CIGNA HealthCare Prior Authorization Form - Growth Hormone Medications -

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1 Pharmacy Services Phone: (800) Fax: (800) CIGNA HealthCare Prior Authorization Form - Growth Hormone Medications - Notice: Failure to complete this form in its entirety may result in delayed processing or an adverse determination for insufficient information. * Provider Name: Specialty: PROVIDER INFORMATION * DEA or TIN: PATIENT INFORMATION **Due to privacy regulations we will not be able to respond via fax with the outcome of our review unless all asterisked (*) items on this form are completed** Office Contact Person: * Patient Name: Office Phone: * CIGNA ID: Office Fax: * Date Of Birth: * Is your fax machine kept in a secure location? * May we fax our response to your office? * Patient Street Address: Office Street Address: City State Zip City State Zip Patient Phone: Medication requested: Medication name: Strength: Dose (mg/kg): Frequency of administration: Patient s current weight: Where will this medication be obtained? CIGNA Tel-Drug (CIGNA's nationally preferred specialty pharmacy) Retail pharmacy Prescriber s office stock (billing on a medical claim form) Home Health / Home Infusion vendor Please specify the following: Has this patient been treated with growth hormone in the past? If Yes, what was the patient s pre-treatment age? If Yes, what date was growth hormone therapy started? Questions for Pediatric Patients (for Adult patients, see page 4 of this form) Has this patient been evaluated by an endocrinologist (initially and annually)? What was the patient s pre-treatment height? What was the patient s pre-treatment height velocity Are the patient s epiphyses open? CIGNA HealthCare Prior Authorization Form Growth Hormone Medications Page 1 of 5

2 Growth Hormone Deficiency in Children Does this patient have any of the following CNS pathology? Please check any options that apply: Hypoplasia of pituitary gland Empty sella syndrome Craniofacial developmental defects Septo-optic dysplasia Interruption of pituitary stalk Pituitary or hypothalamic tumors History of irradiation Multiple pituitary hormone deficiency Proven genetic defect affect growth hormone axis Has this patient had a growth hormone response of less than 10ng/mL to at least TWO provocative stimuli? Please note that only 1 stim test is required for children with CNS pathology. Which provocative stimuli tests were performed? Please specify the date and lab value of tests performed. Insulin Stimuli Lab Value Date Taken Levodopa L-Arginine Clonidine Glucagon Have other pituitary hormone deficiencies been ruled out or corrected (including thyroid, cortisol and sex hormones)? Small for Gestational Age Please attach growth curve charts and include all lab levels. What was this patient s gestational age? What was this patient s birth weight? What was this patient s birth length? What was this patient s height at age 2? Please attach growth curve charts. Growth Delay Secondary to Chronic Kidney Disease Does this patient have renal function at stage 2 chronic kidney disease (or GFR from ml/min/1.73m 2 )? Please attach growth curve charts. CIGNA HealthCare Prior Authorization Form Growth Hormone Medications Page 2 of 5

3 Turner s Syndrome Has the diagnosis of Turner s Syndrome been established by genetic testing? Yes No Please note that documentation of genetic testing is required for review of this request. Please attach growth curve charts and documentation of genetic testing. Panhypopituitarism Which of the following anterior pituitary hormones are absent in this patient? Please mark all that apply. Luteinizing Hormone (LH) Follicle Stimulating Hormone (FSH) Thyroid Stimulating Hormone (TSH) Androcorticotropic Hormone Which hormones are being supplemented? Prader-Willi Syndrome Please attach chart notes with lab levels. Has the diagnosis of Prader-Willi Syndrome been confirmed by appropriate genetic testing? Please attach growth curve charts and include all lab levels. Noonan Syndrome Has the diagnosis of Noonan s syndrome been established by genetic testing or in consultation with a geneticist? Please attach growth curve charts. Other Diagnosis (please specify below) What is the patient s diagnosis? (Check all that apply) Crohn s disease Down Syndrome Idiopathic Short Stature of Unknown Origin Intrauterine Growth Restriction (IUGR) Juvenile Rheumatoid Arthritis Non-Growth Hormone Deficient Short Stature Osteogenesis imperfecta Precocious puberty Russell-Silver Syndrome Skeletal dysplasia, such as achondroplasia CIGNA HealthCare Prior Authorization Form Growth Hormone Medications Page 3 of 5

4 Questions for Adult Patients Adult Growth Hormone Deficiency Has this patient been evaluated by an endocrinologist? Is this patient s growth hormone deficiency a result of documented childhood growth hormone deficiency? Is this patient s growth hormone deficiency a result of any of the following conditions? (Mark all that apply) Destructive hypothalamic disease Destructive pituitary disease Radiation therapy Surgery (please provide details about the procedure) Trauma (please provide details about the nature of trauma) Has this patient had a growth hormone response of less than 5ng/mL to at least ONE provocative stimulus? Which provocative stimuli tests were performed? Please specify the date and lab value of tests performed. Insulin Stimuli Lab Value Date Taken Levodopa L-Arginine Clonidine Glucagon Arginine-GHRH Have other pituitary hormone deficiencies (thyroid, cortisol and sex hormones) been ruled out or corrected? Please attach chart notes with lab values. Multiple Pituitary Hormone Deficiencies / Panhypopituitarism Has this patient been evaluated by an endocrinologist? Which of the following anterior pituitary hormones are absent in this patient? Please mark all that apply. Luteinizing Hormone (LH) Follicle Stimulating Hormone (FSH) Thyroid Stimulating Hormone (TSH) Androcorticotropic Hormone Please attach chart notes with lab values and details of hormonal replacement therapy. CIGNA HealthCare Prior Authorization Form Growth Hormone Medications Page 4 of 5

5 AIDS Wasting (Serostim Only) What was the patient s pre-treatment baseline body weight? What is the patient s current body weight? What is the patient s current body mass index? Has this patient had failure to treatment with, or contraindication or intolerance to appetite stimulants and/or other anabolic agents? (Please provide medication details in the Details section.) Will this patient have continuous use of antiviral therapy? Short Bowel Syndrome (Zorbtive Only) Please attach chart notes with lab values. Will this medication be used with a special diet AND glutamine supplementation? Is this patient dependant on intravenous parenteral nutrition? Please attach chart notes supporting this request. Other Diagnosis (please specify below) What is the patient s diagnosis? (Check all that apply) Crohn s Disease Increased Athletic Performance Infertility Muscular Dystrophy Obesity Osteoporosis Somatopause CIGNA HealthCare s coverage position on this and other medications may be viewed online at: Please fax completed form to (800) Due to the clinical information required, requests for Growth Hormone medications cannot be accepted via phone. Our standard response time for prescription drug coverage requests is 2-4 business days. If your request is urgent, it is important that you call Pharmacy Services to have the request expedited. View our formulary on line at CIGNA Pharmacy Management or CIGNA HealthCare refer to various operating subsidiaries of CIGNA Corporation. Products and services are provided by these subsidiaries and not by CIGNA Corporation. These subsidiaries include Connecticut General Life Insurance Company, Tel-Drug, Inc., Tel-Drug of Pennsylvania, L.L.C., and HMO or service company subsidiaries of CIGNA Health Corporation. V CIGNA HealthCare Prior Authorization Form Growth Hormone Medications Page 5 of 5

2. Has this plan authorized this medication in the past for this member (i.e., previous authorization is on file under this plan)?

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