Physician s Reference for Urine and Blood Drug Testing and Interpretation

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1 Physician s Reference for Urine and Blood Drug Testing and Interpretation

2 DETECTIMED PANEL Urine (test code 70195) Screen Confirmation Screen Confirmation Alcohol Ethanol Amphetamines Amphetamine Methamphetamine MDMA Barbiturates Butalbital Phenobarbital Benzodiazepines 7-Aminoclonazepam Alpha-hydroxyalprazolam Alprazolam Lorazepam Nordiazepam Oxazepam Temazepam Buprenorphine Buprenorphine Norbuprenorphine Cannabinoids THC-COOH Cocaine Benzoylecgonine Fentanyl Fentanyl Norfentanyl 0.02% (w/v) 500 ng/ml 200 ng/ml 75 ng/ml 5 ng/ml 20 ng/ml 1 2 ng/ml 0.02% (w/v) 2 ng/ml 10 ng/ml 5 ng/ml 30 ng/ml 0.5 ng/ml 0.5 ng/ml Methadone Methadone EDDP Opiates 6-MAM Codeine Hydrocodone Hydromorphone Morphine Oxycodone Oxymorphone Propoxyphene Norpropoxyphene Soma Carisoprodol Meprobamate Tramadol Tramadol Nortramadol 300 ng/ml 0.1 µg/ml 200 ng/ml Acetaminophen 10 µg/ml N/A Specimen Validity 20 ng/ml 2.5 µg/ml 2.5 µg/ml 125 ng/ml 125 ng/ml Creatinine >5 mg/dl (normal) General Oxidants 200 µg/ml ph (normal) Specific Gravity* (normal) Specimen Requires: 20mL urine Transport: Ambient Temperature Reported: as little as 72 hours *Specific gravity is measured only if Creatinine is <5 mg/dl.

3 DRUGS KNOWN TO YIELD FALSE POSITIVE IMMUNOASSAY SCREENING RESULTS Generic Name Alternate Names Generic Name Alternate Names AMPHETAMINES Amantadine Bupropion Chloroquine Chlorpromazine Desipramine Dextroamphetamine Ephedrine Fenfluramine Labetalol Mexiletine Procainamide Phentermine Phenylephrine Propranolol Pseudoephedrine Quinacrine Rantidine Selegiline Trazadone BARBITURATES Phenytoin Primidone BENZODIAZEPINES Oxaprozin Sertraline Amantadine Wellbutrin /Zyban Aralen Thorazine Norpramine Dexedrine Ephedra/Ma Huang Fen Phen Labetalol Mexitil Procainamide Adipex Neo-Synephrine Inderal Claritin-D /Sudafed Atabrine/Mepacrine Zantac Deprenyl Desyrel Dilantin Mysoline Daypro Zoloft CANNABINOIDS Efavirenz Hemp Seed Oil Pantoprazole OPIATES Fluroquinolones Ofloxacin Papaverine Rifampin OXYCODONE Hydrocodone Hydromorphone Oxymorphone Codeine * This is an annotated list. TRUE POSITIVES FROM ALTERNATIVE SOURCES Sustiva Cannabis Seed/Hemp Oil Protonix Levaquin Floxin Papaverine Rimactane Vicodin Dilaudid Numorphan Codeine Cannabinoids: Dronabinol/Marinol contains the same active ingredients as marijuana. Testing is not able to distinguish between prescription and illicit use. Opiates: Poppy seeds contain morphine. Testing is not able to distinguish between poppy seeds and prescription origin.

4 DETECTION WINDOWS Substances Blood Urine Acetaminophen 1 10 hours 1 2 days Amphetamines 1 5 days 1 5 days Amphetamine, Methamphetamine, MDMA Barbiturates 1 30 days Short-Acting: 1 3 days Pentobarbital, Secobarbital Intermediate-Acting: 1 5 days Amobarbital, Butabarbital, Butalbital Long-Acting: 1 30 days Phenobarbital Benzodiazepines 1 6 days 1 10 days Chlordiazepoxide (Librium ), Alprazolam (Xanax ), Alpha-hydroxyalprazolam, Diazepam (Valium), Lorazepam (Ativan ), Nordiazepam (Madar), Oxazepam (Serax ), Temazepam (Restoril ), Clonazepam (Klonopin ), 7-Aminoclonazepam Substances Blood Urine Buprenorphine/ Norbuprenorphine 1 10 days 1 10 days Cannabinoids (Marijuana) THC, THC-COOH Occasional User: 1 3 days 1 4 days Frequent User: 1 14 days 1 30 days Cocaine 1 8 hours 1 4 days Cocaine, Benzoylecgonine, Cocaethylene Ethanol (Alcohol) Eliminate 1 24 hours 1 drink/hour Ethyl Glucuronide N/A 1 3 days Fentanyl/Norfentanyl 1 2 days 1 4 days Gabapentin (Neurontin ) 1 48 hours 1 4 days Methadone/EDDP 1 10 days 1 10 days Opiates 1 24 hours 1 4 days Codeine, 6-MAM (Heroin marker), Morphine, Hydrocodone, Hydromorphone, Oxycodone, Oxymorphone continued

5 DETECTION WINDOWS continued COMMON TEST CODES Substances Blood Urine AIT Test Code Test Name / Alternate Name Phentermine 1 4 days 1 4 days Pregabalin (Lyrica ) 1 4 days 1 4 days Propoxyphene/ 1 5 days 1 5 days Norpropoxyphene Soma Carisoprodol 1 10 hours 1 2 days Meprobamate 1 3 days 1 4 days Tapentadol (Nucynta ) N/A 1 2 days Tramadol/Nortramadol 1 24 hours 1 4 days DetectiMed Panel, Urine / Comprehensive Panel DetectiMed Panel, Blood / Comprehensive Panel Tapentadol, Urine / Nucynta (and metabolite) Duloxetine, Urine Ethyl Glucuronide, Urine / Ethanol (metabolite) Phentermine (confirmation), Urine / Adipex-P, Fastin, Ionamin Pregabalin, Urine / Lyrica Amitriptyline, Urine / Nortriptyline Promethazine (confirmation), Blood / Phenergan Methylphenidate, Urine / Concerta, Metadate, Ritalin Zolpidem, Blood / Ambien SelectiMed Panel, Urine / Limited Panel NOTE: Detection windows are approximate values that depend upon the nature of the drug, individual metabolism, dosage, and dosage forms. A complete test catalog is available at

6 METABOLISM OF OPIOIDS Heroin Morphine Tramadol Fentanyl Codeine 6-MAM Nortramadol Norfentanyl Hydrocodone (Vicodin) Oxycodone (Oxycontin, Percocet) Buprenorphine Methadone Hydromorphone (Dilaudid) Oxymorphone (Numorphan, Opana) Norbuprenorphine EDDP Known metabolites Patterns observed in patients receiving chronic opiate therapy

7 METABOLISM BENZODIAZEPINES Clorazepate (Tranxene) Alprazolam (Xanax) Clonazepam (Klonopin) Chlordiazepoxide (Librium) Halazepam (Paxipam) Alpha-hydroxyalprazolam 7-Aminoclonazepam Nordiazepam Lorazepam (Ativan) Triazolam (Halcion) Diazepam (Valium) Temazepam (Restoril) Oxazepam (Serax)

8 CONTACT INFORMATION Client Services The direct line to AIT Laboratories is Please ask for CLIENT SERVICES, as they can answer the majority of your questions or direct you to the appropriate person or department when further assistance is required. Contact the department about your account between 8 a.m. and 8 p.m. (EST) Monday through Friday. You may also our Client Services Department at UPS Phone: NOTE: When scheduling a pick-up with a UPS agent, please use this phrase: I am scheduling a Next Day Air Return Services Pick-Up. Please provide a pick-up time for specimens along with your facility s closing time. Billing Sales Your account executive: Phone number: Your regional sales manager: Phone number: Questions for our Billing Department? Call the direct line and ask to speak with our client relations specialist. You can also your questions anytime to BillingEdits@AITLabs.com or send a fax to Toxicologists AIT s team of expert toxicologists can help you apply theoretical concepts to real-world scenarios. Need answers now? Call us at or send an to Toxicologist@AITLabs.com.

9 2265 Executive Drive, Indianapolis, Indiana fax AITLABS.com follow SMR086 Effective Date: 08/19/2011

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