LIVER CANCER: MANAGEMENT AND CHALLENGES

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1 The LIVER CANCER: MANAGEMENT AND CHALLENGES Hatch Auditorium Guggenheim Pavilion, 2nd Floor 1468 Madison Ave. at 100th St., New York, NY Program Director: Josep M. Llovet, MD Professor of Medicine Director, Sponsored by

2 The LIVER CANCER: MANAGEMENT AND CHALLENGES Hatch Auditorium, Guggenheim Pavilion, 2nd Floor 1468 Madison Avenue at 100th Street, New York, NY Program Director: Josep M Llovet, MD, Professor of Medicine Director, Program Chairs: Myron Schwartz, MD, Professor of Surgery Samuel Waxman, MD, Professor of Medicine Activity Description This conference will assemble multidisciplinary experts on hepatocellular carcinoma from the and four outstanding invited lecturers. The meeting is intended to provide a summary of the stateof-the-art knowledge of the pathogenesis and clinical management of hepatocellular carcinoma, and the research conducted in Mount Sinai. Activity Goals and Objectives At the conclusion of this activity, participants will be able to: n Provide information and data in order to reduce the gap between evidence-base knowledge and clinical practice. n Identify novel drugs in the field of HCC and key concepts to guide data analysis in clinical trials. n Discuss and validate relevant information about the discovery of novel targets for chemopreventive strategies and treatment of HCC. n Comprehend the current knowledge of cholangiocarcinoma and management to better inform the attendees about this disease. Registration Fee Complimentary. Register online at Target Audience Hepatologists and Gastroenterologist, Oncologists, Surgeons, Radiologists, Pathologists and Basic Scientists interested in liver cancer from the New York area. Accreditation is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Credit Designation designates this live educational activity for a maximum of 6.0 AMA PRA Category 1 Credit(s) TM. Physicians should only claim credit commensurate with the extent of their participation in the activity. Verification of Attendance Verification of attendance will be provided to all professionals. Special Needs is in full compliance with provisions of the Americans with Disabilities Act (ADA) and is accessible for individuals with special needs. If you require special accommodations please contact the Page and William Black Post-Graduate School of Medicine at Acknowledgment Supported by an educational grant from Onyx Pharmaceuticals, Inc.

3 The LIVER CANCER: MANAGEMENT AND CHALLENGES GENERAL MEETING Hatch Auditorium, Guggenheim Pavilion, 2nd Floor 1468 Madison Avenue at 100th Street New York, NY 8:30-9:00 am Registration 9:00-9:10 am Welcome and Opening Steven Burakoff, MD, Director, Tisch Cancer Institute 9:10-9:30 am Achievements of Josep M. Llovet, MD, 9:30-10:15 am Hans Popper Lecture: Hans Popper s Perspective Presentation: Josep M. Llovet, MD Resection and transplantation in HCC: where are we going? Vincenzo Mazzaferro, MD, Istituto Nationale di Tumori, Milan 10:15-10:30 am Coffee Break 10:30-12:00 pm PREVENTION, STAGING AND LOCAL TREATMENT OF HCC Chairman: Myron Schwartz, MD 10:30-10:50 am Impact of novel anti-viral therapies in the development of HCC Douglas Dieterich, MD 10:50-11:10 am Overview of staging systems and treatment strategies in HCC Morris Sherman, MD, Toronto General Hospital, Toronto, Canada 11:10-11:30 am Surgical Resection: Results from ISMMS and international surveys Sasan Roayaie, MD, 11:30-11:50 pm Indications of loco-regional therapies in liver cancer Laura Kulik, MD, Northwestern University, Chicago, Illinois

4 ! 11:50-12:30 pm Lunch 12:30-2:00 pm MANAGEMENT OF ADVANCED LIVER CANCER: Chairman: Josep M Llovet, MD 12:30-1:00 pm Challenges in systemic management: why Phase III studies are failing? Josep M Llovet, MD, 1:00-1:30 pm Emerging therapies in phase I/II Charissa Chang, MD, 1:30-2:00 pm Assessment of response in HCC: mrecist vs RECIST Riccardo Lencioni, MD, PhD Pisa University Hospital, Pisa, Italy 2:00-2:20 am Coffee Break 2:20-4:00 pm NOVEL DRIVERS OF HEPATOCARCINOGENESIS Chairman: Samuel Waxman, MD 2:20-2:40 pm What do we know about chemopreventive targets in HCC Yujin Hoshida, MD, PhD, 2:40-3:00 pm Genome sequencing in HCC and ICC: novel targets Ke Hao, PhD, Genomic Institute 3:00-3:20 pm Methylation-based classification and prognosis prediction in HCC Augusto Villanueva, MD BCLC-Group IDIBAPS. Barcelona, Spain 3:20-3:40 pm Are mirna druggable in oncology? Sara Toffanin, PhD, 3:40-4:00 pm Current knowledge of pathogenesis of intrahepatic cholangiocarcinoma Daniela Sia, PhD, 4:00 pm Closing Remarks/Adjournment Josep M Llovet, MD, SCHEDULE IS SUBJECT TO CHANGE Faculty Disclosure It is the policy of Icahn School of Medicine at Mount Sinai to ensure objectivity, balance, independence, transparency, and scientific rigor in all CME-sponsored educational activities. All faculty participating in the planning or implementation of a sponsored activity are expected to disclose to the audience any relevant financial relationships and to assist in resolving any conflict of interest that may arise from the relationship. Presenters must also make a meaningful disclosure to the audience of their discussions of unlabeled or unapproved drugs or devices. This information will be available as part of the course material.

5 The LIVER CANCER: MANAGEMENT AND CHALLENGES Name Address First MI Last Degree (MD, DO, etc.) City State Country Zip Tel Fax * Institution/Affiliation *Confirmation will be sent via Registration Fee Complimentary Register On-line at: Please scan this code with your smartphone to go to the program website with registration link. Cancellation Policy All cancellations must be confirmed in writing to The Page and William Black Post-Graduate School by February 1, No refunds will be made after that date for cancellations or no shows. For conference information, please call the Office of CME at or

6 The Icahn School of Medicine at Mount Sinai The Page and William Black Post-Graduate School One Gustave L. Levy Place Box 1193 New York, NY The LIVER CANCER: MANAGEMENT AND CHALLENGES Free conference Registration required go to:

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