CURRICULUM VITAE. Brynie Slome Collins, M.D. Department of Gastroenterology and Nutrition 4650 Sunset Blvd MS 78 Los Angeles, Ca 90027

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1 A. PERSONAL INFORMATION CURRICULUM VITAE Name in Full Business Address Brynie Slome Collins, M.D. Department of Gastroenterology and Nutrition 4650 Sunset Blvd MS 78 Los Angeles, Ca Business Phone (323) Place of Birth Citizenship Address Cape Town, South Africa U.S.A. B. EDUCATION High School Harvard-Westlake High School, LA, CA, 1993 University University of California at Berkeley, Berkeley, Ca, B.A. (Psychology) cum laude, 1997 St. Catherine s College, University of Oxford, Oxford, England Medical School Internship Residencies Fellowship Albert Einstein College of Medicine, Bronx, NY. M.D., 2001 UCLA Mattel Children s Hospital, LA, CA, July 2001-June 2002, Pediatrics UCLA Mattel Children s Hospital, LA, CA, July 2002-June 2004, Pediatrics Childrens Hospital Los Angeles, USC Keck School of Medicine, Gastroenterology, Hepatology and Nutrition, LA, CA, July 2005-June 2008 Honors and Awards Alpha Omega Alpha Honor Society, 2001 Annual Janet M. Glasgow Achievement Award given by American Medical Women s Association, Inc.,

2 Licensure California, 2002 (Medical License #A80600) DEA #BS Board Certification Diplomat, American Board of Pediatrics, 2004 Diplomat, American Board of Pediatrics- Sub-Board of Pediatric Gastroenterology, 2010 C. PROFESSIONAL BACKGROUND Previous Employment Pediatrician in Private Practice, Valencia Pediatrics Association, Academic Appointments Assistant Professor of Pediatrics, USC Keck School of Medicine, LA, CA 2008-present Hospital Appointments Attending Staff Physician, Department of Pediatrics, Providence Tarzana Medical Center, Tarzana, California present Attending Staff Physician, Miller Children s Hospital, Long Beach, California, 2010-present Attending Staff Physician, Department of Pediatrics, Division of Gastroenterolgy and Nutrition, Childrens Hospital Los Angeles, LA, CA, 2008-present Attending Staff Physician, Department of Pediatrics, Henry Mayo Newhall Memorial Hospital, Valencia, California, Attending Staff Physician, Department of Pediatrics, Los Angeles County- Olive View-UCLA Medical Center, Sylmar, California, Teaching Responsibilities Miller Children s GI Ward Service Miller Children s Hospital, CHLA Pediatric GI Ward Service Childrens Hospital Los Angeles, 2008-present CHLA Monthly House-staff Attending Rounds Lecturer Childrens Hospital Los Angeles, 2007-present 2

3 USC Keck School of Medicine Monthly Pediatric Nutrition Course Lecturer Childrens Hospital Los Angeles, UCLA Dentistry School Pediatric Subspecialty Course Lecturer UCLA, 2004 UCLA Continuity Clinic Resident Lecturer UCLA Olive View Medical Center Resident Lecturer Olive View Medical Center, John F. Kennedy High School Educational Project Creator Albert Einstein College of Medicine, 1999 Administrative responsibilities Pediatric GI Fellowship Committee Member Childrens Hospital Los Angeles, 2006-present Accreditation Committee for Graduate Medical Education Member Childrens Hospital Los Angeles, 2005-present Madisons Foundation Research Committee Member UCLA, Pediatric Residency Reach Out and Read Fundraising Committee UCLA Medical Center Ethics Committee Alternate Member UCLA, Violence Symposium Committee Member Albert Einstein College of Medicine, D. SOCIETY MEMBERSHIPS Distinguished Alpha Omega Alpha Honor Society, 2001-present 3

4 National American Gastroenterological Association, 2005-present American Academy of Pediatrics, 2001-present American Medical Association, 1997-present Medical Student Steering Committee member, Attended national conferences in Hawaii (98) and Chicago (99) International North American Society of Pediatric Gastroenterology, Hepatology and Nutrition, 2005-present Fellow s Committee member, E. SERVICE Journal Reviews Digestive Diseases and Sciences, Journal of Pediatric Gastroenterology and Nutrition, Grant Reviews The Netherlands Organization for Health Research and Development, 2010 F. RESEARCH ACTIVITIES Major Areas of Research Interest The role of small intestinal bacterial overgrowth in children with GI diseases Host-gut microbial interactions GI diseases in children with Autism Research in Progress A Non-Interventional Long-term Post-Marketing Registry of Patients Treated with Certolizumab Pegol (Cimzia ) for Crohn's Disease. Co- Investigator, CHLA CCI (APP ), 2010-present 4

5 The role of MET receptor signaling abnormalities associated with cooccurring gastrointestinal disorders in autism spectrum disorder. Co-Investigator, CHLA CCI (CCI ) approved study, 2009-present An Open Label Pilot Study Evaluating the Safety and Evidence of Therapeutic Effect of a 96-Hour Continuous Intravenous Administration of 2-0, 3-0 Desulfated Heparin (ODSH) for the Treatment of Exacerbation of Protein Losing Enteropathy (PLE) Associated With Single Ventricle Palliative Surgery Co-investigator, CHLA CCI (CCI ), approved study, 2010-present Research Grants R21 HD , Title The MET Signaling System, Autism and Gastrointestinal Dysfunction Role: Co-Investigator The Saban Research Institute Jr. Faculty Clinical Research Academic Career Development Award, Amount awarded, 50% salary support Role: Principal Investigator The Saban Research Institute Research Career Development Award, Amount awarded, $40,000 Role: Principal Investigator G. Invited Lectures Gut Flora in Health and Disease, The Saban Research Institute, Los Angeles, California, 10/20/2009 Chronic abdominal pain and small intestinal bacterial overgrowth, CHLA division of pain management, 1/16/2010 Chronic abdominal pain and small intestinal bacterial overgrowth, for Updates in Pediatrics, Bakersfield Memorial Hospital 4/10/2010 5

6 H. Bibliography Peer Reviewed 1. Gardner FEM, Burton J, Slome B and Simpson H. Psychological effects of limb deformities in children. Proceedings of the British Psychological Society 1997; 5: Bahar RJ, Collins BS, Steinmetz B and Ament M. Double-blind placebo-controlled trial of amitriptyline for the treatment of irritable bowel syndrome in adolescents. J Pediatr. 2008; 152: Collins, BS and Lin HC. Chronic abdominal pain in children is associated with high prevalence of abnormal microbial fermentation. Dig Dis Sci. 2010; 55(1): Collins, BS and Lin HC. Double-blind placebo controlled antibiotic treatment study of small intestinal bacterial overgrowth in children with chronic abdominal pain. JPGN, 2011; 52(4): Invited Articles and Chapters 1. Collins BS and Thomas DW. Chronic Abdominal Pain. Pediatr Rev, 28: , 2007 Abstracts 1. Collins BS and Naon H. Is there a greater prevalence of disaccharidase deficiency in pediatric patients with graft versus host disease? Gastrointestinal Endoscopy, 63(5) A-314, Collins BS, Taschereau EO and Lin HC. Regional differences in hydrogen sulfide content. Neurogastroenterol Motil, 19(5) A-36, Bahar RJ, Collins BS, Steinmetz B and Ament M. Double-blind placebo-controlled trial of amitriptyline for the treatment of irritable bowel syndrome in adolescents. Gastroenterology, 132 (4) A-520, Collins, BS, Lin HC. Double-blind placebo controlled trial of xifaxan for the treatment of small intestinal bacterial overgrowth in children with chronic abdominal pain. Gastroenterology, 138(5), Supplement 1: S-356,

7 Presentations 1. Slavin S, Slome B, Smith M and O Gara E, Giving Bad News: Developing and Implementing an Educational Seminar for Pediatric Trainees, An Educational Workshop. Presented at the Annual Meeting of the Pediatric Academic Society. San Francisco, California, May Collins, BS and Naon H. Is there a greater prevalence of disaccharidase deficiency in pediatric patients with graft versus host disease? Presented at Digestive Disease Week and the 107 th Annual Meeting of the American Gastroenterological Association. Los Angeles, California, May Collins BS, Taschereau EO and Lin HC. Regional differences in hydrogen sulfide content. Presented at the American Motility Society Meeting. Grand Bahamas, March Bahar RJ, Collins BS, Steinmetz B and Ament M. Double-blind placebo-controlled trial of amitriptyline for the treatment of irritable bowel syndrome in adolescents. Presented at Digestive Disease Week and the 108 th Annual Meeting of the American Gastroenterological Association. Washington D.C, May Bahar RJ, Collins BS, Steinmetz B and Ament M. Double-blind placebo-controlled trial of amitriptyline for the treatment of irritable bowel syndrome in adolescents. Presented at the New Insights into Childhood Functional Abdominal Pain and IBS. A multidisciplinary approach symposium at the Annual Meeting of the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition. Salt Lake City, October Collins, BS, Lin HC. Double-blind placebo controlled trial of xifaxan for the treatment of small intestinal bacterial overgrowth in children with chronic abdominal pain. Presented at Digestive Disease Week and the 111 th Annual Meeting of the American Gastroenterological Association. New Orleans, May

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