Beyond our eyes: the non-visual impact of light
|
|
- Tracey June Newton
- 5 years ago
- Views:
Transcription
1 Beyond our eyes: the non-visual impact of light Christian Cajochen, PhD Centre for Chronobiology Psychiatric Hospital of the University of Basel, Switzerland Workshop Intelligent Efficient Human Centric Lighting Muttenz/Basel 12.. December 2016
2 Thomas Edison was maybe wrong!
3 Light is the most important Zeitgeber! Buttgereit, Smolen, Coogan, Cajochen, Nat Rev Rheumatol, 2015
4 Plasma Melatonin (pmol/l) Light and human circadian rhythms Melatonin as the best circadian marker in humans Induction of a Phase Delay in the Human Circadian Melatonin Rhythm by Light ( lux for 6.5 h) Midpoint 4:45 Midpoint 8: Light Time of Day Sleep period Khalsa et al., J Physiol (London) 2003
5 Phase shift (h) Light and circadian phase Phase-Response Curve Initial Phase (time relative to DLMO=0) 6.7 hours lux polychromatic white Retina light Khalsa, et al., J Physiol (London) 2003
6 «Light impacts on our circadian rhythms more powerfully than any drug» Charles Czeisler «Casting light on sleep deficiency» Nature, 2013
7 Suppression of melatonin in a totally blind person with bright light 300 Sighted Person Plasma Melatonin (pmol/liter) Core Body Temperature ( C) Time of Day (h) Blind Person Plasma Melatonin (pmol/liter) Time of Day (h) Core Body Temperature ( C) Czeisler et al., New Engl Med 1995
8 Correct Answer (%) Light is more than vision non-visual / non-image forming light effects Light can be «seen» without conscious vision «Forced choice» test in a totally blind person 100 * Wavelength (nm) Nach Zaidi et al., Curr Biol, 2007
9 Non-classical Photoreceptor intrinsic photosensitive retinal ganglion cells (iprgs, Melanopsin) SCN (circadian Pacemaker) Eye A dual sensory organ Rods Retina Cones Hattar et al. Science, 2002 Berson et al. Science, 2002
10 Phase shift (h) Light and circadian phase Phase-Response Curve Initial Phase (time relative to DLMO=0) 75 % of the resetting response 6.7 hours lux polychromatic white Retina light 6.5 hours blue light (480 nm) 11.8 μwcm 2, 11.2 lux) Khalsa, et al., J Physiol (London) 2003 Rüger, et al., J Physiol (London) 2013
11 Relative Contribution Relative Contribution Why is this relevant: Light bulb versus LED Wavelength (nm) Wavelength (nm)
12 Smartphone use in adolescents (14-20 years) Use of smartphones 1 hour prior bedtime Where do you keep your smartphone during night? 99 % Ja nicht beantwortet 23% 14% irgendwo in der Wohnung irgendwo im Zimmer auf dem Nachttisch 99% yes 60% im Bett nicht beantwortet 97% in bedroom How often do you use your smartphone after «Lights off» 49% 10% 25% 15% nie selten gelegentlich häufig nicht beantwortet Strube et al. Somnologie, % occasionally-often
13 Light has also «non-circadian» acute effects Light suppresses the soporific hormone melatonin within minutes (Gronfier et al., 2002) Light inhibits sleep-promoting GABA neurons in the ventrolateral preoptic area in the hypothalamus (VLPO, Tsai et al., 2009) Light activates wake-promoting orexin neurons in the lateral hypothalamus (McGregor et al., 2011)
14 Sleep Response (min) Acute sleep induction by light in nocturnal mice 60 Lights ON Lights OFF Wildtype Melanopsin knockout 30 Melanopsin adta Time elapsed from light onset (h) According to Muindi et al., Front Syst Neurosci, 2014
15 more alert Acute alerting effects of light in diurnal humans Subjective Alertness lux! Illuminance (lux) Cajochen et al., Beh Brain Res. 2000
16 Karolinska Sleepiness Scale (KSS) % Sleepiness Change 0 = pre-light Karolinska Sleepiness Scale (KSS) The human alerting response to light is blue-shifted Monochromatic light Energy Saving Lamps Computer Screens Cajochen et al., Sleepiness and human impact assessment Book chapter, Springer, 2014
17 slower Relative Reaction Time (%) faster Baseline Dark Adaptation Sustained Attention and Response Control (Go/noGo Task) Letter W : go Letter M : no-go LED Screen Non-LED Screen Monitor: F 1,11 =12.2; p<0.04 Time of day: F 11,44 =7.8; p<0.02 Monitor x Time: F 12,132 =3.0; p= :15 19:15 20:15 21:15 22:15 23:15 00:15 Time of Day (h) * * * P <0.05 Cajochen et al., J Appl Physiol. 2011
18 % Declarative Learning (Word pairs) Correctly identified old word pairs Correctly identified new word pairs * LED Screen Non-LED * P <0.05 Cajochen et al., J Appl Physiol. 2011
19 Light is not just for vision Cortex Thalamus Hypothalamus Brainstem - Locus coeruleus Limbic system - Amygdala - Hippocampus Modified from Vandewalle et al. Trends Cogn Sci, 2009
20 Light has many non-visual biological effects in humans (only peer reviewed data) Synchronization of circadian rhythms Suppression of the «darkness hormone» melatonin Alerting and enhancing of cognitive performance Regulation of pupil size Enhancing mood (antidepressant) Enhancing physical performance in top athletes Light color modulates mental effort
21 Conclusion Light rules our body via its non-visual effects Blue wavelengths -- which are beneficial during daylight hours because they boost attention, reaction times, mood, and physical performance -- are most disruptive at night The proliferation of electronics with screens, as well as energy-efficient lighting, is increasing our exposure to blue wavelengths, especially after sundown
22 Non-visual lighting solutions should be: Dynamic Intensity and duration Spectral composition According to time of day Individual Age Gender Chronotype (early vs.late people)
23 Wanted Intelligent human centric lighting to adapt our illuminated surroundings such that we do not jeopardize quality of life and health but positively influence our sleep, circadian physiology, cognition and well-being Human Centric Lighting the room by enter Human centric lighting supports your health and promotes
24 Centre for Chronobiology Acknowledgements Antoine Viola, PhD Christina Schmidt, PhD Mirjam Münch, PhD Sarah Chellappa, PhD Vivien Bromundt, PhD Jakub Späti, PhD Sylvia Frey, PhD Virginie Gabel Micheline Maire Carolin Reichert Stephanie van der Lely Swiss Federal Office for Public Health Daimler-Benz Foundation EU IP
Effects of light on human circadian rhythms, sleep and cognition
Effects of light on human circadian rhythms, sleep and cognition Christian Cajochen Centre for Chronobiology Psychiatric Hospital of the University of Basel Basel, Switzerland 17.12.214, Tel Aviv, Israel
More informationCircadian photoreception in humans: More than meets the eye
DAYLIGHTING (4.430) MIT Architecture Circadian photoreception in humans: More than meets the eye Steven W. Lockley, Ph.D. Division of Sleep Medicine, Brigham and Women s Hospital, Boston, MA Division of
More informationRodney Heller LC, CLEP Senior Lighting Designer & Lighting Evangelist Energy Performance Lighting Cottage Grove, WI
Rodney Heller LC, CLEP Senior Lighting Designer & Lighting Evangelist Energy Performance Lighting Cottage Grove, WI Not promoting any product or manufacturer Based on existing body of research & my experience
More informationNonvisual effects of light. Prof. Grega Bizjak, PhD Laboratory of Lighting and Photometry Faculty of Electrical Engineering University of Ljubljana
Nonvisual effects of light Prof. Grega Bizjak, PhD Laboratory of Lighting and Photometry Faculty of Electrical Engineering University of Ljubljana Visual and nonvisual effects of light MIND VISION HEALTH
More informationCHAPTER 7. Can light make us bright? Effects of light on cognition sleep
3/11 Time:20:33:12 G. Kerkhof and H. P. A. Van Dongen (Eds.) Progress in Brain Research, Vol. 190 ISSN: 0079-6123 Copyright Ó 2011 Elsevier B.V. All rights reserved. CHAPTER 7 Au2 Can light make us bright?
More informationLight and the circadian clock : effects on human health
Light and the circadian clock : effects on human health Claude Gronfier, Ph.D. Département de Chronobiologie Inserm U846, Institut Cellule Souche et Cerveau Lyon, France Colloque Eclairage et Santé Association
More informationCP116. Mixed-Color LED Lighting with Circadian Benefits
Mixed-Color LED Lighting with Circadian Benefits Y. J. Tam, V. Kalavally, J. Parkkinen Department of Electrical and Computer Systems Engineering, School of Engineering, Monash University, Jalan Lagoon
More informationSleep-Wake Cycle I Brain Rhythms. Reading: BCP Chapter 19
Sleep-Wake Cycle I Brain Rhythms Reading: BCP Chapter 19 Brain Rhythms and Sleep Earth has a rhythmic environment. For example, day and night cycle back and forth, tides ebb and flow and temperature varies
More informationHuman Centric Lighting
Human Centric Lighting Daylight Related Metrics as prerequisite for assessment of light quality and for lighting design Dieter Lang OSRAM GmbH Light Affects Humans Light is Vision Brightness Information
More informationHuman Centric Lighting needs new quantities for light intensity
Human Centric Lighting needs new quantities for light intensity Luc Schlangen Lighting Europe / Philips Lighting Research Light + Building, Frankfurt, March 15 th 2016 Luc.Schlangen@Philips.com Light for
More informationLIGHT Feeling healthy,
Performance Anti jet lag Sleep Energy LIGHT Feeling healthy, energized and fit. Chrono Eyewear BV Saal van Zwanenbergweg 11 5026 RM Tilburg The Netherlands info@propeaq.com Propeaq light therapy glasses
More informationAcute exposure to evening blue-enriched light impacts on human sleep
J Sleep Res. (2013) 22, 573 580 Evening light alters sleep Acute exposure to evening blue-enriched light impacts on human sleep SARAH L. CHELLAPPA 1,2, ROLAND STEINER 3, PETER OELHAFEN 3,DIETER LANG 4,
More informationLIGHTING: THE WAY TO HEALTH & PRODUCTIVITY
LIGHTING: THE WAY TO HEALTH & PRODUCTIVITY Executive Summary Lighting: The Way to Health & Productivity Scientific research has proven the importance of light for enhancing human health as well as its
More informationLESSON 4.5 WORKBOOK How do circuits regulate their output?
DEFINITIONS OF TERMS Homeostasis tendency to relatively stable equilibrium. Feed-forward inhibition control mechanism whereby the output of one pathway inhibits the activity of another pathway. Negative
More informationLight Therapy in Sleep Disorders 2014
Light Therapy in Sleep Disorders 2014 Andrew G Veale Light and Health Effects through the eye Effects through the skin Positive effects Mood Vitality Alertess Light on skin Vitamin D production light therapy
More informationTaking the Obesity and Diabetes Risk out of Light at Night
Taking the Obesity and Diabetes Risk out of Light at Night Martin Moore-Ede, M.D., Ph.D. CIRCADIAN Light 1980 Discovery: Location of the Human Circadian Clock 2001 Discovery: Blue Light regulates Circadian
More informationLighting and health Dr Paul Littlefair Building Technology Group 8 September Part of the BRE Trust
Lighting and health Dr Paul Littlefair Building Technology Group 8 September 2017 Part of the BRE Trust Lighting in the headlines Energy-efficient CFL bulbs cause skin damage, say researchers Compact fluorescent
More informationIndex. sleep.theclinics.com. Note: Page numbers of article titles are in boldface type.
Note: Page numbers of article titles are in boldface type. A Accidents, at work, effect of shift work disorder on, 263 264 Acetylcholine, in circadian rhythms, 100 105 Acrophase, definition of, 301 Actigraphy,
More informationforming (NIF) responses of light
Quantifying non-image forming (NIF) responses of light Petteri Teikari, 21.02.2008 S-108.4010 Licentiate course in measurement science and technology CONTENTS: 1. Introduction 2. Physiology 3. Measuring
More informationTranscription Regulation And Gene Expression in Eukaryotes (Cycle G2 # )
Transcription Regulation And Gene Expression in Eukaryotes (Cycle G2 #13709-01) CIRCADIAN SIGNALING NETWORKS RG. Clerc May 19. 2010 www.fmi.ch/training/teaching Circadian rythms : most physiological processes
More informationModifiers and Retransmitters (Secondary Light Sources)
Vision and Light Vision Generators Transmitters (Light Sources) Modifiers and Retransmitters (Secondary Light Sources) Receivers Decoder Encoders Interpreter (Eyes) (Brain) Sun, Discharge lamps, fluorescent
More informationSLEEP DISORDERS IN HUNTINGTON S DISEASE. Gary L. Dunbar, Ph.D.
SLEEP DISORDERS IN HUNTINGTON S DISEASE Gary L. Dunbar, Ph.D. Executive Director, Field Neurosciences Institute Co-Director, Program in Neuroscience Central Michigan University Pre-Talk Test 1. Which type
More informationVisual System. By: Jordan Koehling
Visual System By: Jordan Koehling What is the Visual System Photoreceptors are the type of sensory neuron involved in sight. It is part of the CNS and allows us to see our surroundings using visual light
More informationLight as a central modulator of circadian rhythms, sleep and affect
Light as a central modulator of circadian rhythms, sleep and affect Tara A. LeGates 1,2, Diego C. Fernandez 1 and Samer Hattar 1,3 Abstract Light has profoundly influenced the evolution of life on earth.
More informationTHE (HIDDEN ) BENEFITS OF DAYLIGHTING
THE (HIDDEN ) BENEFITS OF DAYLIGHTING By: Eloïse Sok Abstract / Summary: This white paper aims at providing an overall understanding of the benefits of natural light on people s health and well-being,
More informationCircadian Rhythm Disturbances: What Happens When Your Biological Clock Is In The Wrong Time Zone
Circadian Rhythm Disturbances: What Happens When Your Biological Clock Is In The Wrong Time Zone Steven A. Thau MD Chief, Pulmonary, Sleep Department. Phelps Hospital, Northwell Health Internal Clock Examples
More informationEffects of Screen Light Filtering Software on Sleep and Morning Alertness
Central Washington University ScholarWorks@CWU All Master's Theses Master's Theses Winter 2017 Effects of Screen Light Filtering Software on Sleep and Morning Alertness HengYu Chi chij@cwu.edu Follow this
More informationHUMAN CENTRIC LIGHTING. System overview
HUMAN CENTRIC LIGHTING System overview Human Centric Lighting healthy light for the whole day Light affects our well-being, frames our day and night rhythm, and improves our ability to concentrate. "Human
More informationSleep, Dreaming and Circadian Rhythms
Sleep, Dreaming and Circadian Rhythms People typically sleep about 8 hours per day, and spend 16 hours awake. Most people sleep over 175,000 hours in their lifetime. The vast amount of time spent sleeping
More informationBiological Clocks. Lu Chen, Ph.D. MCB, UC Berkeley. Why Does Melatonin Now Outsell Vitamin C??
Biological Clocks Lu Chen, Ph.D. MCB, UC Berkeley 1 Why Does Melatonin Now Outsell Vitamin C?? Wake / sleep complaints are extremely prevalent. Much melatonin is consumed in an attempt to overcome the
More informationFrom Light to Cancer A discussion of recent research and its implications
From Light to Cancer A discussion of recent research and its implications By David M. Keith, FIES Introduction Recent research into the relationships between light, the human diurnal cycle and cancer have
More informationDr. Joan Saary, MD, MSc, PhD, FRCPC, CIP, FACOEM Assistant Professor of Medicine, University of Toronto OEMAC Conference, Toronto, Sept 28, 2015
Dr. Joan Saary, MD, MSc, PhD, FRCPC, CIP, FACOEM Assistant Professor of Medicine, University of Toronto OEMAC Conference, Toronto, Sept 28, 2015 DISCLOSURE OF COMMERCIAL SUPPORT Potential for conflict(s)
More informationPediatrics Grand Rounds 16 July University of Texas Health Science Center at San Antonio
Light Pollution and Melatonin Suppression: Implications for Pediatrics Russel J. Reiter University of Texas Health Science Center San Antonio, Texas reiter@uthscsa.edu Evolution has dictated biological
More informationTechnology s Impact on Healthy Sleep
Technology s Impact on Healthy Sleep JEFFREY S. DURMER, MD, PHD Adjunct Professor, Georgia State Univ. Chief Medical Officer, FusionHealth, Atlanta, GA Agenda How Technology Detracts from Your Sleep How
More informationHuman nonvisual responses to light crucially rely on
JCEM ONLINE Brief Report Endocrine Research Human Melatonin and Alerting Response to Blue-Enriched Light Depend on a Polymorphism in the Clock Gene PER3 Sarah L. Chellappa, Antoine U. Viola, Christina
More informationLecture 8. Arousal & Sleep. Cogs17 * UCSD
Lecture 8 Arousal & Sleep Cogs17 * UCSD Arousal in the Brain Stimulated by sensory input Initiated, maintained endogenously Basal Forebrain Delivers ACh throughout cortex Arousal in the Brain Lateral Hypothalamus
More information2. METHODS. 2.1 Apparatus
Pupillary light reflex associated with melanopsin and cone photorecetors Sei-ichi Tsujimura, 1 Katsunori Okajima, 2 1 Faculty of Sciences and Engineering, Kagoshima University, Japan 2 Faculty of Environment
More informationBiological Clocks. Lu Chen, Ph.D. MCB, UC Berkeley. What is biological clock?
Biological Clocks Lu Chen, Ph.D. MCB, UC Berkeley 1 What is biological clock? All eukaryotes and some prokaryotes display changes in gene activity, biochemistry, physiology, and behavior that wax and wane
More informationPHYSIOLOGY AND MAINTENANCE Vol. V - Biological Rhythms - Tarja Porkka-Heiskanen, Jarmo T. Laitinen
BIOLOGICAL RHYTHMS Tarja Porkka-Heiskanen, Institute of Biomedicine, University of Helsinki, Finland Jarmo T. Laitinen Department of Physiology, University of Kuopio, Finland Keywords: Light, melatonin,
More informationLight, body clocks and sleep - SE13
Light, body clocks and sleep - SE13 Friday 4th January 2013 10:15-11:00 Location: Palmer, 109 Russell G. Foster FRS Professor of Circadian Neuroscience Head, Nuffield Laboratory of Ophthalmology Fellow,
More informationThe Use of Bright Light in the Treatment of Insomnia
Chapter e39 The Use of Bright Light in the Treatment of Insomnia Leon Lack and Helen Wright Department of Psychology, Flinders University, Adelaide, South Australia PROTOCOL NAME The use of bright light
More informationUC San Diego UC San Diego Previously Published Works
UC San Diego UC San Diego Previously Published Works Title A breakthrough treatment for major depression Permalink https://escholarship.org/uc/item/83h8614r Journal Journal of Clinical Psychiatry, 76(5)
More informationLighting and Melatonin: How Lighting Impacts Melatonin Suppression and Regulation
1 Lighting and Melatonin: How Lighting Impacts Melatonin Suppression and Regulation Evan Bailey Brigham Young University Summary Melatonin has long been an important element in the function of the human
More informationSENSES: VISION. Chapter 5: Sensation AP Psychology Fall 2014
SENSES: VISION Chapter 5: Sensation AP Psychology Fall 2014 Sensation versus Perception Top-Down Processing (Perception) Cerebral cortex/ Association Areas Expectations Experiences Memories Schemas Anticipation
More informationMake sure you remember the Key Concepts
A2 Psychology Term 1 Module 4 Physiological Psychology Biological Rhythms, Sleep and Dreaming Area of Study: Biological Rhythms. Lesson 7 Getting you Thinking pg 403 Make sure you remember the Key Concepts
More information24-hr Lighting Schemes for Older Adults and Persons with Low Vision
24-hr Lighting Schemes for Older Adults and Persons with Low Vision Panel Impacts on Vision Glare, Contrast, Color Mariana G. Figueiro, PhD Associate Professor Lighting Research Center Rensselaer Polytechnic
More informationReport. Entrainment of the Human Circadian Clock to the Natural Light-Dark Cycle
Current Biology 23, 554 558, August 9, 203 ª203 Elsevier Ltd All rights reserved http://dx.doi.org/0.06/j.cub.203.06.039 Entrainment of the Human Circadian Clock to the -Dark Cycle Report Kenneth P. Wright,
More informationThe Diagnosis and Treatment of Circadian Rhythm Disorders
Adelaide Institute for Sleep Health, Repatriation General Hospital, Daw Park, SA The Diagnosis and Treatment of Circadian Rhythm Disorders Professor Leon Lack School of Psychology, Flinders University
More informationTargeting of the attenuated diphtheria toxin (adta) into the melanopsin locus. a,
doi: 1.138/nature6829 a DTA HSV- TK PGK-Neo Targeting construct b kb.85.65 L WT adta/+ adta/ adta Melanopsin (Opn 4) Genomic Locus 1 kb.4 Supplementary Figure 1: Targeting of the attenuated diphtheria
More informationCIRCADIAN SIGNALING NETWORKS
Transcription Regulation And Gene Expression in Eukaryotes Cycle G2 (lecture 13709) FS 2014 P. Matthias and RG Clerc Roger G. Clerc 07.05.2014 CIRCADIAN SIGNALING NETWORKS Master pacemaker SCN «Slave clocks»
More informationto dusk Chris Aiken, MD Instructor, Wake Forest University Dept of Psychiatry Director, Mood Treatment Center NCPA, 2018
DAWN to dusk Chris Aiken, MD Instructor, Wake Forest University Dept of Psychiatry Director, Mood Treatment Center NCPA, 2018 Disclaimer Materials that are included in this course may include interventions
More informationThe right light for health and well-being The importance of the biological effects of light and lighting concepts
The right light for health and well-being The importance of the biological effects of light and lighting concepts An introduction to the subject by LEDVANCE experts 2 Table of contents 1. INTRODUCTION...
More informationDAWN. to dusk. Chris Aiken, MD Instructor, Wake Forest University Dept of Psychiatry Director, Mood Treatment Center. Friday, September 28, 2018
Dawn to Dusk Chris Aiken, MD DAWN to dusk Chris Aiken, MD Instructor, Wake Forest University Dept of Psychiatry Director, Mood Treatment Center NCPA, 2018 Disclaimer Materials that are included in this
More informationSeeing Ultraviolet. Keeping Time with Neuropsin
Seeing Ultraviolet Keeping Time with Neuropsin Ian Ashdown, P. Eng., FIES Chief Scientist, Lighting Analysts Inc. Wordpress Blog (www.agi32.com/blog) 2015/10/26 What does it mean to see? The word is ubiquitous
More informationThe effect of light on performance
Work Smart - Feel Good The effect of light on performance The parallels between astronauts and office workers Introduction It is widely known that light has an effect on our wellbeing. In general, north
More informationProceedings EXPERIENCING LIGHT 2009 International Conference on the Effects of Light on Wellbeing
Proceedings EXPERIENCING LIGHT 2009 International Conference on the Effects of Light on Wellbeing Y. A. W. de Kort, W. A. IJsselsteijn, I. M. L. C. Vogels, M. P. J. Aarts, A. D. Tenner, & K. C. H. J. Smolders
More informationBlue Light and Digital Eye Strain
Blue Light and Digital Eye Strain Educating Patients and Providing Solutions Anne-Marie Lahr, OD Dangers of Blue Light Dangers of blue light Ocular discomfort Interruption of sleep patterns and circadian
More informationOverview of the Biology of Sleep and Circadian Rhythms
Overview of the Biology of Sleep and Circadian Rhythms Daniel J. Buysse, MD UPMC Professor of Sleep Medicine Professor of Psychiatry and Clinical and Translational Science University of Pittsburgh School
More informationThe Acute and Phase-Shifting Effects of Artificial Bright Light on Human Physiology, Performance and Symptoms of Jet-Lag.
The Acute and Phase-Shifting Effects of Artificial Bright Light on Human Physiology, Performance and Symptoms of Jet-Lag Andrew Thompson A thesis submitted in partial fulfilment of the requirements of
More informationFrom the reveller to the lark
In Focus: Chronobiology From the reveller to the lark The internal clock changes with age Prof. Dr. Anne Eckert, Neurobiological Laboratory for Brain Aging and Mental Health, Psychiatric University Clinics
More informationLED Lighting and the AMA. Dr. Ronald B. Gibbons Director Center for Infrastructure-Based Safety Systems
LED Lighting and the AMA Dr. Ronald B. Gibbons Director Center for Infrastructure-Based Safety Systems Health Impacts and Subjective Color Circadian rhythm, hormone secretion: The hormones responsible
More informationModule 1 Workbook And Sleep Challenge.
Module 1 Workbook And 10 10 Sleep Challenge. INTRODUCTION. Congratulations for completing module 1. I hope you have learned why a strong circadian rhythm is important, and what you can do to dial in your
More informationHuman Centric Lighting
Human Centric Lighting This article is based on the presentation made at the IESSA Congress in Cape Town on 15 May 2017. Introduction I was always aware of the fact that light played a significant role
More informationNovel insights into photoreception, phototransduction and biological rhythms how might this impact on carcinogenesis?
Children with Leukaemia Scientific Conference Wednesday 8 th September 2004 Novel insights into photoreception, phototransduction and biological rhythms how might this impact on carcinogenesis? Russell
More informationAIR FORCE INSTITUTE OF TECHNOLOGY
COGNITIVE EFFECTS OF SHORT DURATION SHORT WAVELENGTH VISIBLE LIGHT THESIS Sarah J. Bolton, Captain, USAF AFIT-ENG-MS-18-M-012 DEPARTMENT OF THE AIR FORCE AIR UNIVERSITY AIR FORCE INSTITUTE OF TECHNOLOGY
More informationThomas W. O Reilly, MS, PCC in cooperation with Lakeshore Educational and Counseling Services
Thomas W. O Reilly, MS, PCC in cooperation with Lakeshore Educational and Counseling Services www.lakeshoresupport.com Humans have biological rhythms, known as Circadian Rhythms (CR) CR refers to cyclical
More informationNon-Visual Effects of Light on Melatonin, Alertness and Cognitive Performance: Can Blue-Enriched Light Keep Us Alert?
Non-Visual Effects of Light on Melatonin, Alertness and Cognitive Performance: Can Blue-Enriched Light Keep Us Alert? Sarah Laxhmi Chellappa 1,2, Roland Steiner 3, Peter Blattner 4, Peter Oelhafen 3, Thomas
More informationWavelength-dependent effects of evening light exposure on sleep architecture and sleep EEG power density in men
Am J Physiol Regul Integr Comp Physiol 290: R1421 R1428, 2006. First published January 26, 2006; doi:10.1152/ajpregu.00478.2005. Wavelength-dependent effects of evening light exposure on sleep architecture
More informationDEGREE (if applicable)
OMB No. 0925-0001/0002 (Rev. 08/12 Approved Through 8/31/2015) NAME: Eastman, Charmane I. BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors.
More informationDark and light adaptation: a job that is accomplished mainly in the retina
Dark and light adaptation: a job that is accomplished mainly in the retina Dark adaptation: recovery in darkness (of sensitivity) and photoreceptor pigment. Light adaptation: The ability of the visual
More informationEEG Sleep Circadian rhythms Learning Objectives: 121, 122
EEG Sleep Circadian rhythms Learning Objectives: 121, 122 Zoltán Lelkes Electroencenphalography Hans Berger pen time amplifier electrodes 1 The waves of the EEG gamma > 30 Hz beta: 13-30 Hz Mental activity:
More informationShort Blue Light Pulses (30 Min) in the Morning Support a Sleep-Advancing Protocol in a Home Setting
657462JBRXXX10.1177/0748730416657462Journal of Biological RhythmsGeerdink et al. / Short Blue Light Pulses in the Morning research-article2016 Short Blue Light Pulses (30 Min) in the Morning Support a
More informationMelanopsin, photosensitive ganglion cells, and seasonal affective disorder.
Thomas Jefferson University Jefferson Digital Commons Department of Neurology Faculty Papers Department of Neurology 3-1-2013 Melanopsin, photosensitive ganglion cells, and seasonal affective disorder.
More informationTHE VISUAL WORLD! Visual (Electromagnetic) Stimulus
THE VISUAL WORLD! Visual (Electromagnetic) Stimulus Perceived color of light is determined by 3 characteristics (properties of electromagnetic energy): 1. : the spectrum (wavelength) of light (color) 2.
More informationWhat do we perceive?
THE VISUAL SYSTEM Aditi Majumder What do we perceive? Example: Switch off the light in room What we perceive Not only the property of the scene But also that of the visual system Our perception is filtered
More informationKent Academic Repository
Kent Academic Repository Full text document (pdf) Citation for published version Bossi, Arthur and Hopker, James G. (2016) Twilight: filter the blue light of your device and sleep better. British Journal
More informationNIH Public Access Author Manuscript Curr Biol. Author manuscript; available in PMC 2014 August 19.
NIH Public Access Author Manuscript Published in final edited form as: Curr Biol. 2013 August 19; 23(16): 1554 1558. doi:10.1016/j.cub.2013.06.039. Entrainment of the Human Circadian Clock to the Natural
More informationSleep Biology: Circadian Rhythms and Mother Nature
Sleep Biology: Circadian Rhythms and Mother Nature Paula Carvalho, MD, FCCP Professor of Medicine Pulmonary and Critical Care Medicine University of Washington and Academic Section Head, Pulmonary /MICU
More informationBiological Rhythms, Sleep, and Dreaming. Elaine M. Hull
Biological Rhythms, Sleep, and Dreaming Elaine M. Hull Rhythms of Waking and Sleeping Animals generate 24 hour cycles of wakefulness and sleep. Some animals generate endogenous circannual rhythms (yearly
More informationNews Focus. What s. Color. in a. The Unique Human Health Effects of Blue Light
News Focus What s in a Color? The Unique Human Health Effects of Blue Light Ron Sutherland/Photo Researchers, Inc In 1958, J. Woodland Hastings and Beatrice M. Sweeney tested the ability of different wavelengths
More informationHomeostatic and Circadian Regulation of the Sleep-Wake Cycle
Homeostatic and Circadian Regulation of the Sleep-Wake Cycle Derk-Jan Dijk, PhD, FRSB Professor of Sleep and Physiology Presentation for International Sleep Medicine Course Cardiff 6-9 June 216 Monday,
More informationPsy393: Cognitive Neuroscience. Prof. Anderson Department of Psychology Week 3
Psy393: Cognitive Neuroscience Prof. Anderson Department of Psychology Week 3 The Eye: Proof for the existence of God? And then there was light Optics Perception Absorption Eye is receiver not sender Plato
More informationNEURAL MECHANISMS OF SLEEP (p.1) (Rev. 3/21/07)
NEURAL MECHANISMS OF SLEEP (p.1) (Rev. 3/21/07) 1. Revisitation of Bremer s 1936 Isolated Brain Studies Transected the brain: a. Cut between the medulla and the spinal cord ( encephale isole ) Note: recall
More informationNIH Public Access Author Manuscript Neuro Endocrinol Lett. Author manuscript; available in PMC 2012 May 10.
NIH Public Access Author Manuscript Published in final edited form as: Neuro Endocrinol Lett. 2010 ; 31(1): 92 96. Lack of short-wavelength light during the school day delays dim light melatonin onset
More informationSuperCharged Step 4 Circadian Rhythms, Light and Sleep
SuperCharged Step 4 Circadian Rhythms, Light and Sleep Sleep is critical to optimal health, daily functioning, and mental well being. You know that. And you know you probably need more sleep than you get.
More informationSleep & Well-being. Neuroscience of Sleep & Clocks Impact of Sleep Disruption Sleep in the Young Sleep Hygiene Mental Illness Discussion
Sleep & Well-being Neuroscience of Sleep & Clocks Impact of Sleep Disruption Sleep in the Young Sleep Hygiene Mental Illness Discussion http://www.eye.ox.ac.uk/research/sleepcircadian-neuroscience-institute
More information****REVISED 4/27/2015****
Exam 2 Study Guide Disclaimer: This is intended as a study aid. It is not a complete description of everything discussed in class, nor an exhaustive list of information that might be tested on an exam.
More informationVisual and non-visual Effects of Light
Visual and non-visual Effects of Light Prof. Grega Bizjak, PhD Laboratory of Lighting and Photometry Faculty of Electrical Engineering University of Ljubljana Light is life If sun would turn off the life
More informationPhase advancing the human circadian clock with blue-enriched polychromatic light
Sleep Medicine (9) 87 94 Original Article Phase advancing the human circadian clock with blue-enriched polychromatic light Mark R. Smith a,b, Victoria L. Revell c, Charmane I. Eastman a,b, * a Biological
More informationEVALUATION OF SLEEP IN INDIVIDUALS WITH GLAUCOMA By: Dana Bakir M.Sc. Candidate Supervised by: Dr. Olga Overbury and Dr.
EVALUATION OF SLEEP IN INDIVIDUALS WITH GLAUCOMA By: Dana Bakir M.Sc. Candidate Supervised by: Dr. Olga Overbury and Dr. Caitlin Murphy SCHOOL OF OPTOMETRY, UNIVERSITY OF MONTREAL Sleep Sleep is controlled
More informationPROGRAM: SLTBR Meeting Location: Centre Mont-Royal, 2200 rue Mansfield, Montréal, H3A 3R8
PROGRAM: SLTBR Meeting 2011 July 10 th 13 th, Montréal, Canada Location: Centre Mont-Royal, 2200 rue Mansfield, Montréal, H3A 3R8 Sunday, July 10th, 2011 15:30-17:30 SLTBR Board Meeting 19:00-21:00 Welcome
More informationCephalization. Nervous Systems Chapter 49 11/10/2013. Nervous systems consist of circuits of neurons and supporting cells
Nervous Systems Chapter 49 Cephalization Nervous systems consist of circuits of neurons and supporting cells Nervous system organization usually correlates with lifestyle Organization of the vertebrate
More informationlet's continue talking about the eye,
Eye is mainly composed of 3 layers: External layer, which called The Sclera which is a hard connective tissue that gives the eye its round shape. Extension of the sclera into the front is the cornea, which
More informationDr Alex Bartle. Medical Director Sleep Well Clinic Christchurch
Dr Alex Bartle Medical Director Sleep Well Clinic Christchurch 11:00-11:55 WS #113: Circadian Sleep Disorders 12:05-13:00 WS #125: Circadian Sleep Disorders (Repeated) Overview The Structure of Sleep
More information3.4 Photoisomerization reactions
3.4 Photoisomerization reactions A photoisomerization is the conversion of one isomer into another isomer by light. The examples we will look at involve exclusively the conversion between two geometric
More informationShiftwork and Fatigue: Understanding the Human Machine. Andrew Moore-Ede Director of Client Services
Shiftwork and Fatigue: Understanding the Human Machine Andrew Moore-Ede Director of Client Services HUMAN DESIGN SPECS The Biological Clock (SCN) & Circadian Rhythms Hypothalamus Cortex SCN Eye Pituitary
More informationSENIOR LIVING LIGHTING SOLUTIONS FOR RESIDENTS & STAFF. Improving Health, Wellbeing, Safety & Staff Productivity
SENIOR LIVING LIGHTING SOLUTIONS FOR RESIDENTS & STAFF Improving Health, Wellbeing, Safety & Staff Productivity SENIOR LIVING LIGHTING SOLUTIONS FOR RESIDENTS & STAFF Improving Health, Wellbeing, Safety,
More informationTHE VISUAL WORLD! Visual (Electromagnetic) Stimulus
THE VISUAL WORLD! Visual (Electromagnetic) Stimulus Perceived color of light is determined by 3 characteristics (properties of electromagnetic energy): 1. Hue: the spectrum (wavelength) of light (color)
More informationTest of visual pathway function
The visual system Test of visual pathway function Suppose you have a patient who may have some damage to the visual pathways leading to visual cortex, for example from multiple sclerosis. How could you
More informationNew PI-LED technology for atmospheric and authentic Illumination of old buildings
New PI-LED technology for atmospheric and authentic Illumination of old buildings Univ.Prof.Dr. Günther Leising Graz University of Technology, Austria LUMITECH Produktion und Entwicklungs GmbH, Jennersdorf,
More information