Mid-term Outcomes of Arthroscopic-Assisted Core Decompression of Pre-collapse Osteonecrosis of Femoral Head Minimum of 5 Year Follow-up

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1 Arthroscopic-Assisted Core Decompression of Pre-collapse Osteonecrosis of Femoral Head Minimum of 5 Year Follow-up Mark R. Nazal*, Ali Parsa, Scott D. Martin Sports Medicine, Department of Orthopaedic Surgery Massachusetts General Hospital, Harvard Medical School Boston, MA, USA *Presenting Author: Mark R. Nazal Corresponding Author: Mark R. Nazal, mnazal@mgh.harvard.edu

2 Disclosures The authors have no disclosures, conflicts of interest, or competing interests to make.

3 Background Osteonecrosis of femoral head (ONFH): interrupted blood flow to femoral head Progressive disease Leads to collapse Development of Arthritis Numerous direct and indirect risk factors: corticosteroid use, excessive alcohol intake, and smoking Preferred management of ONFH remains controversial and is dependent on staging of the lesion Femoral head-preserving techniques have demonstrated successful outcomes in precollapsed stage lesions. Arthroscopic-assisted management of ONFH is a new and evolving approach for hip preservation. Purpose: To demonstrate that arthroscopy is able to improve ONFH by achieving accurate and minimally invasive decompression while successfully addressing concomitant intraarticular pathologies resulting in reliable mid-term outcomes.

4 Methods Retrospective cohort analysis of all patients who underwent hip arthroscopy between June 2007 and June 2013 Selection: Inclusion: hip arthroscopy for ONFH, patients with radiographic findings of Stage 0, I, IIa, and IIB (pre-collapse) based on Ficat-Alret classification for OFNH, and followup of a minimum of 5-years Exclusion: traumatic ONFH, Stage III or greater severity based on the Ficat-Alret classification, dysplastic hips, or complication of consumptive disease Outcomes: Conversion to THA Correlation analysis with Ficat-Alret classification, presence of mechanical symptoms, risk factors of ONFH, or bilateral involvement Concomitant hip pathology identified and treated during hip arthroscopy Complications

5 (a) (b) (a) Preoperative plain AP X-ray of left hip demonstrating a Stage IIa osteonecrotic lesion (b) MRI T1- weighted coronal image of left hip shows a geographic pattern of the necrotic area

6 Results Total cohort: 11 hips (8 patients) Mean patient follow-up: 7 years ± 1.48 years (range, months) Ficat-Alret classification: Stage I 3 (27.2%) Stage IIa 4 (36.4%) Stage IIb 4 (36.4%) Mechanical Issues: 4 (36.4%) (locking, catching, and buckling) Concomitant Pathology Addressed: Labral repair/debridement 8 (73%) Microfracture 7 (64%)

7 Results Final follow-up: 6 hips (54.5%) had not converted to THA Upon further stratification: Stage I 100%, Stage IIa 75%, for a combined 87%, had not converted to THA In contrast, 100% of hips categorized as Stage IIb had converted to THA. Ficat-Alret staging, especially Stage IIb, was significantly associated with conversion to THA. (p-value = 0.015) Complications major or minor: 0 (0%) ** = p<0.05

8 Conversion to THA THA No THA p-value Mechanical Symptoms 1/4 3/ Ficat-Alret Stage: 0.03* Stage I 0/3 3/ Stage IIa 1/4 3/ Stage IIb 4/4 0/ * Risk Factors: Inhaled Corticosteroid 2/2 0/ Smoking Tobacco 2/4 2/ Bilateral Hip Involvement 2/6 4/ Mechanical symptoms include locking, catching, and buckling. Statistical testing was conducted using Fisher s Exact Test for correlation of categorical variables. A p-value less than 0.05 indicated a significant difference.

9 Plain AP pelvis X-ray 5 years follow-up Stage IIa lesion Shows preserved joint space without lesion progression

10 Limitations Despite longer follow-up compared to similar existing studies: Has a small sample size and further investigation with larger cohorts is necessary There was no comparison group because all patients that presented with ONFH were treated similarly, there was no cohort of patients treated with non-arthroscopically assisted core decompression There are no patient-reported outcome measurements available However, we believe that this study is contributing to the literature by providing the first report of mid-term follow-up in arthroscopically managed ONFH patients.

11 Conclusion To our knowledge, this is the longest reported follow-up of arthroscopic-assisted management of ONFH An average of 7 years follow-up High survivability for Stage I (100%) and Stage IIa (75%) lesions While a 100% of Stage IIb lesions progressed to THA Treatment of the entire hip joint by addressing concomitant intraarticular pathologies Arthroscopic-assisted management is a promising surgical approach that provides safe, accurate, and minimally invasive decompression Resulting in reliable results with an acceptable conversion rate to THA

12

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