State of Wyoming. Department of Health

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State of Wyoming Department of Health Colorectal Cancer in Wyoming: Issue Brief Thomas O. Forslund, Director March 2012 The Issue Brief of Colorectal Cancer in Wyoming is published by the Public Health Division Wendy E. Braund, MD, MPH, MSEd, FACPM, State Health Officer and Senior Administrator Additional information and copies may be obtained from: Carol E. Peterson, MS, RN Colorectal Cancer Screening Program Wyoming Department of Health 6101 Yellowstone Road, Suite 510 Cheyenne, WY 82002 Telephone: (307) 777-6006 Facsimile: (307) 777-1950 E-mail: carol.peterson@wyo.gov This document is available in alternative format upon request.

Celebrating Five Years of Prevention The Wyoming Colorectal Cancer Screening Program (WCCSP) is state-funded through tobacco settlement funds appropriated by the Wyoming Legislature. The program began on July 1, 2007. Since its inception, the WCCSP has received outstanding support from the Wyoming Breast and Cervical Cancer Early Detection Program, the Wyoming Comprehensive Cancer Control Consortium and the Wyoming Cancer Resource Services regional projects. In 2012, the program is celebrating five years of serving as a significant player in the early detection of colorectal cancer in Wyoming. As of March 1, 2012, over 2,000 Wyoming residents had received a colonoscopy through the program. Wyoming Department of Health Commit to your health. Introduction Colorectal cancer is the second leading cause of cancer death in Wyoming, second only to lung cancer and yet, it is very preventable with screening. A recent study published in the New England Journal of Medicine found that removing precancerous polyps during colonoscopies reduced the risk of dying from colorectal cancer by 53%. According to the Wyoming Behavioral Risk Factor Surveillance System (BRFSS), colorectal cancer screening rates are increasing in Wyoming. In 2006, 52.6% of Wyoming adults aged 50 and older reported they had ever had a colonoscopy and/or sigmoidoscopy. By 2010 the rate had increased to 59.3%. In 2009, 234 new cases of colorectal cancer were diagnosed in Wyoming. Of the 234 new cases, 123 were males and 111 were females. There were 76 deaths (43 males, 33 females) due to colorectal cancer in 2009. The Wyoming Cancer Control Act, passed in 2007, legislated a comprehensive cancer control plan for Wyoming. As a part of this act, the Wyoming Colorectal Cancer Screening Program (WCCSP) was established. Barriers to colorectal screening include uninsurance and high insurance deductibles and/or co-payments. The WCCSP helps eliminate the cost barriers to screening and provides free colonoscopies to eligible Wyoming residents. The American Cancer Society estimates that there will be 240 new colorectal cancer cases and 90 deaths due to colorectal cancer in Wyoming in 2012. 2

Colorectal Cancer Rates Despite strong evidence supporting the effectiveness of colorectal screening, only about half the country s population aged 50 and over are current for recommended screenings. According to the National Cancer Institute, colorectal cancer rates have been declining over the last 20 years among adults 50 years and older. During the same time frame, the incidence of colorectal cancer has been increasing among adults younger than 50 years old. Exact reasons for this increase are unknown, but may reflect trends in obesity and/or unfavorable dietary patterns in children and young adults. Since 1998, mortality rates overall have decreased 2.8% per year in men and 2.6% per year in women. Screening Early colorectal cancer often has no symptoms, which is why screening is so important. The screening process for colorectal cancer (sigmoidoscopy or colonoscopy) is very effective and can result in the identification and removal of polyps before they become cancerous as well as the detection of cancer that is at an early stage. Screening Rates by County Listed below are percentage rates for adults aged 50 and older by county who have never had a sigmoidoscopy or colonoscopy. (BRFSS - combined data 2005-2009, smallest two counties combined) Albany 33.7% Lincoln 50.0% Big Horn 50.3% Natrona 37.5% Campbell 44.6% Park 35.8% Carbon 51.1% Platte 41.1% Converse 41.9% Sheridan 28.9% Crook 53.5% Sublette 37.8% Fremont 46.5% Sweetwater 47.6% Goshen 45.0% Teton 33.8% Hot Springs/ Niobrara 49.6% Uinta 50.4% Washakie 47.8% Johnson 39.4% Weston 43.4% Laramie 36.5% State Average 39.5% U.S. Average = 37.8 (2008) % of adults screened 70 60 50 40 30 20 10 1995 1997 1999 2001 2003 2004 Year Source: Wyoming Behavioral Risk Factor Surveillance System 2006 2008 2009 2010 US * US* = US Median 2010 HP** = Healthy People 2020 goal HP ** Figure 1: Wyoming Colorectal Cancer Screening Rates: adults 50 and older having ever received a colonoscopy or a sigmoidoscopy 3

Wyoming Screening Rates by Groups According to 2010 BRFSS data, colonoscopy screening rates in Wyoming are lowest among: Adults with no personal doctor or medical home (24.5%) Uninsured adults (29.2%) Adults with no medical check-up in past two years (30.2%) Adults with less than a high school education (33.8%) Smokers (35.5%) Adults ages 50-54 (36.0%) By comparison, colonoscopy screening rates are highest among: Adults ages 65-74 (62.3%) Adults with a medical check-up in past two years (57.5%) College graduates (56.5%) Adults with a personal doctor or medical home (56.0%) Non-smokers (54.6%) Insured adults (53.6%) Wyoming Colorectal Cancer Incidence and Mortality 300 Number of adults 250 200 150 100 50 Incidence Deaths 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 Year Figure 2: Wyoming Colorectal Cancer Incidence and Mortality: all ages and all races 4

Wyoming Colorectal Cancer Survival Rates Relative survival is a measure representing cancer survival in the absence of other causes of death. It is defined as the ratio of the proportion of observed survivors in a group of cancer patients to the proportion of expected survivors in a comparable set of cancer-free individuals. Listed below are the 2009 colorectal cancer survival rates in Wyoming. Length of time Survival Rate 12 months 82.9% 24 months 74.4% 36 months 68.5% 48 months 64.4% 60 months 61.7% Five-year survival rates vary depending on the stage of diagnosis. Listed below are the U.S. five-year relative survival rates for colorectal cancer (2001-2007). Survival Stage of Diagnosis Rate Localized (confined to primary site) 90.1% Regional (spread to regional lymph nodes) 69.2% Distant (cancer has metastasized) 11.7% 2009 Wyoming Colorectal Cancer by Stage Regional - 29% Distant - 20% Local - 42% In situ-5% Unstaged -4% 2009 Colorectal Incidence and Mortality Rates WY male incidence rate 46.4* US male incidence rate 51.8* WY female incidence rate 36.6* US female incidence rate 38.5* WY male mortality rate 15.5* US male mortality rate 19.0* WY female mortality rate 12.4* US female mortality rate 13.4* *Rates are per 100,000 Risk Factors The risk of colorectal cancer increases with age, with 91% of cases being diagnosed in individuals age 50 and older. Colorectal cancer risk is increased by certain inherited genetic mutations, a personal or family history of colorectal cancer and/or polyps or a personal history of chronic inflammatory bowel disease. Studies have also shown an association between diabetes and colorectal cancer. There are several factors connected to the increased risk of colorectal cancer that can be impacted through personal lifestyle changes. These include: obesity physical inactivity a diet high in processed and red meat heavy alcohol consumption inadequate intake of fruits and vegetables smoking Studies show that compared to healthy weight individuals, men and women who are overweight are more likely to develop colorectal cancer and die from the disease. According to the American Cancer Society, milk and calcium consumption may decrease the risk of colorectal cancer. 5

Screening Recommendations Colorectal cancer usually develops slowly over a period of ten to 15 years. Screening has the potential to prevent colorectal cancer because most colorectal cancers develop from polyps. Polyps are noncancerous growths in the colon and rectum. Certain kinds of polyps, called adenomatous polyps or adenomas are the most likely to become cancers, though fewer than ten percent of adenomas progress to cancer. Adenomas are common. An estimated one-third to one-half of adults will develop one or more adenomas in their lifetime. Removing polyps through a screening colonoscopy can prevent cancer from occurring. Additionally, being screened at the recommended frequency increases the likelihood that when cancer is present, it will be detected at an earlier stage when it is more likely to be cured with less extensive treatment and recovery occurring much faster. Wyoming Screening Recommendations: The Wyoming Cancer Control Plan recommends colorectal cancer screening beginning at age 50 with a colonoscopy every 10 years. Immunochemical testing should be done annually beginning at age 50. Rescreening more frequently than every 10 years may be recommended based on results of first colonoscopy. Individuals are encouraged to talk with their healthcare provider about screening before age 50 if they have a family history of colon cancer. African Americans should begin screening at age 45. WCCSP Eligibility Requirements Eligibility criteria for a free colonoscopy through the Wyoming Colorectal Cancer Screening program include: 50 years and older and not eligible for the Federal Medicare program Younger than 50 if medical criteria are met Minimum age of 18 Must be a Wyoming resident for at least one year prior to application Income at or below 250% of Federal Poverty Level Uninsured or underinsured for colorectal cancer screening The WCCSP currently screens about 480 patients per year at an average cost of $1,800 per procedure. The program has over 300 contracted healthcare providers statewide including physicians, hospital/surgical centers, pathologists, and anesthesiologists. For more information, call 1-866-205-5292 or visit the program s website at www. health.wyo.gov/phsd/ccp. Sources: 2011-2013 American Cancer Society: Colorectal Cancer Facts and Figures 2010 Behavioral Risk Factor Surveillance System, Wyoming Department of Health 2010 Wyoming Colorectal Cancer Screening Program internal data 2010 colorectal cancer data from the Wyoming Cancer Surveillance Program (a statewide population-based cancer registry) 1992-2007 Surveillance, Epidemiology, and End Results Program, National Cancer Institute New England Journal of Medicine 2012; 366:687-696, Feb. 23, 2012 Colorectal Cancer in Wyoming: Issue Brief 6