Schedule of Accreditation issued by United Kingdom Accreditation Service 2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK

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1 Schedule of ccreditation United Kingdom ccreditation Service 2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK ccredited to Laboratory locations: Gavenny Court Brecon Road bergavenny Monmouthshire NP7 7RX Contact: Quality Manager Tel: +44 (0) Fax: +44 (0) labservices.info@synlabuk.com below s covered by the organisation and their relevant activities details ctivity code ddress Gavenny Court Brecon Road bergavenny Monmouthshire NP7 7RX Local contact Quality Manager Tel: +44 (0) Fax: +44 (0) labservices.info@synlabuk.com Drugs of abuse analysis Quality Management Site activities performed away from the locations listed above: details ctivity code Commercial premises, Offices Local contact Quality Manager Specimen collection ( Hair, Saliva, Urine) B Tel: +44 (0) Fax: +44 (0) labservices.info@synlabuk.com ssessment Manager: HM1 Page 1 of 11

2 Schedule of ccreditation United Kingdom ccreditation Service ccredited to DETIL OF CCREDITTION BODY FLUIDS, HIR ND PLSM Documented In-house Method Hair Presumptive Screening for Screening method using ELIS (enzyme immunoassay) mphetamines Benzoylecgonine, Cannabis, Barbiturates, Benzodiazepines, Opiates Ketamine, Phencyclidine, Method Oral fluid extracted from Quantisal collection kit Presumptive Screening for Screening method using CEDI immunoassay mphetamines Benzoylecgonine Cannabis Barbiturates, Benzodiazepines Opiates Method Method Method Method Method Method Method Urine Presumptive Screening for Screening method using DRI assay lcohol Method Urine dulteration tests: Creatinine ph Specific Gravity Method using colourimetry Method using colourimetry Method using colourimetry ssessment Manager: HM Page 2 of 11

3 Schedule of ccreditation United Kingdom ccreditation Service ccredited to BODY FLUIDS, HIR ND PLSM Documented In-house Method Urine Presumptive screening for: using CEDI Immunoassay mphetamines Barbiturates Benzodiazepines Benzoylecogonine Buprenorphine Cannabis metabolites 6 Mono acetyl morphine Propoxyphene Phencyclidine (PCP) Opiates Methaqualone Presumptive screening for ethyl glucuronide (ethanol indicator and not as marker for alcohol abuse ) Presumptive screening for Ketamine Presumptive screening for Tramadol Presumptive screening for Lysergic acid diethylamide (LSD) Method Method Method Method Method Method Method Method Method Method Method Method Method using DRI Immunoassay Method DRI Immunoassay Method using Immunalysis Immunoassay Method using ELIS immunoassay ssessment Manager: HM Page 3 of 11

4 Schedule of ccreditation United Kingdom ccreditation Service ccredited to BODY FLUIDS ND TISSUES Documented In-House Methods using Urine of: mphetamine Benzoylecgonine 2-ethylidene-1,5-dimethyl-3,3- diphenylpyrrolidine (EDDP) 3,4-Methylenedioxyamphetamine (MD) 3,4-Methylenedioxy-Nethylamphetamine(MDE) 3,4-methylenedioxymeth amphetamine (MDM) Methamphetamine Method using solid phase extraction and LCMSMS Barbiturates: mylobarbital Butabarbital Pentobarbital Phenobarbital Secobarbital Method using Solid Phase extraction followed by LCMSMS Benzodiazepines: 7 amino nitrazepam 7 amino flunitrazepam Desmethyl Diazepam Diazepam Flunitrazepam Oxazepam Temazepam Method using hydrolysis followed by solid phase extraction and LCMSMS Buprenorphine Norbuprenorphine Method using hydrolysis and solid Phase extraction followed by LCMSMS Ketamine, Norketamine Method using Solid Phase extraction followed by LCMSMS 6-Mono-cetyl Method using Solid Phase extraction followed by LCMSMS ssessment Manager: HM Page 4 of 11

5 Schedule of ccreditation United Kingdom ccreditation Service ccredited to BODY FLUIDS ND TISSUES Documented In-House Methods using Urine of: 11-Nor 9-Tetrahydro Cannabinol-9-Carboxylic cid Method using hydrolysis followed by solid phase extraction, and LCMSMS S-Phenyl Mercapturic cid (SPM) Method by sample dilution and LC-MS-MS Confirmation and Quantitation of Opiates: ine Dihydrocodeine Method using hydrolysis followed by solid phase extraction, and LCMSMS Confirmation only of Opiates: Desmethylpapaverine Dihydromorphine Hydrocodone Noscapine Papaverine Pholcodine Thebaine Urine (unpreserved) Screening for; mphetamines; mphetamine Method using B Sciex Triple TOF with fast chromatography MDM MDE Methamphetamine Barbiturates; Phenobarbital Secobarbital Benzodiazepines; minonitrazepam minoflunitrazepam Flunitrazepam Hydroxyalprazolam ssessment Manager: HM Page 5 of 11

6 Schedule of ccreditation United Kingdom ccreditation Service ccredited to BODY FLUIDS ND TISSUES Urine (unpreserved) Screening for ; Benzodiazepines ; Lorazepam Method using B Sciex Triple TOF with fast chromatography Nordiazepam Oxazepam Phenazepam Temazepam Cannabinoids; Cannabinol THC THCC Cocainics; Benzoylecgonine Cocaethylene Cocaine Opiates; ine DHC 6-MM Opioids; Buprenorphine EDDP Fentanyl Norpropoxyphene o-desmethyltramadol Oxycodone Oxymorphone Propoxyphene Tramadol Psychoactives; mitriptyline Dihydronorketamine Gabapentin Ketamine Methaqualone Mirtazapine Norketamine ssessment Manager: HM Page 6 of 11

7 Schedule of ccreditation United Kingdom ccreditation Service ccredited to BODY FLUIDS ND TISSUES Urine (unpreserved) Screening for ; Method using B Sciex Triple TOF with fast chromatography Psychoactives ; PCP Pregabalin Quetiapine Cathinones; Cathinone Mephedrone KEDT Plasma from Blood Confirmation and Quantitation of: Clozapine Norclozapine Method using protein precipitation and LC-MS-MS Oral fluid (extracted from Quantisal collection kit) of : mphetamines: mphetamine, Methamphetamine, MDM, MDE. Method using sample dilution in buffer and LC-MS-MS ssessment Manager: HM Page 7 of 11

8 Schedule of ccreditation United Kingdom ccreditation Service ccredited to BODY FLUIDS ND TISSUES Workplace/ Chemical Tests Documented In-house methods Oral fluid (extracted from Quantisal collection kit) of : Benzodiazepines: lprazolam, Desmethyldiazepam, Diazepam, Flunitrazepam, Lorazepam, Oxazepam, Temazepam, Method using sample dilution in buffer and LC-MS-MS Cocainics: Cocaine, Benzoylecgonine, Cocaethylene. Opiates: ine, Dihydrocodeine, 6Monoacetylmorphine, Synthetic Opioids:, EDDP. Other psychoactive substance; Ketamine, Norketamine. Mephedrone Propoxyphene, Norpropoxyphene. Tramadol ssessment Manager: HM Page 8 of 11

9 Schedule of ccreditation United Kingdom ccreditation Service ccredited to BODY FLUIDS ND TISSUES (Cont d) Documented In-house method Hair of: mphetamines: mphetamine MDM MDE Method By extraction and LC-MS-MS Benzodiazepines: Desmethyl Diazepam Diazepam Flunitrazepam Lorazepam Nitrazepam Oxazepam Temazepam Cocainics: Cocaine: Benzoylecgonine Cocaethylene Norcocaine Opiates: cetyl ine ine Dihydrocodeine 6 Monoacetyl Heroin Synthetic Opiods: Other psychoactive substance: Ketamine Nor-ketamine Mephedrone Propoxyphene, Nor-propoxyphene Tramadol Zolpidem ssessment Manager: HM Page 9 of 11

10 Schedule of ccreditation United Kingdom ccreditation Service ccredited to BODY FLUIDS ND TISSUES Chemical Tests Documented In-house method Whole Blood of drugs of abuse; mphetamine Method using LC-MS-MS Clonazepam Diazepam Flunitrazepam Ketamine Lorazepam Methamphetamine Methylenedioxymethampheta mine (ecstasy) Oxazepam Temazepam Nordiazepam Norketamine Whole Blood (Preserved) Detection and quantitation of drugs Benzoylecgonine(50 µg/l) Cocaine (10 µg/l) Delta-9-tetrahydrocannabinol (2 µg/l) Method using protein precipitation and LC-MS-MS Method using liquid extraction and LC-MS-MS Whole Blood (preserved) of drugs of abuse: mphetamine Method using LC-MS-MS Benzolyecgonine Clonazepam Cocaine Diazepam Flunitrazepam Ketamine Lorazepam Methamphetamine MDM 6-monoacetylmorphine ssessment Manager: HM Page 10 of 11

11 Schedule of ccreditation United Kingdom ccreditation Service ccredited to BODY FLUIDS ND TISSUES Chemical Tests: Documented In-house method Whole Blood (preserved) of drugs of abuse: Oxazepam Method using LC-MS-MS Temazepam Nordiazepam Norketamine Opinion and interpretation Documented In-house Methods Drugs of buse in Urine, Oral fluid (Quantisal) and Hair Opinion and interpretation; relating to consistency of results with declared medication Method opinions and interpretation Sampling - Hair Hair Collection for subsequent drug of abuse analysis - Saliva Saliva Collection for subsequent drug of abuse analysis Method Method based on European Laboratory Guidelines for Legally Defensible Workplace Drug Testing, Version 1, 2002, using the Quantisal Device B B -Urine Specimen collection for subsequent drug of abuse analysis Method based on European Laboratory Guidelines for Legally Defensible Workplace Drug Testing, Version 1, 2002 B END ssessment Manager: HM Page 11 of 11

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