Women's Postpartum Sexual Health Program: A Collaborative and Integrated Approach to Restoring Sexual Health in the Postpartum Period

Size: px
Start display at page:

Download "Women's Postpartum Sexual Health Program: A Collaborative and Integrated Approach to Restoring Sexual Health in the Postpartum Period"

Transcription

1 Journal of Sex & Marital Therapy ISSN: X (Print) (Online) Journal homepage: Women's Postpartum Sexual Health Program: A Collaborative and Integrated Approach to Restoring Sexual Health in the Postpartum Period Hillary Lianna McBride, Sarah Olson, Janelle Kwee, Carolin Klein & Kelly Smith To cite this article: Hillary Lianna McBride, Sarah Olson, Janelle Kwee, Carolin Klein & Kelly Smith (2016): Women's Postpartum Sexual Health Program: A Collaborative and Integrated Approach to Restoring Sexual Health in the Postpartum Period, Journal of Sex & Marital Therapy To link to this article: Accepted author version posted online: 22 Jan Submit your article to this journal Article views: 45 View related articles View Crossmark data Full Terms & Conditions of access and use can be found at Download by: [University of California, San Diego] Date: 18 March 2016, At: 11:46

2 POSTPARTUM SEXUAL HEALTH PROGRAM Women s Postpartum Sexual Health Program: A Collaborative and Integrated Approach to Restoring Sexual Health in the Postpartum Period Hillary Lianna McBride Masters 1,*, Sarah Olson 2, Janelle Kwee 3, Carolin Klein 4, Kelly Smith 5 1 University of British Columbia, Educational and Counselling Psychology, Vancouver Campus, 2125 Main Mall, Vancouver, British Columbia, V6T 1Z4 Canada 2 South Hill Family Health Centre, Vancouver, British Columbia, Canada olson.se@gmail.com 3 Trinity Western University, Langley, British Columbia, Canada drjanellekwee@gmail.com 4 Vancouver General Hospital, Vancouver, British Columbia, V5Z 1L5 Canada Carolin.Klein@vch.ca 5 University of British Columbia, Vancouver, British Columbia, Canada smithkellybrook@gmail.com * Corresponding Author hillarylmcbride@gmail.com Abstract The postpartum period presents unique challenges to couples' relationships and sexuality, yet these factors are often left unaddressed by health care providers. The Women s Postpartum Sexual Health Program (WPSHP), a four session group- and couples-based program delivered by 1

3 an interdisciplinary care team at a family practice centre, was designed specifically to address common concerns among postpartum women and their partners. The interrelated, biopsychosocial aspects of women s sexuality in the postpartum period are summarized, followed by a detailed description of the WPSHP content and structure. This information is intended to serve as a practical resource for implementation and adaptation of the WPSHP across different practice settings. KEYWORDS postpartum; sexual health; sexual function; biopsychosocial; intervention 2

4 The postpartum period is a time of great transition for parents, who are learning, either for the first time or again, how to adjust their lives to care for their new infant. While this can be a time of joy and intimacy, it can also be rife with challenges (Collier, 2010). Parents are tasked with negotiating new priorities in life which can be at odds with spending quality time together as a couple (Alves & Vieira, 2008; Demyttenaere, Gheldof, & Van Assche, 1995). In addition to negotiating changes in the relationship, women also must adjust to how their postpartum bodies look and function differently than they did before childbirth. Sleep deprivation, hormonal changes following childbirth and as a result of breastfeeding, and potentially painful and/or prolonged recovery from a vaginal or Cesarean delivery can all impact physical as well as emotional health. These factors come together to make the postpartum period a time when many couples struggle to have a healthy, regular, and enjoyable sex life (Alves & Vieira, 2008). In one study investigating postpartum sexual activity, 83% of 484 participants reported sexual challenges within the first three months of giving birth, and dyspareunia resulting from vaginal dryness was a primary concern (Barrett et al., 2000). Health care providers often neglect discussing postpartum sexuality with patients (Barrett et al., 2000). This can contribute to women s feelings of isolation, sadness, failure, and shame, and worries that there is something wrong with them (Johnson, 2011; Leeman & Rogers, 2012). Women s sexuality is complex and encompasses more than physiological and hormonal responses (Basson, 2000). While the literature speaks to hormonal and physical changes resulting from childbirth, there is a lack of data about psychosocial factors that contribute to women s postpartum sexual health concerns (Abdool, Thakar, & Sultan, 2009). Further, the existing 3

5 solutions to address these concerns are insufficient (Hipp, Kane Low, & Van Ander, 2012). Proposed solutions have generally been limited to the physical or biological domain; consequently, there is a need for interventions to incorporate the relational and psychological components of women s postpartum sexuality (Abdool, Thakar, & Sultan, 2009; Collier, 2010; Demyttenaere, Gheldof, & Van Assche, 1995; Leeman & Rogers, 2012). While providing care at the South Hill Family Health Centre, a family practice located in Vancouver, Canada, it became clear that better support for women navigating the unique challenges of postpartum sexuality was needed. South Hill Family Health Centre is unique in that it brings together an interdiscliplinary team, including family physicians, a nurse practitioner, dieticians, and a clinical counselor, who have experience with group medical care during pregnancy and postpartum and for well-baby visits. Given that the Centre grew out of a maternity care practice, postpartum women make up a large proportion of the patient population. These women frequently report struggling with sexual concerns, including significantly decreased or absent sexual desire and/or the presence of pain with penetration, and resulting negative impact (e.g., self-image, relationship satisfaction). In order to provide adequate care to women and partners, we created the Women s Postpartum Sexual Health Program (WPSHP), a multidimensional curriculum that includes group- and couple-based sessions. The purposes of this article are to summarize the biopsychosocial factors that can impact women s postpartum sexuality and informed the development of our program, and to describe the content and structure of the WPSHP. The WPSHP addresses the biological, psychological, and relational components of women s sexuality, and has been designed specifically to address the gap in treatments identified in the literature (Abdool, Thakar, & Sultan, 2009; Demyttenaere, Gheldof, 4

6 & Van Assche, 1995; Handa, 2006; Hipp, Kane Low, & Van Ander, 2012; Johnson, 2011). This information is intended to serve as a resource for implementation and adaptation of the WPSHP across different practice settings. Women s Sexuality The traditional understanding of human sexuality stems from the groundbreaking work of Masters and Johnson (1966), who suggested that the human sexual response cycle follows a linear model progressing through four phases: excitement (i.e., arousal), plateau, orgasm, and resolution. This model was subsequently expanded by Kaplan (1979) to include an initial sexual desire phase. While this model has been useful for understanding the sexual response cycle, it lacks important components that are important for understanding female sexual response (Basson, 2000). With the introduction of Basson s (2000) non-linear model of female sexual response, two essential components missing from Masters and Johnson s original conceptualization---emotional intimacy and relational dynamics---were added. These factors, as identified by Basson (2000), contribute to women s sexual desire, sexual motivation, and sexual response. Additionally, whereas Masters and Johnson s model implied that normal sexual desire is spontaneous, Basson s (2000) model highlights that sexual desire in long-term relationships is more often responsive than spontaneous (Basson, 2000). It has been argued that acceptance of the original Master s and Johnson model has led to clinical and societal misunderstandings about female sexuality, resulting in a tendency for overdiagnosis of sexual disorders in women (Basson, 2000, 2005). Further, women who compare themselves to the original model may feel shame due to a lack of spontaneous desire to engage in 5

7 sexual behavior. Basson s model has implications for understanding and providing care to women who report sexual concerns such as low desire. Specifically, there is a need for recognition that women s sexual response more commonly stems from intimacy needs rather than a need for physical sexual arousal (Basson, 2000, p. 51). This information can normalize women s experiences and reframe what is often thought of as low sex-drive. This process is particularly important as, when women feel shame, low self-worth, or guilt for not desiring sexual activity with their partner as they believe they should, their ability to desire and engage in sexual behavior freely is further diminshed (Basson, 2005). Considering the role emotional intimacy has in women s sexuality, it is important that psychological and relational factors be a central focus of treatment for postpartum women s sexual concerns. Hormonal and Physical Changes in the Postpartum Period Significant neuroendocrine changes occur postpartum that can contribute to decreased sexual interest during the first six to 12 months following childbirth (Rupp et al., 2013; LaMarre et al, 2003). Some of these changes likely occur within the amygdala, which is related to both sex drive and emotion and rewards processing, and postpartum women have been shown to exhibit decreased amygdala responsiveness (Rupp et al, 2013). Elevated prolactin and oxytocin levels associated with breastfeeding can also be associated with low sexual desire in postpartum women (LaMarre et al, 2003). (Altemus, 1995; Carter et al., 2007; Rupp et al., 2013). Finally, breastfeeding can lead to postpartum dyspareunia, as high levels of prolactin and low levels of estrogen often cause changes including decreased vaginal lubrication (Johnson, 2011; Barrett, 2000). 6

8 Several potential complications resulting from pregnancy and delivery can also make resuming regular sexual activity more difficult and/or less desirable. These complications include perineal pain, vaginal or uterine prolapse, and weakened pelvic floor muscles. While perineal pain due to trauma is associated almost exclusively with vaginal deliveries, the latter two issues also arise among women who have had Cesarean deliveries (Abdool, Thakar, & Sultan, 2009; Acele & Karaçam, 2012; Alves & Vieira, 2008; Phillips & Monga, 2004). Phillips and Monga (2004) reported that perineal trauma affects up to 85% of women following a vaginal delivery, and this risk is increased by the use of forceps, episiotomy and certain methods of perineal repair. Women with pre-existing genital pain are at increased risk of worsening pain symptoms following delivery (Nguyen et al, 2012). Although the percent of women who have sexual challenges post-natally is high, only 15% of women report discussing them with their health care providers (Barrett et al., 2000). Studies have found that, in spite of biological contributors for sexual challenges and the frequency with which they are experienced in the postpartum period, women feel uncomfortable bringing up these issues with their care providers, and care providers feel unsure about how to address the issues within routine visits (Abdool, Thakar, & Sultan, 2009; Barrett et al., 2000; Jha & Thakar, 2010; Johnson, 2011). In addition to lack of sleep and the stress of caring for a newborn, these physical and hormonal factors can contribute to sexual challenges. Further, these factors can affect and be affected by psychosocial challenges in the postpartum period, highlighting the important interplay between a woman s biology and her psychosocial functioning. 7

9 Psychosocial Contributors to Postpartum Sexual Concerns Sexual satisfaction and functioning are highly influenced by psychological factors, including stress, mood, anxiety, sense of self/self-esteem, body image, past traumatic experiences and general well-being (Altho & Needle, 2013; Mickelson & Joseph 2012). Although it is unknown which occurred first, Basson (2005) found high correlations between women s low sexual desire and low mood, low self-esteem, and anxiety or worry. As well, negative life experiences, and how they are handled, can contribute to or predict sexual difficulties (Althof & Needle, 2013). Even when mental health issues do not occur at a clinical threshold, routine hassles from daily life are sufficient to create distraction and distress that can impair, for example, a woman s sexual desire (Basson, 2005; Carvalho & Nobre, 2010). The postpartum period can present specific psychological challenges. New mothers have been found to experience psychosocial difficulties, such as isolation, role and identity challenges, and anxiety. Up to 85% of these women report baby blues and approximately 20% meet diagnostic criteria for postpartum depression (Bueno, 2010; Zers, Washke, & Ehler, 2008). Leeman and Rogers (2012) reported that 40% of women with depression report challenges with sexual desire, arousal and orgasm, and that depression, specifically, has been found to be associated with low sexual desire and low rates of intercourse at weeks postpartum. Even without the experience of acute mental health issues, adjusting to a new baby is challenging due to factors such as fatigue, increased responsibilities and housework, stress resulting from decreased finances, and/or poor self-image related to increased weight gain (Alhof & Needle, 8

10 2013; Basson, 2000; Collier, 2010; Demyttenaere, Gheldof, & Van Assche, 1995; Hipp, Kane Low, & Van Anders, 2012; Mickelson & Joseph, 2012; Petch & Halford, 2008). Relational Factors As highlighted by Basson (2000, 2001, 2005), relational components play an important role in women s sexuality. Emotional intimacy can enhances sexual satisfaction, which in turn further increases emotional intimacy, creating a positive cycle of physical and relational closeness (Basson, 2001; Leiblum, 1998; Tiefer, 1991). This is particularly true for the women for whom sexual desire is largely responsive as opposed to spontaneous. A woman s desire to engage sexually with her partner is influenced by how desired, attractive, and appreciated she feels in her relationship (Basson, 2005). Likewise, sexual desire is negatively influenced by feelings of guilt about not satisfying a partner, as well as lack of emotional safety, tenderness or respect (Basson, 2001). Due to the significant relational changes that can occur after having a baby, many couples experience decreased relationship satisfaction associated with their sexual relationship (Petch & Halford, 2008). Issues with privacy and conflicting schedules also affects couples' relationship and sexual intimacy (Althof & Needle, 2013). There is even evidence that a women s perception of their partner s sexuality have more influence on postpartum sexuality than do physical factors (Hipp, Kane Low, & Van Anders, 2012). There is a clear link between sexual difficulties in women and couples' relationship challenges, including having an unsatisfactory relationship or experiencing ongoing relationship challenges; however, the direction of causality is not always clear (Althof & Needle, 2013). 9

11 Moreover, when relationship and sexual difficulties are treated as interrelated, treatment yields significantly improved results compared to when these issues are addressed separately (Althof & Needle, 2013; Basson, 2001; Johnson, 2011). Relationship skill-building, including psychoeducation about sexuality, practicing supportive and encouraging behaviors, and improving conflict management skills, has been shown to assist couples in their transition to parenthood, ultimately leading to increased relationship and sexual satisfaction (Petch & Halford, 2008). Women s Postpartum Sexual Health Program (WPSHP) In light of the above review, which outlines the need for integrated solutions to address women s postpartum sexual health concerns, the WPSHP was created. The WPSHP provides support for and focuses on addressing the multidimensional aspects of women s postpartum sexual concerns. Although the program aims to address the complex nature of women s postpartum sexuality, it is not designed to comprehensively treat pain, low desire, other sexual concerns, or ongoing relational conflicts. Instead, the WPSHP is meant to provide psychoeducation, an introduction to skills and interventions that can enhance sexual and relationship satisfaction, and group support, offering a safe space for participants to obtain information and discuss the challenges of postpartum sexuality with other women. Participants are encouraged to try the various introduced skills in order to determine which may best suit their individual and relational needs. Continued skills practice is encouraged upon completion of the group, including through additional support via individual or couples sex and relationship therapy. WPSHP Structure 10

12 The WPSHP is designed for adult women in the postpartum period who are in a committed relationship and who are experiencing subjective sexual concerns following the birth of their child(ren). We have defined the postpartum period as the first year following childbirth. The WPSHP is designed to occur over approximately eight weeks in two-week intervals, for a total of four sessions. There is, however, room for flexibility, and it is possible for therapeutic interventions to occur three to four weeks apart, as long as program continuity and commitment can be maintained. The first three sessions are conducted in a group format, with each session lasting 120 minutes. Groups range in size from six to twelve women, with eight being an ideal number that is small enough to promote a sense of connection between group members yet large enough to demonstrate that participants are not alone in their experiences. The fourth session is a 90-minute couple s session. The structure of each session includes, home activities review, introduction of a new topic and/or skill, discussion, and homework. Homework is designed to provide continuity between sessions, help participants to further consider and retain information provided in session, and give strategies and techniques to begin addressing factors that are negatively impacting sexual intimacy and well-being. Group sessions are facilitated by one or more clinicians who have a background in women s sexual and post-natal health and who have experience facilitating groups and presenting material of a sensitive nature. These facilitators may include gynecologists, obstetricians, family doctors, nurses, nurse practitioners, social workers, or psychologists/counselors. A co-facilitator is also present to provide continuity and additional 11

13 group support. The couple s session is facilitated by a social worker, psychologist, or counselor with experience helping couples navigate sexual and relationship concerns. To enhance participants' abilities to concentrate on the session content, as well as to provide a break from parenting, participants attend sessions without their children. This childfree attendance also affirms women s identities as not only mothers, but also as individuals and partners who are multidimensional sexual beings. To facilitate attendance, on-site childcare is provided. The session-by-session content of the Women s Postpartum Sexual Health Program is summarized in Table 1 1. Conclusion This WPSHP was designed to aid women and their partners struggling with postpartum sexual concerns using multidisciplinary service delivery. This program introduces women and couples to a range of topics and skills to help address such concerns. Our intent in sharing the structure and content of the program is to provide a practical resource for implementation and adaptation of the WPSHP across different practice settings. Qualitative and quantitative evaluation research is currently underway to examine the effectiveness of the WPSHP and to guide refinement of the program if needed. 1 Readers interested in materials used during the WPSHP may contact the corresponding author directly. 12

14 References Abdool, Z., Thakar, R., & Sultan, A. H. (2009). Postpartum female sexual function. European Journal of Obstetrics & Gynecology and Reproductive Biology, 145(2), doi: /j.ejogrb Acele, E. Ö., & Karaçam, Z. (2012). Sexual problems in women during the first postpartum year and related conditions. Journal of Clinical Nursing, 21(7 8), doi: /j x Altemus, M.(1995). Neuropeptides in anxiety disorders: Effects of lactation. Annals of the New York Academy of Science, 771, Althof, S. E., & Needle, R. B. (2013). Psychological and interpersonal dimensions of sexual function and dysfunction in women: An update. Arab Journal of Urology, 11(3), doi: /j.aju Alves, M. & Vieira, R. (2008). Facts that influence the feminine sexuality after childbirth. Sexologies, 17, Barrett, G., Pendry, E., Peacock, J., Victor, C., Thakar, R., & Manyonda, I. (2000). Women s sexual health after childbirth. BJOG: An International Journal of Obstetrics & Gynaecology, 107(2), doi: /j tb11689.x Basson, R. (2000). The female sexual response: A different model. Journal of Sex &Marital Therapy, 26(1), doi: /

15 Basson, R. (2001). Using a different model for female sexual response to address women s problematic low sexual desire. Journal of Sex & Marital Therapy, 27(5), doi: / Basson, R. (2005). Women s sexual dysfunction: Revised and expanded definitions. Canadian Medical Association Journal, 172(10), doi: /cmaj Basson, R., Brotto, L. A., Carlson, M., Driscoll, M., Grabovac, A., & Smith, K. B. (2012). Moving on with our sexual lives despite painful penetration from provoked vestibulodynia and pelvic muscle tension: A mindfulness-based approach. Unpublished manuscript. Beck, A. T. (1979). Cognitive therapies and the emotional disorders. New York, NY: Penguin Books. Burns, D. (1980). Feeling good: The new mood therapy. New York, NY: Harper Collins. Bueno, J. (2010). Life after birth. Therapy Today, 21(4), Carter, C.S., Pournajafi-Nazarloo, H., Kramer, K.M., Ziegler, T.E., White-Traut, R., Bello, D., & Schwertz, D. (2007). Oxytocin: Behavioral associations and potential as a salivary biomarker. Annals of the New York Academy of Science, 1098, Carvalho, J., & Nobre, P. (2010). Predictors of women s sexual desire: The role of psychopathology, cognitive-emotional determinants, relationship dimensions, and medical factors. Journal of Sexual Medicine, 7, Collier, F. (2010). When a couple wants a baby: What are the consequences on their sexuality?. Sexologies, 19(3), doi: /j.sexol

16 Demyttenaere, K., Gheldof, M., & Van Assche, F. A. (1995). Sexuality in the postpartum period: A review. Current Obstetrics & Gynaecology, 5(2), Handa, V. L. (2006). Sexual function and childbirth. Seminars in Perinatology, 30(5), doi: /j.semperi Hipp, L. E., Kane Low, L., & van Anders, S. M. (2012). Exploring women s postpartum sexuality: Social, psychological, relational, and birth related contextual Factors. The Journal of Sexual Medicine, 9(9), doi: /j x Jha, S., & Thakar, R. (2010). Female sexual dysfunction. European Journal of Obstetrics & Gynecology and Reproductive Biology, 153(2), doi: /j.ejogrb Johnson, C. E. (2011). Sexual health during pregnancy and the postpartum (CME). The Journal of Sexual Medicine, 8(5), doi: /j x Leeman, L. M. & Rogers, R.G. (2012). Sex after childbirth: Postpartum sexual function. Obstetrics and Gynecology, 119(3), doi: /AOG.0b013e Leiblum, S.R. (2000). Redefining female sexual response. Contemporary Obstetrics and Gynecology, 45(11), Masters, W. H., & Johnson, V. E. (1966). Human sexual response. Boston, MA: Little, Brown. Masters, W. H., & Johnson, V. E. (1970). Human sexual inadequacy. London, Churchill. Mickelson, K. D. & Joseph, J.A. (2012). Postpartum body satisfaction and intimacy in first-time parents. Sex Roles, 67, doi: /s

17 Nguyen, R. H., Stewart, E. G., & Harlow, B. L. (2012). A population-based study of pregnancy and delivery characteristics among women with vulvodynia. Pain and Therapy, 1(1), Petch, J. & Halford, W.K. (2008). Psycho-education to enhance couples' transition to parenthood. Clinical Psychology Review, 28, doi: /j.cpr Phillips, C. & Monga, A. (2004). Childbirth and the pelvic floor: The gynaecological consequences. Reviews in Gynaecological Practice, 5, doi: /j.rigp Rupp, H. A., James, T. W., Ketterson, E. D., Sengelaub, D. R., Ditzen, B., & Heiman, J. R. (2013). Lower sexual interest in postpartum women: Relationship to amygdala activation and intranasal oxytocin. Hormones and Behavior, 63(1), doi: /j.yhbeh Tiefer, L. (1991). Historical, scientific, clinical and feminist criticisms of the human sexual response cycle. Annual Review of Sex Research, 2, Weiner, L. & Avery-Clark, C. (2014). Sensate Focus: Clarifying the Masters and Johnson s model. Sexual and Relationship Therapy, 29 (3), doi: / Zaers, S., Waschke, M., & Ehlert, U. (2008). Depressive symptoms and symptoms of posttraumatic stress disorder in women after childbirth. Journal of Psychosomatic Obstetrics and Gynaecology, 29(1), doi: /

18 Table 1 Women s Postpartum Sexual Health Program Session Content Summary Session 1: Female Sexual Response and the Postpartum Period The first WPSHP session is designed to introduce women to the group, normalize their postpartum experiences by reviewing the many reasons sexual intimacy can be compromised in the postpartum period, and introduce Basson s (2000) model of female sexual response. The goal of the latter is to increase understanding and to shift women s postpartum expectations of themselves and their sexual relationship. Welcome and Introduction Participants are introduced to the program, to each other, and to (15 minutes) the facilitators. Barriers to Sexual Intimacy During the first session, the facilitator asks participants to list in the Postpartum Period potential contributors to postpartum struggles with sexual (20 minutes) intimacy. Participants are also asked to try to classify each contributing factor as biological (i.e., physical or hormonal), psychological, relational, or some combination of each. The purpose of this exercise is to help women better understand the myriad of ways that the postpartum period can present challenges to sexual intimacy, as well as the difficulties with trying to classify factors as biological, psychological, or relational given their complex and interrelated nature. 17

19 Basson s (2000) Non- Linear Model of Female Sexual Response (50 minutes) Women are first introduced to Masters and Johnson s (1966) linear model of sexual response. Next, Basson s (2000) nonlinear model, in which sexual desire is acknowledged as more often being responsive than spontaneous and as highly impacted In-Session Reflection (15 minutes) by intimacy and relational factors, is presented. In discussing Basson s (2000) model, participants are provided with examples of how the factors identified in the previous section can interfere at each stage of the model and the complexity of women s sexuality is highlighted. Providing participants with normalizing information about female sexual response can lead to a profound realization about how their (and their partner s) prior beliefs and understanding of sexuality have negatively impacted feelings about themselves and their relationship. In line with Basson s (2000) model, participants are asked to consider and write down reasons that motivate them to be sexually intimate with their partners. Participants are also asked to consider factors that de-motivate or deter them from being sexually intimate with their partners. Finally, participants are asked reflect on where in the model they believe they and their partners experience the most difficulty. 18

20 Homework and wrap-up (20 minutes) Session 2: Addressing Biopsychosocial Factors that Impede Postpartum Sexuality Session 2 is designed to provide psychoeducation and strategies to begin addressing common biopsychosocial impediments to women s sexual relationship. Home Activities Review (15 minutes) Biological Changes in the Postpartum Period (30 minutes) Session 2 begins with psycho-education about how and why hormones fluctuate after childbirth. This includes information on how hormones related to breastfeeding can affect arousal and contribute to vaginal dryness which, in turn, can result in decreased subjective sexual arousal and pleasure. Women are given information on birth-related perineal injury and healing, and those who have concerns about their healing or who are experiencing ongoing pain are encouraged to book a visit with their primary care provider. In addition, information on postpartum dyspareunia is provided. Potential solutions, including lubricants and/or topical estrogen cream for vaginal dryness, and pelvic floor physiotherapy for some causes of dyspareunia, are briefly discussed. Importantly, the complexity 19

21 of women s sexual response is highlighted, as is the need for integrated solutions that go beyond pharmacological approaches and addressing psychosocial contributors to sexual concerns. The Role of Thoughts and Behaviours (40 minutes) To begin addressing the psychosocial contributors to sexual concerns, participants are provided an overview of how thoughts and feelings affect sexual functioning, sexual satisfaction, and intimacy, including an introduction to the ABC s of Rational Emotive Behavioral Therapy or Cognitive Behavioral Therapy. This includes a description of a cognitive snowball (Basson, et al, 2012). Participants are provided with a worksheet to then begin identifying their own snowball of underlying beliefs and emotional consequences, and the impact these have on their behaviors. Participants are also introduced to common cognitive distortions (Beck, 1979; Burns, 1980). They are asked to consider which of these they experience most frequently, both in general and as it relates to their sexual relationship, particularly the avoidance of sexual behavior or self-blame. The facilitator then demonstrates the strategy of cognitive restructuring, and, as practice, alternative thoughts are generated in the group. They are provided with a worksheet to practice identifying an event, the underlying belief(s), and the emotional consequence(s), 20

22 followed by possible alternative thoughts. Introduction to Sensate Focus (15 minutes) Participants are then introduced to sensate focus, designed to decrease anxiety and enhance awareness of pleasurable physical sensations during physical and sexual intimacy (see Weiner & Avery-Clark, 2014 for a description). This exercise is introduced to help couples begin to overcome avoidance and re-establish physical and, ultimately, sexual connection (Masters & Johnson, 1970). The facilitator normalizes that it can be difficult to resume sexual intimacy after a period of avoidance and/or disappointing or upsetting sexual experiences. Similarly, when resuming sexual activity, it can be difficult to remain in the 21

23 present moment, setting aside worries and negative expectations about the sexual experience or about how the baby is doing. Participants are oriented to the rationale and first stage of sensate focus (full-body touch, excluding breasts and genitals, where the giver touches the receiver according to the giver s own curiosity while receiving feedback from the receiver), and are encouraged to discuss and then practice this stage with their partners at least three times before the next session. The importance of scheduling time for this practice is emphasized, and detailed instructions are provided. Homework and wrap-up (20 minutes) Session 3: Intimacy and Effective Communication The final group session builds on previous material by focusing more specifically on intimacy. This session continues to orient participants to sensate focus, discusses the importance and principles of effective communication for both sexual and non-sexual topics, and discusses ways to maintain desire in long-term relationships. Home Activities Review (15 minutes) 22

24 Sensate Focus Continued (15 minutes) The remaining stages of sensate focus are described, including the rationale and potential benefits of each stage. Possible barriers are also briefly discussed and problem-solved. Participants are encouraged to consider discussing significant barriers to this exercise in their upcoming couple s session. Effective Communication (50 minutes) Maintaining Desire in Long-Term Relationships (20 minutes) Because many couples struggle to openly discuss sexual issues with one another, communication skills including active listening and I statements are introduced, as is the topic of emotional flooding and strategies to reduce such flooding during communication. Examples are provided and participants are given the opportunity to practice with a fellow group member. The facilitator provides information about the inverse relationship between comfort/routines and sexual desire, and the need to balance sexual and non-sexual routines with novelty. In addition, the importance of maintaining an atmosphere of romance in the relationship (e.g., continuing to make time together as a couple and to show affection on a regular basis) and possible aids for enhancing desire (e.g., erotic books) are highlighted. Homework and wrap-up 23

25 (20 minutes) Session 4: Couple s Session The purpose of the couple s session is to provide brief, personalized support to each participating woman and her partner. This support may involve answering questions from partners or questions that women did not feel comfortable asking in the group sessions, helping couples better understand relational issues that may be contributing to and/or resulting from sexual concerns, and/or providing additional recommendations and strategies to those discussed in the group sessions. Couples are encouraged to share their homework experiences from the group sessions, including areas of struggle. The session ends with inquiry regarding what women and partners have learned in the WPSHP, and what they believe they need to continue working on in their sexual relationship. Couples interested in pursuing further relationship and/or sex therapy are provided with a list of suitable resources, including contact information for local therapists. 24

26 本文献由 学霸图书馆 - 文献云下载 收集自网络, 仅供学习交流使用 学霸图书馆 ( 是一个 整合众多图书馆数据库资源, 提供一站式文献检索和下载服务 的 24 小时在线不限 IP 图书馆 图书馆致力于便利 促进学习与科研, 提供最强文献下载服务 图书馆导航 : 图书馆首页文献云下载图书馆入口外文数据库大全疑难文献辅助工具

Supporting Information. Electrochemiluminescence for Electric-Driven Antibacterial. Therapeutics

Supporting Information. Electrochemiluminescence for Electric-Driven Antibacterial. Therapeutics Supporting Information Electrochemiluminescence for Electric-Driven Antibacterial Therapeutics Shanshan Liu, a,b Huanxiang Yuan, a Haotian Bai, a Pengbo Zhang, a Fengting Lv, a Libing Liu, a Zhihui Dai,

More information

Racial disparities in the management of acne: evidence from the National Ambulatory Medical Care Survey,

Racial disparities in the management of acne: evidence from the National Ambulatory Medical Care Survey, Journal of Dermatological Treatment ISSN: 0954-6634 (Print) 1471-1753 (Online) Journal homepage: http://www.tandfonline.com/loi/ijdt20 Racial disparities in the management of acne: evidence from the National

More information

Optimization of Processing Parameters of Stabilizers After Enzymes Hydrolysis for Cloudy Ginkgo Juice

Optimization of Processing Parameters of Stabilizers After Enzymes Hydrolysis for Cloudy Ginkgo Juice Optimization of Processing Parameters of Stabilizers After Enzymes Hydrolysis for Cloudy Ginkgo Juice Haifeng Yu, Junyan Liu and Jingxi Yang 1 Introduction Ginkgo biloba, dating back 300 million years,

More information

Fetal Response to Intramuscular Epinephrine for Anaphylaxis during Maternal Penicillin Desensitization for Secondary Syphilis

Fetal Response to Intramuscular Epinephrine for Anaphylaxis during Maternal Penicillin Desensitization for Secondary Syphilis The Journal of Maternal-Fetal & Neonatal Medicine ISSN: 1476-7058 (Print) 1476-4954 (Online) Journal homepage: http://www.tandfonline.com/loi/ijmf20 Fetal Response to Intramuscular Epinephrine for Anaphylaxis

More information

Accepted Manuscript. Hemorrhagic cystitis associated with gefitinib treatment: a case report. Peng Zhang, Jinjing Tu, Tieding Chen, Rubing Li

Accepted Manuscript. Hemorrhagic cystitis associated with gefitinib treatment: a case report. Peng Zhang, Jinjing Tu, Tieding Chen, Rubing Li Accepted Manuscript Hemorrhagic cystitis associated with gefitinib treatment: a case report Peng Zhang, Jinjing Tu, Tieding Chen, Rubing Li PII: S0090-4295(18)30555-7 DOI: 10.1016/j.urology.2018.05.035

More information

Thinking & Reasoning Publication details, including instructions for authors and subscription information:

Thinking & Reasoning Publication details, including instructions for authors and subscription information: This article was downloaded by: [Umeå University Library] On: 07 October 2013, At: 11:46 Publisher: Routledge Informa Ltd Registered in England and Wales Registered Number: 1072954 Registered office: Mortimer

More information

Chapter 5 Trimalleolar Ankle Fracture: Posterior Plate for Posterior Malleolus Fractures

Chapter 5 Trimalleolar Ankle Fracture: Posterior Plate for Posterior Malleolus Fractures Chapter 5 Trimalleolar Ankle Fracture: Posterior Plate for Posterior Malleolus Fractures Roy I. Davidovitch and Alexander M. Crespo Introduction Trimalleolar ankle fractures with a posterior malleolus

More information

ACCEPTED ARTICLE PREVIEW. Accepted manuscript

ACCEPTED ARTICLE PREVIEW. Accepted manuscript First in Class Angiotensin Receptor Neprilysin Inhibitor in Heart Failure Orly Vardeny, PharmD, MS, Travis Tacheny, Scott D. Solomon, MD Cite this article as: Orly Vardeny, PharmD, MS, Travis Tacheny,

More information

Accepted Manuscript. Robotics in Orthopedics: A Brave New World. Brian S. Parsley, MD, Associate Professor

Accepted Manuscript. Robotics in Orthopedics: A Brave New World. Brian S. Parsley, MD, Associate Professor Accepted Manuscript Robotics in Orthopedics: A Brave New World Brian S. Parsley, MD, Associate Professor PII: S0883-5403(18)30163-3 DOI: 10.1016/j.arth.2018.02.032 Reference: YARTH 56428 To appear in:

More information

Effects of idebenone on electroencephalograms of patients with cerebrovascular disorders

Effects of idebenone on electroencephalograms of patients with cerebrovascular disorders Arch. Gerontol. Geriatr., 8 (1989) 355-366 355 Elsevier AGG 00266 Effects of idebenone on electroencephalograms of patients with cerebrovascular disorders Takashi Nakano a Matu6 Miyasaka a, Katsumi Mori

More information

SOME PRACTICAL IMPROVEMENTS IN THE CONTINUAL REASSESSMENT METHOD FOR PHASE I STUDIES

SOME PRACTICAL IMPROVEMENTS IN THE CONTINUAL REASSESSMENT METHOD FOR PHASE I STUDIES STATISTICS IN MEDICINE, VOL. 14, 1149-1161 (1995) SOME PRACTICAL IMPROVEMENTS IN THE CONTINUAL REASSESSMENT METHOD FOR PHASE I STUDIES STEVEN N. GOODMAN, MARIANNA L. ZAHURAK AND STEVEN PIANTADOSI Johns

More information

Journal of Chromatography A 819 (1998)

Journal of Chromatography A 819 (1998) Journal of Chromatography A 89 (998) 33 42 Investigation of potential degradation products of a newly synthesised b-lactam antibiotic by multi-stage liquid chromatography electrospray mass spectrometry

More information

Accepted Manuscript. Red yeast rice preparations: are they suitable substitutions for statins?

Accepted Manuscript. Red yeast rice preparations: are they suitable substitutions for statins? Accepted Manuscript Red yeast rice preparations: are they suitable substitutions for statins? Carlos A. Dujovne, MD, Fellow NLA, Certified Clinical Lipidologist PII: S0002-9343(17)30591-0 DOI: 10.1016/j.amjmed.2017.05.013

More information

How might treatment of ALK-positive non-small cell lung cancer change in the near future?

How might treatment of ALK-positive non-small cell lung cancer change in the near future? Expert Review of Anticancer Therapy ISSN: 1473-7140 (Print) 1744-8328 (Online) Journal homepage: http://www.tandfonline.com/loi/iery20 How might treatment of ALK-positive non-small cell lung cancer change

More information

Synthetic Tannins Structure by MALDI-TOF Mass Spectroscopy

Synthetic Tannins Structure by MALDI-TOF Mass Spectroscopy Synthetic Tannins Structure by MALDI-TOF Mass Spectroscopy S. Giovando, 1 A. Pizzi, 2 H. Pasch, 3,4 K. Rode 4 1 Centro Ricerche per la Chimica Fine Srl, S.Michele Mondovi, Italy 2 ENSTIB-LERMAB, Nancy

More information

uncorrected proof version

uncorrected proof version Galley Proof 8/02/2017; 9:17 File: jcm 1-jcm708.tex; BOKCTP/ljl p. 1 Journal of Computational Methods in Sciences and Engineering -1 (2017) 1 10 1 DOI 10.3233/JCM-170708 IOS Press 1 2 3 Comparison of sliding

More information

Indacaterol, a once-daily beta 2 -agonist, versus twice-daily beta-agonists or placebo for chronic obstructive pulmonary disease (Protocol)

Indacaterol, a once-daily beta 2 -agonist, versus twice-daily beta-agonists or placebo for chronic obstructive pulmonary disease (Protocol) Indacaterol, a once-daily beta 2 -agonist, versus twice-daily beta-agonists or placebo for chronic obstructive pulmonary disease (Protocol) Geake JB, Dabscheck EJ, Wood-Baker R This is a reprint of a Cochrane

More information

How Advertising Slogans

How Advertising Slogans How Advertising Slogans Can Prime Evaluations of Brand Extensions David M. Boush University of Oregon ABSTRACT Different versions of a brand slogan were presented to each of three treatment groups before

More information

Characterization of a prototype MR-compatible Delta4 QA-system in a 1.5 tesla MR-linac

Characterization of a prototype MR-compatible Delta4 QA-system in a 1.5 tesla MR-linac Physics in Medicine and Biology ACCEPTED MANUSCRIPT Characterization of a prototype MR-compatible Delta QA-system in a. tesla MR-linac To cite this article before publication: J H Wilfred de Vries et al

More information

Accepted Manuscript. Dural arteriovenous fistula between the inferolateral trunk and cavernous sinus draining to the ophthalmic vein: a case report

Accepted Manuscript. Dural arteriovenous fistula between the inferolateral trunk and cavernous sinus draining to the ophthalmic vein: a case report Accepted Manuscript Dural arteriovenous fistula between the inferolateral trunk and cavernous sinus draining to the ophthalmic vein: a case report Kan Xu, Kun Hou, Baofeng Xu, Yunbao Guo, Jinlu Yu PII:

More information

THE RATIONALITY/EMOTIONAL DEFENSIVENESS SCALE- I. INTERNAL STRUCTURE AND STABILITY

THE RATIONALITY/EMOTIONAL DEFENSIVENESS SCALE- I. INTERNAL STRUCTURE AND STABILITY Joouml of Psychosomaric Research, Vol. 35. No. 4/S, pp. 545-554, 1991. 0534-3999191 $3.00+.00 Printed in Great Britain 0 1991 Pergamon Press plc THE RATIONALITY/EMOTIONAL DEFENSIVENESS SCALE- I. INTERNAL

More information

NON-NARCOTIC ORALLY EFFECTIVE, CENTRALLY ACTING ANALGESIC FROM AN AYURVEDIC DRUG

NON-NARCOTIC ORALLY EFFECTIVE, CENTRALLY ACTING ANALGESIC FROM AN AYURVEDIC DRUG Journal of Ethnopharmocology, ll(l984) 309-317 Elsevier Scientific Publishers Ireland Ltd. 309 NON-NARCOTIC ORALLY EFFECTIVE, CENTRALLY ACTING ANALGESIC FROM AN AYURVEDIC DRUG CX ATAL, M.A. SIDDIQUI, USHA

More information

The conundrum of hodgkin lymphoma nodes: To be or not to be included in the involved node radiation fields. The EORTC-GELA lymphoma group guidelines

The conundrum of hodgkin lymphoma nodes: To be or not to be included in the involved node radiation fields. The EORTC-GELA lymphoma group guidelines Radiotherapy and Oncology 88 (2008) 202 210 www.thegreenjournal.com Hodgkin guidelines The conundrum of hodgkin lymphoma nodes: To be or not to be included in the involved node radiation fields. The EORTC-GELA

More information

Divergent Thinking and Evaluation Skills: Do They Always Go Together?

Divergent Thinking and Evaluation Skills: Do They Always Go Together? Journal of Creative Behavior MAGDALENA GROHMAN ZOFIA WODNIECKA MARCIN KLUSAK Divergent Thinking and Evaluation Skills: Do They Always Go Together? ABSTRACT INTRODUCTION The aim of the present study was

More information

Mastering the Initial Dissection and Cannulation: Making Ablation Easy and Safe

Mastering the Initial Dissection and Cannulation: Making Ablation Easy and Safe Chapter 5 Mastering the Initial Dissection and Cannulation: Making Ablation Easy and Safe 1 INTRODUCTION A good initial dissection with wide mobilization of the left atrium (LA) by dividing its attachments

More information

Comparison of Carotid Artery Stenting and Carotid Endarterectomy in Patients with Symptomatic Carotid Artery Stenosis: A Single Center Study

Comparison of Carotid Artery Stenting and Carotid Endarterectomy in Patients with Symptomatic Carotid Artery Stenosis: A Single Center Study Adv Ther (2013) 30:845 853 DOI 10.1007/s25-013-0058-8 ORIGINAL RESEARCH Comparison of Carotid Artery Stenting and Carotid Endarterectomy in Patients with Symptomatic Carotid Artery Stenosis: A Single Center

More information

Pharmacokinetics of a Novel Orodispersible Tablet of Sildenafil in Healthy Subjects

Pharmacokinetics of a Novel Orodispersible Tablet of Sildenafil in Healthy Subjects Clinical Therapeutics/Volume 36, Number 2, 2014 Pharmacokinetics of a Novel Orodispersible Tablet of Sildenafil in Healthy Subjects Bharat Damle, PhD 1 ; Gregory Duczynski, MS 2 ; Barrett W. Jeffers, PhD

More information

ABSTRACT. questions in the version of NorAQ administered to men (m-noraq) against the interview model.

ABSTRACT. questions in the version of NorAQ administered to men (m-noraq) against the interview model. GENDER MEDICINE/VOL. 8,NO. 2, 2011 NorVold Abuse Questionnaire for Men (m-noraq): Validation of New Measures of Emotional, Physical, and Sexual Abuse and Abuse in Health Care in Male Patients Katarina

More information

Effects of regular exercise on asthma control in young adults

Effects of regular exercise on asthma control in young adults Journal of Asthma ISSN: 0277-0903 (Print) 1532-4303 (Online) Journal homepage: http://www.tandfonline.com/loi/ijas20 Effects of regular exercise on asthma control in young adults Dr Sirpa A.M. Heikkinen,

More information

ORIGINAL ARTICLE ABSTRACT SUMMARY AT A GLANCE INTRODUCTION

ORIGINAL ARTICLE ABSTRACT SUMMARY AT A GLANCE INTRODUCTION bs_bs_banner ORIGINAL ARTICLE Budesonide/formoterol maintenance and reliever therapy via Turbuhaler versus fixed-dose budesonide/formoterol plus terbutaline in patients with asthma: Phase III study results

More information

The role of air plethysmography in the diagnosis of chronic venous insufficiency

The role of air plethysmography in the diagnosis of chronic venous insufficiency The role of air plethysmography in the diagnosis of chronic venous insufficiency Enrique Criado, MD, Mark A. Farber, MD, William A. Marston, MD, Patty F. Daniel, RN, RVT, Cynthia B. Burnham, RN, RVT, and

More information

Effects of Angle of Approach on Cursor Movement with a Mouse: Consideration of Fitts' Law

Effects of Angle of Approach on Cursor Movement with a Mouse: Consideration of Fitts' Law Pergamon Computers in Human Behavior, Vol. 12, No. 3, pp. 481-495, 1996 Copyright 1996 Elsevier Science Ltd Printed in Great Britain. All rights reserved 0747-5632/96 $15.00 + 0.00 S0747-5632(96) 00020-9

More information

RAVEN'S COLORED PROGRESSIVE MATRICES AND INTELLECTUAL IMPAIRMENT IN PATIENTS WITH FOCAL BRAIN DAMAGE

RAVEN'S COLORED PROGRESSIVE MATRICES AND INTELLECTUAL IMPAIRMENT IN PATIENTS WITH FOCAL BRAIN DAMAGE RAVEN'S COLORED PROGRESSIVE MATRICES AND INTELLECTUAL IMPAIRMENT IN PATIENTS WITH FOCAL BRAIN DAMAGE Claudio Villardita (Neuropsychology Unit, Department of Neurology, University of Catania) INTRODUCTION

More information

Hard-tissue alterations following immediate implant placement in extraction sites

Hard-tissue alterations following immediate implant placement in extraction sites J Clin Periodontol 2004; 31: 820 828 doi: 10.1111/j.1600-051X.2004.00565.x Copyright r Blackwell Munksgaard 2004 Printed in Denmark. All rights reserved Hard-tissue alterations following immediate implant

More information

Author s Accepted Manuscript

Author s Accepted Manuscript Author s Accepted Manuscript Rheumatologic symptoms in oncologic patients on PD-1 inhibitors Wilson F. Kuswanto, Lindsey A. MacFarlane, Lydia Gedmintas, Alexandra Mulloy, Toni K. Choueiri, Bonnie Bermas

More information

SYSTEMATIC REVIEW PROTOCOL

SYSTEMATIC REVIEW PROTOCOL Effectiveness of Silexan oral lavender essential oil compared to inhaled lavender essential oil aromatherapy on sleep in adults: a systematic review protocol Martha J. Greenberg 1,2 Jason T. Slyer 1,2

More information

Energy Metabolism in Oreochromis niloticus

Energy Metabolism in Oreochromis niloticus Aquuculture, 79 (1989) 283-291 Eisevier Science Pubhshers B.V., Amsterdam - Printed in The Netherlands 283 Energy Metabolism in Oreochromis niloticus K.-H. MEYER-BURGDORFF, M.F. OSMAN and K.D. GUNTHER

More information

Cost-Effectiveness of Adding Rh-Endostatin to First-Line Chemotherapy in Patients With Advanced Non-Small-Cell Lung Cancer in China

Cost-Effectiveness of Adding Rh-Endostatin to First-Line Chemotherapy in Patients With Advanced Non-Small-Cell Lung Cancer in China Clinical Therapeutics/Volume 33, Number 10, 2011 Cost-Effectiveness of Adding Rh-Endostatin to First-Line Chemotherapy in Patients With Advanced Non-Small-Cell Lung Cancer in China Bin Wu, PhD 1, Huafeng

More information

Marlowe Crowne Social Desirability Scale and Short Form C: Forensic Norms

Marlowe Crowne Social Desirability Scale and Short Form C: Forensic Norms Marlowe Crowne Social Desirability Scale and Short Form C: Forensic Norms Paul Andrews Private Practice, Tyler, Texas Robert G. Meyer University of Louisville Marlowe Crowne Social Desirability Scale (MC)

More information

Title: Clinical and histopathological features of immunoglobulin G4-associated autoimmune hepatitis in children

Title: Clinical and histopathological features of immunoglobulin G4-associated autoimmune hepatitis in children Title: Clinical and histopathological features of immunoglobulin G4-associated autoimmune hepatitis in children Short title: Immunoglobulin G4-associated autoimmune hepatitis in children Yusuf Aydemir¹,

More information

HYDRONEPHROSIS DUE TO THE INFERIOR POLAR ARTERY :

HYDRONEPHROSIS DUE TO THE INFERIOR POLAR ARTERY : HYDRONEPHROSIS DUE TO THE INFERIOR POLAR ARTERY : LATE RESULTS AFTER NEPHROPLICATION. Appendix of Recent Cases By A. WILFRID ADAMS, F.R.C.S. Bristol Royal Infirmary FOR hydronephrosis due to an aberrant,

More information

Ovarian cancer is the most lethal gynecologic malignancy

Ovarian cancer is the most lethal gynecologic malignancy Original Research Laparoscopy Compared With Laparotomy for Debulking Ovarian Cancer After Neoadjuvant Chemotherapy Alexander Melamed, MD, MPH, Roni Nitecki, MD, David M. Boruta II, MD, Marcela G. del Carmen,

More information

Validation of ATS clinical practice guideline cut-points for FeNO in asthma

Validation of ATS clinical practice guideline cut-points for FeNO in asthma Accepted Manuscript Validation of ATS clinical practice guideline cut-points for FeNO in asthma Maria Jeppegaard, Sandra Veidal, Asger Sverrild, Vibeke Backer, Celeste Porsbjerg PII: S0954-6111(18)30296-8

More information

164 J.A.H. an Laarho en et al. / International Journal of Pharmaceutics 232 (2002) An example of a sustained release system is a contraceptive

164 J.A.H. an Laarho en et al. / International Journal of Pharmaceutics 232 (2002) An example of a sustained release system is a contraceptive International Journal of Pharmaceutics 232 (2002) 163 173 www.elsevier.com/locate/ijpharm In vitro release properties of etonogestrel and ethinyl estradiol from a contraceptive vaginal ring J.A.H. van

More information

Parallel Stent Graft Techniques to Facilitate Endovascular Repair in the Aortic Arch

Parallel Stent Graft Techniques to Facilitate Endovascular Repair in the Aortic Arch Parallel Stent Graft Techniques to Facilitate Endovascular Repair in the Aortic Arch 35 Frank J. Criado Introduction Whether using a traditional open-chest approach or endovascular techniques, the arch

More information

Prevalence of different HIV-1 subtypes in sexual transmission in China: a systematic review and meta-analysis

Prevalence of different HIV-1 subtypes in sexual transmission in China: a systematic review and meta-analysis Epidemiol. Infect. (2016), 144, 2144 2153. Cambridge University Press 2016 doi:10.1017/s0950268816000212 Prevalence of different HIV-1 subtypes in sexual transmission in China: a systematic review and

More information

Nebulized Magnesium for Moderate and Severe Pediatric Asthma: A Randomized Trial

Nebulized Magnesium for Moderate and Severe Pediatric Asthma: A Randomized Trial 50:1191 1199 (2015) Nebulized Magnesium for Moderate and Severe Pediatric Asthma: A Randomized Trial Khalid Alansari, MD, FRCPC, FAAP(PEM), 1,2,3 * Wessam Ahmed, 2 Bruce L. Davidson, MD, MPH, 4 Mohamed

More information

A Diabetes Mobile App With In-App Coaching From a Certified Diabetes Educator Reduces A1C for Individuals With Type 2 Diabetes

A Diabetes Mobile App With In-App Coaching From a Certified Diabetes Educator Reduces A1C for Individuals With Type 2 Diabetes 765650TDEXXX10.1177/0145721718765650Impact of a Diabetes App and Coaching Program on A1CKumar et al research-article2018 Impact of a Diabetes App and Coaching Program on A1C 1 A Diabetes Mobile App With

More information

Contrasting timing of virological relapse after discontinuation of. tenofovir or entecavir in hepatitis B e antigen-negative patients.

Contrasting timing of virological relapse after discontinuation of. tenofovir or entecavir in hepatitis B e antigen-negative patients. Contrasting timing of virological relapse after discontinuation of tenofovir or entecavir in hepatitis B e antigen-negative patients. Running title: Difference after stopping TDF or ETV Christoph Höner

More information

Computerized Quantitative Coronary Angiography Applied to Percutaneous Transluminal Coronary Angioplasty: Advantages and Limitations

Computerized Quantitative Coronary Angiography Applied to Percutaneous Transluminal Coronary Angioplasty: Advantages and Limitations Computerized Quantitative Coronary Angiography Applied to Percutaneous Transluminal Coronary Angioplasty: Advantages and Limitations P.W. Serruys, F. Booman, G.J. Troost, J.H.C. Reiber, J.J. Gerbrands*,

More information

Natural Course of Peripartum Cardiomyopathy

Natural Course of Peripartum Cardiomyopathy Natural Course of Peripartum Cardiomyopathy By JOHN G. DEMAKIS, M.D., SHAHBUDIN H. RAHIMTOOLA, M.B., M.R.C.P.E., GEORGE C. SUTrON, M.D., W. ROBERT MEADOWS, M.D., PAUL B. SZANTO, M.D., JoHN R. TOBIN, M.D.,

More information

Pulmonary Vein Stenosis After Catheter Ablation of Atrial Fibrillation

Pulmonary Vein Stenosis After Catheter Ablation of Atrial Fibrillation Pulmonary Vein Stenosis After Catheter Ablation of Atrial Fibrillation E.B. SAAD Introduction Catheter ablation around the pulmonary veins (PVs) has become the treatment of choice for symptomatic patients

More information

Introduction. urinary erythropoietin, and the two are indistinguishable

Introduction. urinary erythropoietin, and the two are indistinguishable BIOPHARMACEUTICS & DRUG DISPOSITION Biopharm. Drug Dispos. 21: 211 219 (2000) DOI: 10.1002/bdd.231 Comparative Pharmacokinetics, Safety, and Tolerability After Subcutaneous Administration of Recombinant

More information

A Motivational Intervention to Reduce Cigarette

A Motivational Intervention to Reduce Cigarette A Motivational Intervention to Reduce Cigarette Smoking Among College Students: Overview and Exploratory Investigation Keith C. Herman and Beth Fahnlander College counselors can play an important role

More information

Low- vs. high-pressure suction drainage after total knee arthroplasty: a double-blind randomized controlled trial

Low- vs. high-pressure suction drainage after total knee arthroplasty: a double-blind randomized controlled trial JAN JOURNAL OF ADVANCED NURSING ORIGINAL RESEARCH Low- vs. high-pressure suction drainage after total knee arthroplasty: a double-blind randomized controlled trial Rafael Calvo, M a José Martínez-Zapata,

More information

The Use of Transdermal Buprenorphine to Relieve Radiotherapy-Related Pain in Head and Neck Cancer Patients

The Use of Transdermal Buprenorphine to Relieve Radiotherapy-Related Pain in Head and Neck Cancer Patients Cancer Investigation, 31:412 420, 2013 ISSN: 0735-7907 print / 1532-4192 online Copyright C 2013 Informa Healthcare USA, Inc. DOI: 10.3109/07357907.2013.800094 IMAGING, DIAGNOSIS, PROGNOSIS The Use of

More information

Incidence and predictors of synchronous liver metastases in patients with gastrointestinal stromal tumors (GISTs)

Incidence and predictors of synchronous liver metastases in patients with gastrointestinal stromal tumors (GISTs) Accepted Manuscript Incidence and predictors of synchronous liver metastases in patients with gastrointestinal stromal tumors (GISTs) Apostolos Gaitanidis, Michail Alevizakos, Alexandra Tsaroucha, Constantinos

More information

A. Alonso-Burgos a, *, E. García-Tutor b, G. Bastarrika a, D. Cano a, A. Martínez-Cuesta a, L.J. Pina a

A. Alonso-Burgos a, *, E. García-Tutor b, G. Bastarrika a, D. Cano a, A. Martínez-Cuesta a, L.J. Pina a Journal of Plastic, Reconstructive & Aesthetic Surgery (2006) 59, 585 593 Preoperative planning of deep inferior epigastric artery perforator flap reconstruction with multislice-ct angiography: imaging

More information

Journal of Chromatography B, 857 (2007)

Journal of Chromatography B, 857 (2007) Journal of Chromatography B, 857 (2007) 287 295 Determination of serum uric acid using high-performance liquid chromatography (HPLC)/isotope dilution mass spectrometry (ID-MS) as a candidate reference

More information

A LABORATORY TASK FOR INDUCTION OF MOOD STATES*

A LABORATORY TASK FOR INDUCTION OF MOOD STATES* khav. Res. & Therapy. 1968. Vol. 6. pp. 473 to 462. Pergamon Press. Printed in Englmd A LABORATORY TASK FOR INDUCTION OF MOOD STATES* EMMETT VELTEN, JR.? University of Southern California (Received 15

More information

Clinical investigation of chronic subdural hematoma with impending brain herniation on arrival

Clinical investigation of chronic subdural hematoma with impending brain herniation on arrival DOI 10.1007/s10143-017-0861-9 ORIGINAL ARTICLE Clinical investigation of chronic subdural hematoma with impending brain herniation on arrival Hiroaki Matsumoto 1 & Hiroaki Hanayama 1 & Takashi Okada 1

More information

Splenomegaly and Hemolytic Anemia Induced in Rats by Methylcellulose - An electron microscopic study '

Splenomegaly and Hemolytic Anemia Induced in Rats by Methylcellulose - An electron microscopic study ' Splenomegaly and Hemolytic Anemia Induced in Rats by Methylcellulose - An electron microscopic study ' EMMA WENNBERG AND LEON WEISS Department of Anatomy, The johns Hopkins University School of Medicine,

More information

Pulley lesions in rotator cuff tears: prevalence, etiology, and concomitant pathologies

Pulley lesions in rotator cuff tears: prevalence, etiology, and concomitant pathologies Arch Orthop Trauma Surg (2017) 137:1097 1105 DOI 10.1007/s00402-017-2721-z ARTHROSCOPY AND SPORTS MEDICINE Pulley lesions in rotator cuff tears: prevalence, etiology, and concomitant pathologies Nael Hawi

More information

Yang S-S, Gao Y, Wang D-Y, Xia B-R, Liu Y-D, Qin Y, Ning X-M, Li G-Y, Hao L-X, Xiao M & Zhang Y-Y (2016) Histopathology. DOI: /his.

Yang S-S, Gao Y, Wang D-Y, Xia B-R, Liu Y-D, Qin Y, Ning X-M, Li G-Y, Hao L-X, Xiao M & Zhang Y-Y (2016) Histopathology. DOI: /his. Histopathology 2016 DOI: 10.1111/his.12933 Overexpression of eukaryotic initiation factor 5A2 (EIF5A2) is associated with cancer progression and poor prognosis in patients with early-stage cervical cancer

More information

Effect of health Baduanjin Qigong for mild to moderate Parkinson s disease

Effect of health Baduanjin Qigong for mild to moderate Parkinson s disease bs_bs_banner Geriatr Gerontol Int 2016; 16: 911 919 ORIGINAL ARTICLE: EPIDEMIOLOGY, CLINICAL PRACTICE AND HEALTH Effect of health Baduanjin Qigong for mild to moderate Parkinson s disease Chun-Mei Xiao

More information

Glucose-lowering activity of the dipeptidyl peptidase-4 inhibitor saxagliptin in drug-naive patients with type 2 diabetes*

Glucose-lowering activity of the dipeptidyl peptidase-4 inhibitor saxagliptin in drug-naive patients with type 2 diabetes* ORIGINAL ARTICLE doi: 10.1111/j.1463-1326.2008.00876.x Glucose-lowering activity of the dipeptidyl peptidase-4 inhibitor saxagliptin in drug-naive patients with type 2 diabetes* J. Rosenstock, 1 S. Sankoh

More information

Colchicine for prevention and treatment of cardiac diseases: A meta-analysis

Colchicine for prevention and treatment of cardiac diseases: A meta-analysis DOI: 10.1111/1755-5922.12226 ORIGINAL RESEARCH ARTICLE Colchicine for prevention and treatment of cardiac diseases: A meta-analysis Nikolaos Papageorgiou 1,2, Alexandros Briasoulis 3, George Lazaros 2

More information

Antiproliferative, antimigratory, and anticlonogenic effects of Hedyotis diffusa, Panax ginseng, and their combination on colorectal cancer cell lines

Antiproliferative, antimigratory, and anticlonogenic effects of Hedyotis diffusa, Panax ginseng, and their combination on colorectal cancer cell lines Journal of Herbs, Spices & Medicinal Plants ISSN: 1049-6475 (Print) 1540-3580 (Online) Journal homepage: http://www.tandfonline.com/loi/whsm20 Antiproliferative, antimigratory, and anticlonogenic effects

More information

Efficacy, safety and impact on β

Efficacy, safety and impact on β J Endocrinol Invest (2016) 39:1061 1074 DOI 10.1007/s40618-016-0465-1 ORIGINAL ARTICLE Efficacy, safety and impact on β cell function of dipeptidyl peptidase 4 inhibitors plus metformin combination therapy

More information

Development and psychometric evaluation of the Thirst Distress Scale for patients with heart failure

Development and psychometric evaluation of the Thirst Distress Scale for patients with heart failure 728624CNU0010.1177/1474515117728624European Journal of Cardiovascular Nursing 0(0)Waldréus et al. research-article2017 Original Article Development and psychometric evaluation of the Thirst Distress Scale

More information

Memory-based attentional capture by colour and shape contents in visual working memory

Memory-based attentional capture by colour and shape contents in visual working memory Visual Cognition ISSN: 1350-6285 (Print) 1464-0716 (Online) Journal homepage: http://www.tandfonline.com/loi/pvis20 Memory-based attentional capture by colour and shape contents in visual working memory

More information

Small pulmonary nodules in baseline and incidence screening rounds of low-dose CT lung cancer screening

Small pulmonary nodules in baseline and incidence screening rounds of low-dose CT lung cancer screening Review Article Small pulmonary nodules in baseline and incidence screening rounds of low-dose CT lung cancer screening Joan E. Walter, Marjolein A. Heuvelmans, Matthijs Oudkerk University Medical Center

More information

Reliability and Factorial Structure of the Chinese Version of the State-Trait Anxiety Inventory

Reliability and Factorial Structure of the Chinese Version of the State-Trait Anxiety Inventory Journal of Psychopathology and Behavioral Assessment, Vol. 10, No. 4, 1988 Reliability and Factorial Structure of the Chinese Version of the State-Trait Anxiety Inventory Daniel T. L. Shek ~ Accepted:

More information

Serum mir-182 and mir-331-3p as diagnostic and prognostic markers in patients with hepatocellular carcinoma

Serum mir-182 and mir-331-3p as diagnostic and prognostic markers in patients with hepatocellular carcinoma Tumor Biol. (2015) 36:7439 7447 DOI 10.1007/s13277-015-3430-2 RESEARCH ARTICLE Serum mir-182 and mir-331-3p as diagnostic and prognostic markers in patients with hepatocellular carcinoma Lin Chen 1 & Feihu

More information

Lisfranc Arthrodesis for Chronic Pain: A Cannulated Screw Technique

Lisfranc Arthrodesis for Chronic Pain: A Cannulated Screw Technique Lisfranc Arthrodesis for Chronic Pain: A Cannulated Screw Technique Nine patients with injury to the tarsometatarsal joint underwent fusion with cannulated screw fixation after conservative treatment had

More information

Functional Outcome of Unstable Distal Radius Fractures: ORIF With a Volar Fixed-Angle Tine Plate Versus External Fixation

Functional Outcome of Unstable Distal Radius Fractures: ORIF With a Volar Fixed-Angle Tine Plate Versus External Fixation Functional Outcome of Unstable Distal Radius Fractures: ORIF With a Volar Fixed-Angle Tine Plate Versus External Fixation Thomas W. Wright, MD, MaryBeth Horodyski, EdD, Gainesville, FL, Dean W. Smith,

More information

Congenital absence of teeth is a common dental

Congenital absence of teeth is a common dental CASE REPORT Management of congenitally missing second premolars with orthodontics and single-tooth implants Roy Sabri, DDS, MS Beirut, Lebanon This article describes the treatment of an adolescent girl

More information

LONG-TERM RESULTS OF A PHASE III TRIAL COMPARING ONCE-DAILY RADIOTHERAPY WITH TWICE-DAILY RADIOTHERAPY IN LIMITED- STAGE SMALL-CELL LUNG CANCER

LONG-TERM RESULTS OF A PHASE III TRIAL COMPARING ONCE-DAILY RADIOTHERAPY WITH TWICE-DAILY RADIOTHERAPY IN LIMITED- STAGE SMALL-CELL LUNG CANCER doi:10.1016/j.ijrobp.2004.01.055 Int. J. Radiation Oncology Biol. Phys., Vol. 59, No. 4, pp. 943 951, 2004 Copyright 2004 Elsevier Inc. Printed in the USA. All rights reserved 0360-3016/04/$ see front

More information

Address: Department of General Surgery, Royal Bolton Hospital, Bolton, UK. ; tel:

Address: Department of General Surgery, Royal Bolton Hospital, Bolton, UK.   ; tel: Article type : Systematic Review Accepted Article 875-2017.R1 Systematic Review Effect of mesalazine on recurrence of diverticulitis in patients with symptomatic uncomplicated diverticular disease: a meta-analysis

More information

EGC Diagnosis of Paroxysmal Supraventricular Tachycardias in Patients without Preexcitation

EGC Diagnosis of Paroxysmal Supraventricular Tachycardias in Patients without Preexcitation REVIEW ARTICLE EGC Diagnosis of Paroxysmal Supraventricular Tachycardias in Patients without Preexcitation Esteban González-Torrecilla, M.D., Ph.D., Angel Arenal, M.D., Felipe Atienza, M.D., Ph.D., Tomás

More information

Protective effect of HTK solution on postoperative pulmonary function in infants with CHD and PAH

Protective effect of HTK solution on postoperative pulmonary function in infants with CHD and PAH Bioscience Reports: this is an Accepted Manuscript, not the final Version of Record. You are encouraged to use the Version of Record that, when published, will replace this version. The most up-to-date

More information

A disease- specific quality of life instrument for non- alcoholic fatty liver disease and non- alcoholic steatohepatitis: CLDQ- NAFLD

A disease- specific quality of life instrument for non- alcoholic fatty liver disease and non- alcoholic steatohepatitis: CLDQ- NAFLD Received: 10 November 2016 Accepted: 8 February 2017 DOI: 10.1111/liv.13391 METABOLIC LIVER DISEASE A disease- specific quality of life instrument for non- alcoholic fatty liver disease and non- alcoholic

More information

Epithelial Barrier Defects in HT-29/B6 Colonic Cell Monolayers Induced by Tumor Necrosis Factor α

Epithelial Barrier Defects in HT-29/B6 Colonic Cell Monolayers Induced by Tumor Necrosis Factor α Epithelial Barrier Defects in HT-29/B6 Colonic Cell Monolayers Induced by Tumor Necrosis Factor α ALFRED H. GITTER, a,b KERSTIN BENDFELDT, a HEINZ SCHMITZ, c JÖRG-DIETER SCHULZKE, c CARL J. BENTZEL, d

More information

Effects of Mattress Material on Body Pressure Profiles in Different Sleeping Postures

Effects of Mattress Material on Body Pressure Profiles in Different Sleeping Postures Effects of Mattress Material on Body Pressure Profiles in Different Sleeping Postures Fan-Zhe Low, BEng, Matthew Chin-Heng Chua, PhD, Pan-Yin Lim, BEng, and Chen-Hua Yeow, PhD ABSTRACT Objectives: This

More information

Gomputed tomography of the normal temporomaandibular joint

Gomputed tomography of the normal temporomaandibular joint Gomputed tomography of the normal temporomaandibular joint EDWIN h. GHRISTiANSENi, TERENCE T: CHAN^, JOSEPH R. THOMPSON^ ANTON N. HASSO', DAVID B. HINSHAW JR' AND SIGVARD KOPP* ^Department of Endodontics^

More information

Training for Lung Ultrasound Score Measurement in Critically Ill Patients

Training for Lung Ultrasound Score Measurement in Critically Ill Patients Page 1 of 1 Training for Lung Ultrasound Score Measurement in Critically Ill Patients Jean-Jacques Rouby, M.D., Ph.D. Charlotte Arbelot, M.D., Multidisciplinary Intensive Care Unit, Department of Anesthesiology

More information

Electrical Acupoint Stimulation Changes Body Composition and the Meridian Systems in Postmenopausal Women with Obesity

Electrical Acupoint Stimulation Changes Body Composition and the Meridian Systems in Postmenopausal Women with Obesity The American Journal of Chinese Medicine, Vol. 38, No. 4, 683 694 2010 World Scientific Publishing Company Institute for Advanced Research in Asian Science and Medicine DOI: 10.1142/S0192415X10008159 Electrical

More information

Combining ECMO with IABP for the Treatment of Critically Ill Adult Heart Failure Patients

Combining ECMO with IABP for the Treatment of Critically Ill Adult Heart Failure Patients Heart, Lung and Circulation (2014) 23, 363 368 1443-9506/04/$36.00 http://dx.doi.org/10.1016/j.hlc.2013.10.081 ORIGINAL ARTICLE Combining ECMO with IABP for the Treatment of Critically Ill Adult Heart

More information

Hepatitis B virus (HBV) infection is a global health

Hepatitis B virus (HBV) infection is a global health GASTROENTEROLOGY 2012;142:1140 1149 High Levels of Hepatitis B Surface Antigen Increase Risk of Hepatocellular Carcinoma in Patients With Low HBV Load TAI CHUNG TSENG,*,, ** CHUN JEN LIU,, HUNG CHIH YANG,,#

More information

Treatment of Class III Malocclusions Using Miniplate and Mini-Implant Anchorage

Treatment of Class III Malocclusions Using Miniplate and Mini-Implant Anchorage Treatment of Class III Malocclusions Using Miniplate and Mini-Implant Anchorage Seung-Hak Baek, Il-Hyung Yang, Keun-Woo Kim, and Hyo-Won Ahn Orthodontic miniplates and mini-implants have become essential

More information

Lung cancer is one of the major tumors that causes human

Lung cancer is one of the major tumors that causes human ORIGINAL RESEARCH Analysis of Contrast-Enhanced Ultrasound Perfusion Patterns and Time-Intensity Curves for Metastatic Lymph Nodes From Lung Cancer Preliminary Results Shanshan Yin, MD, Qiuli Cui, MSc,

More information

Tumor Spread Through Air Spaces Identifies a Distinct Subgroup With Poor Prognosis in Surgically Resected Lung Pleomorphic Carcinoma

Tumor Spread Through Air Spaces Identifies a Distinct Subgroup With Poor Prognosis in Surgically Resected Lung Pleomorphic Carcinoma 1 2 3 4 5 6 7 8 9 1 11 12 13 14 15 16 17 18 19 21 22 23 24 25 26 27 28 29 3 31 32 33 34 35 36 37 38 39 41 42 43 44 45 46 47 48 49 5 51 52 53 54 55 Q15 Q1 Q6 Q2 [ Original Research ] Tumor Spread Through

More information

Effects of cigarette smoking on psychopathology scores in patients with schizophrenia: An experimental study

Effects of cigarette smoking on psychopathology scores in patients with schizophrenia: An experimental study Substance Abuse ISSN: 0889-7077 (Print) 1547-0164 (Online) Journal homepage: http://www.tandfonline.com/loi/wsub20 Effects of cigarette smoking on psychopathology scores in patients with schizophrenia:

More information

Changes in nocturnal sleep and daytime nap durations predict all-cause mortality

Changes in nocturnal sleep and daytime nap durations predict all-cause mortality Changes in nocturnal sleep and daytime nap durations predict all-cause mortality among older adults: the Panel on Health and Ageing of Singaporean Elderly Grand H.-L. Cheng, PhD 1, *; Rahul Malhotra, MD

More information

Use of Digoxin for Heart Failure and Atrial Fibrillation in Elderly Patients

Use of Digoxin for Heart Failure and Atrial Fibrillation in Elderly Patients J.W.M. Cheng and I. Rybak The American Journal of Geriatric Pharmacotherapy Use of Digoxin for Heart Failure and Atrial Fibrillation in Elderly Patients Judy W.M. Cheng, BS, PharmD, MPH 1,2 ; and Iwona

More information

Hong-qi Zhang Min-zhong Lin Jin-song Li Ming-xing Tang Chao-feng Guo Jian-huang Wu Jin-yang Liu

Hong-qi Zhang Min-zhong Lin Jin-song Li Ming-xing Tang Chao-feng Guo Jian-huang Wu Jin-yang Liu Arch Orthop Trauma Surg (2013) 133:333 341 DOI 10.1007/s00402-012-1669-2 ORTHOPAEDIC SURGERY One-stage posterior debridement, transforaminal lumbar interbody fusion and instrumentation in treatment of

More information

In vivo diagnosis of early-stage gastric cancer found after. Helicobacter pylori eradication using probe-based confocal laser endomicroscopy

In vivo diagnosis of early-stage gastric cancer found after. Helicobacter pylori eradication using probe-based confocal laser endomicroscopy DR. NAOKI OHMIYA (Orcid ID : 0000-0002-7651-402X) Accepted Article Article type : Original article In vivo diagnosis of early-stage gastric cancer found after Helicobacter pylori eradication using probe-based

More information

Angewandte. A Journal of the Gesellschaft Deutscher Chemiker. Accepted Article

Angewandte. A Journal of the Gesellschaft Deutscher Chemiker. Accepted Article Angewandte A Journal of the Gesellschaft Deutscher Chemiker International Edition Chemie www.angewandte.org Accepted Article Title: Oxygen Vacancy Enhances CO Production over ZnO Nanosheets towards CO2

More information

Absolute monocyte count predicts overall survival in mantle cell lymphomas: correlation with tumourassociated

Absolute monocyte count predicts overall survival in mantle cell lymphomas: correlation with tumourassociated Hematological Oncology Hematol Oncol 2014; 32: 178 186 Published online 29 October 2013 in Wiley Online Library (wileyonlinelibrary.com).2106 Original Research Article Absolute monocyte count predicts

More information

Different estrogen receptor β expression in distinct histologic subtypes of lung adenocarcinoma B

Different estrogen receptor β expression in distinct histologic subtypes of lung adenocarcinoma B Human Pathology (2008) 39, 1465 1473 www.elsevier.com/locate/humpath Original contribution Different estrogen receptor β expression in distinct histologic subtypes of lung adenocarcinoma B Greta Alì MD

More information