Novel methods and approaches for sensing, evaluating, modulating and regulating mood and emotional states.

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1 Nvel methds and appraches fr sensing, evaluating, mdulating and regulating md and emtinal states Jy Academic Grant Call fr Prpsals Intrductin The Annual Jy grant initiative aims t prmte and cntribute t the emerging field f neurwellness. The grant supprts research effrts that ptentially impact human perfrmance and wellbeing, imprve regulatin f emtins in persnal and scial cntext and increase mental and physical resilience under challenge which are all different aspects f neur-wellness. Neur-wellness fcuses n the research f imprving r enhancing the resilience f the healthy brain twards stress, emtinal imbalance and instability, and understanding their underlying mechanisms. Each year, a new grant theme will supprt research effrts that elucidate mechanisms that cmprise and cntribute t human wellness; generate new neur-wellness-related knwledge thrugh new implementatins f existing data; r use state f the art scientific tls, technlgies and new mdalities t generate new appraches fr sensing, mnitring and mdulating f the human brain and bdy Jy Grant Theme This year s grant theme will cver varius research aspects relating t characterizatin and identificatin f emtinal states and md alteratins in humans. Research prpsals that will be cnsidered fr the 2018 grant will include research, in varius stages, that will eventually prvide nvel slutins fr at least ne f the fllwing bjectives: Regulatin f emtinal states: Identify and characterize emtinal states; understand the mechanisms underlying emtin regulatin; research f psitive affect and prcesses that supprt and enhance frmatin f psitive habits. Nn-invasive methds t manage and imprve emtinal states and md- may include, but nt limited t sensry/bdily influences n such regulatin; neurmdulatin techniques, enhancement f brain plasticity. Nn-invasive, real-time sensing techniques, cntinuus mnitring and nn-invasive evaluatin f emtinal states May include, but nt limited t: Study f parameters frm varius anatmic structures (such as skin, face, muscles r eyes); 1

2 Cntinuus sensing f hrmnes and neurtransmitters; measurements f surrgate markers f emtinal states in humans Behaviral and scial data as surrgate markers fr emtinal state Multiparametric big data appraches fr understanding, mnitring and predicting vulnerability t dysregulated emtinal states r unstable md may include, but nt limited t setting new physilgical parameters, applying machine learning and artificial intelligence: making new sense ut f existing data sets (such as heart rate, GSR, EOG, EMG, ximetry, EEG) Eligibility The grant will supprt research perfrmed in academic educatin centers (universities and clleges) and medical research institutes in Israel. Cllabratins between varius academic disciplines, different Israeli research institutes, and/r with industry are highly encuraged. Internatinal cllabratins will be cnsidered. Applied apprach is encuraged. We welcme basic research prpsals as lng as the future applicatin f the research is clearly stated. We supprt studies n human subjects that ultimately target healthy ppulatins. Wh can apply fr the Jy academic grant? Lab heads and principal investigatrs Pst-dctral fellws PhD candidates (with supervisr apprval) Jint interdisciplinary teams frm any discipline are invited (neurscience, psychlgy, life sciences, medicine, engineering, cmputer science, physics, humanities and thers). Inter-disciplinary teams f researchers frm exact/life science, tgether with researchers frm scial sciences and humanities are encuraged. Abut Jy & The Jy Annual Grant Prgram Jy aims t facilitate the creatin f a jint, inter-disciplinary, cllabrative ecsystem between academia and industry. The gal is t implement the latest advancements in neurscience, related fields and technlgy fr imprving the everyday human experience and well-being by cultivating mental resilience and reducing mental vulnerability and allwing peple t cpe beneficially with 2

3 difficulties and challenges f daily life. This will allw peple t cpe with and better manage stress and negative emtins during their daily life. Jy s lng-term gal is t create slutins catering individuals directly, with n need fr FDA clearance r medical guidance/supervisin Mre infrmatin abut Jy Ventures The grant initiative is an annual effrt t supprt research in the neur-wellness field. This is the secnd year f the prgram. The prgram will prvide, each year, up t $1.2 millin dllars (in aggregate) funding, t prpsals cnsistent with the initiative's gals, thrugh a cmpetitive applicatin, review, and selectin prcess. Selected prpsals will be funded with amunts f $40,000-$100,000 per annum, fr a tw-year perid, beginning December 15, Research extensins shuld be applied fr up t 6 mnths prir t the end f the tw-year perid. The grant des nt supprt clinical studies and studies that fcus n mental r physical diseases. T get a better idea f supprted research see previus grant winners. A meeting explaining the grant applicatin and presenting the initiative including Q&A will be held, n January 22, t further elabrate n the annual grant theme and answer questins. Additinal infrmatin & inquiries: hagit@jyventures.cm JOY Grants - Guidelines 1. Criteria fr selecting prpsals: 1.1 Nvelty (20%) 1.2 Expected impact in the field (30%) 1.3 High research quality (20%) 1.4 Facility / Feasibility (10%) 1.5 Cllabratin amng varius disciplines and/ r industry r a high risk, high gain study (20%) 2. Scientific cmmittee: The Grants' cmmittee cnsists f leading researchers in the field (see ur website). The cmmittee will review and evaluate the prpsals, interview the leading prpsal researchers, t decide which prjects will be supprted, subject t apprval by Jy Bard f Directrs. 3

4 3. Timetable and Deadlines 2018 Call Publicatin Date: 2 January Q&A Meet-Up (attendance recmmended): 22 January LOI extended abstract submissin: 15 Feb Answers regarding next phase: by 25 Feb Prpsal Submissin Dead-Line: 10 April Secnd Phase Prpsals Ntificatin: 15 May Interviews w Leading Prpsal Researchers: June Winners Annuncement: 15 August Frmal Research Initiatin & Funding: 15 December 4. The letter f Intent (LOI) will include: An extended abstract f the prpsed research. The LOI will nt exceed 1 page and shuld cntain the fllwing elements: The mtivatin fr the research, methdlgy, expected utcme and expected impact. In additin, the abstract will prvide an explanatin abut the nvel aspects f the research, whether it is interdisciplinary in nature and/r high risk, high gain. The ne pager can include a figure but des nt include references, which can be submitted n a separate page. ½ a page abut yu and why yu/yur grup shuld execute the study. PhD students and pst-dc fellws will als include a separate letter f supprt frm their supervisr. Please submit the LOI t grant@jyventures.cm 5. The prpsal (upn apprval f LOI) will include: a) Cmpleted title page (see Appendix A) b) Shrt versin (2 page) CV f leading researchers invlved in the prpsal (Bisketch NIH frmat) c) An abstract summarizing the main prpsed bjectives. 4

5 d) Descriptin f the prpsed research prgram & expected utcme. e) Include the fllwing sectins in the prpsal Specific research gals - what is the prblem/experience t be researched and hw is it related t imprving the everyday human experience Ratinale fr the study; please state specifically what are the nvel aspects in the study and what is the expected impact t the field. Research plan and milestnes Cllabratin cntributins & respnsibilities Scientific apprach Preliminary relevant data (if exists) Expected results & utcmes Applicative ptential The prpsal (narrative & figures, but nt bibligraphy) shuld nt exceed 5 numbered, singlespaced pages, in 12-pint fnt with ne-inch margins. f) Detailed statement: A tabulated clumn/dllar amunt frmat f plans fr the full research term, including detailed itemized budgets fr each year. g) Statement/ apprval f the affiliated institute fr submitting the prpsal, by the financial fficer and/r research authrity, including applicants name. i) Nt mandatry: Vide Statement: in additin t the prpsal, researchers are encuraged t submit a 2-min vide statement presenting the highlights f their prject (ral statement r cmbined with a presentatin demnstratin). The vide statement will serve as part f the review prcess. Please send the abve dcuments t: grant@jyventures.cm 6. Secnd Phase - Best and Final Prpsals: The researchers f highest-ranked prpsals will be invited fr a presentatin + interview. In case the prpsed research invlves human and/r animal subjects, dcumentatin frm the affiliated research institutin that, such experimentatin has been apprved by the apprpriate institutinal cmmittee[s]. 5

6 7. Funds allcatin: Allwed salaries/schlarships may include thse fr pst-dctral, PhD r master students, research assistants, technical services & supprt. The grant funds may be used fr equipment & lab testing, supplies, animal csts & travel. The grant will accept allcatin f up t 20% fr institutinal verhead r indirect csts. 8. Reprting plicy: Annual written reprts, bth financial and scientific, including prgress, achievement, bstacles, etc. JOY Grant representatives reserve the rights t visit the researchers in their facility fr unfrmal pre-arranged peridic review meetings. 9. Payments are subject t an annual review f research prgress. The spnsring institute is respnsible fr fiscal management. Payment terms: 100% f the annual funding at the beginning f the first year f research (after cmpleting frmal apprval f terms and agreements and acceptance f an invice prduced by the research institute); 80% beginning f secnd research year upn apprval f first annual reprt; 20% after apprval f secnd annual reprt. Additinal infrmatin & inquiries: hagit@jyventures.cm. 6

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