EDWARDS RESEARCH GRANTS AND SUPPORT

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1 EDWARDS RESEARCH GRANTS AND SUPPORT Edwards served as the principal investigator or co-investigator on a number of National and International grants and commissions since 2009 with accumulated earning amount to over $9 million including competitive research grants, commissions and two ongoing project funds. Current Grants National Institute of Health-NIH U01NS Tele-rehabilitation in the home versus therapy in-clinic for patients with stroke National Institute of Health-NIH R03HD Transcranial direct current stimulation and robotic training in adults with cerebral palsy. Role: Co-Principal Investigator. Percent Effort: 40% Amount: US $194, Canadian Institutes of Health Research-MOP Non-invasive repeated therapeutic stimulation for aphasia recovery (NORTHSTAR) New York State Improving hand function in chronic stroke with combined robotic training and transcranial direct current stimulation Ekso Bionics, Inc. Walking improvement for SCI with exoskeleton (WISE Trial) Nexstim Inc. rtms and intensive upper limb therapy in chronic stroke (E-Fit Trial) MicroTransponder Inc. VNS and intensive upper limb therapy in chronic stroke

2 RESEARCH GRANT AND SUPPORT continued Edith Cowan University Early Career Researcher Grant Is therapeutic brain stimulation during exercise therapy effective for enhancing functional agonist/antagonist muscle coordination in the treatment of spasticity? Percent Effort: 100% Amount: AU $14, The Western Australian Institute for Medical Research & The Road Safety Council Neurotrauma Research Program Grant Can interventional brain stimulation improve motor performance after stroke? Amount: AU $106, Edith Cowan University Collaborative Research Investigation of I-Wave periodicity Transcranial Magnetic Stimulant applied during voluntary movement Taisho Pharmaceutical Co. Ltd. (Japan) International Industry Grant Development of Methods to Assess Standing Fatigue Amount: US $106, The Western Australian Institute for Medical Research & The Road Safety Council Neurotrauma Research Program Grant Using brain stimulation to help recovery after spinal cord injury and stroke. Percent Effort: Consultant Amount: AU $201, Burke Foundation Non-Invasive Brain stimulation and Human Motor Control Laboratory Start-up Percent Effort: 70% Amount: US $950, National Institute of Health-NIH R21 HD Transcranial direct current stimulation and motor training in chronic stroke Amount: US $467,854

3 RESEARCH GRANT AND SUPPORT continued Adelson Foundation Grant Physiological assays of learning and memory Role: Associate Investigator Amount: US $100, Pathmaker Neurosystems Inc. Spinal Direct Current Stimulation Amount: US $50, Skirball Foundation Virtual Reality in Upper Extremity Motor Rehabilitation Amount: US $50, National Institute of Health-NIH R21 HD Non-invasive stimulation for improving motor function in spinal cord injury Amount: US $519, Nexstim Inc. rtms and intensive upper limb therapy in chronic stroke Amount: US $500, Train the Brain Foundation Robotics exoskeleton gait training in SCI and stroke Percent Effort: 20% Amount: US $600, National Institute of Health-NIH R01 HD Transcranial Direct Current Stimulation and Robotic Training in Chronic Stroke Percent Effort: 40% Amount: US $3,181,223

4 RESEARCH GRANTS AND SUPPORT continued Other Funding; Cumulative Grants; and Non-Funded Scientific Pilot Projects Other Funding Since 2008 Edwards laboratory received US$1 million from: private donors, Burke Hospital, Cornell University donors, and the Cornell Clinical and Translational Science Center (CTSC). Since the recent launch of the RNC robotics fee-for-service program in April 2013, the Restorative Neurology Clinic (RNC) at Burke has generated more than US$1 million. Cumulative Research Grants and Commissions Non-Funded Scientific Pilot Projects Edwards is actively involved in nearly 30 scientific ongoing pilot projects. He is responsible for designing, implementing and coordinating these projects. 1. Effects of tdcs on motor unit recruitment in affected hand muscles of chronic stroke patients, Burke Medical Research Institute and Spaulding Rehabilitation Hospital Boston. 2. Effects of tdcs on trigeminal nerve reflexes, Burke Medical Research Institute in USA, and Hospital Clinic in Barcelona, Spain. 3. Effects of High-Definition tdcs on kinematic performance in chronic stroke, Burke Medical Research Institute and Harvard Medical School, Boston, USA. 4. Modulation of spinal excitability with repetitive, paired Transcranial Magnetic Stimulation (TMS) and peripheral nerve stimulation, BRC 391.

5 RESEARCH GRANTS AND SUPPORT continued Non-Funded Scientific Pilot Projects 5. Evaluation and tracking of the natural history of homonymous hemianopsia/quadrantanopsia after a first clinically evident stroke or a previous stroke without visual involvement: An Observational Study, BRC The effect of TDCS on motor unit recruitment in chronic stroke, BRC Physiological assay of drugs and rehabilitation to augment learning and memory, BRC Transcranial direct current stimulation and robotic training in adults with cerebral palsy, BRC Pilot testing of the leap motion as an effective tool for upper limb rehabilitation in stroke, BRC Robotic training in any neurological impairment that causes arm/hand deficits, BRC Lower limb robot training for any neurological deficit that leads to impaired gat or balance, BRC Neurophysiological evaluation and lower limb robot training for neurological disorders leading to impaired gait or balance, BRC Development of an EEG analysis tool to determine the effectiveness of a TDCS protocol, BRC Non-Invasive repeated therapeutic stimulation for aphasia recovery (NORTHSTAR), BRC Transcranial direct current stimulation as an adjuvant to intensive speech therapy for chronic post stroke aphasia, BRC RETT Syndrome: measuring mechanical stiffness and impedance, BRC Telerehabilitation in the home versus therapy in-clinic for patients with stroke: an assessor-blind, randomized, non-inferiority trial, BRC Transcranial direct current stimulation as adjunctive pharyngeal dysphagia treatment in an acute rehabilitation setting, BRC Immersive virtual reality for chronic neuropathic pain after spinal cord injury: a feasibility trial, BRC Robotic therapy by trained volunteers for upper limb motor recovery following stroke: a pilot project, BRC Walking Improvement for SCI with exoskeleton (WISE trial), BRC Walkbot robotic training for improvement in gait in sub-acute stroke, BRC Burke-Hocoma efficiency study, BRC Electrical field navigated 1 Hz RTMS for post-stroke motor recovery (E-FIT trial), BRC Maraviroc to augment rehabilitation outcomes after stroke (MAROS trial), BRC Parkinson s, Robotics, and RTMS, BRC 546.