International Cartilage Repair Society
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1 OsteoArthritis and Cartilage (2005) 13, 738e743 ª 2005 OsteoArthritis Research Society International. Published by Elsevier Ltd. All rights reserved. doi: /j.joca Construct validity of the DynaPort Ò KneeTest: a comparison with observations of physical therapists 1 Lidwine B. Mokkink M.Sc.y, Caroline B. Terwee Ph.D.y*, Rob C. van Lummel M.Sc.z, Simon J. de Witte P.T.x, Leo Wetzels P.T.k, Lex M. Bouter Ph.D.y and Henrica C. W. de Vet Ph.D.y y Institute for Research in Extramural Medicine, VU University Medical Center, Amsterdam, The Netherlands z McRoberts B.V., The Hague, The Netherlands x Department of Physical therapy, Gemini Hospital, Den Helder, The Netherlands k Department of Physical therapy, Atrium Medical Center, Brunssum, The Netherlands Summary International Cartilage Repair Society Objective: To assess the construct validity of the DynaPort Ò KneeTest (KneeTest), which is a performance-based test to assess functioning of patients with knee osteoarthritis (OA). Scores on the KneeTest (KneeScore) were compared with observations of physical therapists of the patients functional disability. The reliability of these observations was also assessed. Method: Twelve physical therapists received identical video tapes showing the performance of 33 patients on the KneeTest. Each physical therapist rated the functional disability of each patient, performing the 23 activities of the KneeTest, on 23 Visual Analogue Scales (VAS activity ). The 23 VAS activity scores were averaged into a VAS average score. At the end of the test, an overall rating for the general performance of the patient was given on a VAS overall. Inter-observer Reliability was assessed for the VAS activity scores, VAS average, and the VAS overall. Results: Inter-observer reliability of the VAS average was higher (ICC 0.85, 95% CI 0.74e0.92) than the VAS overall (ICC 0.65, 95% CI 0.51e0.77). The correlation between the KneeScore and the VAS average, averaged over the 12 physiotherapists, was Conclusion: The construct validity of the KneeTest was supported by the strong correlation with the ratings of the patients disability by physical therapists. Given these findings and the high testeretest reliability of the KneeTest that was found in our previous study, we conclude that the KneeTest is a valid measure for assessing functioning in orthopedic and physical therapy research in patients with knee-oa before and after total knee replacement. Longitudinal validity has to be evaluated yet. ª 2005 OsteoArthritis Research Society International. Published by Elsevier Ltd. All rights reserved. Key words: Performance-based test, DynaPort Ò KneeTest, Validity, Reliability, Physical therapist. Introduction A number of measures are available to assess functioning of patients with knee osteoarthritis (OA). These can be divided into self-report questionnaires, clinical rating scales, and performance-based tests. A self-report questionnaire consists of items describing daily activities for which an individual is asked to indicate his/her perceived level of functioning. A clinical rating scale, a checklist or a onedimensional scale, in which a professional rates the patient in a standardized way. A performance-based test is one in 1 This study was financially supported by McRoberts B.V., and by the Royal Dutch Society for Physical Therapy (KNGF, Wetenschappelijk Fonds Fysiotherapie). Rob van Lummel (McRoberts B.V.) was involved in the design and execution of the study and commented on the manuscript, but he never had a veto on any decision and was not involved in the data analyses. *Address of correspondence and reprint requests to: C. B. Terwee, Institute for Research in Extramural Medicine (EMGO Institute), VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands. Tel: ; Fax: ; cb.terwee@vumc.nl Received 13 September 2004; revision accepted 12 April which an individual is asked to perform one or more specific tasks that are evaluated in a standardized manner using predefined criteria, such as counting repetitions or timing of the activities 1. Self-report questionnaires, e.g., the Western Ontario and McMaster University Osteoarthritis Index (WOMAC) 2 and the Medical Outcomes Study Short Form-36 Health Survey (SF-36) 3, measure the perceived limitations of patients in performing daily activities. Clinical rating scales, e.g., the Knee Society Score (KSS) 4, often include measures of functioning, e.g., limitations in walking and stair climbing, mostly based on self-report from patients. A variety of performance-based tests exist to measure functioning more objectively. In a systematic literature review (not published yet), we found tens of different walking tests, e.g., the 6-min walk test 5 and gait analyses 6, stair climb tests 5,7, and chair tests 8, and several different multiple-item tests, such as the test battery for physical activity restrictions (PAR) 9, the Iowa Level of Assistance Scale (ILAS) 10, and the method of Steultjens 11, that have been used to measure functioning of patients with knee-oa. Because of the conceptual differences between self-report questionnaires, clinical rating scales, and performance-based 738
2 Osteoarthritis and Cartilage Vol. 13, No. 8 tests, it has been suggested that self-report questionnaires as well as performance-based measures are required to evaluate function in patients with knee-oa comprehensively 12,13. In our systematic review, we found that none of the performance-based measures has been tested for all relevant measurement properties, i.e., content validity, internal consistency, reproducibility (both reliability and agreement), construct validity, responsiveness, floor and ceiling effects, and interpretability, and none of the measures received adequate ratings for the measurement properties that were tested. The DynaPort Ò KneeTest (KneeTest) 14 seems to be a promising performance-based measure for patients with knee-oa, undergoing total knee replacement (TKR). The test can be performed in a corridor in about 30 min. Patients perform a standardized set of activities, while accelerometers are used to measure functional parameters. In contrast to, e.g., gait analysis or more simple performancebased tests, the KneeTest contains multiple activitiesde.g., walking, stair climbing, sitting and rising, lifting and carrying objects, and picking up objects from the floordthat were selected to represent activities of daily living that are considered to be difficult for patients with knee problems and that have been identified as important by patients in focus group discussions 9. The scoring of the KneeTest is based on those test parameters that could significantly discriminate between patients and controls, such as accelerations, angles, durations, step number, step frequencies, relative speed and asymmetry, an approach that has been shown to be efficient and useful for the evaluation of function in TKR patients 15. Therefore, the content validity of the KneeTest is likely to be good. Recently, we determined the reproducibility and construct validity of the DynaPort Ò KneeTest (KneeTest) 16. We concluded that the KneeTest is a useful performancebased measure for research in patients with knee-oa, with good reliability and construct validity. Intraclass Correlation Coefficients (ICCs) for inter-observer and intra-observer reliability were 0.90 (0.83e0.94) and 0.95 (0.83e0.98), respectively. Construct validity was confirmed by expected correlations, expressed as Pearson s correlation coefficients (r), with the Western Ontario and McMaster University Osteoarthritis Index (WOMAC) physical functioning (r Z 0.55), Medical Outcomes Study Short Form-36 Health Survey (r Z SF-36) physical functioning (r Z 0.62) and KSS function (r Z 0.64). While this is a generally accepted method for assessing construct validity, the results are not very convincing. Moderate correlations between self-reported functioning and performance-based functioning are to be expected, but there are no accepted criteria for how large these correlations should be. We therefore decided that an alternative, more convincing validation approach was warranted. There is no gold standard available that measures quality of movement to validate the KneeTest against. In our opinion the observations of physical therapists of a patient s disability can be considered as a silver standard. Therefore, the aim of this study was to determine construct validity of the KneeTest by assessing correlations between the quality of movement measured with the KneeTest (expressed in the KneeScore) and the observations of physical therapists about the patient s functional disability during the performance of the test. Because we use this silver standard to validate the KneeTest, the ratings of the physical therapists must have a satisfactory inter-observer reliability. Therefore, our second aim was to determine the reliability of the physical therapist s disability ratings. Methods PATIENTS AND PROCEDURES Data were obtained from a reproducibility study in 92 patients 16, who were included if they (1) were diagnosed to have knee-oa, (2) were on the waiting list for a primary TKR or had received a TKR between 3 months and 5 years ago, (3) were able to speak and read Dutch, and (4) signed informed consent. All 92 patients included in the study were randomly assigned to one of the six physical therapists involved in the study. All 33 patients, who were assigned to two pre-determined physical therapists were asked if their performance of the KneeTest could by recorded on video, agreed. These 33 video registrations are the subject of this study. Our study was approved by the medical ethics committee of the VU University Medical Center. KNEETEST Patients performed the KneeTest under supervision of a physical therapist. During the test, patients perform 23 activities (Appendix A), while acceleration sensors are strapped around the trunk and legs. Standardized equipment is supplied such as wooden blocks, stairs of three steps, and a slope. For each activity, a selected set of functional parameters is being extracted from the signals of the acceleration sensors and the values of these parameters are being transformed and averaged into 23 activity scores. The activity scores were averaged into four cluster scores (locomotion, rise and descend, transfers, and lift and move objects, cf. Table I) and one total KneeScore, using a norm-based scoring procedure. Since the absolute measurement error of the four cluster scores is rather large 16, we suggest using only the total KneeScore in patient care. A score of 50 means that a patient scores similar to the mean of a healthy control group, a score of, e.g., 30 means that a person scores one standard deviation below the mean of the control group. Scoring of the test is done by an automated procedure in SPSS. The KneeTests were recorded on digital video with two fixed camera positions using the same camera for all patients. In advance, we determined the best camera positions and marked these spots. The digitalized video recordings of the performances of the KneeTest were copied on CD ROM in Table I Patient characteristics Patients (n Z 33) Men (%) 9 (27%) Age in yearsdmean (SD) 68 (9.7) Preoperative patients (n) 14 Postoperative patients (n) 19 Number of patients with both legs affected (%) 8 (24%) Education status Low 22 Middle 11 High 0 WOMAC pain scoredmean (SD) 31.3 (24.5) WOMAC stiffness scoredmean (SD) 39.8 (23.7) WOMAC function scoredmean (SD) 40.0 (24.0) KSS pain scoredmean (SD) 57.0 (36.2) KSS function scoredmean (SD) (45.6) 739
3 740 L. B. Mokkink et al.: Validity of the DynaPort Ò KneeTest a low resolution (320! 240) and compressed in divx format. RATINGS BY PHYSICAL THERAPISTS Twelve physical therapists received an identical video tape showing the performance of the 33 patients on the KneeTest and were asked to rate the functional disability of each patient during the performance of the KneeTest. We selected physical therapists from three different groups, i.e., (1) three physical therapists with experience with the KneeTest and with patients with knee-oa, (2) six physical therapists without experience with the KneeTest, but with experience with patients with knee-oa, and (3) three students who will graduate in physical therapy within a year. This way, physical therapists with a broad range of experience were included. Physical therapists were asked to rate the functional disability of the patient performing the 23 items of the KneeTest one by one, after each activity, on a Visual Analogue Scale (VAS activity ), ranging from not able to perform (score of 0) up to able to perform without any difficulties (score of 100). After watching the entire test, the physical therapists were asked to rate the (dis)ability of the patient to perform the test as a whole on a similar VAS (VAS overall ). All patients were rated in the same order. As described above, in the KneeTest, the 23 activities are scored individually and averaged into a KneeScore. In a similar way, the 23 VAS activity scores were averaged into four VAS cluster scores, and a total score (VAS average ) was calculated as the average of the four VAS cluster scores, to enable comparison of this summarized score with the KneeScore. INTER-OBSERVER RELIABILITY AMONG PHYSICAL THERAPISTS To determine the inter-observer reliability of the VAS scores of the physical therapists Intraclass Correlation Coefficients (two-way random effects model, ICC agreement ) with 95% confidence intervals (CI) were calculated 17.An ICC of O0.70 was considered satisfactory 18. We calculated the inter-observer reliability of the 23 VAS activity scores, the VAS average, and the VAS overall. Intra-observer reliability was not measured. CONSTRUCT VALIDITY To determine construct validity of the KneeTest, we compared the KneeScore with the ratings of the patients functional disability by the physical therapists. For each activity, the VAS scores of the 12 physical therapists were averaged into a mean VAS activity per patient. The 23 activity scores of the KneeTest were correlated with the mean VAS activity of that activity. Next, we calculated a mean VAS average for each patient by averaging the 12 VAS average scores of the 12 physical therapists. In a similar way, we calculated a mean VAS overall for each patient by averaging the 12 VAS overall scores of the 12 physical therapists. Spearman correlations were subsequently calculated between the KneeScore, on one hand, and the mean VAS average and the mean VAS overall, on the other. Since several items of the 23 activity scores of the KneeTest and 23 mean VAS activity Scores were non-parametric data, we used Spearman s correlations for all comparisons. We expected strong correlations ( R 0.70). All correlations were first calculated using all 12 physical therapists, and subsequently repeated in the three subgroups of physical therapists. Results Nine men and 24 women, mean age 68 years (SD 9.7), performed the KneeTest and were recorded on video. Fourteen patients were preoperative and 19 patients were postoperative (between 3 and 24 months). Additional patient characteristics are shown in Table I. RELIABILITY AMONG PHYSICAL THERAPISTS Table II shows the inter-observer reliability of the 23 VAS activity scores, the VAS average (the mean of the 23 VAS activity scores), and the VAS overall (the rating of the test Table II Inter-observer reliability of the functional disability ratings by 12 physical therapists: 23 VAS activity scores, averaged in the VAS average, and an overall rating (VAS overall ) of the test as a whole ICC (95% CI) VAS activity Locomotion Walk 9 m Walk 9 m back and forth Walk 9 m Walk a longer distance Rise and descend Ascend and descend stairs started with NA leg Ascend and descend stairs started with A leg Ascend and descend a slope started with NA leg Ascend and descend a slope started with A leg Step up (NA leg) and down (A leg) a block (20 cm) Step up (NA leg) and down (A leg) a block (30 cm) Step up (NA leg) and down (A leg) a block (40 cm) Step up (A leg) and down (NA leg) a block (20 cm) Step up (A leg) and down (NA leg) a block (30 cm) Step up (A leg) and down (NA leg) a block (40 cm) Transfers Pick up a weight with NA side Pick up a weight with A side Sit down and stand up (40 cm) Sit down and stand up (30 cm) Lift and move objects Slalom with shopping trolley forward Slalom with shopping trolley backward Carry a tray with two cups Carry a bag on NA side Carry a bag on A side VAS average VAS overall NA Z not affected, A Z affected (0.51e0.78) 0.56 (0.40e0.71) 0.75 (0.63e0.85) 0.77 (0.66e0.87) 0.68 (0.54e0.80) 0.72 (0.59e0.83) 0.70 (0.57e0.81) 0.68 (0.54e0.80) 0.78 (0.67e0.87) 0.90 (0.84e0.94) 0.87 (0.81e0.92) 0.78 (0.68e0.87) 0.86 (0.79e0.92) 0.88 (0.82e0.93) 0.74 (0.63e0.84) 0.72 (0.60e0.83) 0.69 (0.55e0.81) 0.66 (0.54e0.79) 0.52 (0.36e0.68) 0.60 (0.45e0.74) 0.84 (0.76e0.91) 0.85 (0.77e0.91) 0.76 (0.64e0.85) 0.85 (0.74e0.92) 0.65 (0.51e0.77)
4 Osteoarthritis and Cartilage Vol. 13, No. 8 as a whole). Fifteen of the 23 VAS activity scores were considered to be reliable (ICC O 0.70). Three ICCs were considered relatively low, i.e., the ICC for slalom with a shopping trolley forward (ICC Z 0.52), walk 9 m back and forth (ICC Z 0.56), and slalom with a shopping trolley backward (ICC Z 0.60). The VAS average had good reliability (ICC Z 0.85), while the VAS overall was less reliable (ICC Z 0.65). CONSTRUCT VALIDITY Table III shows the correlations between the 23 activity scores of the KneeTest and the 23 mean VAS activity scores (averaged over the 12 physical therapists), and between the KneeScore and the mean VAS average and the mean VAS overall (averaged over the 12 physical therapists). Ten of the 23 correlations between the activity scores of the KneeTest and the mean VAS activity scores were strong ( R 0.70). Eight of the 23 correlations were moderate (between 0.60 and 0.70) and five correlations were low (!0.60). The correlations between the KneeScore and the mean VAS average and the mean VAS overall were strong (0.86 and 0.87, respectively). Table III Spearman correlations between the 23 activity scores of the KneeTest and the 23 mean VAS activity scores (averaged over the 12 physical therapists), and between the KneeScore and the mean VAS average and mean VAS overall (averaged over the 12 physical therapists) Mean VAS activity Correlation Locomotion Walk 9 m 0.62 Walk 9 m back and forth 0.51 Walk 9 m 0.68 Walk a longer distance 0.66 Rise and descend Ascend and descend stairs started with NA leg 0.69 Ascend and descend stairs started with A leg 0.78 Ascend and descend a slope started with NA leg 0.73 Ascend and descend a slope started with A leg 0.69 Step up (NA leg) and down (A leg) a block (20 cm) 0.70 Step up (NA leg) and down (A leg) a block (30 cm) 0.86 Step up (NA leg) and down (A leg) a block (40 cm) 0.75 Step up (A leg) and down (NA leg) a block (20 cm) 0.64 Step up (A leg) and down (NA leg) a block (30 cm) 0.62 Step up (A leg) and down (NA leg) a block (40 cm) 0.79 Transfers Pick up a weight with NA side 0.80 Pick up a weight with A side 0.81 Sit down and stand up (40 cm) 0.52 Sit down and stand up (30 cm) 0.72 Lift and move objects Slalom with shopping trolley forward 0.62 Slalom with shopping trolley backward 0.70 Carry a tray with two cups 0.49 Carry a bag on NA side 0.43 Carry a bag on A side 0.50 Mean VAS average 0.86 Mean VAS overall 0.87 NA Z not-affected leg, A Z affected leg. Discussion The aim of the study was to determine construct validity of the DynaPort Ò KneeTest by comparing the scores of the KneeTest with ratings of physical therapists of functional disability of patients with knee-oa. In advance, we assessed the reliability of these observations. We found moderate reliability among the physical therapists on the ratings of the individual activities. Fifteen of the 23 ICCs were acceptable (O0.70). Items with low ICCs are not reproducible, and therefore they cannot be valid. However, when the ratings of the 23 activities were averaged, this VAS average was found to be highly reliable (ICC Z 0.85 with 95% CI 0.74e0.92). The overall rating of the test as a whole (VAS overall ) was less reliable (ICC Z 0.65 with 95% CI 0.51e0.77). This could be due to the fact that the physical therapists implicitly weight the activities differently, when giving a VAS overall score. The construct is measured in more detail when each activity is rated independently. It implies that a reliable rating about the patients functional disability requires a detailed rating of different activities, as measured with the VAS average. Moreover, the VAS average is the average of 23 ratings, so the measurement error is smaller for statistical reasons. The VAS average was considered to be the most reliable measure to draw conclusion about the construct validity of the KneeTest. The correlation of the mean VAS average, averaged over the 12 physiotherapists, with the KneeScore was 0.86, which strongly supports the construct validity of the KneeTest. The correlation of the KneeScore with the VAS overall was equally high, but the VAS overall was less reliable. A limitation of our study is that the physical therapists with experience of the KneeTest knew some of the patients and their history because they or one of their colleagues treated these patients. However, the reliability in the different subgroups of physical therapists was quite similar (data not shown). A second limitation of the study is that physical therapists rated all patients in the same order, so systematic bias may have been introduced because learning effects may have influenced the rating of the last patient by the physical therapists. In our previous study, first evidence of construct validity was provided by correlations with different questionnaires. The present study provided strong additional evidence for the construct validity of the KneeTest by expected correlations with a silver standard, i.e., observations of physical therapists. Given these findings and the high testeretest reliability of the KneeTest that was found in our previous study, we conclude that the KneeTest has good reliability and construct validity for use in orthopedic and physical therapy research in patients with knee-oa before and after TKR. However, longitudinal validity (responsiveness) has to be tested yet. Application of the KneeTest in other patient populations would require additional clinimetric testing, as reproducibility and validity are dependent upon the study population. Acknowledgements 741 We would like to thank Robert Pütz, Markus Wallach and Christian Zimpel for their time and effort to make and copy the video recordings, recruit physical therapists to participate in this study, for data collection, data entry, and initial data analyses.
5 742 L. B. Mokkink et al.: Validity of the DynaPort Ò KneeTest Appendix A. Activities of the DynaPort Ò KneeTest Cluster Activity Specification Locomotion 1 * Walk 9 m (first time, cf. activity 3) 2 Walk 9 m back and forth walk 9 m, turn, walk back 3 Walk 9 m (second time, cf. activity 1) 4 Walk a longer distance walk through a corridor (if available) and back (in total G 50 m) Rise and descend 5 Ascend and descend stairs (three steps, start with the NA leg each 20 cm high) 6 Ascend and descend stairs start with the A leg 7 Ascend and descend slope 120 cm long start with NA leg (with 33% inclination) 8 Ascend and descend slope start with A leg 9 Step up and down a block 20 cm, up with NA leg, down with A 10 Step up and down a block 30 cm, up with NA leg, down with A 11 Step up and down a block 40 cm, up with NA leg, down with A 12 Step up and down a block 20 cm, up with A leg, down with NA 13 Step up and down a block 30 cm, up with A leg, down with NA 14 Step up and down a block 40 cm, up with A leg, down with NA Transfers 15 Pick up a 4 kg weight walk to it, pick it up with NA side, go on walking 16 Pick up a 4 kg weight walk to it, pick it up with A side, go on walking 17 Sit down and stand up on and from block of 40 cm height 18 Sit down and stand up on and from block of 30 cm height Lift and move objects 19 Slalom with shopping trolley (with 50 kg in it) 9 m forwards slalom around 2 plastic cones 20 Slalom with shopping trolley 9 m backwards slalom around 2 plastic cones 21 Carry a tray with two cups walk 9 m straight, carrying the tray 22 Carry a 5 kg shopping bag walk 9 m straight, carrying the bag on NA side 23 Carry a 5 kg shopping bag walk 9 m straight, carrying the bag on A side NA Z not-affected leg, A Z affected leg. * A patient performs the activity walk 9 m in the beginning and the end of the test. References 1. Guralnik JM, Branch LG, Cummings SR, Curb JD. Physical performance measures in aging research. J Gerontol 1989;44:M141e6. 2. Bellamy N, Buchanan WW, Goldsmith CH, Campbell J, Stitt LW. Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol 1988;15:1833e Ware JE Jr, Sherbourne CD. The MOS 36-item shortform health survey (SF-36). I. Conceptual framework and item selection. Med Care 1992;30:473e Insall JN, Dorr LD, Scott RD, Scott WN. Rationale of the Knee Society clinical rating system. Clin Orthop Relat Res 1989;13e4. 5. Parent E, Moffet H. Comparative responsiveness of locomotor tests and questionnaires used to follow early recovery after total knee arthroplasty. Arch Phys Med Rehabil 2002;83:70e Fransen M, Crosbie J, Edmonds J. Reliability of gait measurements in people with osteoarthritis of the knee. Phys Ther 1997;77:944e Kreibich DN, Vaz M, Bourne RB, Rorabeck CH, Kim P, Hardie R, et al. What is the best way of assessing outcome after total knee replacement? Clin Orthop Relat Res 1996;221e5. 8. Lin YC, Davey RC, Cochrane T. Tests for physical function of the elderly with knee and hip osteoarthritis. Scand J Med Sci Sports 2001;11:280e6. 9. Rejeski WJ, Ettinger WH Jr, Schumaker S, James P, Burns R, Elam JT. Assessing performance-related disability in patients with knee osteoarthritis. Osteoarthritis Cartilage 1995;3:157e Shields RK, Enloe LJ, Evans RE, Smith KB, Steckel SD. Reliability, validity, and responsiveness of functional tests in patients with total joint replacement. Phys Ther 1995;75:169e Steultjens MP, Dekker J, van Baar ME, Oostendorp RA, Bijlsma JW. Internal consistency and validity of an observational method for assessing disability in mobility in patients with osteoarthritis. Arthritis Care Res 1999;12:19e Kennedy D, Stratford PW, Pagura SM, Walsh M, Woodhouse LJ. Comparison of gender and group differences in self-report and physical performance measures in total hip and knee arthroplasty candidates. J Arthroplasty 2002;17:70e Witvrouw E, Victor J, Bellemans J, Rock B, Van Lummel R, Van der Slikke R, et al. A correlation study of objective functionality and WOMAC in total knee
6 Osteoarthritis and Cartilage Vol. 13, No. 8 arthroplasty. Knee Surg Sports Traumatol Arthrosc 2002;10:347e Van den Dikkenberg N, Meijer OG, van der Slikke RM, van Lummel RC, van Dieen JH, Pijls B, et al. Measuring functional abilities of patients with knee problems: rationale and construction of the DynaPort knee test. Knee Surg Sports Traumatol Arthrosc 2002; 10:204e Chao EY, Laughman RK, Stauffer RN. Biomechanical gait evaluation of pre and postoperative total knee replacement patients. Arch Orthop Trauma Surg 1980; 97:309e Mokkink LB, Terwee CB, Van der Slikke RM, Van Lummel R, Benink RJ, Meijer OG, et al. Reproducibility and validity of the Dynaport Ò KneeTest. Arthritis Care Res (in press). 17. McGraw KO, Wong SP. Forming inferences about some intraclass correlation coefficients. Psychol Methods 1996;1:30e Lohr KN, Aaronson NK, Alonso J, Burnam MA, Patrick DL, Perrin EB, et al. Evaluating quality-of-life and health status instruments: development of scientific review criteria. Clin Ther 1996;18: 979e92.
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