Pulmonary langerhans cell histiocytosis: Two cases with varied radiologic findings

Size: px
Start display at page:

Download "Pulmonary langerhans cell histiocytosis: Two cases with varied radiologic findings"

Transcription

1 CASE REPORT Est J Med 21(1): 45-49, 2016 Pulmonry lngerhns cell histiocytosis: Two cses with vried rdiologic findings Huly Guntr 1,*, Alpsln Yvuz 2, Bunymin Sertogullrindn 1, Selmi Ekin 1, Selvi Asker 1, Fut Syır 3, Irfn Byrm 4 1Deprtment of Pulmonry nd Criticl Cre, Yuzuncu Yil University Medicl Fculty, Vn, Turkey 2Deprtment of Rdiology, Yuzuncu Yil University, Medicl Fculty, Vn Turkey 3Deprtment of Pulmonry Surgery, Yuzuncu Yil University Medicl Fculty, Vn Turkey 4Deprtment of Pthology, Yuzuncu Yil University Medicl Fculty, Vn Turkey ABSTRACT Pulmonry Lngerhns Cell Histiocytosis (PLCH) is n idiopthic interstitil lung disese with Lngerhns cell infiltrtion in the lung. PLCH X hs non-spesific symptoms, nd most ptients hve smoking history. A comintion of stellte nodules, reticulr nd nodulr opcities, upper zone cysts or honeycoming, preservtion of lung volume nd costophrenic ngle spring re highly specific for PLCH. To contriute to the literture, two cses re presented. First cse is 30 yers old mn with 10 pck/yers smoking history ws dmitted with cough nd persevering interstitil opcities. Second cse is 34 yers old mn with 15 pck/yers smoking history ws dmitted with persistnt cough. On thorx CT the first cse hd reticulonodulr opcities t the perifery of the upper nd middle zones, second cse hd multiple prenchyml cystic nodulr lesions. Open lung iopsy performed, immunohistochemicl exmintion CD1, CD68, S100 detecting ntigenpositive nd histologiclly nd rdiologiclly confirmed dignosed of PLCH. Key Words: Pulmonry Lngerhns cell histiocytosis, rdiology, histology Introduction Pulmonry Lngerhns Cell Histiocytosis (PLCH) is rre form of interstitil lung diseses tht primrily ffects young dults (1-5). The certin incidence nd prevlence re unknown. No occuptionl or geogrphic predisposition hs een reported, ut mjority of the ffected popultion hve history of ongoing or pst smoking. The Lngerhns cell is the pthologic cell type of PLCH. Lngerhns cells lso demonstrte positive immunohistochemicl stining for S100 protein nd hve strong presence of CD1 ntigen (CD1) on the cell surfce. Ptients with PLCH re mostly determined y sole or comintion of severl ltered presenttions such s; incidentlly detected findings on chest rdiogrphs including spontneous pneumothorx nd/or with respirtory or constitutionl symptoms (6,7). High resolution computed tomogrphy (HRCT) of the chest cn provide significnt dt to led the dignosis. A comintion of the fetures such s stellte nodules lung volume nd costophrenic ngle spring re highly specific for PLCH (8,9). Becuse of the rrity; we reported the vried rdiologicl fetures of two cses with histologiclly nd rdiologiclly confirmed dignosed of PLCH. Cse report Cse 1: A 30 yers old mn referred with two month history of dyspne, cough, sputum nd night swets. Before his dmission, he hd n ntiiotherpy in nother epicenter, his complints hve regressed. He ws referred to our hospitl ecuse of the persevering normlities detected on chest rdiogrphs. On his initil dmission; physicl exmintion nd routine hemtology prmeters including ESR were within norml rnges (ESR ws 7 mm t the end of first hour). Sputum cultures including for tuerculosis were negtive. Blood gses nd pulmonry function tests were norml. In nmnesis, he hd 10 pck/yer smoking history. The chest X-ry reveled reticulonodulr opcities t the perifery of the upper nd middle zones. In thorx computed tomogrphy (CT) exmintion; pulmonry prenchyml nodules with rnge of 1-5 mm in dimeter were detected, lesions were mostly with centriloulr distriution (rrows), ut few were locted t supleurl region (rrow hed). Mgnified investigtion of the pulmonry prenchym on chest CT reveled centrl hypo-dense components leding cvittion (Imge 1,). Open lung iopsy performed to the ptient, immunohistochemicl exmintion This report ws provided s cse of council in TÜSAD 2014 ntionl rething congress *Corresponding Author: Dr Hüly Güntr, Deprtment of Pulmonry nd Criticl Cre, Yuzuncu Yil University Medicl Fculty, Vn, Turkey, Phone: +90 (432) , Moil Phone: +90 (506) , E-mil: hulyguntr@hotmil.com Received: , Accepted:

2 CD1, CD68, S100 detecting ntigen-positive nd lngerhns cell histiocytosis dignosed (Figure 1,,c). Fluorodeoxyglucose-PET (FDG-PET) ws performed the ptient for determining the systemic involvement, FDG PET imging ws negtive. Smoking cesstion ws recommended, he stopped smoking nd still in follow up. Imge 1. Chest CT imge from 27-yer-old smoker mle with iopsy-proven Pulmonry Lngerhns cell histiocytosis demonstrting multiple pulmonry nodules which mostly pronounced erly in the disese. ) Nodules were 1-5 mm in dimeter, mostly with centriloulr distriution (rrows), ut few were locted t supleurl region (rrow hed). ) Mgnified exmintion on chest CT reveled centrl hypo-dense components leding cvittion. c Fig 1. lrge clusters of cells tht re comptile with eosinophilic cytoplsm infiltrting Lngerhns cells (H & E x10). ) memrnous stining of CD1, Lngerhns cells (immunohistochemicl exmintion, x20). c) S100 proteins in the nucler nd cytoplsmic stining, Lngerhns cells (immunohistochemicl exmintion, x20). 46

3 Cse 2: A 34 yers old mn, who ws n employee s technicin of n operting room, ws referred with two month history of cough nd incresed sensitivity to odors. Physicl exmintion ws norml. He hd 15 pck/yer history of smoking. After non-specific ntiiotherpy, HRCT ws performed ecuse of the progression in cough. Chest CT imge reveled multiple prenchyml cystic nodulr lesions rnging 5-20 mm in dimeter, mostly with the wll-thickness of few millimeters. Vrile shpes with loulted contours were detected s the result of the confluence of 2 or more lesions. Coronl reformt CT imge demonstrted the mid nd upper zone predilection (Imge 2,). Blood gses nd pulmonry function tests were norml. He ws dignosed s lngerhns cell histiocytosis ecuse of typiclly HRCT findings, smoking cesstion ws recommended, he left smoking nd still in follow up s symptomtic. Discussion The histiocytic disorders re rre conditions chrcterized y norml infiltrtion of specific orgns y cells reproduced from monocyte/mcrophge or dendritic cell origin. Lngerhns cell histiocytosis (LCH) is specific type of histocytic syndromes which is chrcterized y infiltrtion of the tissues with Lngerhns cells (10). LCH my ffect n isolted orgn or my ct s multisystemic disese (formerly termed s Hnd- Shuller-Christin or Letterer-Siwe disese) (11). In our cses, pulmonry involvement ptterns were demonstrted solely. The signs nd symptoms of PLCH re nonspecific nd should prompt considertion of superimposed infection such s Aspergillus or tumor (12, 13). Nonproductive cough, dyspne nd pleuritic chest pin re the most common symptoms (1,5,14). Cough ws the most frequent symptom in our cses. The pulmonry involvement y the disese predomintes in the mid to upper zones of the lung nd spres the costophrenic ngle which is in contrst with the typicl lower zone involvement of idiopthic pulmonry firosis (8,15). Lesions frequently extend widely into the prenchym of the lung surrounding the ronchovsculr structures, producing the soclled stellte lesions tht re chrcteristic of this disorder. Interstitil firosis nd smll cyst formtion occur with dvncing disese; the mechnism for cyst formtion is unknown (7). Reticulonodulr infiltrtions re dominnt findings in chest CT in erly stge wheres cystic lesions nd emphysem re more predominnt in dvnced stge. In the first cse of our report; reticulonodulr infiltrtes were predominnt, cvitted nodules locted t the perironchil nd centriloulr region were determined. These findings supported tht the disese ws t its erly stge. However; in the second cse, findings including diffuse cyst formtions locted t the upper nd middle zones of the pulmonry prenchym indicted tht the disese ws on n dvnced stge especilly when compred with the first cse. The clinicl signs nd symptoms of PLCH re mostly my not e sufficient to distinguish itself from other non-specific pulmonry diseses. HRCT of the chest cn provide n ccurte finl dignosis if is demonstrting well-descried CT findings of the issue, s prticulrly in the second cse. Imge 2. Chest CT imge from 33-yer-old mle with iopsy-proven Pulmonry Lngerhns cell histiocytosis. ) Cysts were 5-20 mm in dimeter, mostly with the wll-thickness of few millimetres. Vrile shpes were seen s the result of the confluence of 2 or more cysts. ) Coronl reformt CT imge demonstrted the mid nd upper zone predilection. 47

4 Pulmonry function tests re norml out 20% of ptients. Restrictive pttern is commonly seen in erlier stges, while ostructive pttern ecomes dominnt in dvnced stges (12,16). In our presenttion, two cses hd norml pulmonry function tests. FDG-PET CT scns my show incresed uptke in PLCH, especilly t erly stge in the course of disese. Krjicek et l. (17) evluted series of 11 ptients with PLCH; five of the ptients hd norml FDG uptke in their lungs. The ptients with FDG-PET positivity were more likely to hve nodulr pttern, suggesting erlier disese; those with negtive FDG-PET scns were more likely to hve cystic pttern nd less nodules, suggesting n dvnced disese. In the first cse of our report; FDG-PET ws negtive which could e explined y the existence of the smll sized nodules in pulmonry prenchym, ecuse previous reports reveled tht FDG ctivity in PET CT cn e negtive for the nodules with sizes less thn 1 cm (18,19). Surgicl pproches including Video Assisted Thorcic Surgery or open lung iopsies my e involved to provide definite dignosis of PLCH; thus, demonstrtion of the specific histopthologicl fetures cn e otined (20,21). Lngerhns cells lso demonstrte positive immunohistochemicl stining for S100 protein nd hve strong presence of CD1 ntigen (CD1) on the cell surfce. In the first cse open lung iopsy specimens showed CD1, CD68, S100 detecting ntigen-positive nd lngerhns cell histiocytosis dignosed. There is no widely ccepted definite tretment guideline protocol for PLCH mngement in recent literture except few recommendtions tht were reported regrding to tretment of dult ptients with PLCH The most effective component of the PLCH tretment is indicted s smoking cesstion. It ws reported tht the smoking cesstion my solely prevent the progression of the disese so, it should e strongly encourged (14,21). In conclusion, PLCH is n extremely rre enign disese. The ptients could referred with different cliniclly nd rdiologiclly findings. References 1. Tzi A, Soler P, Hnce AJ. Adult pulmonry Lngerhns' cell histiocytosis. Thorx 2000; 55: Vssllo R, Ryu JH, Coly TV, Hrtmn T, Limper AH. Pulmonry Lngerhns'-cell histiocytosis. N Engl J Med 2000; 342: Vssllo R, Ryu JH. Pulmonry Lngerhns' cell histiocytosis. Clin Chest Med 2004; 25: Sundr KM, Gosselin MV, Chung HL, Chill BC. Pulmonry Lngerhns cell histiocytosis: emerging concepts in pthoiology, rdiology, nd clinicl evolution of disese. Chest 2003; 123: Tzi A. Adult pulmonry Lngerhns' cell histiocytosis. Eur Respir J 2006; 27: Bsset F, Corrin B, Spencer H, et l. Pulmonry histiocytosis X. Am Rev Respir Dis 1978; 118: Vssllo R, Limper AH. Pulmonry Lngerhns cell histiocytosis. Interstitil Lung Disese, 4th ed, King TE Jr, Schwrz MI (Eds), B.C. Decker, Hmilton, ON, Cnd p Kulwiec EL, Lynch DA, Aguyo SM, Schwrz MI, King TE Jr. Imging of pulmonry histiocytosis X. Rdiogrphics 1992; 12: Lcronique J, Roth C, Bttesti JP, Bsset F, Chretien J. Chest rdiologicl fetures of pulmonry histiocytosis X: report sed on 50 dult cses. Thorx 1982; 37: Fvr BE, Feller AC, Puli M, et l. Contemporry clssifiction of histiocytic disorders. The WHO Committee On Histiocytic/Reticulum Cell Prolifertions. Reclssifiction Working Group of the Histiocyte Society. Med Peditr Oncol 1997; 29: Komp DM. Historicl perspectives of Lngerhns cell histiocytosis. Hemtol Oncol Clin North Am1987; 1: Crusmn RS, Jennings CA, Tuder RM, et l. Pulmonry histiocytosis X: pulmonry function nd exercise pthophysiology. Am J Respir Crit Cre Med 1996; 153: Knight RK. Hemoptysis in eosinophilic grnulom. Br J Dis Chest 1979; 73: Cminti A, Hrri S. Smoking-relted interstitil pneumonis nd pulmonry Lngerhns cell histiocytosis. Proc Am Thorc Soc 2006; 3: Kim HJ, Lee KS, Johkoh T, et l. Pulmonry Lngerhns cell histiocytosis in dults: highresolution CT-pthology comprisons nd evolutionl chnges t CT. Eur Rdiol 2011; 21: Vssllo R, Ryu JH, Schroeder DR, Decker PA, Limper AH. Clinicl outcomes of pulmonry Lngerhns -cell histiocytosis in dults. N Engl J Med 2002; 346: Krjicek BJ, Ryu JH, Hrtmn TE, Lowe VJ, Vssllo R. Anorml fluorodeoxyglucose PET in pulmonry Lngerhns cell histiocytosis. Chest 2009; 135: Higshi K, Ued Y, Seki H, et l. Fluorine-18-FDG PET imging is negtive in ronchiololveolr lung crcinom. J Nucl Med 1998;39:

5 19. Ersmus JJ, McAdms HP, Ptz EF, et l. Evlution of primry pulmonry crcinoid tumors using FDG-PET AJR 1998; 170: Suri HS, Yi ES, Nowkowski GS, Vssllo R. Pulmonry ln-gerhns cell histiocytosis. Orphnet J Rre Dis 2012; 7: Juvet SC, Hwng D, Downey GP. Rre lung diseses III: pul-monry Lngerhns' cell histiocytosis. Cn Respir J 2010; 17:

A Rare Manifestation of Solitary Primary Bone Lymphoma of the Finger: a Case Report

A Rare Manifestation of Solitary Primary Bone Lymphoma of the Finger: a Case Report pissn 2384-1095 eissn 2384-1109 imri 2018;22:240-244 A Rre Mnifesttion of Solitry Primry Bone Lymphom of the Finger: Cse Report Jeong A Yeom 2, You Seon Song 1 *, In Sook Lee 1, Kyung Un Choi 3, Jeung

More information

Chapter. Imaging of SARS in North America. Introduction. Clinical Manifestations of SARS in North America

Chapter. Imaging of SARS in North America. Introduction. Clinical Manifestations of SARS in North America content Chpter 13 Nestor L. Müller, Hrry Shulmn Introduction Clinicl Mnifesttions of SARS in North Americ Rdiogrphic Mnifesttions of SARS in North Americ High Resolution CT Findings of SARS in North Americ

More information

Thallium-201 chloride scintigraphy in soft tissue tumors

Thallium-201 chloride scintigraphy in soft tissue tumors 136 ORIGINAL Thllium-201 chloride scintigrphy in soft tissue tumors Hideki Otsuk, Kori Terzw, Nomi Morit, Yoichi Otomi, Shoichiro Tko, Seiji Iwmoto, Kyosuke Oski, Msfumi Hrd, nd Hiromu Nishitni Deprtment

More information

High-Resolution Computed Tomographic Evaluation of Pulmonary Diseases in Human Immunodeficiency Virus Positive Patients: A Study of 30 Cases

High-Resolution Computed Tomographic Evaluation of Pulmonary Diseases in Human Immunodeficiency Virus Positive Patients: A Study of 30 Cases Originl Article DOI: 10.17354/ijss/2015/359 High-Resolution Computed Tomogrphic Evlution of Pulmonry Diseses in Humn Immunodeficiency Virus Positive Ptients: A Study of 30 Cses Mnoj Hzrik 1, Nnit Dek 2,

More information

Identical twins with borderline lepromatous leprosy mimicking extensive alopecia areata: A rare presentation

Identical twins with borderline lepromatous leprosy mimicking extensive alopecia areata: A rare presentation Lepr Rev (2018) 89, 301 305 CASE REPORT Identicl twins with orderline lepromtous leprosy mimicking extensive lopeci ret: A rre presenttion RUBINA JASSI*, KRISHNA DEB BURMAN**, BHAVYA SWARNKAR** & RADHIKA

More information

Case Report Surgical Resection of a Leiomyosarcoma of the Inferior Vena Cava Mimicking Hepatic Tumor

Case Report Surgical Resection of a Leiomyosarcoma of the Inferior Vena Cava Mimicking Hepatic Tumor Cse Reports in Medicine Volume 2013, Article ID 235698, 5 pges http://dx.doi.org/10.1155/2013/235698 Cse Report Surgicl Resection of Leiomyosrcom of the Inferior Ven Cv Mimicking Heptic Tumor Junji Ued,

More information

Successful Diagnosis of a Thymoma by Endobronchial Ultrasound-guided Transbronchial Needle Aspiration: A Report of Two Cases

Successful Diagnosis of a Thymoma by Endobronchial Ultrasound-guided Transbronchial Needle Aspiration: A Report of Two Cases CASE REPORT Successful Dignosis of Thymom y Endoronchil Ultrsound-guided Trnsronchil Needle Aspirtion: A Report of Two Cses Ysushi Yoshid 1, Msto Singyoji 1, Hironori Ashinum 1, Meiji Itkur 1, Toshihiko

More information

Seeding Metastasis of Chromophobe Renal Cell Carcinoma after Robot-Assisted Laparoscopic Partial Nephrectomy

Seeding Metastasis of Chromophobe Renal Cell Carcinoma after Robot-Assisted Laparoscopic Partial Nephrectomy pissn 2384-1095 eissn 2384-1109 imri 2017;21:119-124 https://doi.org/10.13104/imri.2017.21.2.119 Seeding Metstsis of Chromophoe Renl Cell Crcinom fter Root-Assisted Lproscopic Prtil Nephrectomy Knghun

More information

Prosthetic Valve Dysfunction 35 Years after Mitral Valve Replacement with a Starr-Edwards Caged-disc Valve

Prosthetic Valve Dysfunction 35 Years after Mitral Valve Replacement with a Starr-Edwards Caged-disc Valve CASE REPORT Prosthetic Vlve Dysfunction 35 Yers fter Mitrl Vlve Replcement with Strr-Edwrds Cged-disc Vlve Tetsuro Yokokw 1, Tkhiro Ohr 1, Seiji Tkshio 1, Mri Skmoto 1,YukoWd 1, Kenji Nkmur 1, Hiroyuki

More information

PNEUMOVAX 23 is recommended by the CDC for all your appropriate adult patients at increased risk for pneumococcal disease 1,2 :

PNEUMOVAX 23 is recommended by the CDC for all your appropriate adult patients at increased risk for pneumococcal disease 1,2 : PNEUMOVAX 23 is recommended y the CDC for ll your pproprite dult ptients t incresed risk for pneumococcl disese 1,2 : Adults ged

More information

Tracheobronchitis with Dyspnea in a Patient with Ulcerative Colitis

Tracheobronchitis with Dyspnea in a Patient with Ulcerative Colitis CASE REPORT Trcheoronchitis with Dyspne in Ptient with Ulcertive Colitis Msy Hiyoshi 1,2, Kzushige Kwi 2, Mihoko Shiuy 3, Tsuyoshi Ozw 2, Junko Kishikw 2, Tkko Nirei 2, Toshiki Tnk 2, Junichiro Tnk 2,

More information

Anus,Rectum and Colon

Anus,Rectum and Colon JOURNAL OF THE Anus,Rectum nd Colon http://journl-rc.jp CASE REPORT Anl Cnl Dupliction Associted with Prescrl Cyst in n Adult Tkyuki Toyong 1), Hiromitsu Mtsud 1), Ryuichi Miu 1), Yohei Toming 1), Keiji

More information

Fluoroscopy Guided Percutaneous Transpedicular Biopsy for Thoracic and Lumbar Vertebral Body Lesion: Technique and Safety in 23 Consecutive Cases.

Fluoroscopy Guided Percutaneous Transpedicular Biopsy for Thoracic and Lumbar Vertebral Body Lesion: Technique and Safety in 23 Consecutive Cases. Fluoroscopy Guided Percutneous Trnspediculr Biopsy for Thorcic nd Lumr Verterl Body Lesion: Technique nd Sfety in 23 Consecutive Cses. Shresth D, Shresth R, Dhoju D ABSTRACT Bckground Deprtment of Orthopedic

More information

Colonoscopic decompression of childhood sigmoid and cecal volvulus

Colonoscopic decompression of childhood sigmoid and cecal volvulus CASE REPORT Colonoscopic decompression of childhood sigmoid nd cecl volvulus Irj Shhrmin 1, Ali Bzi 1,2, Dnil Edti 3, Krim Rostmi 3, Mojt Delrmns 1,2 1 Peditric Digestive nd Heptic Reserch Center, Zol

More information

Fundamentals of Spine MRI and Essential Protocols

Fundamentals of Spine MRI and Essential Protocols Fundmentls of Spine MRI nd Essentil Protocols A. C. Dougls-Akinwnde, MD Octoer 13, 2009 Fundmentls of Spine MRI Lerning Ojectives: 1. List the essentil sequences for Spine MRI exmintion 2. Discuss the

More information

BENIGN ulceration along the greater curvature of the pars media of the

BENIGN ulceration along the greater curvature of the pars media of the BENIGN ULCERS OF THE GREATER CURVATURE OF THE STOMACH Report of Two Cses CHARLES H. BROWN, M.D. Deprtment of Gstroenterology nd ANTHONY D. INTRIERE, M.D.* BENIGN ulcertion long the greter curvture of the

More information

An autopsy case of rapid progressive atypical carcinoid of the lung discovered with multiple nodular shadows

An autopsy case of rapid progressive atypical carcinoid of the lung discovered with multiple nodular shadows 142 CASE REPORT An utopsy cse of rpid progressive typicl crcinoid of the lung discovered with multiple nodulr shdows Yoshio Okno*, Mmi Inym*, Nouo Htkeym*, Hiroyuki Hino*, Yoshito Iwhr*, Tokuji Motoki*,

More information

The Prevalence of Bacteremia in Pediatric Patients With Community-Acquired Pneumonia: Guidelines to Reduce the Frequency of Obtaining Blood Cultures

The Prevalence of Bacteremia in Pediatric Patients With Community-Acquired Pneumonia: Guidelines to Reduce the Frequency of Obtaining Blood Cultures RESEARCH ARTICLE The revlence of Bcteremi in editric tients With Community-Acquired neumoni: Guidelines to Reduce the Frequency of Obtining Blood Cultures bstrct OBJECTIVE: The gol of this study ws to

More information

Case Report Acute Zonal Occult Outer Retinopathy with Atypical Findings

Case Report Acute Zonal Occult Outer Retinopathy with Atypical Findings Cse Reports in Medicine Volume 24, Article ID 29696, 7 pges http://dx.doi.org/.55/24/29696 Cse Report Acute Zonl Occult Outer Retinopthy with Atypicl Findings Dimitrios Krginnis, Georgios A. Kontdkis,

More information

Clinical statistics analysis on the characteristics of pneumoconiosis of Chinese miner population

Clinical statistics analysis on the characteristics of pneumoconiosis of Chinese miner population Originl Article Clinicl sttistics nlysis on the chrcteristics of pneumoconiosis of Chinese miner popultion Mei-Fng Wng 1 *, Run-Ze Li 2 *, Ying Li 2, Xue-Qin Cheng 1, Jun Yng 1, Wen Chen 3, Xing-Xing Fn

More information

UC Davis UC Davis Previously Published Works

UC Davis UC Davis Previously Published Works UC Dvis UC Dvis Previously Published Works Title Rib hed protrusion into the centrl cnl in type 1 neurofibromtosis Permlink https://escholrship.org/uc/item/8457m5x3 Journl Peditric Rdiology, 40(12) ISSN

More information

Lung cancer is the leading cause of cancer death worldwide, EGFR Mutation and Brain Metastasis in Pulmonary Adenocarcinomas

Lung cancer is the leading cause of cancer death worldwide, EGFR Mutation and Brain Metastasis in Pulmonary Adenocarcinomas Originl Article EGFR Muttion nd Brin Metstsis in Pulmonry Adenocrcinoms Dong-Yeop Shin, MD,* Im Il N, MD,* Cheol Hyeon Kim, MD, PhD, Sunhoo Prk, MD, PhD, HeeJong Bek, MD, PhD, nd Sung Hyun Yng, MD, PhD*

More information

Symptomatic Remote Cyst after BCNU Wafer Implantation for Malignant Glioma

Symptomatic Remote Cyst after BCNU Wafer Implantation for Malignant Glioma Cse Report doi: 10.2176/nmc.cr.2017-0218 Neurol Med Chir (Tokyo) 58, 270 276, 2018 Symptomtic Remote Cyst fter BCNU Wfer Implnttion for Mlignnt Gliom Online My 21, 2018 Hideki MATSUMURA, 1 Eiichi ISHIKAWA,

More information

A rare case of a spontaneously ruptured secondary hepatic malignant lymphoma

A rare case of a spontaneously ruptured secondary hepatic malignant lymphoma Oshit et l. Surgicl Cse Reports (2018) 4:44 https://doi.org/10.1186/s40792-018-0451-2 CASE REPORT Open Access A rre cse of spontneously ruptured secondry heptic mlignnt lymphom Ko Oshit 1, Toshiyuki Itmoto

More information

Diagnostic aspects of invasive Aspergillus infections in allogeneic BMT recipients

Diagnostic aspects of invasive Aspergillus infections in allogeneic BMT recipients (2000) 25, 867 871 2000 Mcmilln Publishers Ltd All rights reserved 0268 3369/00 $15.00 www.nture.com/bmt Dignostic spects of invsive Aspergillus infections in llogeneic BMT recipients E Jntunen 1,2, A

More information

General Microscopic Changes

General Microscopic Changes Generl Microscopic Chnges 2 This chpter covers collection of microscopic chnges tht lck dignostic specificity ut occur in different specific diseses, s will ecome pprent in susequent chpters. Almost ll

More information

The potential future of targeted radionuclide therapy: implications for occupational exposure? P. Covens

The potential future of targeted radionuclide therapy: implications for occupational exposure? P. Covens The potentil future of trgeted rdionuclide therpy: implictions for occuptionl exposure? Introduction: Trgeted Rdionuclide Therpy (TRT) Systemic tretment Molecule lbelled with rdionuclide delivers toxic

More information

Breast carcinomas: why are they missed?

Breast carcinomas: why are they missed? O r i g i n l A r t i c l e Singpore Med J 2006; 47(10) : 851 Brest crcinoms: why re they missed? Muttrk M, Pojchmrnwiputh S, Chiwun B ABSTRACT Introduction: Mmmogrphy hs proven to e n effective modlity

More information

Postinfective physeal bars MRI features and choice of management

Postinfective physeal bars MRI features and choice of management Postinfective physel rs MRI fetures nd choice of mngement Murry Hyes, MB ChB Svvs Andronikou, MB BCh, FC Rd, FRCR, PhD Crey Mckenzie, MB ChB, FCRd Jco du Plessis, MB ChB Reen George, MB BS, MMed Rd Slomine

More information

Findings in spontaneous intramural intestinal hematoma imaging

Findings in spontaneous intramural intestinal hematoma imaging Brief report Findings in spontneous intrmurl intestinl hemtom imging F. Mirs Azcón, A. Mrtínez Mrtínez, A. Sntigo Chinchill*, A. Medin Benítez, E. Ochndo Pulido nd M.A. Pérez Rosillo Imging deprtment,

More information

A case of pulmonary adenocarcinoma showing rapid progression of peritoneal dissemination after immune checkpoint inhibitor therapy

A case of pulmonary adenocarcinoma showing rapid progression of peritoneal dissemination after immune checkpoint inhibitor therapy Shinozki et l. BMC Cncer (2018) 18:620 https://doi.org/10.1186/s12885-018-4549-5 CASE REPORT A cse of pulmonry denocrcinom showing rpid progression of peritonel dissemintion fter immune checkpoint inhiitor

More information

Utility of 128-slice Multi-detector Spiral Computed Tomography in Detecting Spectrum of Involvement in Acute Pancreatitis

Utility of 128-slice Multi-detector Spiral Computed Tomography in Detecting Spectrum of Involvement in Acute Pancreatitis Originl Article Print ISSN: 2321-6379 Online ISSN: 2321-595X DOI: 10.17354/ijss/2017/353 Utility of 128-slice Multi-detector Spirl Computed Tomogrphy in Detecting Spectrum of Involvement in Acute Pncretitis

More information

A Case of Intraductal Papillary Mucinous Carcinoma in the Head of the Pancreas Associated With Absence of the Duct of Wirsung

A Case of Intraductal Papillary Mucinous Carcinoma in the Head of the Pancreas Associated With Absence of the Duct of Wirsung CASE REPORT A Cse of Intrductl Ppillry Mucinous Crcinom in the Hed of the Pncres Associted With Asence of the Duct of Wirsung Ismu Mkino, Tkhis Ymguchi, Mitsuyoshi Okzki, Tomohru Miyshit, Hidehiro Tjim,

More information

Multilocular cystic clear cell renal cell carcinoma imaging with histopathologic correlation

Multilocular cystic clear cell renal cell carcinoma imaging with histopathologic correlation CASE REPORT J. Trnsl. Med. Res 2015;20(4):253-257 Multiloculr cystic cler cell renl cell crcinom imging with histopthologic correltion Emi Mrinel Pred 1,3, Ion Griel Lupescu 1,3, Adrin Dijmrescu 3, Gelu

More information

Recurrent Giant Phyllodes Tumour in a Young Female: A Case Report

Recurrent Giant Phyllodes Tumour in a Young Female: A Case Report CASE REPORT J. Trnsl. Med. Res 2016;21(3):210-214 DOI: 10.21614/jtmr-21-3-96 Recurrent Gint Phyllodes Tumour in Young Femle: A Cse Report Mhim Koshriy 1, Ashish Shrm 1, Ajy Gehlot 1, Surhi Grg 1, M.C.

More information

Effect of fungicide timing and wheat varietal resistance on Mycosphaerella graminicola and its sterol 14 α-demethylation-inhibitorresistant

Effect of fungicide timing and wheat varietal resistance on Mycosphaerella graminicola and its sterol 14 α-demethylation-inhibitorresistant Effect of fungicide timing nd whet vrietl resistnce on Mycospherell grminicol nd its sterol 14 α-demethyltion-inhiitorresistnt genotypes Didierlurent L., Roisin-Fichter C., Snssené J., Selim S. Pltform

More information

Two cases of pulmonary paragonimiasis on FDG-PET CT imaging

Two cases of pulmonary paragonimiasis on FDG-PET CT imaging CASE REPORT Annls of Nucler Medicine Vol. 20, No. 4, 311 315, 2006 Two cses of pulmonry prgonimisis on FDG-PET CT imging Ie Ryung YOO, Hyun Jin PARK, Joo HYUN O, Yong An CHUNG, Hyung Sun SOHN, Soo Kyo

More information

Bright Futures Medical Screening Reference Table 2 to 5 Day (First Week) Visit

Bright Futures Medical Screening Reference Table 2 to 5 Day (First Week) Visit Bright Futures Medicl Reference Tle 2 to 5 Dy (First Week) Visit Universl Action Metolic nd Verify documenttion of neworn metolic screening results, pproprite rescreening, nd needed follow-up. Document

More information

Calcifying nested stromal-epithelial tumor (CNSET) of the liver

Calcifying nested stromal-epithelial tumor (CNSET) of the liver Cse report (CNSET) of the liver Victor Inole 1, Loredn Betrice Ungurenu *,1, Eugeni Moroșn 1, Cristin Dumitru Lupșcu 1,2 1 Grigore T. Pop University of Medicine nd Phrmcy, Isi, Romni; 2 Deprtment of Surgery,

More information

The Selective Arterial Calcium Injection Test is a Valid Diagnostic Method for Invisible Gastrinoma with Duodenal Ulcer Stenosis: A Case Report

The Selective Arterial Calcium Injection Test is a Valid Diagnostic Method for Invisible Gastrinoma with Duodenal Ulcer Stenosis: A Case Report Hiroshim J. Med. Sci. Vol. 65, No. 1, 13~17, Mrch, 2016 HIJM 65 3 13 The Selective Arteril Clcium Injection Test is Vlid Dignostic Method for Invisile Gstrinom with Duodenl Ulcer Stenosis: A Cse Report

More information

CASE REPORT. Abstract. Introduction. Case Report

CASE REPORT. Abstract. Introduction. Case Report CASE REPORT Pulmonry Tumor Thromotic Microngiopthy Cused y Urothelil Crcinom Expressing Vsculr Endothelil Growth Fctor, Pltelet-derived Growth Fctor, nd Osteopontin Ysushi Wkyshi 1, Mi Iwy 2, Myo Akit

More information

Study of Stress Distribution in the Tibia During Stance Phase Running Using the Finite Element Method

Study of Stress Distribution in the Tibia During Stance Phase Running Using the Finite Element Method Ksetsrt J. (Nt. Sci.) 48 : 729-739 (2014) Study of Stress Distriution in the Tii During Stnce Phse Running Using the Finite Element Method Thepwchr Ruchirh 1, Tumrong Puttpitukporn 1, * nd Siriporn Ssimontonkul

More information

Mantle Cell Lymphoma with Atypical Radiologic Presentation: Case Report

Mantle Cell Lymphoma with Atypical Radiologic Presentation: Case Report Mntle Cell Lymphom with Atypicl Rdiologic Presenttion: Cse Report Linfom de céluls del mnto con presentción rdiológic típic: Presentción de cso Key words (MeSH) Lymphom, mntle-cell Lyphom Tomogrphy, X-ry

More information

University of Cape Town

University of Cape Town .. I i I II I I The copyright of this thesis vests in the uthor. No quottion from it or informtion derived from it is to be published without full cknowledgement of the source. The thesis is to be used

More information

The Dynamics of Varicella-Zoster Virus Epithelial Keratitis in Herpes Zoster Ophthalmicus

The Dynamics of Varicella-Zoster Virus Epithelial Keratitis in Herpes Zoster Ophthalmicus Chpter 2 The Dynmics of Vricell-Zoster Virus Epithelil Kertitis in Herpes Zoster Ophthlmicus The morphology of n individul VZV lesion reflects sequence of events triggered y the virus impct on cornel epithelil

More information

Intraventricular CNS lesions: A pictorial essay

Intraventricular CNS lesions: A pictorial essay s_s_nner Journl of Medicl Imging nd Rdition Oncology 59 (2015) 453 460 MEDICAL IMAGING PICTORIAL ESSAY Intrventriculr CNS lesions: A pictoril essy Jne Wtts, 1 Kelvin K Yp, 1 Dniel Ou, 2 Con Trtgli, 1 Nichols

More information

Original Article. T Akter 1, N Islam 2, MA Hoque 3, S Khanam 4, HA khan 5, BK Saha 6. Abstract:

Original Article. T Akter 1, N Islam 2, MA Hoque 3, S Khanam 4, HA khan 5, BK Saha 6. Abstract: Fridpur Med. Coll. J. 214;9(2):61-67 Originl Article Nebuliztion by Isotonic Mgnesium Sulphte Solution with Provide Erly nd Better Response s Compred to Conventionl Approch ( Plus Norml Sline) in Acute

More information

Concomitant Intraocular Retinoblastoma and Choroidal Hemangioma in a 1-Year-Old Boy

Concomitant Intraocular Retinoblastoma and Choroidal Hemangioma in a 1-Year-Old Boy Cse Report doi: 10.5146/tjpth.2017.01411 Concomitnt Introculr Retinoblstom nd Choroidl Hemngiom in 1-Yer-Old oy Ycoub A. Yousef 1, Mys Al-Hussini 2, Freed H. rkt 2, Al Sleh 3, Mon Mohmmd 1, Rsh Deebjh

More information

Am J Nephrol 2013;38: DOI: /

Am J Nephrol 2013;38: DOI: / Americn Journl of Nephrology Originl Report: Ptient-Oriented; Trnsltionl Reserch Am J Nephrol 213;38:333 341 Received: July 23, 213 Accepted: August 28, 213 Pulished online: Octoer 5, 213 Novel Approch

More information

Medical Thoracoscopy vs CT Scan-Guided Abrams Pleural Needle Biopsy for Diagnosis of Patients With Pleural Effusions

Medical Thoracoscopy vs CT Scan-Guided Abrams Pleural Needle Biopsy for Diagnosis of Patients With Pleural Effusions CHEST Originl Reserch PLEURAL DISEASE Medicl Thorcoscopy vs CT Scn-Guided Abrms Pleurl Needle Biopsy for Dignosis of Ptients With Pleurl Effusions A Rndomized, Controlled Tril Muzffer Metints, MD; Guntulu

More information

Effects of physical exercise on working memory and prefrontal cortex function in post-stroke patients

Effects of physical exercise on working memory and prefrontal cortex function in post-stroke patients Effects of physicl exercise on working memory nd prefrontl cortex function in post-stroke ptients M Moriy, C Aoki, K Sktni Grdute School of Helth Sciences Reserch, Mjor of Physicl Therpy, TeikyoHeisei

More information

Factors Affecting Concordance between Radiological and Histological Findings in Invasive Lobular Carcinoma Experience from a National Cancer Centre

Factors Affecting Concordance between Radiological and Histological Findings in Invasive Lobular Carcinoma Experience from a National Cancer Centre Originl Article DOI: 10.1159/000455066 Published online: Februry 7, 2017 Fctors Affecting Concordnce between Rdiologicl nd Histologicl Findings in Invsive Lobulr Crcinom Experience from Ntionl Cncer Centre

More information

Computed tomography findings of postoperative complications in lung transplantation*, **

Computed tomography findings of postoperative complications in lung transplantation*, ** Review Article Computed tomogrphy findings of postopertive complictions in lung trnsplnttion*, ** Achdos tomográficos ns complicções pós-opertóris do trnsplnte pulmonr Bruno Hochhegger, Klus Loureiro Irion,

More information

Case Report INTRODUCTION CASE REPORT. pissn eissn X

Case Report INTRODUCTION CASE REPORT. pissn eissn X pissn 2287-2728 eissn 2287-285X Cse Report Clinicl nd Moleculr Heptology 2018;24:424-429 Complete cure of dvnced heptocellulr crcinom with right drenl glnd metstsis nd portl vein thrombosis by multiple

More information

Intraductal Papillary Mucinous Neoplasm With Extensive Mural Osseous Metaplasia and Calcification

Intraductal Papillary Mucinous Neoplasm With Extensive Mural Osseous Metaplasia and Calcification CASE REPORT Intrductl Ppillry Mucinous Neoplsm With Extensive Murl Osseous Metplsi nd Clcifiction Runjn Chetty 1, Sngeeth N Klimuthu 1, Korosh Khlili 2 Deprtments of Pthology 1 nd Joint Deprtment of Medicl

More information

Chordoid Glioma Originating in the Intrasellar and Suprasellar Regions: Case Report

Chordoid Glioma Originating in the Intrasellar and Suprasellar Regions: Case Report pissn 2384-1095 eissn 2384-1109 imri 2015;19:117-121 http://dx.doi.org/10.13104/imri.2015.19.2.117 Chordoid Gliom Originting in the Intrsellr nd Suprsellr Regions: Cse Report Jisun Hwng 1, Aleum Lee 1,

More information

Slipped capital femoral epiphysis (SCFE) commonly

Slipped capital femoral epiphysis (SCFE) commonly IJOrtho R EP done on // 0 Cse Report Pseudohypoprthyroidism s rre cuse of ilterl slipped cpitl femorl epiphysis Krthikeyn R Somsundrm, Senthilkumr Snkrrmn, Athr Siddiqui, Hmid Zdeh Astrct Slipped cpitl

More information

Analysis of 18 F-fluorodeoxyglucose positron emission tomography findings in patients with pituitary lesions

Analysis of 18 F-fluorodeoxyglucose positron emission tomography findings in patients with pituitary lesions ORIGINAL ARTICLE Koren J Intern Med 2013;28:81-88 http://dx.doi.org/10.3904/kjim.2013.28.1.81 Anlysis of F-fluorodeoxyglucose positron emission tomogrphy findings in ptients with pituitry lesions Hnnh

More information

chapter 3. Squamous intraepithelial lesions: cytology histology correlation

chapter 3. Squamous intraepithelial lesions: cytology histology correlation chpter 3. Squmous intrepithelil lesions: cytology histology correltion CHAPTER 1 This chpter discusses the nturl history of cervicl precncer, HPV nd oncogenesis, cytology nomenclture, nd the cytologicl

More information

Check your understanding 3

Check your understanding 3 1 Wht is the difference etween pssive trnsport nd ctive trnsport? Pssive trnsport is the movement of prticles not requiring energy. Movement of prticles in ctive trnsport uses energy. 2 A gs tp in the

More information

imri 2015;19:

imri 2015;19: pissn 2384-1095 eissn 2384-1109 imri 2015;19:241-247 http://dx.doi.org/10.13104/imri.2015.19.4.241 Pncretic Arteriovenous Mlformtion s n Unusul Cuse of Chronic Gstrointestinl Bleeding in Ptient with Erly

More information

Differences in Disease Expression Between Primary Ciliary Dyskinesia and Cystic Fibrosis With and Without Pancreatic Insufficiency

Differences in Disease Expression Between Primary Ciliary Dyskinesia and Cystic Fibrosis With and Without Pancreatic Insufficiency CHEST Originl Reserch GENETIC AND DEVELOPMENTAL DISORDERS Differences in Disese Expression Between Primry Ciliry Dyskinesi nd Cystic Fibrosis With nd Without Pncretic Insufficiency Mlen Cohen-Cymberknoh,

More information

Non-invasive Diagnosis of Liver Clinical Condition by Real-time Tissue Elastography and Shear Wave Measurement : Get More Accessible by One Probe

Non-invasive Diagnosis of Liver Clinical Condition by Real-time Tissue Elastography and Shear Wave Measurement : Get More Accessible by One Probe XXXXXXXXXX Non-invsive Dignosis of Liver Clinicl Condition y Rel-time Tissue Elstogrphy nd Sher Wve Mesurement : Get More Accessile y One Proe Norihis Yd Mstoshi Kudo Deprtment of Gstroenterology nd Heptology,

More information

Efficacy of Pembrolizumab in Patients With Advanced Melanoma With Stable Brain Metastases at Baseline: A Pooled Retrospective Analysis

Efficacy of Pembrolizumab in Patients With Advanced Melanoma With Stable Brain Metastases at Baseline: A Pooled Retrospective Analysis Efficcy of Pembrolizumb in Ptients With Advnced Melnom With Stble Brin Metstses t Bseline: A Pooled Retrospective Anlysis Abstrct 1248PD Hmid O, Ribs A, Dud A, Butler MO, Crlino MS, Hwu WJ, Long GV, Ancell

More information

Methotrexate-associated Lymphoproliferative Disorder of the Stomach Presumed to Be Mucosa-associated Lymphoid Tissue Lymphoma

Methotrexate-associated Lymphoproliferative Disorder of the Stomach Presumed to Be Mucosa-associated Lymphoid Tissue Lymphoma doi: 10.2169/internlmedicine.0737-18 Intern Med 57: 3249-3254, 2018 http://internmed.jp CASE REPORT Methotrexte-ssocited Lymphoprolifertive Disorder of the Stomch Presumed to Be Mucos-ssocited Lymphoid

More information

EOSINOPHILIC PLEURAL EFFUSION IN ADULTS AT SRINAGARIND HOSPITAL

EOSINOPHILIC PLEURAL EFFUSION IN ADULTS AT SRINAGARIND HOSPITAL EOSINOPHILIC PLEURAL EFFUSION IN ADULTS AT SRINAGARIND HOSPITAL Wip Reechipichitkul nd Kittisk Chueskoolvnich Deprtment of Medicine, Sringrind Hospitl, Fculty of Medicine, Khon Ken University, Khon Ken,

More information

Lipase and Pancreatic Amylase Activities in Tissues and in Patients with Hyperamylasemia

Lipase and Pancreatic Amylase Activities in Tissues and in Patients with Hyperamylasemia CLINICAL CHEMISTRY Originl Article Lipse nd Pncretic Amylse Activities in Tissues nd in Ptients with Hypermylsemi FRED APPLE, PH.D, PETER BENSON, M.D., LYNNE PREESE, MT, M.B.A., STEVEN EASTEP, M.D., LAURA

More information

Inhaled Corticosteroid Is Associated With an Increased Risk of TB in Patients With COPD

Inhaled Corticosteroid Is Associated With an Increased Risk of TB in Patients With COPD CHEST Originl Reserch Inhled Corticosteroid Is Associted With n Incresed Risk of TB in Ptients With COPD Jung-Hyun Kim, MD ; Ji-Soo Prk, MD ; Kyung-Ho Kim, MD ; Hye-Cheol Jeong, MD ; Eun-Kyung Kim, MD

More information

308 nm excimer lamp in combination with topical tacrolimus: A retrospective study of its efficacy and safety in childhood vitiligo

308 nm excimer lamp in combination with topical tacrolimus: A retrospective study of its efficacy and safety in childhood vitiligo ORIGINAL ARTICLE 308 nm excimer lmp in comintion with topicl tcrolimus: A retrospective study of its efficcy nd sfety in childhood vitiligo BS Chndrshekr, N Shoh, P Deprtment of Dermtology, Cutis, Acdemy

More information

CheckMate 153: Randomized Results of Continuous vs 1-Year Fixed-Duration Nivolumab in Patients With Advanced Non-Small Cell Lung Cancer

CheckMate 153: Randomized Results of Continuous vs 1-Year Fixed-Duration Nivolumab in Patients With Advanced Non-Small Cell Lung Cancer CheckMte 53: Rndomized Results of Continuous vs -Yer Fixed-Durtion Nivolumb in Ptients With Advnced Non-Smll Cell Lung Cncer Abstrct 297O Spigel DR, McCleod M, Hussein MA, Wterhouse DM, Einhorn L, Horn

More information

Case report. Primary squamous cell carcinoma of the stomach

Case report. Primary squamous cell carcinoma of the stomach 136 Gstric Cncer (1999) 2: 136 141 S. Mrushi et l.: Primry squmous cell crcinom of the stomch 1999 y Interntionl nd Jpnese Gstric Cncer Associtions Cse report Primry squmous cell crcinom of the stomch

More information

Silicosis Appears Inevitable Among Former Denim Sandblasters A 4-Year Follow-up Study

Silicosis Appears Inevitable Among Former Denim Sandblasters A 4-Year Follow-up Study [ Originl Reserch Occuptionl nd Environmentl Lung Diseses ] Silicosis Appers Inevitble Among Former Denim Sndblsters A 4-Yer Follow-up Study Metin Akgun, MD, FCCP ; Omer Arz, MD ; Elif Yilmzel Ucr, MD

More information

Localized IgG4-related Cholecystitis Mimicking Gallbladder Cancer

Localized IgG4-related Cholecystitis Mimicking Gallbladder Cancer CASE REPORT Loclized IgG4-relted Cholecystitis Mimicking Gllldder Cncer Tdhis Inoue 1, Fumihiro Okumur 1, Tkshi Mizushim 1, Hirotd Nishie 1, Hiroysu Iwski 1, Kiki Ane 1, Tknori Ozeki 1, Kent Kchi 1, Shigeki

More information

Input from external experts and manufacturer on the 2 nd draft project plan Stool DNA testing for early detection of colorectal cancer

Input from external experts and manufacturer on the 2 nd draft project plan Stool DNA testing for early detection of colorectal cancer Input externl experts nd mnufcturer on the 2 nd drft project pln Stool DNA testing for erly detection of colorectl cncer (Project ID:OTJA10) All s nd uthor s replies on the 2nd drft project pln Stool DNA

More information

CYSTIC TUMORS OF THE PANCREAS

CYSTIC TUMORS OF THE PANCREAS gstrointestinl trct nd domen CYSTIC TUMORS OF THE PANCREAS Nichols J. Zyromski, MD Cystic tumors (neoplsms) of the pncres re fr more common thn once thought, developing in up to 10% of the generl popultion.

More information

Clear-cell variant of calcifying epithelial odontogenic tumor (Pindborg tumor) in the mandible

Clear-cell variant of calcifying epithelial odontogenic tumor (Pindborg tumor) in the mandible Interntionl Journl of Orl Science (2013) 5, 115 119 ß 2013 WCSS. All s reserved 1674-2818/13 www.nture.com/ijos CASE REPORT Cler-cell vrint of clcifying epithelil odontogenic tumor (Pindorg tumor) in the

More information

Stenosis or Occlusion of the Right Subclavian and Common Carotid Arteries Is More Common than That of the Innominate Artery in Takayasu Arteritis

Stenosis or Occlusion of the Right Subclavian and Common Carotid Arteries Is More Common than That of the Innominate Artery in Takayasu Arteritis Vsculr Specilist Interntionl Vol. 31, No. 4, December 2015 pissn 2288-7970 eissn 2288-7989 Stenosis or Occlusion of the Right Subclvin nd Common Crotid Arteries Is More Common thn Tht of the Innominte

More information

Impact of Positive Nodal Metastases in Patients with Thymic Carcinoma and Thymic Neuroendocrine Tumors

Impact of Positive Nodal Metastases in Patients with Thymic Carcinoma and Thymic Neuroendocrine Tumors Originl Article Impct of Positive Nodl Metstses in Ptients with Thymic Crcinom nd Thymic Neuroendocrine Tumors Benny Weksler, MD, Anthony Holden, MD, nd Jennifer L. Sullivn, MD Introduction: Thymic crcinoms

More information

Lung cancer is the leading cause of cancer-related deaths in

Lung cancer is the leading cause of cancer-related deaths in ORIGINAL ARTICLE Resection Rte nd Outcome of Pulmonry Resections for Non Smll-Cell Lung Cncer A Ntionwide Study From Icelnd Hunbogi Thorsteinsson, MD,* Asgeir Alexndersson, MD,* Gudrun N. Oskrsdottir,

More information

M form of true thymic hyperplasia [l], in which the

M form of true thymic hyperplasia [l], in which the ssive Thymic Hyperplsi Anthony G. Linegr, B, ChB, John A. Odell, RCS(Edin), W.. Pitt ennell, RCS(Eng), Puline. Close, RCPth, rk K. De Groot, RCS(C), Dennis R. Csserly, Ch, nd Joss I. Perold, ed(pth) Deprtment

More information

Skull fracture vs. accessory sutures: how can we tell the difference?

Skull fracture vs. accessory sutures: how can we tell the difference? Emerg Rdiol (2010) 17:413 418 DOI 10.1007/s10140-010-0877-8 PICTORIAL ESSAY Skull frcture vs. ccessory sutures: how cn we tell the difference? Thoms Snchez & Deorh Stewrt & Mtthew Wlvick & Leonrd Swischuk

More information

Influence of lateral cephalometric radiography in orthodontic diagnosis and treatment planning

Influence of lateral cephalometric radiography in orthodontic diagnosis and treatment planning Originl Article Influence of lterl cephlometric rdiogrphy in orthodontic dignosis nd tretment plnning An Reis Durão ; Ali Alqerbn b ; Afonso Pinhão Ferreir c ; Reinhilde Jcobs d ABSTRACT Objective: To

More information

Supplementary Online Content

Supplementary Online Content Supplementry Online Content Zulmn DM, Pl Chee C, Ezeji-Okoye SC, et l. Effect of n intensive outptient progrm to ugment primry cre for high-need Veterns Affirs ptients: rndomized clinicl tril. JAMA Intern

More information

Juvenile spondylodiscitis : the value of magnetic resonance imaging A report of two cases

Juvenile spondylodiscitis : the value of magnetic resonance imaging A report of two cases Act Orthop. Belg., 2004, 70, 627-631 CASE REPORT Juvenile spondylodiscitis : the vlue of mgnetic resonnce imging A report of two cses Herbert PLASSCHAERT, Kristof DE GEETER, Guy FABRY From the Deprtment

More information

Paper-based skin patch for the diagnostic screening of cystic fibrosis

Paper-based skin patch for the diagnostic screening of cystic fibrosis Electronic Supplementry Mteril (ESI) for ChemComm. This journl is The Royl Society of Chemistry 2015 Supplementry informtion Pper-bsed skin ptch for the dignostic screening of cystic fibrosis Xun Mu,*

More information

Papillary squamous cell carcinoma of the oral mucosa: immunohistochemical comparison with other carcinomas of oral mucosal origin

Papillary squamous cell carcinoma of the oral mucosa: immunohistochemical comparison with other carcinomas of oral mucosal origin 165 Journl Orl Science, Vol. 43, No. 3, 165-169, 2001 Ppillry orl mucos: immunohistochemicl comprison with or s orl mucosl origin Astrct: Ppillry (PSCC) is poorly descried vrint, nd my e confused with

More information

Relationship between bronchial anthracofibrosis and endobronchial tuberculosis

Relationship between bronchial anthracofibrosis and endobronchial tuberculosis ORIGINAL ARTICLE Koren J Intern Med 2013;28:330-338 Reltionship between bronchil nthrcofibrosis nd endobronchil tuberculosis Hyun Ji Kim, Sng Dong Kim, Dong Woo Shin, Soo Hyun Be, Ah Lim Kim, Ji N Kim,

More information

Sphincter-saving resection by cluneal arched skin incision for a gastrointestinal stromal tumor (GIST) of the lower rectum: a case report

Sphincter-saving resection by cluneal arched skin incision for a gastrointestinal stromal tumor (GIST) of the lower rectum: a case report Tzw et l. Surgicl Cse Reports (2017) 3:8 DOI 10.1186/s40792-016-0285-8 CASE REPORT Sphincter-sving resection y clunel rched skin incision for gstrointestinl stroml tumor (GIST) of the lower rectum: cse

More information

An Overlooked Potentially Treatable Disorder: Idiopathic Mesenteric Panniculitis

An Overlooked Potentially Treatable Disorder: Idiopathic Mesenteric Panniculitis Originl Pper Med Princ Prct 27;26:567 572 DOI:.59/48465 Received: Jnury 3, 27 Accepted: October 26, 27 Published online: October 26, 27 An Overlooked Potentilly Tretble Disorder: Idiopthic Mesenteric Pnniculitis

More information

Classic Papillary Thyroid Carcinoma with Tall Cell Features and Tall Cell Variant Have Similar Clinicopathologic Features

Classic Papillary Thyroid Carcinoma with Tall Cell Features and Tall Cell Variant Have Similar Clinicopathologic Features The Koren Journl of Pthology 2014; 48: 201-208 ORIGINAL ARTICLE Clssic Ppillry Thyroid Crcinom with Tll Cell Fetures nd Tll Cell Vrint Hve Similr Clinicopthologic Fetures Woo Jin Oh 1 Young Sub Lee 1 Uiju

More information

A large mediastinal benign myoepithelioma effacing the entire hemithorax: case report with literature review

A large mediastinal benign myoepithelioma effacing the entire hemithorax: case report with literature review Hshmi et l. Dignostic Pthology (2015) 10:100 DOI 10.1186/s13000-015-0340-y CASE REPORT A lrge medistinl enign myoepitheliom effcing the entire hemithorx: cse report with literture review Atif Ali Hshmi

More information

Introduction. These patients benefit less from conventional chemotherapy than patients identified as MMR proficient or microsatellite stable 3-5

Introduction. These patients benefit less from conventional chemotherapy than patients identified as MMR proficient or microsatellite stable 3-5 Nivolumb + Ipilimumb Combintion in Ptients With DNA Mismtch Repir-Deficient/Microstellite Instbility-High Metsttic Colorectl Cncer: First Report of the Full Cohort From CheckMte-142 Abstrct 553 André T,

More information

Immune Thrombocytopenia: A Rare Presenting Manifestation of Tuberculosis

Immune Thrombocytopenia: A Rare Presenting Manifestation of Tuberculosis Americn Journl of Hemtology 67:139 143 (2001) Immune Thrombocytopeni: A Rre Presenting Mnifesttion of Tuberculosis M.W. Ghobril* nd M.A. Albornoz Mercy Ctholic Medicl Center, Drby, Pennsylvni We report

More information

Precipitins and specific IgG antibody to

Precipitins and specific IgG antibody to 48 Thorx 1992;47:48-52 Precipitins nd specific IgG ntibody to Aspergillus fumigtus in chest unit popultion Deprtment of Immunology nd Osler Chest Unit, Churchill Hospitl, Oxford OX3 7LJ J A Fux D J Shle

More information

Brain Miliary Dissemination Pattern by Lung Adenocarcinoma: Case Report

Brain Miliary Dissemination Pattern by Lung Adenocarcinoma: Case Report Brin Miliry Dissemintion Pttern y Lung Adenocrcinom: Cse Report Ptrón de diseminción milir cererl por denocrcinom pulmonr: Presentción de cso Cmilo Andrés Lr Rodríguez 1 Ntli Rued-Ruiz 2 Key words (MeSH)

More information

Accuracy of Rotator Cuff Tears and Tendinosis Diagnoses on Shoulder Ultrasound Performed by a Short-experienced Operator

Accuracy of Rotator Cuff Tears and Tendinosis Diagnoses on Shoulder Ultrasound Performed by a Short-experienced Operator ORIGINAL ARTICLE Accurcy of Rottor Cuff Ters nd Tendinosis Dignoses on Shoulder Ultrsound Performed y Short-experienced Opertor Hrshd Arvind Vnjre, Jyoti Pnwr Deprtment of Rdiology, Christin Medicl College

More information

A Case of Triple Primary Malignancies Including the Breast, Pancreas, and Lung: The Role of 18 F-FDG PET/CT

A Case of Triple Primary Malignancies Including the Breast, Pancreas, and Lung: The Role of 18 F-FDG PET/CT A Cse of Triple Primry Mlignncies Including the Brest, Pncres, nd Lung: The Role of 18 F-FDG PET/CT Filiz HATİPOĞLU, Serp KARAARSLAN, İnnç KARAPOLAT, Atill ÇÖKMEZ c Deprtment of Nucler Medicine, Deprtment

More information

Copy Number ID2 MYCN ID2 MYCN. Copy Number MYCN DDX1 ID2 KIDINS220 MBOAT2 ID2

Copy Number ID2 MYCN ID2 MYCN. Copy Number MYCN DDX1 ID2 KIDINS220 MBOAT2 ID2 Copy Numer Copy Numer Copy Numer Copy Numer DIPG38 DIPG49 ID2 MYCN ID2 MYCN c DIPG01 d DIPG29 ID2 MYCN ID2 MYCN e STNG2 f MYCN DIPG01 Chr. 2 DIPG29 Chr. 1 MYCN DDX1 Chr. 2 ID2 KIDINS220 MBOAT2 ID2 Supplementry

More information

Preliminary and Short Report

Preliminary and Short Report TEE JOURNAL OF INVESTIGATIVE DREMATOLOOT Copyright 1967 by The Willims & Wilkins Co. Vol. 48 No. 3 Printed in U.S.A. Preliminry nd Short Report PARTICLES IN THE CISTERNAE OF THE ENDOPLASMIC RETICULUM OF

More information

Findings Regarding an Intracranial Hemorrhage on the Phase Image of a Susceptibility-Weighted Image (SWI), According to the Stage, Location, and Size

Findings Regarding an Intracranial Hemorrhage on the Phase Image of a Susceptibility-Weighted Image (SWI), According to the Stage, Location, and Size pissn 2384-1095 eissn 2384-1109 imri 2015;19:107-113 http://dx.doi.org/10.13104/imri.2015.19.2.107 Findings Regrding n Intrcrnil Hemorrhge on the Phse Imge of Susceptiility-Weighted Imge (SWI), According

More information