Daniel J Escudero, PhD

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Daniel J Escudero, PhD Research Associate T.H. Chan School of Public Health Tel: (617) 432-1899 (office); (551) 404-7592 (cell) Email: Escudero@hsph.harvard.edu 1. EDUCATION AND POSTDOCTORAL TRAINING Postdoctoral Fellowship 2016-2018 T.H. Chan School of Public Health Boston, MA Ph.D. (Epidemiology) 2011-2016 School of Public Health Thesis: The use of antiretrovirals for preventing HIV among people who inject drugs Advisors: Dr. Brandon Marshall, Dr. Mark Lurie M.P.H. (Health Policy) 2008-2010 Rollins School of Public Health Atlanta, GA Emory University B.A. (Political Science) 2002-2006 College of Liberal Arts and Sciences University Park, PA Penn State University 2. EMPLOYMENT and POSITIONS Research Associate Instructor 2018-Present Boston, MA 2017-Present Boston, MA Predoctoral Epidemiology Fellow 2013-2014 Pfizer, Inc Groton, CT Research Assistant 2011-2013

Health Policy Analyst 2010-2011 National Committee on Quality Assurance (NCQA) Washington, DC HIV/AIDS Analyst 2008-2010 Global AIDS Program Atlanta, GA Centers for Disease Control and Prevention (CDC) 3. PUBLICATIONS A. REFEREED JOURNAL ARTICLES Escudero DJ, Lurie MN, Mayer KH, King M, Galea S, Friedman SR, Marshall BDL. The risk of HIV transmission at each step of the HIV care continuum among people who inject drugs: A modeling study. BMC Public Health, 2017 Jul 25;17(1):614 Shangani S, Escudero D, Kipruto K, Harrison A, Marshall B, Operario D. Effectiveness of peer-led interventions to increase HIV testing among men who have sex with men: A systematic review and metaanalysis. AIDS Care, 2017 Aug;29(8):1003-1013 Escudero DJ, Lurie MN, Mayer KH, Weinreb C, King M, Galea S, Friedman SR, Marshall BDL. Acute HIV infection transmission among people who inject drugs in a mature epidemic setting. AIDS, 2016. doi: 2016 Oct 23;30(16):2537-2544 Escudero DJ, Marshall BDL, Kerr T, Hayashi K, Feng C, Guillemi SA, Hogg RS, Montaner J, Wood E, Milloy MJ. No association between HIV Status and Risk of non-fatal overdose among people who inject drugs in Vancouver, Canada. Addictive Behaviors, 2016. doi: 10.1016/j.addbeh.2016.03.029 Monteiro, JFG, Escudero, DJ, Weinreb, C, Galea, S, Friedman, SR, Flanigan, T, Marshall, BD. Understanding the effects of different HIV transmission models in individual-based microsimulation of HIV epidemic dynamics among people who inject drugs. Epidemiology and Infection, 2016. doi:10.1017/s0950268815003180 Escudero DJ, Kerr T, Operario D, Socias ME, Sued O, Marshall BDL. Inclusion of Trans Women in Pre- Exposure Prophylaxis (PrEP) Trials: A Review. AIDS Care, 2014 Nov 28: 1-5. doi: 10.1080/09540121.2014.986051 Escudero DJ, Lurie MN, Howe CJ, Kerr T, Marshall BDL. HIV Pre-exposure prophylaxis (PrEP) for people who inject drugs: A review of current results and agenda for future research. Journal of the International AIDS Society. 2014;17:18899. doi: 10.7448/IAS.17.1.18899 Escudero DJ, Kerr T, Wood E, Nguyen P, Lurie MN, Sued O, Marshall BDL. Acceptability of HIV Preexposure Prophylaxis (PREP) Among People Who Inject Drugs (PWID) in a Canadian Setting. AIDS and Behavior, 2014. doi: 10.1007/s10461-014-0867-z Monteiro, JFG, Marshall BDL, Escudero D, Sosa-Rubi SG, Gonzalez A, Flanigan T, Operario D, Mayer KH, Lurie MN, Galarraga O. Preventing HIV Transmission Among Partners of HIV-Positive Male Sex Workers in Mexico City: A Modeling Study. AIDS and Behavior, 2014. doi: 10.1007/s10461-014-0915-8

B. WORK UNDER REVIEW Escudero DJ, Marukutira T, McCormick A, Makhema J, Seage GR. Should Botswana Expand Free Antiretroviral Therapy to Migrants? Submitted to Lancet: HIV Escudero DJ, Bennett B, Kenneally S, Darrow WW, Mayer KH, Seage GR. Progress and Challenges in Getting to Zero New HIV Infections in Miami, Florida. Submitted to Public Health Reports C. ABSTRACTS Escudero D, Marukutira T, McCormick A, Seage G. The need to improve HIV care for migrant populations in Botswana: addressing the unknowns. The 22 nd International AIDS Conference. July, 2018, Amsterdam, the Netherlands. Abstract number: A-899-0189-04302. Escudero DJ, Lurie MN, Mayer KH, King M, Galea S, Friedman SR, Marshall BDL. The risk of HIV transmission at each step of the HIV care continuum among people who inject drugs. The 8th IAS Conference on HIV Pathogenesis, Treatment and Prevention. July, 2017, Paris, France. Abstract number: A-854-0202-01044 Shangani S, Escudero D, Kipruto K, Harrison A, Marshall B, Operario D. Peer-led interventions to increase HIV testing among men who have sex with men: A systematic review. APHA 2016 Annual Meeting and Expo. November, 2016, Denver, Colorado. Abstract number: 359240. Monteiro JF, Escudero D, Weinreb C, Flanigan T, Galea S, Friedman SR, Marshall BDL. Understanding the effects of different HIV transmission models in individual-based microsimulation of HIV epidemic dynamics among people who inject drugs. The 8th IAS Conference on HIV Pathogenesis, Treatment and Prevention. July, 2015, Vancouver, Canada. Abstract number: A-729-0193-00946. Escudero DJ, Marshall BDL, Kerr T, Feng C, Guillemi, Hogg R, Montaner J, Wood E, Milloy MJ. No association between HIV serostatus and risk of non-fatal overdose among people who inject drugs within the ACCESS and VIDUS2 cohorts in British Columbia. The 8th IAS Conference on HIV Pathogenesis, Treatment and Prevention. July, 2015, Vancouver, Canada. Abstract number: A-729-0212-01163. Escudero DJ, Kerr T, Operario D, Socias ME, Sued O, Marshall BD. Inclusion of Transgender Persons in Pre-Exposure Prophylaxis (PrEP) Trials: A Review. International AIDS Society: AIDS 2014, Melbourne, Australia. July 2014. Abstract no. LBPE24 Escudero DJ, Weinreb C, Lurie MN, Mayer K, Galea S, Friedman S, Marshall BD. Acute HIV infection transmission among people who inject drugs in an established epidemic setting. Conference on Retroviruses and Opportunistic Infections (CROI) 2015, Seattle, WA. February 2015. Abstract no. 2100572 Escudero DJ, Kerr T, Wood E, Nguyen P, Lurie MN, Sued O, Marshall BD. Acceptability of HIV preexposure prophylaxis (PrEP) among people who inject drugs (PWID) in Vancouver, Canada. International AIDS Society: AIDS 2014, Melbourne, Australia. July 2014. Abstract no. THPE091 Escudero DJ, Lurie, MN, Howe, CJ, Marshall BD. A systematic review of HIV pre-exposure prophylaxis (PrEP) among injection drug users. IAPAC: Controlling the HIV Epidemic with Antiretrovirals, London, UK. September 2013. Abstract no. 63

Escudero DJ, Lurie MN, Weinreb C, Mayer KH, Friedman SR, Galea S, Marshall BD. The contribution of transmission from acute HIV infection may vary by epidemic stage among people who inject drugs. The 8th IAS Conference on HIV Pathogenesis, Treatment and Prevention. July, 2015, Vancouver, Canada. Abstract number: A-729-0193-01739. D. ABSTRACTS UNDER REVIEW None Currently 4. MEMBERSHIPS WITH PROFESSIONAL ORGANIZATIONS & SOCIETIES 1) International AIDS Society (2011 Present) 2) International Antiviral Society USA (2015-Present) 3) New England HIV Implementation Science Network (2014-Present) 5. AWARDS AND ACHIEVEMENTS 1) National Institute of Allergy and Infectious Disease (NIAID) Postdoctoral Fellowship (T32) at (2016-2018) 2) CROI Young Investigator Scholarship (2014) 3) National Institute on Drug Abuse Predoctoral Fellowship (F-31) at (2014-2016) 4) Graduate School International Travel Fund Award (2014) 5) CFAR Trainee Support Award, Lifespan/Tufts/Brown Center for AIDS Research (2013) 6) Undergraduate Academic Scholarship, Penn State University (2002-2006) 6. SERVICE A. UNIVERSITY OR DEPARTMENTAL 1) Member, Curriculum Committee, (2014-2016) 2) Co-Chair, Academic Subcommittee, School of Public Health Graduate Student Council, Brown University (2014-2015) 3) Global Health and HIV/AIDS Project Facilitator, Brown International Advanced Research Institutes (BIARI 2012) 4) Student Senator, Rollins School of Public Health University Senate, Emory University (2009-2010) B. JOURNAL REVIEW 2014-Present: PLoS One, JIAS, Drug and Alcohol Dependence C. COMMUNITY 1) Mentor to Central Falls High School Science Olympiad team (2012)

7. TEACHING EXPERIENCE A. COURSE INSTRUCTION Instructor 2017 EPI 256 Epidemiology of HIV Infection: Design and Conduct of Prevention Interventions Boston, MA Teaching Assistant 2015 PHP 1854 The Epidemiology and Control of Infectious Diseases Teaching Assistant 2015 PHP 2220H Methodological Issues in the Epidemiology, Treatment, Prevention of HIV Teaching Assistant 2014 PHP 1854 The Epidemiology and Control of Infectious Diseases Teaching Assistant 2014 PHP 0850 Fundamentals of Epidemiology Teaching Assistant 2012 PHP 1070 Global Burden of Disease B. INVITED AND GUEST LECTURES Using individual-based epidemiologic modeling to estimate the effectiveness of the Miami Getting to Zero HIV campaign. University of Pennsylvania CCEB Seminar Series. Sept 13, 2018 Global Infectious Disease Epidemiology and Epidemic Growth. PHP 2120 (Introduction to Methods in Epidemiologic Research). Oct 4, 2016 Introduction to Infectious Disease Epidemiology and Transmission. PHP 2120 (Introduction to Methods in Epidemiologic Research). Sep 15, 2016 Screening. PHP 2120 (Introduction to Methods in Epidemiologic Research). Oct 27, 2015 Measurement and Measures of Infectious Disease Occurrence. PHP 1854 (The Epidemiology and Control of Infectious Diseases). Sept 14, 2015 Introduction to Epidemic Modelling of HIV and Other Infectious Diseases. PHP 2220H (Methodological Issues in the Epidemiology, Treatment, and Prevention of HIV). April 6, 2015

Screening. PHP 2120 (Introduction to Methods in Epidemiologic Research). Oct 21, 2014 Measurement and Measures of Infectious Disease Occurrence. PHP 1854 (The Epidemiology and Control of Infectious Diseases). Sept 15, 2014 Screening. PHP 2120 (Introduction to Methods in Epidemiologic Research). Oct 22, 2013 Epidemiologic Research Methods in Global Public Health. PHP 1070 (Global Burden of Disease). Sept 12, 2012 8. RESEARH SUPPORT A. ONGOING RESEARCH SUPPORT Using agent-based modeling to estimate the effectiveness of the Miami Getting to Zero HIV campaign (Escudero) Role on Project: Principal Investigator $636,255 Dates: February 22, 2018 February 21, 2023 Funder: National Institutes of Health (National Institute of Allergy and Infectious Diseases) Project Identifier: K01-AI138863 Description: The proposed research seeks to use agent-based epidemiologic modeling to estimate the impact of the HIV elimination campaign in Miami, FL, termed Getting to Zero. The Miami metropolitan area is home to one of the most highly-burdened and growing HIV epidemics in the country, and results of this work will provide estimates for critical epidemiologic outcomes following implementation of the elimination campaign, as well as suggest the likelihood or timetable for the elimination of new infections. Estimating the effectiveness of the Miami Getting to Zero HIV campaign (Escudero) Role on Sub-Project: Principal Investigator $71,713 Dates: April 1, 2018 March 31, 2019 Funder: NIAID via Harvard Center for AIDS Research (CFAR) Project Identifier: P30-AI060354 (Walker) Description: The proposed research seeks to perform preliminary analyses, parameterization, and calibration needed to complete the objectives of a K01 proposal, with a goal to use agent-based modeling to estimate the effectiveness of the Miami Getting to Zero HIV campaign. The Miami metropolitan area is home to one of the most highly-burdened and growing HIV epidemics in the country, and results of this work will provide estimates for critical epidemiologic outcomes following implementation of the elimination campaign, as well as suggest the likelihood or timetable for the elimination of new infections. B. COMPLETED SUPPORT Program for AIDS clinical research training (Freedberg) Role on Project: Trainee $74,709 Dates: June 29, 2016 Feb 21, 2018 Funder: National Institutes of Health (National Institute of Allergy and Infectious Diseases) Project Identifier: T32-AI007433 Description: This HIV T32 has three specific aims for its trainees: 1) To acquire a sufficient body of knowledge of quantitative methods to conduct independent research in: clinical epidemiology, clinical

trials, cost-effectiveness analysis, outcomes research, and/or implementation science. 2) To foster the creation of important scientific contributions with the close and longitudinal mentorship of program faculty. 3) To develop a primary research focus and a broad understanding of the various aspects of HIV disease for novel interdisciplinary research. Estimating the impact of acute-stage HIV transmission among drug users (Escudero) Role on Project: Principal Investigator $85,796 Dates: June 1, 2014 May 31, 2016 Funder: National Institutes of Health (National Institute on Drug Abuse) Project Identifier: F31-DA037808 Description: A study to estimate the contribution of acute-stage HIV transmission to total new HIV cases among drug users, and in doing so estimate the effects of prevention strategies on eliminating HIV transmission within this population.