The role of stabilizing and communicating symptoms given overlapping. communities in psychopathology networks
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1 The role of stabilizing and communicating symptoms given overlapping communities in psychopathology networks Tessa F. Blanken a,b,1,* Marie K. Deserno a,c,1 Jonas Dalege a Denny Borsboom a Peter Blanken d Gerard A. Kerkhof a,e Angélique O. J. Cramer f a Department of Psychology, University of Amsterdam, Nieuwe Achtergracht 129-B, 1018 WS Amsterdam, The Netherlands b Department of Sleep and Cognition, Netherlands Institute for Neuroscience, Meibergdreef 47, 1105 BA Amsterdam, The Netherlands c Dr. Leo Kannerhuis and REACH-AUT, Houtsniplaan 1a, 6865 XZ Doorwerth, The Netherlands d Parnassia Addiction Research Centre (PARC, Brijder Addiction Treatment), Zoutkeetsingel 40, 2512 HN The Hague, The Netherlands e Sleep Disorders Center MCH, Lijnbaan 32, 2512 VA The Hague, The Netherlands f Department of Methodology and Statistics, Tilburg School of Social and Behavioral Sciences, Tilburg University, Warandelaan 2, 5037 AB Tilburg, The Netherlands 1 These authors contributed equally to this work.
2 Supplementary Material Appendix A. Overview of the SCL-90 items and their associated communities and dimensions. Supplementary Methods. Network Stability
3 Appendix A. Overview of the SCL-90 items and their associated communities and dimensions SCL-90 items and dimensions communities #1 #2 #3 #4 #5 #6 #7 #8 #9 #10 #11 #12 #13 #14 #15 #16 #17 #18 3 Repeated unpleasant thoughts that won't leave your mind 5 Loss of sexual interest or pleasure * 14 Feeling low in energy or slowed down 15 Thoughts of ending your life 19 Poor appetite 20 Crying easily Depression 22 Feeling of being trapped or caught 26 Blaming yourself for things 29 Feeling lonely 30 Feeling blue 31 Worrying too much about things 32 Feeling no interest in things 51 Your mind going blank 54 Feeling hopeless about the future 59 Thoughts of death or dying 79 Feelings of worthlessness 2 Nervousness or shakiness inside 17 Trembling 23 Suddenly scared for no reason 33 Feeling fearful Anxiety 39 Heart pounding 57 Feeling tensed or keyed up 72 Spells of terror or panic 78 Feeling so restless you couldn't sit still * 80 The feeling that something bad is going to happen to you 86 Thoughts and images of a frightening nature 13 Feeling afraid in open spaces or streets Agoraphobia 25 Feeling afraid to get out of your house alone 47 Feeling afraid to travel on buses, subways or trains Having to avoid certain things, places, or activities because they 50 frighten you 70 Feeling uneasy in crowds such as shopping or at movies 75 Feeling nervous when you are left alone 82 Feeling afraid you will faint in public
4 SCL-90 items and dimensions communities #1 #2 #3 #4 #5 #6 #7 #8 #9 #10 #11 #12 #13 #14 #15 #16 #17 #18 Sleep difficulty Somatization Interpersonal sensitivity-mistrust 44 Trouble falling asleep 64 Awakening early in the morning 66 Sleep that is restless or disturbed 1 Headaches 4 Faintness or dizziness 12 Pain in heart or chest 27 Pains in lower back 40 Nausea or upset stomach 42 Soreness of muscles 48 Trouble getting your breath 49 Hot or cold spells 52 Numbness or tingling in parts of your body 53 A lumb in your throat 56 Feeling week in parts of your body 58 Heavy feelings in your arms or legs 6 Feeling critical of others 7 The idea that someone else can control your thoughts 8 Feeling others are to blame for most of your troubles 18 Feeling that most people cannot be trusted 21 Feeling shy and uneasy with the opposite sex 34 Your feelings being easily hurt 35 Other people being aware of your private thoughts 36 Feeling others do not understand you or are unsympathetic 37 Feeling that people are unfriendly or dislike you 41 Feeling inferior to others 43 Feeling that you are watched or talked about by others 61 Feeling uneasy when people are watching or talking about you 68 Having ideas or beliefs that others do not share 69 Feeling very self-conscious with others 73 Feeling uncomfortable about eating or drinking in public 76 Others not giving you proper credit for achievements 83 Feeling that people will take advantage of you if you let them 88 Never feeling close to another person
5 SCL-90 items and dimensions communities 11 Feeling easily annoyed or irritated #1 #2 #3 #4 #5 #6 #7 #8 #9 #10 #11 #12 #13 #14 #15 #16 #17 #18 Acting-out hostility 24 Temper outbursts that you could not control 63 Having urges to beat, injure or harm someone 67 Having urges to break or smash things 74 Getting into frequent arguments 81 Shouting or throwing things 9 Trouble remembering things Cognitive-performance deficits 10 Worried about sloppiness or carelessness 28 Feeling blocked in getting things done 38 Having to do things very slowly to insure correctness 45 Having to double-check what you do 46 Difficulty making decisions 55 Trouble concentrating Having to repeat the same actions, such as touching, counting, 65 washing 71 Feeling everything is an effort 16 Hearing voices that other people don't hear Unscaled SCL-90 items 60 Overeating 62 Having thoughts that are not your own 77 Feeling alone even when you are with people 84 Having thoughts about sex that bother you a lot 85 The idea that you should be punished for your sins 87 The idea that something serious is wrong with your body 89 Feelings of guilt 90 The idea that something is wrong with your mind Denotes symptoms belonging to a community (i.e., problem area) Denotes 'stabilizing' symptoms within a community (i.e., within a problem area) Denotes 'communicating' symptoms between communities (i.e., between problem areas) * Denotes symptoms that are not associated with any community (#5 Loss of sexual interest or pleasure - depression, and #78 Feeling so restless you couldn't sit still - anxiety)
6 Supplementary Methods. Network Stability edge Figure S1. Bootstrapped edge weights. The red line depicts point estimates of the edge weights in the reported network, the grey bars represent 95% confidence intervals. Bootstrapping results indicated good accuracy of the estimated network parameters, see Figure S1. In addition, we calculated the correlation stability coefficient (CS), which represents the maximum proportion of participants that can be dropped while maintaining results that correlate at least 0.7 with the results obtained on the complete sample. We specifically focused on the stability of the strength and number of connections a node has (i.e., degree centrality) as this is most relevant for our community detection analyses. With a CS of 0.52 the stability exceeded the proposed cut-off of 0.5, suggesting good stability.
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