OPAT Community and Outcomes: The OPAT Service Directory and National Outcomes Registry

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2 OPAT Community and Outcomes: The OPAT Service Directory and National Outcomes Registry

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7 For enquiries/support:

8 Service Directory in Action! Can BSAC sort out daily antibiotics? GP R

9 OPAT Community and Outcomes: The OPAT Service Directory and National Outcomes Registry

10 The National OPAT Outcomes Registry Provides the most comprehensive overview of OPAT service provision across the UK & Ireland Free of charge Accessible Easy to use

11 Enter data Value of Service NORS Bench mark Regional or National

12 NORS Data Support Service Expansion Improve stewardship Shared Learning Improve patient outcomes

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15 Add, edit & review data

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17 Data Comparisons Number of patient episodes Number of treatment days saved Antimicrobial agents used Infection Outcomes: Cured, Improved, Failed OPAT Outcomes: Success, Partial, Failed, Intermediate

18 NORS Reports Flexible Build Excel download Large amounts

19 Reports Region Service Type PIDS Adverse Agents Treatment days saved Patient episodes Event Reaction Up to 3 drugs IV +/- oral

20 PID Report

21 Number of Treatment Days Saved by PID (2017) Actinomycosis Aspergillosis Bacterial meningitis Bursitis 4668 Cellulitis Cholangitis 1682 Diabetic foot infection (no Discitis/vertebral osteomyelitis - Empyema Endocarditis Hepatic abscess Intraabdominal abscess Lyme Lymphadenitis Malignant otitis externa Orbital cellulitis Osteomyelitis - non surgical Other Pelvic Abcess Pneumonia - Community 3052 Prosthetic joint - knee Prosthetic joint- hip Pyrexial of unknown origin Salmonella Sinusitis Syphilis Tonsillitis Urinary tract infection Viral infection Wound Infection - post surgical

22 Number of Patient Episodes by PID (2017): A-M list Actinomycosis Appendicitis Aspergillosis Bacteraemia / blood stream infection/ Bacterial meningitis Bronchiectasis Bursitis Candidiasis Cellulitis Cerebral abscess Cholangitis Cystic fibrosis - infective episode Diabetic foot infection (no osteomyelitis) Discitis/vertebral osteomyelitis - Discitis/vertebral osteomyelitis - no Diabetic foot infection (no osteomyelitis) Empyema Encephalitis Endocarditis Epidural abscess Hepatic abscess Infected pacing box Intraabdominal abscess Line related infection - systemic Lyme Lyme (Neuro) Lymphadenitis MAI (Non-tuberculous mycobacteria) Malignant otitis externa

23 Number of Patient Episodes by PID (2017): M-Z list Mastoiditis Orbital cellulitis Osteomyelitis - diabetic foot Osteomyelitis - non surgical Osteomyelitis - surgically related Other Otitis media Pelvic Abcess Periorbital cellulitis Pneumonia - Community Acquired Pneumonia - Hospital Acquired Prosthetic joint - knee Prosthetic joint - other Prosthetic joint- hip Psoas Abscess Pyrexial of unknown origin Respiratory tract infection - other Salmonella Septic arthritis Sinusitis Skin and soft tissue infection Syphilis Syphilis (Neuro) Tonsillitis Tuberculosis Urinary tract infection Vascular graft infection Viral infection VP Shunt Infection Wound Infection - post surgical

24 OPAT & Infection Outcomes (2017) Success Partial success Indeterminate Failure Cure Improved Failure OPAT Outcome Infection Outcome

25 Adverse Reactions Report

26 Adverse Reactions Reported (2017) Blood dyscrasia 0 C. Diff Diarrhoea (antibiotic induced) Hepatitis Other Rash Allergy to Dressing Infection Line migration Line occlusion Other Thrombus Drug Line

27 Antimicrobial Agents Report

28 Top 10 Antimicrobial Agents (2017) Total Treatment Days Saved Total Episodes Ceftriaxone Ceftazidime Teicoplanin Meropenem Ertapenem Daptomycin Pip/Taz Ciprofloxacin Flucloxacillin Rifampicin

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30 Contributing Services (2017)

31 Image from: Acknowledgments

32 OPAT Services contributing 2017 data Aberdeen Royal Infirmary Leeds (Adult, Teaching, Hospital site) Airedale NHS Foundation Trust (Adult, Teaching, Hospital site) Birmingham Heartlands Hospital Leeds (Adult, Specialist, Hospital site) Buckinghamshire Healthcare OPAT service Leeds (Adult, Teaching, Hospital site) Calderdale Royal Hospital (Adult, Specialist, Primary Care) County Durham and Darlington NHS Foundation Trust (Adult, Specialist, Hospital site) Great Western Hospital, Swindon (Adult, Teaching, Hospital site) Guy's and St Thomas' Hospital NHS Trust (Adult, Teaching, Hospital site) Harefield Hospital OPAT (Adult, Specialist, Hospital site) Imperial College Healthcare NHS Trust Adult OPAT Service (Adult, Teaching, Hospital site) Kettering Diabetic Foot OPAT pilot service (Adult, Specialist, Hospital site) Leeds (Adult, Teaching, Hospital site) Locala IV Team (Adult, Specialist, Primary Care) Nottingham University Hospitals NHS Trust (Adult, Teaching, Hospital site) OPAT Greater Glasgow & Clyde (Adult, Teaching, Hospital site) Portsmouth Out of Hospital Services (Adult, Teaching, Hospital site) Raigmore Hospital (Adult, Teaching, Hospital site) Royal Liverpool and Broadgreen University Hospitals Trust (Adult, Teaching, Hospital site) Royal National Orthopaedic Hospital (Adult, Specialist, Hospital site) Sheffield Children's Hospital (Paediatric Hospital site) St Mary's Hospital, Newport, Isle of Wight (Adult, Specialist, Hospital site) The James Cook University Hospital, Middlesbrough (Adult, Teaching, Hospital site) University College Hospital (Adult, Teaching, Hospital site) Wirral OPAT Service, Arrowe Park Hospital (Adult, Teaching, Hospital site) Wythenshawe Hospital, Manchester University NHS Foundation Trust (Adult, Teaching, Hospital site)

33 NORS Development & Testing Group Mark Gilchrist: Imperial College Healthcare NHS Trust & BSAC OPAT Co-chair Carolyn Hemsley: Guy s & St Thomas NHS Foundation Trust Matthew Laundy: St George s University Hospitals NHS Trust Sarah Logan: University College Hospital Sanjay Patel: Southampton Children s Hospital Andrew Seaton: NHS Greater Glasgow and Clyde & BSAC OPAT co-chair Sue Snape: Nottingham University Hospitals NHS Trust Claire Vallance: OPAT Greater Glasgow & Clyde

34 Early Adopters Airedale NHS Foundation Trust - Fiona Throp Buckinghamshire Healthcare Trust - Marie Woodley County Durham and Darlington NHS Foundation Trust - Alex Maurer Greater Glasgow & Clyde - Claire Vallance Guy's and St Thomas' NHS Foundation Trust - Carolyn Hemsley Heart of England NHS Foundation Trust - Jo Spicer Isle of Wight NHS Trust - Mel Stevens & Amanda Wilson Leeds Teaching Hospitals NHS Trust - Jane Minton Manchester University Foundation Trust - Elizabeth Wilson Portsmouth Hospitals NHS Trust - Sydnee Williams Royal Liverpool and Broadgreen University Hospitals Trust - Ian Byrom South Tees Hospitals NHS Foundation Trust - John Williams University College London Hospitals Trust Sarah Logan Wirral University Teaching Hospital NHS Foundation Trust - Sharon Bamber

35 Man can accomplish anything when he realises that he is a part of something bigger. A team of people who share that conviction can change the world.

36 Register for the BSAC Newsletter Michael Corley, Policy and Public Affairs Officer, BSAC

37 All Antimicrobial Agents Administered in 2017 Treatment Days Saved = 57,728 Episodes = 4, Aciclovir Amikacin + Ethambutol + Amoxicillin + Daptomycin Amphotericin Aztreonam + Tobramycin Total Treatment Days Saved Total Episodes Ceftazidime Ceftazidime + Metronidazole Ceftriaxone Ceftriaxone + Ciprofloxacin + Ceftriaxone + Daptomycin Ceftriaxone + Gentamicin Ceftriaxone + Metronidazole Ceftriaxone + Teicoplanin Ciprofloxacin + Colistin Ciprofloxacin + Ertapenem + Ciprofloxacin + Linezolid + Ciprofloxacin + Teicoplanin Clindamycin Colistin Daptomycin Daptomycin + Levofloxacin Doxycycline Ertapenem + Fluconazole + Ertapenem + Linezolid + Flucloxacillin Fluconazole Fusidic Acid Imipenem Levofloxacin Linezolid + Other - Free text Meropenem Other - Free text Prothionamide Rifampicin + Teicoplanin Tigcycline Trimethoprim

38 Table of Top 10 Antimicrobial Agents Administered in 2017 Agent Treatment Days Saved Patient Episodes Ceftriaxone Ceftazidime Teicoplanin Meropenem Ertapenem Daptomycin Piperacillin/ Tazobactam Ciprofloxacin Flucloxacillin Rifampicin

39 Scotland Services Contributing 2017 Data Service Treatment Days Saved Episodes Aberdeen Royal Infirmary OPAT Greater Glasgow & Clyde Raigmore Hospital TOTAL

40 England Services Contributing 2017 Data SERVICE NAME Aberdeen Royal Infirmary Airedale NHS Foundation Trust, Community IV pathway Birmingham Heartlands Hospital Buckinghamshire Healthcare OPAT service Calderdale Royal Hospital County Durham and Darlington NHS Foundation Trust OPAT Service Great Western Hospital, Swindon Guy's and St Thomas' Hospital NHS Trust Harefield Hospital OPAT Imperial College Healthcare NHS Trust Adult OPAT Service Kettering Diabetic Foot OPAT pilot service Leeds Locala IV Team Nottingham University Hospitals NHS Trust OPAT Greater Glasgow & Clyde Portsmouth Out of Hospital Services Raigmore Hospital Royal Liverpool and Broadgreen University Total Treatment Days Saved Episodes Count

OPAT DATA MANAGEMENT: AN OVERVIEW OF NORS & THE OPAT SERVICE DIRECTORY. BSAC OPAT REGIONAL WORKSHOP London 14 May 2018

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