partment of General S urgery, West China Hos pital, S ichuan Universit y, Cheng du , China

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1 ( 2007) R R A Fast2Track Programmes of Multi2Disciplinary Team in Colorectal Surgery L IU Zhan, W A N G X iao2dong, L I L i. De2 partment of General S urgery, West China Hos pital, S ichuan Universit y, Cheng du , China Abstract Objective To explore the content and scientific evidence of every element of the fast2track pro2 grammes in colorectal surgery. Methods The literatures about the applied status and opinion of the modality applied in the surgical treatment of the colorectal cancer and fundament investigation in recent years were collected and re2 viewed. Results The feasibility of the every fast2track s element was based on the clinical and fundamental investi2 gaton. Conclusion The advantage of the fast2track programmes in colorectal surgery is confirmed. Key wordscolorectal surgery Fast2track programme Content Evidence (fast2track,ft) [1 ],, F T 1 [2,3 ],,,, / [4 ] :,, [5 ] 2 13 d FT, Brown2 son [6 ],, (), ; Baker 3 ( ) ; : ( ),,,, [7 ],, ; Santos [8 ] Schein [9 ],, ; Graney [10 ] h,, [11 ] ; [9 ],,, [12 ],,, [5,11,12 ] Slim [12 ] 2 h, 3, [13 ] FT, 6 h, 2 h ml [5 ]

2 Chin J Bases Clin General Surg, Vol. 14, No. 4, J uly 2007 [14 ], [15 ],, [16 ], [17 ] 4 Caumo [18 ],, ; Hausel [14 ], Meta [19 ], [5 ] 5,,, [20 ] 212 h,, [21 ] FT,,FT Lausen [21 ] [22,23 ] ; : 12 h, 28 h,,, ;, [5 ], 50 %, [5 ] 6 3 : ; ;, [5 ] 7 ( mid2thoraic epidural anaesthesia) T6T8 ( T9T10 ),(0. 25 % 4 ml/ h 0. 2 mg/ h), 4872 h [2426 ] Wilmore [27 ], Kehlet [28 ], 22, ( ),,,,, FT [24 ], ( ) [28 ],,Meta [29 ],,, [30 ] 8 F T [27 ], F T, [24,25,27,31,32 ] [24 ],, [33,34 ], [24 ] 9 F T ( ) [35 ],(combined effect) [24 ], [27 ] Schuster [35 ],, Mattei [24 ],, Wind [32 ], FT,, Basse [36 ], FT,,, F T [24 ] 10 Cheatham [37 ] Meta, [5 ] 26 Meta,,, [37 ], ( ) [24 ] ;

3 471 ;, [5 ] 11,,, 2 h,2 4,3 [38 ], (, ) [5 ], ( ) [39 ], [40 ] :, [27,32 ] 12,,,, [41 ] [42,43 ] ;,, [44 ] :, Basse [45 ], 1 d 2 d ; [46 ] ; 2 h, 800 ml, [5 ] 13 Urbach [47 ] Meta 14 [44 ] 24 h FT [5 ] 15 FT, 4 h (oral nutritional supplements,ons) (400 ml ), [5 ] [48 ],1224 h, 2448 h,35 d,, [24 ] FT, 1 d 4 d, [45,49,50 ],,, [51 ] ; [52,53 ],, Fearon [5 ] 16 FT ; Fearon [5 ], ; 2 h, 6 h, 17 F T : ;, ; ;,, F T Fearon [5 ],,,, 18 FT,23 d,10 %20 % 1 h [45,54 ] 24 h, (: ),,2448 h 710 d,: 30 d,, Fearon [5 ],F T, ; 1 % 3 %( ),,FT 19 F T,, FT [5 ] FT

4 Chin J Bases Clin General Surg, Vol. 14, No. 4, J uly ,,. [J ]., 2007 ; 14 (2) Egbert LD, Battit GE, Welch CE, et al. Reduction of postop2 erative pain by encouragement and instruction of patients. study of doctor2patient papport [J ]. N Engl J Med, 1964 ; 270 (4) Kiecolt2Glaser J K, Page GG, Marucha P T, et al. Psychological influences on surgical recovery. Perspectives from psychoneuro2 immunology [J ]. Am Psychol, 1998 ; 53 (11) Disbrow EA, Bennett HL, Owings J T, et al. Effect of preop2 erative suggestion on postoperative gast rointestinal motility [J ]. West J Med, 1993 ; 158 (5) Fearon KC, Ljungqvist O, Von Meyenfeldt M, et al. Enhanced recovery after surgery : a consensus review of clinical care for patients undergoing colonic resection [J ]. Clin Nutr, 2005 ; 24 (3) Brownson P, Jenkins S, Nott D, et al. Mechanical bowel prep2 aration before colorectal surgery : results of a prospective ran2 domized trial [J ]. Br J Surg, 1992 ; 79 (3) Baker L W, Thomson SR, Chadwick SJ. 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5 Kehlet H, Dahl JB. Anaest hesia, surgery, and challenges in postoperative recovery [J ]. Lancet, 2003 ; 362 (9399) Miedema BW, Johnson J O. Met hods for decreasing postopera2 tive gut dysmotility [J ]. Lancet Oncol, 2003 ; 4 (6) Schuster T G, Montie J E. Postoperative ileus after abdominal surgery [J ]. Urology, 2002 ; 59 (4) Basse L, Jakobsen D H, Bardram L, et al. Functional recovery after open versus laparoscopic colonic resection : a randomized, blinded study [J ]. Ann Surg, 2005 ; 241 (3) Cheat ham ML, Chapman WC, Key SP, et al. A meta2analysis of selective versus routine nasogastric decompression after elec2 tive laparotomy [J ]. Ann Surg, 1995 ; 221 (5) Kurz A, Sessler DI, Lenhardt R. Perioperative normot hermia to reduce the incidence of surgical2wound infection and shorten hospitalization. Study of Wound Infection and Temperature Group [J ]. N Engl J Med, 1996 ; 334 (19) Frank SM, Fleisher LA, Breslow MJ, et al. Perioperative ma2 intenance of normot hermia reduces t he incidence of morbid car2 diac event s. A randomized clinical trial [J ]. J AMA, 1997 ; 277 (14) Sessler DI. Mild perioperative hypot hermia [J ]. N Engl J Med, 1997 ; 336 (24) Lobo DN, Bostock KA, Neal KR, et al. Effect of salt and wa2 ter balance on recovery of gastrointestinal function after elective colonic resection : a randomised controlled trial [J ]. Lancet, 2002 ; 359 (9320) Tambyraja AL, Sengupta F, Mac Gregor AB, et al. Patterns and clinical outcomes associated wit h routine intravenous sodi2 um and fluid administration after colorectal resection [J ]. World J Surg, 2004 ; 28 (10) Brandstrup B, Tonnesen H, Beier2Holgersen R, et al. Effect s of intravenous fluid restriction on postoperative complications : comparison of two perioperative fluid regimens : a randomized assessor2blinded multicenter trial [J ]. Ann Surg, 2003 ; 238 (5) Wilson J, Woods I, Fawcett J, et al. Reducing t he risk of ma2 jor elective surgery : randomised controlled trial of preoperative optimisation of oxygen delivery [J ]. BMJ, 1999 ; 318 (7191) Basse L, Hjort Jakobsen D, Billesbolle P, et al. A clinical pa2 thway to accelerate recovery after colonic resection [J ]. Surg, 2000 ; 232 (1) 51 Ann 46 Holte K, Foss NB, Svensen C, et al. Epidural anest hesia, hy2 potension, and changes in intravascular volume [J ]. Anest hesi2 ology, 2004 ; 100 (2) Urbach DR, Kennedy ED, Cohen MM. Colon and rectal anas2 tomoses do not require routine drainage : a systematic review and meta2analysis [J ]. Ann Surg, 1999 ; 229 (2) Livingston EH, Passaro EP. Postoperative ileus [J ]. Dig Dis Sci, 1990 ; 35 (1) Fearon KC, L uff R. The nutritional management of surgical pa2 tients : enhanced recovery after surgery [J ]. Proc Nutr Soc, 2003 ; 62 (4) Henriksen M G, Hansen HV, Hessov I. Early oral nutrition af2 ter elective colorectal surgery : influence of balanced analgesia and enforced mobilization [J ]. Nutrition, 2002 ; 18 (3) L uckey A, Livingston E, Tache Y. Mechanisms and t reat ment of postoperative ileus [J ]. Arch Surg, 2003 ; 138 (2) Holte K, Kehlet H. Postoperative ileus : progress towards ef2 fective management [J ]. Drugs, 2002 ; 62 (18) Kehlet H, Buchler MW, Beart RW J r, et al. Care after colonic operation is it evidence2based? Results from a multinational survey in Europe and the United States [J ]. J Am Coll Surg, 2006 ; 202 (1) Kehlet H, Wilmore DW. Multimodal strategies to improve sur2 gical outcome [J ]. Am J Surg, 2002 ; 183 (6) 630 ( , ) ( ), : com,

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