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1 Original Articles 2005/6/7 Wilkinson JM, Eagleton AC, Stockley I, Peel NFA, Hamer AJ, Eastell R. Effect of pamidronate on bone turnover and implant migration after total hip arthroplasty: a randomised trial. J Ortho Research 2005:23;1-8 Gluer CC, Eastell R, Reid DM Kolta S. Reply Risk assessment and fracture discrimination by ultrasound: the debate continues. J Bone Min Res 2005, vol 20 : 3 ; Siminoski K, Jiang G, Adachi JD.Eastell R. Accuracy of height loss during prospective monitoring for detection of incident vertebral fractures. Osteo Int 2005, vol 16: Delmas P, van de Langerijt L, Watts NB, Eastell R,.. Cahall D for the IMPACT Study Group. Underdiagnosis of vertebral fractures is a worldwide problem: The IMPACT Study. J Bone Min Res 2005, vol 20:4, Wilkinson JM, Hamer AJ, Stockley I, Eastell R. Polyethylene wear rate and osteolysis: critical threshold versus continuous dose-response relationship. J Ortho Research 2005:23; Ingle BM, Machado AB, Pereda CA, Eastell R. Monitoring alendronate therapy with quantitative ultrasound and bone mineral density. J Clin Densitometry 2005, vol 8:3: Siris ES, Harris ST, Eastell R, Zanchetta JR Cummings SR for the Continuing Outcomes Relevant to Evista (CORE) Study. Skeletal effects of raloxifene after 8 years: Results from the Continuing Outcomes Relevant to Evista (CORE) Study. J Bone Miner Res 2005, vol 20:9; Lemos MC, Kotanko P, Christie PT, Harding B, Javor T, Smith C, Eastell R, Thakker RV. A novel EXT1 splice site mutation in a kindred with hereditary Multiple exostosis and osteoporosis. J Clin Endo Metab 2005, vol 90(9): Clowes JA, Eastell R, Peel NF. The discriminative ability of peripheral and axial bone measurements to identify proximal femoral, vertebral, distal forearm and proximal humeral fractures: A case control study. Osteo Int 2005, vol 16:12; Paggiosi MA, Blumsohn A, Barkmann R, Eastell R. Effect of temperature on the Longitudinal variability of quantitative ultrasound variables. J Clin Densitometry 2005, vol 8:4;

2 Eastell R, Krege JH, Chen P, Glass EV, Reginster JY. Development of an algorithm for using P1NP to monitor treatment of patients with teriparatide. Current Medical Research and Opinions 2006, vol 22:1;61-66 Merza Z, Blumsohn A, Mah PM, Meads DM, McKenna SP, Wylie K, Eastell R, Wu F. Double-blind placebo-controlled study of testosterone patch therapy on bone turnover in men with borderline hypogonadism. Int J Androl 2006, Veitch SW, Findlay SC, Hamer AJ, Blumsohn A, Eastell R, Ingle BM. Changes in bone mass and bone turnover following tibial shaft fracture. Osteo Int 2006, vol 17: Shetty NR, Hamer AJ, Kerry RM, Stockley I, Eastell R, Wilkinson JM. Bone remodeling around a cemented polyethylene cup. J Bone & Joint Surgery 2006, vol 88:4; Smith CM, Coombs RC, Gibson AT, Eastell R. Adaptation of the Carter method to adjust lumbar spine bone mineral content for age and body size: application to children who were born preterm. J Clin Densitometry 2006, vol 9:1; Melton LJ III, Wenger DE, Atkinson EJ, Achenback SJ, Berquist TH, Riggs BL, Jiang G, Eastell R, Influence of baseline deformity definition on subsequent vertebral fracture risk in postmenopausl women. Osteo Int 2006, vol 17: Eastell R, Hannon RA, Cuzick J, Dowsett M, Clack, G, Adams JE, on behalf of the ATAC Trialists Group. Effect of an aromatase inhibitor on BMD and bone turnover markers: 2-year results of the Anastrozole, Tamoxifen, Alone or in Combination (ATAC) Trial ( ). J Bone Miner Res 2006, vol 21:8; Clowes JA, Peel NFA, Eastell R. Device-specific thresholds to diagnose osteoporosis at the proximal femur: an approach to interpreting peripheral bone measurements in clinical practice. Osteo Int 2006, vol 17:9; Kaptoge S, Armbrecht G, Felsenber D Eastell R..Reeve J. Whom to treat? The contribution of vertebral x-rays to risk-based algorithms for fracture prediction.

3 Results from the European Prospective Osteoporosis Study. Osteo Int 2006, vol 17:9; Stewart A, Felsenber D, Eastell R, Roux C, Gluer CC, Reid DM. Relationship between risk factors and QUS in a European Population: The OPUS study. Bone 2006, vol 39: Ali AM, Saleh M, Eastell R, Wigderowitz CA, Rigby AS, Yang L. Influence of bone quality on the strength of internal and external fixation of tibial plateau fractures. J Ortho Res 2006, Shetty N, Hamer AJ, Stockley I, Eastell R, Wilkinson JM. Clinical and radiological outcome of total hip replacement five years after pamidronate therapy. A trial extension. J Bone Joint Surg 2006, vol 88:10; Shetty N, Hamer AJ, Stockley I, Eastell R, Wilkinson JM. Precision of periprosthetic bone mineral density measurements using Holgic Windows versus DOS-based analysis software. J Clin Densitom 2006, vol 9:3;363-6 Rogers A. Clowes JA, Pereda CA, Eastell R. Different effects of raloxifene and estrogen on interleukin-1β and interleukin-1 receptor antagonist production using in vitro and ex vivo studies. Bone 2007, vol 40:1; Kaptoge S, Reid DM, Scheidt-Nave C, Eastell R,.Reeve J. Geographic and other determinants of BMD change in European men and women at the hip and spine. A population based study from the Network in Europe for Male Osteoporosis (NEMO). Bone 2007, vol 40:

4 Editorials, Reviews & Book Chapters 2005/6 Eastell R, Naylor KE, Cooper AM. Pathogenesis of transplantation bone disease: A unifying hypothesis. Bone Disease of Organ Transplantation. Eds J Compston and E Shane. Elsevier Academic Press 2005: Eastell R, Riggs BL. Vitamin D and Osteoporosis. Vitamin D, 2 nd edition. Eds D Feldman, J Wesley Pike, and F H Glorieux. Elsevier Academic Press 2005: Eastell R. Role of oestrogen in the regulation of bone turnover at the menarche. Journal of Endocrinology 2005; 185: Eastell R. Calcium requirements during treatment of osteoporosis in women. Preventive Nutrition, The comprehensive guide for health professionals. 3 rd edition.eds. A Bendich & R J Deckelbaum. Humana Press Inc 2005: Ferrar L, Jiang G, Adams J, Eastell R. Identification of vertebral fractures: An Update. Osteoporosis International 2005, vol 16:7; Eastell R, Delmas PD. How to interpret surrogate markers of efficacy in osteoporosis. Letter to the Editor. J Bone Miner Res 2005, vol 20:7; Author reply Eastell R, Hannon R. Long-term effects of aromatase inhibitors on bone. J Steroid Biochem Mol Biol 2005, vol 95(1-5): Clowes JA, Khosla S, Eastell R. Potential role of pancreatic and enteric hormones in regulating bone turnover. J Bone Miner Res 2005, vol 20:90; Eastell R. Management of bone health in postmenopausal women. Hormone Research2005, 64 (suppl 2):76-80 Eastell R. Osteoporosis. Medicine 2005 ; 33 :12 :61-65 Rogers A, Eastell R. Circulating osteoprotegerin and receptor activator for nuclear Factor kappab ligand : clinical utility in metabolic bone disease assessment. J Clin Endo Metab 2005, vol 90 :11;

5 Shetty N, Hamer AJ, Stockley I, Eastell R, Wilkinson JM. Effect of bisphosphonates on Periprosthetic bone mineral density after total joint arthroplasty. Letter to the Editor J Bone & Joint Surgery 2005, vol 87 :11 ; Clowes J, Eastell R. Corticosteroid-induced osteoporosis. Osteoporosis : State of the Art. Ed : N Arden. Remedica 2006, Eastell R. Pathogenesis of postmenopausal osteoporosis. Primer on the metabolic bone diseases and disorders of mineral metabolism. 6 th edition. Ed MJ Favus. American Society for Bone and Mineral Research 2006, Naylor KE, Eastell R. Measurement of biochemical markers of bone formation.dynamics of bone and cartilage metabolism. 2 nd edition. Eds MJ Seibel, SP Robins, JP Bilezikian. Academic Press 2006, Eastell R. Commentary - Does warfarin increase the risk of osteoporotic fracture? Nature Clinical Practice. Endocrinology & Metabolism 2006, vol 2 :9 ;485 Eastell R. Investigating suspected osteoporosis. Women s Health Medicine 2006, vol 3 :4 ; Eastell R. Treating Osteoporosis. Women s Health Medicine 2006, vol 3 :4, Amin S, Eastell R, Clowes JA. Risk factors for osteoporosis and fractures in men and women. Best Practice & Research Compendium Osteoporosis. Eds C Cooper & A D Woolf. Elsevier 2006, Hannon RA, Eastell R. Bone markers and current laboratory assays. Cancer Treat Rev 2006, suppl 1 :7-14 Eastell R. Breast cancer and the risk of osteoporotic fracture : A Pardox. J Clin Endo Metab 2007, vol 92 ;1 :42-43

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