2014 PhD Psychology University of Calgary, AB, Canada Dissertation title: Non Photic Phase Shifting: Acetylcholine and Arousal

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1 CALGARY, AB PHONE: (403) An innovative published scientist with over ten years of research experience in the fields of biology, psychology and health science. A recognized expert in circadian rhythms with a proven track record of receiving academic awards, government grants and invited collaboration with other labs in the research community. An experienced presenter at scientific conferences and guest lecturer in universities with a passion for teaching and learning. A seasoned mentor in leading and motivating students to acquire analytical and critical thinking skills. EDUCATION 2014 PhD Psychology Dissertation title: Non Photic Phase Shifting: Acetylcholine and Arousal 2009 MSc Psychology Thesis title: Raphe Modulation of Circadian Phase 2006 BA (HONS) Major: Psychology, Minor: Criminology PEER REVIEWED PUBLICATIONS Salberg S, Christensen J, Yamakawa GR, Lengkeek C, Malik H, Tabor J, Hazari A, Mychaisuk R (2018) A bump on the head or late to bed: The behavioural and pathophysiological effects of sleep deprivation following repetitive mild traumatic brain injury in adolescent rats. Journal of Neurotrauma. (In Press) Yamakawa GR, Lengkeek C, Salberg S, Spanswick SC, Mychasiuk R (2017) Behavioral and pathophysiological outcomes associated with caffeine consumption and repetitive mild traumatic brain injury (RmTBI) in adolescent rats. PLoS One 12: e Salberg S, Yamakawa GR, Christensen J, Kolb B, Mychasiuk R (2017) Assessment of a nutritional supplement containing resveratrol, prebiotic fiber, and omega-3 fatty acids for the prevention and treatment of mild traumatic brain injury in rats. Neuroscience 365: Yamakawa GR, Salberg S, Barlow KM, Brooks BL, Esser M, Yeates KO, Mychasiuk R (2017) Manipulating cognitive reserve: Pre-injury environmental conditions influence the severity of concussion symptomology, gene expression, and response to melatonin treatment in rats. Experimental Neurology 295: Yamakawa GR, Basu P, Cortese F, MacDonnell J, Whalley D, Smith VM, Antle MC (2016) The cholinergic forebrain arousal system acts directly on the circadian pacemaker. Proceedings for the National Academy of Sciences USA 113: Sterniczuk R, Yamakawa GR, Pomeroy T, Antle MC (2014) Phase delays to light and gastrin releasing peptide require the protein kinase A pathway. Neuroscience Letters 559:24-29.

2 PAGE 2 Scullion K, Boychuk JA, Yamakawa GR, Rodych JTG, Nakanishi ST, Seto A, Smith VM, McCarthy R, Whelan PJ, Antle MC, Pittman QJ Teskey GC (2013) A role for serotonin 1A receptors in the expression of movement representations. Journal of Neuroscience 33: Yamakawa GR, Antle MC (2010) Phenotype and function of raphe projections to the suprachiasmatic nucleus. European Journal of Neuroscience 31: Antle MC, Smith VM, Sterniczuk R, Yamakawa GR, Rakai BD (2009) Physiological responses of the circadian clock to acute light exposure at night. Reviews in Endocrine and Metabolic Disorders 10: Landry GJ, Yamakawa GR, Webb IC, Mear RJ, Mistlberger RE (2007) The dorsomedial hypothalamic nucleus is not necessary for the expression of circadian food-anticipatory activity in rats. Journal of Biological Rhythms 22: Landry GJ, Yamakawa GR, Mistlberger RE (2007) Robust food anticipatory circadian rhythms in rats with complete ablation of the thalamic paraventricular nucleus. Brain Research 1141: PRESENTATIONS AND ABSTRACTS Yamakawa GR, Weerawardhena H, Antle MC, Mychasiuk R (2018) Neonatal MSG treatment alters outcome to repetitive mild traumatic brain injury in adolescent rats: Behavioral, Circadian and Epigenetic Changes. Poster presented at the 16 th biennial meeting of the Society for Research on Biological Rhythms in Amelia Island, FLA, USA. Weerawardhena H, Yamakawa GR, Mychasiuk R (2018) Monosodium glutamate alters the outcome to repetitive mild traumatic brain injury. Research presented in an oral PowerPoint presentation at the Canadian Spring Conference on Behaviour and Brain in Fernie, BC. Yamakawa GR, Weerawardhena H, Mychasiuk R (2017) Circadian rhythms in adolescent rats sustaining repetitive mild traumatic brain injury. Poster presented at the 47 th annual Society for Neuroscience meeting in Washington, D.C, USA Yamakawa GR, Lengkeek C, Salberg S, Spanswick SC, Mychasiuk R (2017) Caffeine consumption alters the outcome to repetitive mild traumatic brain injury in rats. Research presented in an oral PowerPoint presentation at the Traumatic Brain Injury NeuroTeam Retreat in Calgary, AB. Lengkeek C, Yamakawa GR, Salberg S, Spanswick S, Mychasiuk R (2017) Effects of caffeine pre-exposure on recovery from traumatic brain injury during development. Poster presented at the Hotchkiss Brain Institute Annual Summer Student Symposium in Calgary, AB. Yamakawa GR, Wang M, Salberg S, Mychasiuk R (2017) Caffeine consumption in adolescent rats alters outcome to mild traumatic brain injury. Poster presented at the Hotchkiss Brain Institute 13 th annual research day in Calgary, AB.

3 PAGE 3 Yamakawa GR, Wang M, Salberg S, Mychasiuk R (2017) Caffeine and traumatic brain injury in adolescent rats. Poster presented at the Alberta Children s Hospital Research Institute Symposium in Calgary, AB. Yamakawa GR, Mychasiuk R (2017) Circadian rhythms in repetitive mild traumatic brain injury. Research presented in an oral PowerPoint presentation at the Canadian Spring Conference on Behaviour and Brain in Fernie, BC. Yamakawa GR, Yu K, Yeates K, Mychasiuk R (2016) Manipulating cognitive reserve: Pre-injury environmental conditions influence the severity of concussion symptomology and pathophysiology. Poster presented at the Gairdner Symposium on Concussion in Calgary, AB Yamakawa GR (2015) The basal forebrain cholinergic neurons project directly to the suprachiasmatic nucleus and can act to produce midday phase advances. Research presented in an oral PowerPoint presentation at the second annual Midwestern chronobiology conference in Kent, Ohio, USA. Yamakawa GR, Antle MC (2014) Acetylcholine participates in non-photic phase shifting of the circadian clock. Poster presented at the 14 th biennial meeting of the Society for Research on Biological Rhythms in Big Sky, Montana, USA. Pomeroy T, Yamakawa GR, Antle MC (2012) Blocking PKA attenuates photic phase shifts in the early subjective night. Poster presented at the 13 th biennial meeting of the Society for Research on Biological Rhythms in Sandestin, FLA, USA. Yamakawa GR, Antle MC (2012) Acetylcholine participates in non-photic phase shifting of the circadian clock. Poster presented at the 13 th biennial meeting of the Society for Research on Biological Rhythms in Sandestin, FLA, USA. Scullion K, Yamakawa GR, Antle MC, Teskey GC (2010) Role of serotonin on the expression of rat motor maps. Poster presented at the 40 th annual Society for Neuroscience meeting in San Diego CA, USA. Yamakawa GR, Antle MC (2010) The serotonergic innervation of the SCN is necessary for median raphe nucleus stimulation induced phase shifts. Poster presented at the 12 th biennial meeting of the Society for Research on Biological Rhythms in Sandestin, FLA, USA. Yamakawa GR, Antle MC (2009) Identifying non-serotonergic midbrain raphe cells that project to the suprachiasmatic nucleus. Poster presented at the 2 nd annual meeting of the Canadian Association for Neuroscience in Vancouver, BC Canada. Yamakawa GR, Antle MC (2008) Further examination of median raphe projections to the suprachiasmatic nucleus in Syrian hamsters. Poster presented at the 11 th biennial meeting of the Society for Research on Biological Rhythms in Sandestin, FLA, USA.

4 PAGE 4 Landry GJ, Yamakawa GR, Mear RJ, Mistlberger RE (2007) Neural mechanisms of circadian foodanticipatory activity: replication study provides no evidence that the dorsomedial hypothalamus is critical. Poster presented at the 37 th annual Society for Neuroscience meeting in San Diego, CA, USA. Landry GJ, Yamakawa GR, Webb IC, Mistlberger RE (2006) Effects of tuberomammillary nucleus ablation on food anticipatory circadian rhythms in rats. Poster presented at the 10 th biennial meeting of the Society for Research on Biological Rhythms in Sandestin, FLA, USA. HONOURS / AWARDS 2013 Alberta Innovates Health Solutions (AIHS) 1 Year Renewal: Studentship $30,000 with a $2000 research allowance 2011 Alberta Innovates Health Solutions (AIHS) Studentship $30,000/yr with a $2000 research allowance 2010 Canadian Psychological Association Certificate of Academic Excellence University of Calgary Award for top Master s Thesis 2010 Dean s Research Excellence Award University of Calgary $3, Society for Research on Biological Rhythms Conference Merit Award $ Canadian Association for Neuroscience Eli Lily Young Neuroscientist Award $ Dean s Research Excellence Award University of Calgary $3, Natural Sciences and Engineering Research Council of Canada (NSERC) Post Graduate D3 Doctoral Scholarship $63,000 over 36 months 2009 Natural Sciences and Engineering Research Council (NSERC) Alexander Graham Bell Canadian Graduate Scholarship $17, Natural Sciences and Engineering Research Council (NSERC) Post Graduate Masters Scholarship $17,300

5 PAGE Faculty of 1000 Biology Website Landry et al., 2007 selected for website 2006 Psychology Alumni Honours Prize Simon Fraser University Top Honours Thesis $500 RESEARCH EXPERIENCE 2016-Present Postdoctoral Research Associate Alberta Children s Hospital Research Institute, Calgary, AB, Canada (Circadian rhythms in adolescent traumatic brain injury) Lab Manager Coordinated the daily lab operations including supplies stocking, research techniques, disposal of hazardous waste and preparing data for publication Postdoctoral Research Associate Conducted pilot research involving ethanol consumption in mice Kent State University, Ohio, USA (Specific knockdown of Per2 in circadian and reward related areas alters ethanol consumption) Graduate Researcher: Doctor of Philosophy (The role of arousal related neurotransmitters in non-photic phase shifting, Chronobiology Lab) Graduate Researcher: Masters of Science (Serotonergic Modulation of Circadian Phase, Chronobiology Lab) Lab Technician (Circadian Rhythms Lab) Undergraduate Researcher: Honours Project (The tuberomammillary nucleus is not necessary for the expression of food anticipatory activity.) 2005 Research Assistant (Circadian Rhythms Lab) 2005 Research Assistant

6 PAGE 6 (Behavioural Neuroendocrinology Lab) TEACHING EXPERIENCE 2018 Mentor/Lab Supervisor Alberta Children s Hospital Research Institute, Calgary, AB (Himanthri Weerawardhena undergraduate honours student) (Project: The role of MSG on mild traumatic brain injury-associated outcomes in adolescent rats) 2017 Instructor Ambrose University, Calgary, AB, Canada Psychology 330 Brain and Behaviour 2015 Guest Lecturer Ambrose University, Calgary, AB, Canada States of consciousness 2012 Guest Lecturer University of Calgary, Calgary, AB, Canada Food anticipatory activity and the food entrainable oscillator 2012 Instructional Skills Workshop Certificate Teaching and Learning Centre, 2012 Mentor/ Lab Supervisor (Tara Pomeroy, undergraduate honours student) (Project: Blocking PKA attenuates photic phase shifts in the early subjective night.) 2011 Mentor/ Lab Supervisor (Danica Whalley, undergraduate honours student) (Project: Fos activation in arousal related areas of sleep deprived hamsters.) 2010 Lab Instructor (Course: Human Neuropsychology) 2009 Tutor/Marker (Course: Brain and Behaviour) Lab Instructor (Course: Experimental Design and Quantitative Methods in Psychology)

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