IJC International Journal of Cancer
|
|
- Neil Barton
- 5 years ago
- Views:
Transcription
1 IJC International Journal of Cancer Association between height and thyroid cancer risk: A meta-analysis of prospective studies Zhaohai Jing 1 *, Xu Hou 1 *, Ying Liu 1, Shengli Yan 1, Robin Wang 1,2, Shihua Zhao 1 and Yangang Wang 1 1 Department of Endocrinology, Affiliated Hospital of Qingdao University, Qingdao, , China 2 Department of Medicine, Second Military Medical University, Shanghai , China While several epidemiological studies have investigated the relationship between height and risk for thyroid cancer, the results were inconsistent. In the present study, a systematic review and meta-analysis of prospective studies was conducted to assess the impact of height on thyroid cancer risk. Online databases were searched up to December 30, 2014, for prospective studies on the association between height and thyroid cancer risk. Pooled relative risks (RRs) and 5% confidence intervals (CIs) were calculated using a random-effects model of meta-analysis. In all, 11 articles were included in this meta-analysis, including 15 prospective studies, containing 6,65,53 participants and 7,062 cases of thyroid cancer. By comparing the highest versus the lowest categories of height, we reported that risk of thyroid cancer was increased with height in both men (summary RR , 5%CI , p ) and women (summary RR , 5%CI , p < 0.001). The summary RR of thyroid cancer per 5-cm increase in height was 1.16 (5%CI , p < 0.001). The results were similar among men (per 5-cm increase RR , 5%CI , p ) and women (per 5-cm increase RR 5 1.1, 5%CI , p < 0.001). No obvious risk of publication bias was observed. Our meta-analysis provides strong evidence for a dose response relationship between height and risk of thyroid cancer in both men and women. Thyroid cancer is the most common malignant tumor of the endocrine system, accounting for about 1% of all cancers. 1 The incidence of thyroid cancer is.1 per 100,000 worldwide. 2 The incidence of thyroid cancer has been rising over the recent years, which may be primarily due to more sensitive diagnostic techniques and increased number of cases induced by enhanced environmental exposure. 3 It has been known that multiple factors are involved in thyroid carcinogenesis, such as genetic and environmental factors. 4,5 Identification of risk Key words: thyroid cancer, height, meta-analysis Abbreviations: CI: confidence interval; IGF-1: insulin-like growth factor-1; NOS: Newcastle Ottawa scale; RR: relative risk Z.J., B.W., Y.W. and S.Z. conceived the study aims and design, contributed to the systematic review, interpreted the results and drafted the article. Z.J., Y.L., X.H. and S.Y. performed data extraction, completed the analyses and revised the article. All authors discussed the results and reviewed and edited the article *Z.J. and X.H. contributed equally to this study DOI: /ijc.247 History: Received 2 Dec 2014; Accepted 12 Feb 2015; Online 1 Feb 2015 Correspondence to: Shihua Zhao, Department of Endocrinology, Affiliated Hospital of Qingdao University, Qingdao , China, Tel: , Fax: , zhaosh@ qdumh.qd.sd.cn or Yangang Wang, Department of Endocrinology, Affiliated Hospital of Qingdao University, Qingdao , China, Tel: , Fax: , wangyg166@126.com factors for thyroid cancer can help us get a better understanding of the pathogenesis of thyroid carcinogenesis and develop more effective preventive interventions for high-risk population. Currently, the well-known risk factor for thyroid cancer is exposure to ionizing radiation. 4 Other possible risk factors for thyroid cancer such as obesity and diabetes have also been identified. 6 Previous epidemiological studies have suggested that taller people have an increased risk for cancer, such as prostate cancer, pancreatic cancer, ovarian cancer and breast cancer, and thus height has been proposed as a risk factor of cancer in the past decade. 11 There were also a number of studies assessing the relationship between height and risk for thyroid cancer, but the results were inconsistent. 7,14 21 Hereby we have performed a systematic review and metaanalysis of prospective studies to get a more precise assessment of the impact of height on thyroid cancer risk. Material and Methods Literature search and study selection PubMed, Web of Science and Embase were searched for prospective studies assessing the association between height and risk of thyroid cancer. In the literature search, there was no language limitation and no regional limitation. The following search terms were employed to retrieve the relevant literatures in the databases listed previously: ( height or body size ) and ( thyroid cancer, thyroid carcinoma or thyroid tumor ) and ( prospective, or longitudinal ). The search time was up to December 30, The references of included studies and relevant reviews were also checked for eligible studies.
2 Jing et al. 145 What s new? The taller a person is, the greater his or her risk for thyroid cancer may be, although not all studies on the subject have reached that same conclusion. To gain a clearer picture of the relationship between height and thyroid cancer, the present meta-analysis took into consideration data from 15 prospective studies. The findings of the analysis corroborate the existence of an association, whereby thyroid cancer risk increases with increasing height, in both men and women. Although the mechanistic basis for the association awaits elucidation, pathways centering on insulin-like growth factor-1 (IGF-1), which influences growth, are implicated. To be included in the meta-analysis, the studies must meet the following criteria: (i) prospective studies; (ii) assessing the relationship between height and risk of thyroid cancer and (iii) reporting relative risks (RRs) and 5% confidence intervals (5%CIs) for thyroid cancer risk. Retrospective, cross-section and case-control studies were all excluded. Studies with overlapping data were also excluded. Data extraction and quality assessment Two investigators performed the data extraction independently. If there was any disagreement between the two investigators, it was resolved by discussion until consensus was reached between the investigators. The following data were extracted from each included study: publication year, first author s name, study design, country, number of participants, number of cases, time of follow-up, gender distribution, types of thyroid cancer, confounding factors and RRs with corresponding 5%CIs. For studies providing RRs with different adjusted factors, the most adjusted RRs were used in the meta-analysis. The quality of prospective studies was assessed using the Newcastle Ottawa scale (NOS), 22 generating a maximum of nine stars to each study, including four stars for the selection of participants, two stars for the comparability of participants and three stars for the assessment of outcomes. Quality was assigned according to the scores so that 7 stars indicated high quality, 4 6 stars for middle quality and 0 3 stars for low quality. The scores were determined by two investigators and if there was any disagreement between the two investigators, it was resolved by discussion until consensus was reached. Data analysis We first determined the summary RRs of thyroid cancer comparing the highest versus the lowest categories, and then calculated the summary RRs of thyroid cancer per 5-cm increase in height. Statistical heterogeneity between studies was evaluated with the I 2 statistic method where I 2 [mt]50% indicated obvious heterogeneity. Since there was obvious difference in the categories of height and other baseline characteristics, we calculated the pooled RRs and 5%CIs using the random-effects model of meta-analysis. Subgroup analysis was performed by gender (men or women), thyroid cancer histology (differentiated thyroid cancer or all types of thyroid cancer) and age (adults or nonadults). Sensitivity analysis was performed by omitting one single study by turns to test the variability of the pooled RRs. Publication bias was assessed by visual inspection of the funnel plot. Asymmetry of the funnel plot was further assessed using Egger s regression test. All statistical analyses were performed using STATA version A two-tailed p < 0.05 was considered statistically significant. Results Study characteristics Of the 223 individual studies identified from our literature search, 205 were excluded initially after reviewing titles and abstracts, and 1 studies were thoroughly assessed by full-text reading, which further excluded another seven studies. Finally, 11 studies 7,14 21 were included into this metaanalysis, including 15 prospective studies. 7,14 21 The selected studies involved a total of 6,65,53 participants and 7,062 cases of thyroid cancer (Table 1). The main characteristics of the selected studies were shown in Table 1. Within the selected studies, there were four studies from United States,,14,17,1 one study from Norway, 7 one study from Korea, 15 one study from France, 16 one study from Canada, 1 one study from Denmark, 21 one study from Israel 20 and one study from ten European countries. The time of follow-up in these studies ranged from.7 to 3.6 years (Table 1). According to the quality criteria, all of the 11 studies were of the high-quality category (Table 1). Seven studies investigated the relationship between height and thyroid cancer in women, 7,,15 1,20 five studies investigated that in men 7,,15,17,20 and one study in mixed population. 14 Among the 11 studies, focused on all types of thyroid cancer, 7,,14,15,17 21, and 2 on differentiated thyroid cancer (DTC).,16 Eight studies reported the RRs of thyroid cancer comparing the highest versus the lowest categories of height, 7,,14 1,20 whereas seven studies reported RRs of thyroid cancer per 5-cm increase in height. 7,15,1,1,21 Height and risk of thyroid cancer Obvious heterogeneity was present among the eight studies 7,,14 1,20 reporting RRs comparing the highest versus the lowest categories of height (I %). Meta-analysis of these studies 7,,14 1,20 showed that larger height was associated with increased risk of thyroid cancer (summary RR 5 1.4, 5%CI
3 146 Height and thyroid cancer Table 1. The main characteristics of those 11 prospective studies included into the meta-analysis Study Country Design Participants Cases Iribarren United et al. 14 States 204,64 persons (aged 10 at baseline, 54% females) Follow-up (year) Height range Adjusted factors Quality All heights Age, gender, race, education, smoking, self-reported personal history, family history of thyroid disease, BMI, weight gain and occupational exposures. Engeland Norway et al. 7 2,001,727 persons (aged years, 51.% females) 3, All heights Age at measurement, year of birth and BMI. Sung Korea et al. 15 7,7 persons (40 64 years of age at baseline, 4.1% females) 43.7 Men ( cm); women ( cm) Age, body mass index, cigarette smoking, alcohol consumption and regular exercise, monthly salary, occupation and area of residence. Meinhold United et al. 17 States 0,713 radiologic technologists (76.6% females) All heights Birth year, smoking status, body mass index, number of personal radiographs to the head or neck, cumulative occupational radiation dose and medical history of benign thyroid conditions. Clavel- Chapelon et al. 16 France 1,0 women with the age of years at inclusion in All heights Age, and stratified on year of birth, history of goiter or thyroid nodules, smoking status, iodine. Kitahara United et al. States Five prospective 413,7 women and 434,53 men with mean age at a baseline of 5.2 years 1, All heights Education, race, marital status, smoking, alcohol intake and (where appropriate) and sex Kabat United et al. 1 States 144,31 postmenopausal women (aged 50 and 7) All heights Age, age at first full-term pregnancy, education, pack-years of smoking, alcohol intake, MET-hours/week, history of benign thyroid disease, OS/CT and randomization status in CT Rinaldi Ten et al. European countries 343,765 female and 146,24 male (aged 35 6 years, 70.1%females) 566 Appr. 10 All heights Center and age at recruitment, age and smoking.
4 Jing et al. 147 Table 1. The main characteristics of those 11 prospective studies included into the meta-analysis (Continued) Follow-up (year) Height range Adjusted factors Quality Study Country Design Participants Cases All heights Age at entry, menopausal status and years of education, BMI.,256 women (aged 40 5 years) Kabat Canada et al. 1 Age as the time metric, BMI, birth weight Women ( cm); men ( cm) 321,05 children (aged 7 to 13 years) Kitahara Denmark et al All heights Year of birth, country of origin and years of schooling are for the model with height introduced in cm. 1,624,310 participants (aged 16 1 years) Farfel Israel et al , p < 0.001; Fig. 1). Subgroup analysis by gender showed that, by comparing the highest versus the lowest categories of height, the risk of thyroid cancer was increased in both men 7,,15,17,20 (summary RR , 5%CI , p ) and women 7,,15 1,20 (summary RR , 5%CI , p < 0.001). Subgroup analysis by thyroid cancer pathology classification showed that, by comparing the highest versus the lowest categories of height, the risk of thyroid cancer was increased in both DTC,16 (summary RR , 5%CI , p ) and all types of thyroid cancer 7,,14,15,17 21 (summary RR 5 1.4, 5%CI , p <0.001). Subgroup analysis by age showed that, by comparing the highest versus the lowest categories of height, the risk of thyroid cancer was increased in both adults 7,,14 1 (summary RR , 5%CI , p < 0.001) and nonadults 20 (summary RR , 5%CI , p < 0.001). Obvious heterogeneity was observed among the seven studies 7,15,1,1,21 reporting RRs of thyroid cancer per 5-cm increase in height (I %). Meta-analysis of these studies showed that the summary RR of thyroid cancer per 5-cm increase in height was 1.16 (5%CI , p < 0.001; Fig. 2). The results were similar in men 7,15,21 (per 5-cm increase RR , 5%CI , p ) and women 7,15,1,1,21 (per 5-cm increase RR 5 1.1, 5%CI , p < 0.001; Fig. 2). Publication bias Visual inspection of the funnel plot did not detect obvious asymmetry. The Egger s regression asymmetry test showed no evidence of publication bias for the association between height and thyroid cancer risk (p 5 0.7). Thus, no obvious risk of publication bias was observed in the meta-analysis. Discussion Although some epidemiological studies have investigated the relationship between height and the risk of thyroid cancer, the results were far from consistent. In the studies included in the present meta-analysis, five reported the absence of statistically significant association between height and risk of thyroid cancer (Figs. 1 and 2). The present systematic review and meta-analysis of published observational study evaluated the influence of height on risk of thyroid cancer in 11 studies, including 6,65,53 participants and 7,062 cases of thyroid cancer. While previous studies have suggested that height might be a risk factor for carcinogenesis, the present meta-analysis and subgroup analysis by gender indicate the presence of a strong association between height and risk of thyroid cancer in both men and women. Our meta-analysis also suggested a dose response relationship between height and risk of thyroid cancer in both men and women. The summary RR of thyroid cancer per 5-cm increase in height was The results were similar in men (per 5-cm increase RR ) and women (per 5-cm increase RR < 0.001). The dose response relationship above
5 14 Height and thyroid cancer Figure 1. Forest plot showing the relationship between height and risk of thyroid cancer by comparing the highest versus the lowest categories of height. [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com.] further strengthened the association between height and risk of thyroid cancer. A number of studies have reported correlation between height and different types of cancer. Jane Green s 11 study containing 1,27,124 participants from UK showed that the summary RR was 1.14 (5%CI ) per 10 cm increase in height in all cancers, and that height was associated with an increased risk for breast cancer with a summary RR at 1.17 (5%CI ). Zuccolo s 12 study containing 30 and 27 case-control studies from nine UK cities reported that height was positively associated with prostate cancer (random-effects RR per 10 cm: 1.06; 5%CI ). Leo J. Schouten s 13 study containing twelve prospective studies from North America and Europe showed that height was associated with an increased ovarian cancer risk, and women with height 1.70 m had a pooled multivariate RR of 1.3 (5%CI ) compared to those with height <1.60 m. Aune s 10 study containing twelve studies (seven from Europe, four from North American and one from South Korea) showed that larger height was associated with increased risk for pancreatic cancer with a summary RR per 5-cm increase in height at 1.07 (5%CI ). The findings in our meta-analysis show an obvious association between height and risk of thyroid cancer in both men and women, which adds new evidence for the relationship between height and cancer risk. The biological mechanisms underlying the effects of height on thyroid carcinogenesis remain unknown at this stage. The insulin-like growth factor-1 (IGF-1) system might be a plausible mechanism for the association between height and thyroid cancer. The findings from Schmidt et al. s study 23 showed that IGF-1 concentration was associated with risk of thyroid carcinoma, in which a positive association between IGF-1 concentration and risk of differentiated thyroid carcinoma was reported, with an odds ratio for a doubling in IGF-1 concentration at 1.4 (5% confidence interval: ).[AQ4] The IGF-1 can influence height and plays an important role in the regulation of postnatal growth, and taller people have higher levels of IGF-1 in childhood and adolescence, which may result in increased risk of thyroid cancer. IGF-1 levels in adulthood can be influenced by food and energy intake in early childhood. 24 Higher IGF-1 levels promote mutation in various cell lines including thyroid cells. 20,24 On the other hand, the IGFs may contribute to cancer risk by stimulating cell proliferation, adhesion and migration, and inhibiting apoptosis. 20,24 Our meta-analysis also had some limitations. In this study, only two studies focused on the association between
6 Jing et al. 14 Figure 2. Forest plot showing the risk of thyroid cancer per 5-cm increase in height. [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com.] height and DTC, while the other nine studies focused on all types of thyroid cancer without differentiating thyroid cancer histology. We performed a subgroup analysis by thyroid cancer pathology classification and found that risk of thyroid cancer was increased in both DTC and all types of thyroid cancer. Future studies are needed to further assess the relationship between height and different types of thyroid cancer by histology. In addition, none of the selected studies examined the effects of height on prognosis of thyroid cancer. As a result, we were unable to explore the relationship between height and prognosis of thyroid cancer. Finally, this metaanalysis had regional restrictions, as most of the included studies were from the western countries. More prospective studies with well-design from Asian and African countries would be helpful to examine the validity our findings in a broader scope. In conclusion, the results from this meta-analysis strongly support that larger height is associated with an increased risk of thyroid cancer in both men and women. Acknowledgements We thank the authors for providing the data included the study. References 1. Schneider DF, Chen H. New developments in the diagnosis and treatment of thyroid cancer. CA Cancer J Clin 2013;63: Jemal A, Bray F, Center MM, et al. Global cancer statistics. CA Cancer J Clin 2011;61: Vigneri R, Malandrino P, Vigneri P. The changing epidemiology of thyroid cancer: why is incidence increasing? Curr Opin Oncol 2015;27: Landa I, Robledo M. Association studies in thyroid cancer susceptibility: are we on the right track? J Mol Endocrinol 2011;47:R Adjadj E, Schlumberger M, de Vathaire F. Germline DNA polymorphisms and susceptibility to differentiated thyroid cancer. Lancet Oncol 200; 10: Yeo Y, Ma SH, Hwang Y, et al. Diabetes mellitus and risk of thyroid cancer: a meta-analysis. PLoS One 2014;:e Engeland A, Tretli S, Akslen LA, et al. Body size and thyroid cancer in two million Norwegian men and women. Br J Cancer 2006;5: Kitahara CM, Platz EA, Freeman LE, et al. Obesity and thyroid cancer risk among U.S. men and women: a pooled analysis of five prospective studies. Cancer Epidemiol Biomarkers Prev 2011; 20: Rinaldi S, Lise M, Clavel-Chapelon F, et al. Body size and risk of differentiated thyroid carcinomas: findings from the EPIC study. Int J Cancer 2012; 131:E Aune D, Vieira AR, Chan DS, et al. Height and pancreatic cancer risk: a systematic review and meta-analysis of studies. Cancer Causes Control 2012;23: Green J, Cairns BJ, Casabonne D, et al. Height and cancer incidence in the million women study: prospective, and meta-analysis of prospective studies of height and total cancer risk. Lancet Oncol 2011;12: Zuccolo L, Harris R, Gunnell D, et al. Height and prostate cancer risk: a large nested case-control study (ProtecT) and meta-analysis. Cancer. Epidemiol Biomarkers Prev 200;17: Schouten LJ, Rivera C, Hunter DJ, et al. Height, body mass index, and ovarian cancer: a pooled analysis of 12 studies. Cancer. Epidemiol Biomarkers Prev 200;17:02 12.
7 140 Height and thyroid cancer 14. Iribarren C, Haselkorn T, Tekawa IS, et al. Cohort study of thyroid cancer in a San Francisco bay area population. Int J Cancer 2001;3: Sung J, Song YM, Lawlor DA, et al. Height and site-specific cancer risk: a study of a Korean adult population. Am J Epidemiol 200; 170: Clavel-Chapelon F, Guillas G, Tondeur L, et al. Risk of differentiated thyroid cancer in relation to adult weight, height and body shape over life: the French E3N. Int J Cancer 2010; 126: Meinhold CL, Ron E, Schonfeld SJ, et al. Nonradiation risk factors for thyroid cancer in the US radiologic technologists study. Am J Epidemiol 2010;171: Kabat GC, Kim MY, Thomson CA, et al. Anthropometric factors and physical activity and risk of thyroid cancer in postmenopausal women. Cancer Causes Control 2012;23: Kabat GC, Heo M, Kamensky V, et al. Adult height in relation to risk of cancer in a of Canadian women. Int J Cancer 2013;132: Farfel A, Kark JD, Derazne E, et al. Predictors for thyroid carcinoma in Israel: a national of 1,624,310 adolescents followed for up to 40 years. Thyroid 2014;24: Kitahara CM, Gamborg M, Berrington de Gonzalez A, et al. Childhood height and body mass index were associated with risk of adult thyroid cancer in a large study. Cancer Res 2014;74: Wells GA, Shea B, O connell D, et al. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomized studies in meta-analyses. Ottawa, Canada: Ottawa Health Research Institute, Schmidt JA, Allen NE, Almquist M, et al. Insulin-like growth factor-i and risk of differentiated thyroid carcinoma in the European prospective investigation into cancer and nutrition. Cancer Epidemiol Biomarkers Prev 2014;23: Ben-Shlomo Y, Holly J, McCarthy A, et al. Prenatal and postnatal milk supplementation and adult insulin-like growth factor I: long-term follow-up of a randomized controlled trial. Cancer Epidemiol Biomarkers Prev 2005; 14:1336.
Lack of association between IL-6-174G>C polymorphism and lung cancer: a metaanalysis
Lack of association between IL-6-174G>C polymorphism and lung cancer: a metaanalysis Y. Liu, X.L. Song, G.L. Zhang, A.M. Peng, P.F. Fu, P. Li, M. Tan, X. Li, M. Li and C.H. Wang Department of Respiratory
More informationBody size and thyroid nodules in healthy Korean population
J Korean Surg Soc 2012;82:13-17 http://dx.doi.org/10.4174/jkss.2012.82.1.13 ORIGINAL ARTICLE JKSS Journal of the Korean Surgical Society pissn 2233-7903 ㆍ eissn 2093-0488 Body size and thyroid nodules
More informationZhengtao Liu 1,2,3*, Shuping Que 4*, Lin Zhou 1,2,3 Author affiliation:
Dose-response Relationship of Serum Uric Acid with Metabolic Syndrome and Non-alcoholic Fatty Liver Disease Incidence: AMeta-analysis of Prospective Studies Zhengtao Liu 1,2,3*, Shuping Que 4*, Lin Zhou
More informationAssociation between the -77T>C polymorphism in the DNA repair gene XRCC1 and lung cancer risk
Association between the -77T>C polymorphism in the DNA repair gene XRCC1 and lung cancer risk B.B. Sun, J.Z. Wu, Y.G. Li and L.J. Ma Department of Respiratory Medicine, People s Hospital Affiliated to
More informationRESEARCH. Dagfinn Aune, 1,2 Abhijit Sen, 1 Manya Prasad, 3 Teresa Norat, 2 Imre Janszky, 1 Serena Tonstad, 3 Pål Romundstad, 1 Lars J Vatten 1
open access BMI and all cause mortality: systematic review and non-linear dose-response meta-analysis of 230 cohort studies with 3.74 million deaths among 30.3 million participants Dagfinn Aune, 1,2 Abhijit
More informationTotal Calcium (Dietary and Supplementary) Intake and Prostate Cancer: a Systematic Review and Meta-Analysis
DOI:10.22034/APJCP.2018.19.6.1449 Total Calcium (Diet and Supplements) and Prostate Cancer REVIEW Editorial Process: Submission:09/26/2017 Acceptance:05/16/2018 Total Calcium (Dietary and Supplementary)
More informationThe Expression of Beclin-1 in Hepatocellular Carcinoma and Non-Tumor Liver Tissue: A Meta-Analysis
The Expression of Beclin-1 in Hepatocellular Carcinoma and Non-Tumor Liver Tissue: A Meta-Analysis Zhiqiang Qin¹, Xinjuan Yu², Jinkun Wu¹, Mei Lin¹ 1 Department of Pathology, School of Basic Medicine,
More informationHeight and body fatness and colorectal cancer risk: an update of the WCRF AICR systematic review of published prospective studies
DOI 10.1007/s00394-017-1557-1 REVIEW Height and body fatness and colorectal cancer risk: an update of the WCRF AICR systematic review of published prospective studies Leila Abar 1 Ana Rita Vieira 1 Dagfinn
More informationAssociation between the CYP11B2 gene 344T>C polymorphism and coronary artery disease: a meta-analysis
Association between the CYP11B2 gene 344T>C polymorphism and coronary artery disease: a meta-analysis Y. Liu, H.L. Liu, W. Han, S.J. Yu and J. Zhang Department of Cardiology, The General Hospital of the
More informationBody Iron Stores and Heme-Iron Intake in Relation to Risk of Type 2 Diabetes: A Systematic Review and Meta- Analysis
Body Iron Stores and Heme-Iron Intake in Relation to Risk of Type 2 Diabetes: A Systematic Review and Meta- Analysis Zhuoxian Zhao 1, Sheyu Li 1, Guanjian Liu 2, Fangfang Yan 1, Xuelei Ma 3, Zeyu Huang
More informationAppendix 1: Systematic Review Protocol [posted as supplied by author]
Appendix 1: Systematic Review Protocol [posted as supplied by author] Title Physical Activity and Risks of Breast Cancer, Colon Cancer,, Ischemic Heart Disease and Ischemic Stroke Events: A Systematic
More informationReliability of Echocardiography Measurement of Patent Ductus Arteriosus Minimum Diameter: A Meta-analysis
International Journal of Cardiovascular and Cerebrovascular Disease 4(): 15-19, 016 DOI: 10.13189/ijccd.016.04001 http://www.hrpub.org Reliability of Echocardiography Measurement of Patent Ductus Arteriosus
More informationResearching Genetic Influences in Different Racial/Ethnic Populations and Cancer
Researching Genetic Influences in Different Racial/Ethnic Populations and Cancer Lenora WM Loo, PhD Assistant Professor (Specialist) University of Hawaii Cancer Center Off-Label Use Disclosure I do not
More informationThe WCRF/AICR Third Expert Report Diet, Nutrition, Physical Activity and Cancer: a Global Perspective Methods, Approaches and Lessons Learned
The WCRF/AICR Third Expert Report Diet, Nutrition, Physical Activity and Cancer: a Global Perspective Methods, Approaches and Lessons Learned Teresa Norat, PhD Principal Research Fellow Imperial College
More informationChapter 2 The Link Between Obesity and Breast Cancer Risk: Epidemiological Evidence
Chapter 2 The Link Between Obesity and Breast Cancer Risk: Epidemiological Evidence 2.1 BMI and Breast Cancer Risk BMI is routinely used to qualify an individual s adiposity, yet it is simply a measure
More information2. Studies of Cancer in Humans
346 IARC MONOGRAPHS VOLUME 72 2. Studies of Cancer in Humans 2.1 Breast cancer 2.1.1 Results of published studies Eight studies have been published on the relationship between the incidence of breast cancer
More informationFTO Polymorphisms Are Associated with Obesity But Not with Diabetes in East Asian Populations: A Meta analysis
BIOMEDICAL AND ENVIRONMENTAL SCIENCES 22, 449 457 (2009) www.besjournal.com FTO Polymorphisms Are Associated with Obesity But Not with Diabetes in East Asian Populations: A Meta analysis BO XI #, + AND
More informationDRAFT. No. of cases/ deaths. categories. Number of X-ray exposures (for UK & Ireland only ever vs never)
Table 2.1. Cohort studies of X-ray and Andrieu et al. (2006) Europe & Canada Carr et al. (2002) US cohort X- rays for treatment of peptic ulcers 1601 female BRCA1 + BRCA2 carriers, aged 18+; disease ascertainment
More information8/10/2012. Education level and diabetes risk: The EPIC-InterAct study AIM. Background. Case-cohort design. Int J Epidemiol 2012 (in press)
Education level and diabetes risk: The EPIC-InterAct study 50 authors from European countries Int J Epidemiol 2012 (in press) Background Type 2 diabetes mellitus (T2DM) is one of the most common chronic
More informationAssociation between the interleukin-1β gene -511C/T polymorphism and ischemic stroke: an updated meta-analysis
Association between the interleukin-1β gene -511C/T polymorphism and ischemic stroke: an updated meta-analysis W. Yan, Z.Y. Chen, J.Q. Chen and H.M. Chen Department of Neurology, Ningbo No. 2 Hospital,
More informationReview Article Long Noncoding RNA H19 in Digestive System Cancers: A Meta-Analysis of Its Association with Pathological Features
BioMed Research International Volume 2016, Article ID 4863609, 8 pages http://dx.doi.org/10.1155/2016/4863609 Review Article Long Noncoding RNA H19 in Digestive System Cancers: A Meta-Analysis of Its Association
More informationCancer Survivors: - Asian Perspective
Cancer Survivors: What we Know, What we Need to Know - Asian Perspective Prof. Josette Sin-yee Chor School of Public Health and Primary Care The Chinese University of Hong Kong Asia Varying incidence of
More informationSurveillance report Published: 9 January 2017 nice.org.uk
Surveillance report 2017 Caesarean section (2011) NICE guideline CG132 Surveillance report Published: 9 January 2017 nice.org.uk NICE 2017. All rights reserved. Contents Surveillance decision... 3 Reason
More informationRESEARCH ARTICLE. Common Variants in the PALB2 Gene Confer Susceptibility to Breast Cancer: a Meta-analysis
DOI:http://dx.doi.org/10.7314/APJCP.2013.14.12.7149 Common Variants in the PALB2 Gene Confer Susceptibility to Breast Cancer: a Meta-analysis RESEARCH ARTICLE Common Variants in the PALB2 Gene Confer Susceptibility
More informationRelation of Height and Body Mass Index to Renal Cell Carcinoma in Two Million Norwegian Men and Women
American Journal of Epidemiology Copyright 2004 by the Johns Hopkins Bloomberg School of Public Health All rights reserved Vol. 160, No. 12 Printed in U.S.A. DOI: 10.1093/aje/kwh345 Relation of Height
More informationAssociation of mir-21 with esophageal cancer prognosis: a meta-analysis
Association of mir-21 with esophageal cancer prognosis: a meta-analysis S.-W. Wen 1, Y.-F. Zhang 1, Y. Li 1, Z.-X. Liu 2, H.-L. Lv 1, Z.-H. Li 1, Y.-Z. Xu 1, Y.-G. Zhu 1 and Z.-Q. Tian 1 1 Department of
More informationAssociation between alcohol consumption and the risk of ovarian cancer: a meta-analysis of prospective observational studies
Yan-Hong et al. BMC Public Health (2015) 15:223 DOI 10.1186/s12889-015-1355-8 RESEARCH ARTICLE Open Access Association between alcohol consumption and the risk of ovarian cancer: a meta-analysis of prospective
More informationThe incidence of breast cancer among female flight attendants: an updated meta-analysis
Journal of Travel Medicine, 2016, 1 7 doi: 10.1093/jtm/taw055 Review Review The incidence of breast cancer among female flight attendants: an updated meta-analysis Tiebing Liu 1,, *, Chanyuan Zhang 2,,
More informationS e c t i o n 4 S e c t i o n4
Section 4 Diet and breast cancer has been investigated extensively, although the overall evidence surrounding the potential relation between dietary factors and breast cancer carcinogenesis has resulted
More informationThe objective of this systematic review is to assess the impact of migration on the risk of developing gastric cancer.
Review title The effect of migration on gastric cancer risk: A systematic review protocol Reviewers Haejin In, MD, MBA, MPH 1 Marisa Langdon-Embry, MS 2 1 Albert Einstein College of Medicine, haejin.in@einstein.yu.edu
More informationDiabetes Mellitus and Breast Cancer
Masur K, Thévenod F, Zänker KS (eds): Diabetes and Cancer. Epidemiological Evidence and Molecular Links. Front Diabetes. Basel, Karger, 2008, vol 19, pp 97 113 Diabetes Mellitus and Breast Cancer Ido Wolf
More informationIncreased risk of cancer with anti-diabetes drugs? : pros
24 th Spring Congress of Korean Diabetes Association Increased risk of cancer with anti-diabetes drugs? : pros Nan Hee Kim, MD, Ph.D. Professor Korea University Medical School Contents Diabetes and cancer
More informationCorrelations between the COMT gene rs4680 polymorphism and susceptibility to ovarian cancer
Correlations between the COMT gene rs4680 polymorphism and susceptibility to ovarian cancer W. Pan 1 and H. Liao 2 1 Department of Obstetrics and Gynecology, Huangshi Central Hospital of Hubei Province
More informationDietary soy intake and changes of mammographic density in premenopausal Chinese women
Dietary soy intake and changes of mammographic density in premenopausal Chinese women 2010 WCRF International Conference, Nutrition, Physical Activity and Cancer Prevention: Current Challenges, New Horizons
More informationA systemic review and meta-analysis for prognostic values of pretreatment lymphocyte-to-monocyte ratio on gastric cancer
831094EJI0010.1177/2058739219831094European Journal of InflammationLi et al. letter2019 Letter to the Editor A systemic review and meta-analysis for prognostic values of pretreatment lymphocyte-to-monocyte
More informationCancer Risk Factors in Ontario. Other Radiation
Cancer Risk Factors in Ontario Other Radiation OTHer radiation risk factor/ exposure Radon-222 and decay products X-radiation, gamma radiation Cancer The context where high risks were reported Magnitude
More informationOverview of Epidemiological Studies and Trends in Paediatric CT use. Mark S. Pearce, PhD
Overview of Epidemiological Studies and Trends in Paediatric CT use Mark S. Pearce, PhD CT scan usage A very useful tool Introduced in 1973 for head scanning Available worldwide at over 30,000 centres
More informationAmerican Journal of Internal Medicine
American Journal of Internal Medicine 2016; 4(3): 49-59 http://www.sciencepublishinggroup.com/j/ajim doi: 10.11648/j.ajim.20160403.12 ISSN: 2330-4316 (Print); ISSN: 2330-4324 (Online) The Effect of Dose-Reduced
More informationRisk Factors for Breast Cancer
Lifestyle Factors The variations seen both regionally and internationally in breast cancer incidence have heightened interest in the medical community in the role of lifestyle-related influences. In general,
More informationAssociations between the SRD5A2 gene V89L and TA repeat polymorphisms and breast cancer risk: a meta-analysis
Associations between the SRD5A2 gene V89L and TA repeat polymorphisms and breast cancer risk: a meta-analysis D. Zhang 1, Q. Li 2, H.-C. Qu 3, T. Yu 2 and Y.-R. Liu 1 1 College of Basic Medical Science,
More informationDIABETES, PHYSICAL ACTIVITY AND ENDOMETRIAL CANCER. Emilie Friberg
Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, 2006 DIABETES, PHYSICAL ACTIVITY AND ENDOMETRIAL CANCER Emilie Friberg Stockholm 2006
More informationDiet, obesity, lifestyle and cancer prevention:
Diet, obesity, lifestyle and cancer prevention: Epidemiologic perspectives Graham A Colditz, MD DrPH Niess-Gain Professor Chief, November, 2017 Outline Review evidence on contribution of diet, obesity,
More informationContinuous update of the WCRF-AICR report on diet and cancer. Protocol: Breast Cancer. Prepared by: Imperial College Team
Continuous update of the WCRF-AICR report on diet and cancer Protocol: Breast Cancer Prepared by: Imperial College Team The current protocol for the continuous update should ensure consistency of approach
More informationThe association between dietary protein intake and colorectal cancer risk: a metaanalysis
Lai et al. World Journal of Surgical Oncology (2017) 15:169 DOI 10.1186/s12957-017-1241-1 RESEARCH Open Access The association between dietary protein intake and colorectal cancer risk: a metaanalysis
More informationPooled analysis of association between a genetic variant in the 3'-untranslated region of Toll-like receptor 4 and cancer risk
Pooled analysis of association between a genetic variant in the 3'-untranslated region of Toll-like receptor 4 and cancer risk X. Wang*, Z. Xu* and C.H. Miao Department of Anesthesiology, Shanghai Cancer
More informationSystematic reviews and meta-analyses of observational studies (MOOSE): Checklist.
Systematic reviews and meta-analyses of observational studies (MOOSE): Checklist. MOOSE Checklist Infliximab reduces hospitalizations and surgery interventions in patients with inflammatory bowel disease:
More informationOnline Supplementary Material
Section 1. Adapted Newcastle-Ottawa Scale The adaptation consisted of allowing case-control studies to earn a star when the case definition is based on record linkage, to liken the evaluation of case-control
More informationAssociation between the CYP1A1 polymorphisms and hepatocellular carcinoma: a meta-analysis
Association between the CYP1A1 polymorphisms and hepatocellular carcinoma: a meta-analysis B.W. Yu 1 *, L.Q. Zhang 1 *, X.L. Teng 1, Y. Zhang 1, L.B. Zou 2 and H.Y. Ying 3 l Department of Clinical Laboratory,
More informationMILK. Nutritious by nature. The science behind the health and nutritional impact of milk and dairy foods
MILK Nutritious by nature The science behind the health and nutritional impact of milk and dairy foods Cancer Based on a comprehensive review of the scientific literature, the World Cancer Research Fund
More informationTelevision Viewing and Time Spent Sedentary in Relation to Cancer Risk: A Meta-Analysis
DOI:10.1093/jnci/dju098 First published online June 1, 2014 The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com. REVIEW
More informationContinuous Update Project Keeping the science current d n u h F c r a e s e r R e c d C l r o Breast Cancer 2010 Report
World Cancer Research Fund American Institute for Cancer Research Continuous Update Project Keeping the science current Join a sponsored walk in your community to raise funds for World Cancer Research
More informationReview Article Prognostic Role of MicroRNA-200c-141 Cluster in Various Human Solid Malignant Neoplasms
Disease Markers Volume 2015, Article ID 935626, 19 pages http://dx.doi.org/10.1155/2015/935626 Review Article Prognostic Role of MicroRNA-200c-141 Cluster in Various Human Solid Malignant Neoplasms Xiao-yang
More informationThe association between dietary zinc intake and risk of pancreatic cancer: a meta-analysis
Research Article The association between dietary zinc intake and risk of pancreatic cancer: a meta-analysis Li Li and Xuesong Gai Department of Emergency Trauma Surgery, The First People s Hospital of
More informationWeight Change and Risk of Colorectal Cancer: A Systematic Review and Meta-Analysis
American Journal of Epidemiology The Author 2015. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail:
More informationThe association between methylenetetrahydrofolate reductase gene C677T polymorphisms and breast cancer risk in Chinese population
Tumor Biol. (2015) 36:9153 9158 DOI 10.1007/s13277-015-3321-6 EDITORIAL The association between methylenetetrahydrofolate reductase gene C677T polymorphisms and breast cancer risk in Chinese population
More informationIJC International Journal of Cancer
IJC International Journal of Cancer Association between adult weight gain and colorectal cancer: A dose response meta-analysis of observational studies Qi Chen 1, Jing Wang 1, Jinghui Yang 2, Zhichao Jin
More informationSupplement DS1 Search strategy. EMBASE Search Strategy
British Journal of Psychiatry doi: 10.1192/bjp.bp.111.106666 Vitamin D deficiency and depression in adults: systematic review and meta-analysis Rebecca E. S. Anglin, Zainab Samaan, Stephen D. Walter and
More informationAssociation between G-217A polymorphism in the AGT gene and essential hypertension: a meta-analysis
Association between G-217A polymorphism in the AGT gene and essential hypertension: a meta-analysis R. Yao*, Y.Y. Du*, Y.Z. Zhang, Q.H. Chen, L.S. Zhao and L. Li Department of Cardiology, the First Affiliated
More informationBMI and Breast Cancer in Korean Women: A Meta-Analysis
ORIGINAL ARTICLE BMI and Breast Cancer in Korean Women: A Meta-Analysis Dukyoo Jung 1, Sun-Mi Lee 2 * 1 Division of Nursing Science, College of Health Sciences, Ewha Womans University, Seoul, Korea 2 College
More information7.10 Breast FOOD, NUTRITION, PHYSICAL ACTIVITY, AND CANCER OF THE BREAST (POSTMENOPAUSE)
7.10 Breast FOOD, NUTRITION, PHYSICAL ACTIVITY, AND CANCER OF THE BREAST (PREMENOPAUSE) In the judgement of the Panel, the factors listed below modify the risk of cancer of the breast (premenopause). Judgements
More informationViral hepatitis and Hepatocellular Carcinoma
Viral hepatitis and Hepatocellular Carcinoma Hashem B. El-Serag, MD, MPH Dan L. Duncan Professor of Medicine Chief, Gastroenterology and Hepatology Houston VA & Baylor College of Medicine Houston, TX Outline
More informationCancer outcomes associated with food, food contaminants, obesity and dietary patterns: from science to policy
Cancer outcomes associated with food, food contaminants, obesity and dietary patterns: from science to policy Operationalising the WCRF/AICR cancer prevention recommendations using an index score: recent
More informationAssociation between the XPG gene Asp1104His polymorphism and lung cancer risk
Association between the XPG gene Asp1104His polymorphism and lung cancer risk B. Zhou, X.M. Hu and G.Y. Wu Department of Thoracic Surgery, Hunan Provincial Tumor Hospital, Changsha, China Corresponding
More informationSupplementary Text A. Full search strategy for each of the searched databases
Supplementary Text A. Full search strategy for each of the searched databases MEDLINE: ( diabetes mellitus, type 2 [MeSH Terms] OR type 2 diabetes mellitus [All Fields]) AND ( hypoglycemia [MeSH Terms]
More informationSupplementary Table 4. Study characteristics and association between OC use and endometrial cancer incidence
Supplementary Table 4. characteristics and association between OC use and endometrial cancer incidence a Details OR b 95% CI Covariates Region Case-control Parslov, 2000 (1) Danish women aged 25 49 yr
More informationCancer Cell Research 17 (2018)
Available at http:// www.cancercellresearch.org ISSN 2161-2609 Prognostic value of MicroRNA-21 in non-small cell lung cancer: a meta-analysis Fei Xu, Leina Ma, Lingxin Feng, Yinjie Wu, Xiaoyan Xu, Zhuang
More informationThe Diabetes Epidemic in Korea
Review Article Endocrinol Metab 2016;31:349-33 http://dx.doi.org/.3803/enm.2016.31.3.349 pissn 2093-96X eissn 2093-978 The Diabetes Epidemic in Korea Junghyun Noh Department of Internal Medicine, Inje
More informationThe angiotensin-converting enzyme (ACE) I/D polymorphism in Parkinson s disease
4432JRA0010.1177/1470320313494432Journal of the Renin-Angiotensin-Aldosterone SystemSu et al Original Article The angiotensin-converting enzyme (ACE) I/D polymorphism in Parkinson s disease Journal of
More information2018 Texas Cancer Registry Annual Report
2018 Texas Cancer Registry Annual Report As Required by Texas Health and Safety Code Section 82.007 November 2018 Table of Contents Executive Summary... 1 1. Introduction... 2 2. Background... 3 Cancer
More informationEffects of Bariatric Surgery on Incidence of Obesity-Related Cancers: A Meta-Analysis
e-issn 1643-3750 DOI: 10.12659/MSM.893553 Received: 2015.01.13 Accepted: 2015.02.23 Published: 2015.05. Effects of Bariatric Surgery on Incidence of Obesity-Related Cancers: A Meta-Analysis Authors Contribution:
More informationThe Role of Observational Studies. Edward Giovannucci, MD, ScD Departments of Nutrition and Epidemiology
The Role of Observational Studies Edward Giovannucci, MD, ScD Departments of Nutrition and Epidemiology Disclosure Information As required, I would like to report that I have no financial relationships
More informationMaterials and Methods
DOI:http://dx.doi.org/10.7314/APJCP.2014.15.18.7665 RESEARCH ARTICLE Body Mass Index Effects on Risk of Ovarian Cancer: A Meta- Analysis Jalal Poorolajal 1, Ensiyeh Jenabi 2 *, Seyyedeh Zahra Masoumi 3
More information(Seng, et al., 2013). Studies have reported prevalence rates ranging from 1 to 30 percent of
POSTPARTUM POSTTRAUMATIC STRESS DISORDER Introduction Recent research suggests that childbirth may be a significant cause of PTSD in women (Seng, et al., 2013). Studies have reported prevalence rates ranging
More informationwhat s new? CONFERENCE ALCOHOL AND HEALTH Amsterdam, 23 September 2010
CONFERENCE ALCOHOL AND HEALTH Amsterdam, 23 September 2010 Alcohol drinking and cancer risk: what s new? Dr Paule LATINO-MARTEL UMR U 557 Inserm, U 1125 Inra, Cnam, Université Paris 13; CRNH-IdF, France
More informationBenefits of Vitamin D for Cancer and Pregnancy/Birth Outcomes. William B. Grant, PhD Sunlight, Nutrition and Health Research Center, San Francisco
Benefits of Vitamin D for Cancer and Pregnancy/Birth Outcomes William B. Grant, PhD Sunlight, Nutrition and Health Research Center, San Francisco Disclosure I receive funding from Bio Tech Pharmacal, Inc.
More informationThe association between CDH1 promoter methylation and patients with ovarian cancer: a systematic meta-analysis
Wang et al. Journal of Ovarian Research (2016) 9:23 DOI 10.1186/s13048-016-0231-1 RESEARCH The association between CDH1 promoter methylation and patients with ovarian cancer: a systematic meta-analysis
More informationThe association between LEPR Q223R polymorphisms and breast cancer risk
Breast Cancer Res Treat (25) 5: 6 DOI.7/s549-5-3375-6 EDITORIAL The association between LEPR Q223R polymorphisms and breast cancer risk Yadong Wang Haiyan Yang 2 Huiyan Gao Haiyu Wang Received: 7 March
More informationThe Breast Cancer Family Registry: Description of Resource and some Applications
The Breast Cancer Family Registry: Description of Resource and some Applications Mary Beth Terry, PhD Associate Professor Department of Epidemiology Mailman School of Public Health Overview of Talk Description
More informationModifiers of Cancer Risk in BRCA1 and BRCA2 Mutation Carriers: A Systematic Review and Meta-Analysis
DOI:10.1093/jnci/dju091 First published online May 14, 2014 The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com. Review
More informationRelationship Between GSTT1 Gene Polymorphism and Hepatocellular Carcinoma in Patients from China
RESEARCH ARTICLE Relationship Between GSTT1 Gene Polymorphism and Hepatocellular Carcinoma in Patients from China Jie Chen, Liang Ma, Ning-Fu Peng, Shi-Jun Wang, Le-Qun Li* Abstract Objective: The results
More informationCruciferous vegetable consumption and the risk of pancreatic cancer: a meta-analysis
Li et al. World Journal of Surgical Oncology (2015) 13:44 DOI 10.1186/s12957-015-0454-4 WORLD JOURNAL OF SURGICAL ONCOLOGY RESEARCH Open Access Cruciferous vegetable consumption and the risk of pancreatic
More informationAssociation between ERCC1 and ERCC2 polymorphisms and breast cancer risk in a Chinese population
Association between ERCC1 and ERCC2 polymorphisms and breast cancer risk in a Chinese population R. Zhao and M.F. Ying Department of Pharmacy, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University,
More informationNutrition and gastrointestinal cancer: An update of the epidemiological evidence
Nutrition and gastrointestinal cancer: An update of the epidemiological evidence Krasimira Aleksandrova, PhD MPH Nutrition, Immunity and Metabolsim Start-up Lab Department of Epidemiology German Institute
More informationIJC International Journal of Cancer
IJC International Journal of Cancer Dietary total fat and fatty acids intake, serum fatty acids and risk of breast cancer: A meta-analysis of prospective cohort studies Yi Cao 1, Lin Hou 1 and Weijing
More informationPEER REVIEW HISTORY ARTICLE DETAILS VERSION 1 - REVIEW
PEER REVIEW HISTORY BMJ Open publishes all reviews undertaken for accepted manuscripts. Reviewers are asked to complete a checklist review form (see an example) and are provided with free text boxes to
More informationOriginal Article Association of tea consumption and the risk of thyroid cancer: a meta-analysis
Int J Clin Exp Med 2015;8(8):14345-14351 www.ijcem.com /ISSN:1940-5901/IJCEM0010987 Original Article Association of tea consumption and the risk of thyroid cancer: a meta-analysis Sugang Ma 1, Chunyan
More informationIncreased Risk of Cancer with Anti-diabetes Drugs? Cons
Increased Risk of Cancer with Anti-diabetes Drugs? Cons Inje University College of Medicine, Ilsanpaik Hospital, Department of Internal Medicine Dong-Jun Kim Gastroenterology132:2208-2225, 2007 IGF-1 System
More informationSupplementary Information
Supplementary Information Coffee consumption and bladder cancer: a meta-analysis of observational studies Weixiang Wu 1,2 ; Yeqing Tong 1,3 ; Qiang Zhao 2 ; Guangxia Yu 2 ; Xiaoyun Wei 2 ; Qing Lu 2,*
More informationOriginal Article Dietary nitrite and nitrate is not associated with adult glioma risk: a meta-analysis
Int J Clin Exp Med 2016;9(5):8334-8340 www.ijcem.com /ISSN:1940-5901/IJCEM0021458 Original Article Dietary nitrite and nitrate is not associated with adult glioma risk: a meta-analysis Peng Wang 2*, Chong-Xian
More informationCochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library)
A systematic review of smoking cessation and relapse prevention interventions in parents of babies admitted to a neonatal unit (after delivery) Divya Nelson, Sarah Gentry, Caitlin Notley, Henry White,
More informationRisk factors for the initiation and aggravation of lymphoedema after axillary lymph node dissection for breast cancer
HEALTH SERVICES RESEARCH FUND Risk factors for the initiation and aggravation of lymphoedema after axillary lymph node dissection for breast cancer Key Messages 1. Previous inflammation or infection of
More informationAssociation between dietary protein intake and prostate cancer risk: evidence from a meta-analysis
Mao et al. World Journal of Surgical Oncology (2018) 16:152 https://doi.org/10.1186/s12957-018-1452-0 RESEARCH Open Access Association between dietary protein intake and prostate cancer risk: evidence
More informationSupplementary Online Content
Supplementary Online Content The Premenopausal Breast Cancer Collaborative Group. Association body mass index and age with premenopausal breast cancer risk in premenopausal women. JAMA Oncol. Published
More informationAnalysing research on cancer prevention and survival. Diet, nutrition, physical activity and breast cancer survivors. In partnership with
Analysing research on cancer prevention and survival Diet, nutrition, physical activity and breast cancer survivors 2014 In partnership with Contents About World Cancer Research Fund International 1 Our
More informationRole of CASP-10 gene polymorphisms in cancer susceptibility: a HuGE review and meta-analysis
Role of CASP-10 gene polymorphisms in cancer susceptibility: a HuGE review and meta-analysis S. Yan, Y.Z. Li, J.W. Zhu, C.L. Liu, P. Wang and Y.L. Liu Department of Urological Surgery, Fourth Affiliated
More information1. Study Title. Exercise and Late Mortality in 5-Year Survivors of Childhood Cancer: a Report from the Childhood Cancer Survivor Study.
CCSS Analysis Concept Proposal Exercise, Mortality, & Childhood Cancer 1 1. Study Title. Exercise and Late Mortality in 5-Year Survivors of Childhood Cancer: a Report from the Childhood Cancer Survivor
More informationXRCC3 T241M polymorphism and melanoma skin cancer risk: A meta-analysis
ONCOLOGY LETTERS 9: 2425-2429, 2015 XRCC3 T241M polymorphism and melanoma skin cancer risk: A meta-analysis JINGHUA FAN 1, YUHUA FAN 2, XIAOXIAO KANG 1 and LIMIN ZHAO 1 1 Department of Dermatology, Xi'an
More informationCancerous esophageal stenosis before treatment was significantly correlated to poor prognosis of patients with esophageal cancer: a meta-analysis
Original Article Cancerous before treatment was significantly correlated to poor prognosis of patients with cancer: a meta-analysis Han-Yu Deng 1,2#, Guha Alai 1#, Jun Luo 1#, Gang Li 1, Ze-Guo Zhuo 1,
More informationReview Article Association between HLA-DQ Gene Polymorphisms and HBV-Related Hepatocellular Carcinoma
Hindawi Gastroenterology Research and Practice Volume 2017, Article ID 7150386, 11 pages https://doiorg/101155/2017/7150386 Review Article Association between HLA-DQ Gene Polymorphisms and HBV-Related
More information