007 Proficiency Test of the Community Reference Laboratory Network
Report on the 2007 Proficiency Test of the Community Reference Laboratory Network Determination of Aflatoxins in a Peanut Product and a Test Solution J. Stroka, A. Breidbach, I. Doncheva, M. Ambrosio 9
More informationMycotoxin Analysis in Food and Feed
Mycotoxin Analysis in Food and Feed Mycotoxins are toxic secondary metabolites produced by fungi (moulds). Mycotoxins can be formed in agricultural products, such as cereals, and can also occur in related
More informationICGMA Report Codex Committee on Contaminants in Foods Moscow, The Russian Federation 8 12 April 2013
ICGMA Report Codex Committee on Contaminants in Foods Moscow, The Russian Federation 8 12 April 2013 Executive Summary The 7 th session of the Codex Committee on Contaminants in Foods (CCCF) was held in
More informationNew SPE Sorbent for Clean-up of Fusarium Toxin-contaminated Cereals & Cereal-based Foods, Bond Elut Mycotoxin
New SPE Sorbent for Clean-up of Fusarium Toxin-contaminated Cereals & Cereal-based Foods, Application Note Fusarium Fungi, Cereals Authors Marianna Klötzel, Uwe Lauber Chemisches u. Veterinäruntersuchungsamt
More informationMycotoxin Petfood Binder
Welcome To: Ultrateck Laboratories Inc. Bio-Logics Aflatrol Mycotoxin Petfood Binder What is Aflatrol? Aflatrol is presently showing a high potential for aflatoxin mycotoxin binding in animal feeds and
More informationSlaven Zjalić, Department of ecology, agronomy and aquaculture, University of Zadar, Croatia
Slaven Zjalić, Department of ecology, agronomy and aquaculture, University of Zadar, Croatia Mycotoxins are secondary metabolites produced by some moulds Most of mycoxtoxins have no odor and no taste Through
More informationUNOFFICIAL TRANSLATION
UNOFFICIAL TRANSLATION MINISTERIAL REGULATION ON THE ESTABLISHMENT OF THAI AGRICULTURAL STANDARD ON PEANUT KERNEL: MAXIMUM LEVEL OF AFLATOXIN AS A MANDATORY STANDARD B.E. 2558 (2015) By virtue of Section
More informationOFFICE OF THE TEXAS STATE CHEMIST
OFFICE OF THE TEXAS STATE CHEMIST Texas Feed and Fertilizer Control Service Agricultural Analytical Service 445 Agronomy Road College Station, TX 77843-2114 Mailing Address P. O. Box 3160 College Station,
More informationDetection and elimination strategies of matrix effects. in quantitative multi-target LC-ESI-MS/MS analysis
Detection and elimination strategies of matrix effects in quantitative multi-target LC-ESI-MS/MS analysis David Steiner, Michael Sulyok, Leonardo Mariño Repizo, Lidija Kenjerić, Rudolf Krska MultiCoop
More informationFINAL DRAFT EAST AFRICAN STANDARD
FINAL DRAFT EAST AFRICAN STANDARD Milled maize (corn) products Specification EAST AFRICAN COMMUNITY ICS 67.060 EAC 2011 Second Edition 2011 Foreword Development of the East African Standards has been necessitated
More informationFor Client Review Only. All Rights Reserved. Advanstar Communications Inc Scarlett Biselli, Lutz Hartig, Heiner Wegner, and Christian Hummert
Analysis of Fusarium Toxins Using LC MS-MS: Application to Various Food and Feed Matrices Co-occurrence of several mycotoxins (deoxynivalenol, zearalenone, T-2-toxin, HT-2 toxin) produced by field fungi,
More informationGuidance on the application of Commission Recommendation 2013/165/EU on the presence of T-2 and HT-2 toxin in cereals and cereal products
Guidance on the application of Commission Recommendation 2013/165/EU on the presence of T-2 and HT-2 toxin in cereals and cereal products UK Stakeholder Group 6 th September 2013 Presented by Susan MacDonald
More informationAssessment of mycotoxins in grains and oilseeds most consumed in Ivory Coast
Assessment of mycotoxins in grains and oilseeds most consumed in Ivory Coast D. Montet, L. Manizan, M. Oplatowska-Stachowiak, I. Metayer, D. Akaki, K. Campbell, C. Brabet didier.montet@cirad.fr Major grains
More informationAnti-Mycotoxin Additives
Anti-Mycotoxin Additives EFFICACY OF MYCOAD AGAINST AFLATOXIN IN LAYERS EXPERIMENTAL PROTOCOL Caged ISA Brown layers already in production were transferred from a commercial farm to an experimental unit
More informationFrom risk assessment to risk management focus on contaminants. Frans Verstraete European Commission DG Health and Consumer Protection
From risk assessment to risk management focus on contaminants Frans Verstraete European Commission DG Health and Consumer Protection 1 GENERAL FOOD LAW Regulation (EC) 178/2002 of the European Parliament
More informationAflatoxin B1 in rice bran as feed material and following contamination of consumer milk in Sweden: case study
Aflatoxin B1 in rice bran as feed material and following contamination of consumer milk in Sweden: case study Alexey Solyakov, Tech Dr, PhD Dept of Chemistry, Environment & Feed Hygiene National Veterinary
More informationMycotoxin Testing Solutions
Mycotoxin Testing Solutions Mycotoxin Testing Solutions DON Fumonisin We Stand Behind Our Results AFLATOXIN is considered by many to be the most potent naturally-occurring carcinogen known. It has been
More informationApplication form BNN-lab approval
1) General information Lab name: Responsible person for organic samples: Street: Place and postal code: Country: VAT number: Phone: Email: Fax: Internet: Please find on the following pages the application
More information(FAD ; CRL/160042)
EUROPEAN COMMISSION DIRECTORATE GENERAL JOINT RESEARCH CENTRE Directorate F Health, Consumers and Reference Materials European Union Reference Laboratory for Feed Additives Ref. Ares(2017)2516958-17/05/2017
More informationMycotoxins and Toxicological Impact in Swine
Mycotoxins and Toxicological Impact in Swine James D. House Departments of Human Nutritional Sciences & Animal Science, 408 Human Ecology Building, University of Manitoba, Winnipeg, MB R3T 2N2; Email:
More informationT-2, HT-2 2 and deoxynivalenol (DON) in malting barley and malt
5 th EC Forum on Fusarium toxins. Brussels, January 10-11 th, 2008 T-2, HT-2 2 and deoxynivalenol (DON) in malting barley and malt Ian Slaiding Outline of presentation What is Euromalt Summary of evidence
More informationMinnesota Wheat Research and Promotion Council RESEARCH PROPOSAL GRANT APPLICATION (2-pages maximum)
Description of the proposal: Minnesota Wheat Research and Promotion Council RESEARCH PROPOSAL GRANT APPLICATION (2-pages maximum) Fusarium head blight (FHB), also called scab, is a major fungal disease
More informationVALIDATION REPORT Ochratoxin A ELISA (According to the Commission Regulation (EU) No 519/2014)
VALIDATION REPORT Ochratoxin A ELISA (According to the Commission Regulation (EU) No 519/2014) Beijerinckweg 18 NL-6827 BN Arnhem The Netherlands Phone: +31 26 363 0 364 info@europroxima.com 1. Introduction
More informationAnalysis and Risk Assessment of New Mycotoxins
Technische Universität München Analysis and Risk Assessment of New Mycotoxins Michael Rychlik Technical University Munich, Germany University of Queensland, Australia Food Sure Amsterdam, 24.05.2017 Outline
More informationSCREENING FOR FUNGAL AND BACTERIAL METABOLIES USING QTRAP TECHNOLOGY
SCREENING FR FUNGAL AND BACTERIAL METABLIES USING QTRAP TECNLGY Michael Sulyok Center for Analytical Chemistry Department IFA-Tulln University of Natural Resources and Life Sciences Vienna Analytica 2016
More informationExtraction of Multiple Mycotoxins From Grain Using ISOLUTE Myco prior to LC-MS/MS Analysis
Application Note AN782 Extraction of Multiple Mycotoxins from Grain Using ISOLUTE Myco Page 1 Extraction of Multiple Mycotoxins From Grain Using ISOLUTE Myco prior to LC-MS/MS Analysis This application
More informationEAST AFRICAN STANDARD
ICS 67.060 EAST AFRICAN STANDARD Soya protein products Specification EAST AFRICAN COMMUNITY EAS 2013 First Edition 2013 Copyright notice This EAC document is copyright-protected by EAC. While the reproduction
More informationEFSA mycotoxin occurrence, data request & exposure assessment
EFSA mycotoxin occurrence, data request & exposure assessment Nada Jurišić BOKU, IFA-Tulln, Austria 20.09.2016 EFSA mycotoxin occurrence, data request & exposure assessment EFSA European Food Safety Authority
More information6 th EC Forum on Fusarium toxins. Brussels, February, 2009
6 th EC Forum on Fusarium toxins. Brussels, February, 2009 T-2, HT-2 and deoxynivalenol (DON) in malting barley and malt Ian Slaiding Outline of presentation What is Euromalt Summary of evidence presented
More informationMycotoxin Lesions in the Slaughter House-Broilers
Mycotoxin Lesions in the Slaughter House-Broilers SPECIAL NUTRIENTS, INC. THE MYCOTOXINS SPECIALIST www.mycotoxin.com INTRODUCTION Traditionally, the presence of mycotoxins capable of causing damage in
More informationAn integrated approach to mycotoxin testing in the poultry feed chain. Bankok, March 2010
An integrated approach to mycotoxin testing in the poultry feed chain Bankok, March 2010 OUTLINE Mycotoxins in poultry feed Integrated testing plan Sampling On-site testing Laboratory testing Mycotoxin
More informationmycotoxin-contaminated contaminated food or feed
Poisons in our Food By Melvin Newman, Ph.D. Professor Entomology and Plant Pathology Foods that may contain toxins Introduction Fungi: produce an array of chemical products called secondary metabolites.
More informationAnalysis of mycotoxins in food matrices using the Agilent Ultivo Triple Quadrupole LC/MS
Application Note Analysis of mycotoxins in food matrices using the Agilent Ultivo Triple Quadrupole LC/MS Figure 1. Agilent Ultivo Integrated into LC stack. Authors Theresa Sosienski 1, Dan Hui Dorothy
More informationTechnical Specifications for LNS-AM. -Lipid-based Nutrient Supplement for prevention of Acute Malnutrition-
Technical Specifications for LNS-AM -Lipid-based Nutrient Supplement for prevention of Acute Malnutrition- Specification reference: LNS category Version: V1.1 Date of issue: 20 August, 2012 1. INTRODUCTION
More informationRisk Assessment Studies Report No.5. Chemical Hazards Evaluation AFLATOXIN IN FOODS. April Food and Environmental Hygiene Department HKSAR
Risk Assessment Studies Report No.5 Chemical Hazards Evaluation AFLATOXIN IN FOODS April 2001 Food and Environmental Hygiene Department HKSAR 1 This is a publication of the Food and Public Health Branch
More informationRISKBENEFIT4EU PROJECT PARTNERING TO STRENGTHEN THE RISK- BENEFIT ASSESSMENT WITHIN EU USING A HOLISTIC APPROACH
RISKBENEFIT4EU PROJECT PARTNERING TO STRENGTHEN THE RISK- BENEFIT ASSESSMENT WITHIN EU USING A HOLISTIC APPROACH Ricardo Assunção, Carla Martins, Sílvia Viegas, Paulo Fernandes, Duarte Torres, Sarogini
More informationMycotoxins in Feed and Their Amelioration: A Review
JOURNAL OF ANIMAL NUTRITION AND PHYSIOLOGY Journal homepage: www.jakraya.com/journal/janp Mycotoxins in Feed and Their Amelioration: A Review MINI-REVIEW V.R. Patel., M. Choubey*, B.J. Trangadiya and A.P.
More informationEVALUATION OF MICROBIOLOGICAL PARAMETERS OF CEREALS EN ROUTE OF PRESERVATION PROCESS
C.D. Misca, et al. Scientifical Researches. Agroalimentary Processes and Technologies, Volume XI, No. 2 (2005), 451-456 EVALUATION OF MICROBIOLOGICAL PARAMETERS OF CEREALS EN ROUTE OF PRESERVATION PROCESS
More informationMycotoxins and metabolites, toxicity and implications
Berlin, June 21- Mycotoxins and metabolites, toxicity and implications Daniela Marin 1, Ionelia Taranu 1, Gina Manda 2 1 National Institute for Research and Development for Biology and Animal Nutrition,
More informationAPPLICATION NOTE Determination of Aflatoxin M1 via FREESTYLE ThermELUTE with Online HPLC-Measurement
Determination of Aflatoxin M1 via FREESTYLE ThermELUTE with Online HPLC-Measurement APPLICATION NOTE www.lctech.de As of: February 2017, Version: 1.3 Determination of Aflatoxin M1 via FREESTYLE ThermELUTE
More informationLab Services Sample Testing Information
Commitment to Excellence Today s food industry is growing rapidly as it tries to address the global food challenge. With this growth comes an increase in demand for diagnostic testing. Food producers are
More informationRisk management of mycotoxin presence in food products:major unsolved points
Ministero della Salute Risk management of mycotoxin presence in food products:major unsolved points Directorate General for food hygiene and safety and for nutrition Dr Monica CAPASSO Risk management Regulation
More informationOfficial Journal of the European Union COMMISSION
L 52/70 COMMISSION COMMISSION RECOMMDATION of 17 February 2004 on the coordinated inspection programme in the field of animal nutrition for the year 2004 in accordance with Council Directive 95/53/EC (Text
More informationResearch Proposal: Enterosorbent intervention therapies for populations at risk for Aflatoxin related diseases
Research Proposal: Enterosorbent intervention therapies for populations at risk for Aflatoxin related diseases Principal Investigator Timothy Phillips Texas A&M University College of Veterinary Medicine
More informationSUMMARY RECORD OF THE STANDING COMMITTEE ON THE FOOD CHAIN AND ANIMAL HEALTH HELD ON DECEMBER 2009 IN BRUSSELS (Section Animal Nutrition)
EUROPEAN COMMISSION HEALTH & CONSUMERS DIRECTORATE-GENERAL D(2009)411967 SUMMARY RECORD OF THE STANDING COMMITTEE ON THE FOOD CHAIN AND ANIMAL HEALTH HELD ON 17-18 DECEMBER 2009 IN BRUSSELS (Section Animal
More informationTechnical Specifications for the manufacture of: FORTIFIED NIXTAMALIZED MAIZE FLOUR HONDURAS AND RBP Local 1 Regional
Technical Specifications for the manufacture of: FORTIFIED NIXTAMALIZED MAIZE FLOUR HONDURAS AND RBP Local 1 Regional Commodity code: CERMML030 Version: 1, adopted 2018 Date of issue: 04.01.2018 Issued:
More informationVOL. 5, NO. 5, May 2015 ISSN ARPN Journal of Science and Technology All rights reserved.
Growth, Nutrient Digestibility of Broilers fed Aflatoxin Contaminated Diets with Aflatoxin Binders 1 A. D. Ologhobo, 2 E. O. Ewuola, 3 U. U. Jerome, 4 U. O. Franca, 5 O. Ifarajimi 1, 2,3,4,5 Poultry Research
More informationEffects of a Hydrated Sodium Calcium Aluminosilicate (T-Bind )on Mycotoxicosis in Young Broiler Chickens 1
Effects of a Hydrated Sodium Calcium Aluminosilicate (T-Bind )on Mycotoxicosis in Young Broiler Chickens 1 L. F., KUBENA,*,2 R. B. HARVEY,* R. H. BAILEY,* S. A. BUCKLEY,* and G. E. ROTTINGHAUS *USDA, Agricultural
More informationImproved Isolation and Analysis of Mycotoxins from Cereals, Beer and Wine
Improved Isolation and Analysis of Mycotoxins from Cereals, Beer and Wine Application Note Authors Elisabeth Korte, Maha Rudrabhatla, Max Erwine, Jason S Wood Agilent Technologies, Inc. Introduction Trichothecenes
More informationMATERIALS AND METHODS 68
emr00 ACSJCA JCA10.0.1408/W Unicode research.3f (R2.0.i4 HF02:2745 2.0 alpha 36) 2011/11/15 15:21:00 PROD-JCA1 rq_38148 12/19/2011 15:15:15 5 pubs.acs.org/jafc 1 Survey of Mycotoxins in U.S. Distiller
More informationAll Member States were represented except Cyprus and Lithuania.
EUROPEAN COMMISSION HEALTH & CONSUMERS DIRECTORATE-GENERAL D(2009)410772 SUMMARY RECORD OF THE STANDING COMMITTEE ON THE FOOD CHAIN AND ANIMAL HEALTH HELD IN BRUSSELS ON 19 JUNE 2009 SECTION "TOXICOLOGICAL
More informationTechnical requirements Nutrition products
Technical requirements Nutrition products Anna Kistauri Medicines and Nutrition Centre UNICEF Supply Division Nutrition Supplier Meeting 11 September 2013 Copenhagen Nutrition Unit Anthropometrics Supplementary
More informationAflatoxin Impacts on child growth Ahmed Kablan, PharmD, PhD. International Nutrition and Public Health Adviser
Aflatoxin Impacts on child growth Ahmed Kablan, PharmD, PhD. International Nutrition and Public Health Adviser Office of Agricultural Research and Policy Bureau for Food Security (BFS/ARP); USDA/ARS/Office
More information