Priority diseases in Europe, including transparency aspects

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GF-TADs for Europe Seventh Regional Steering Committee meeting (RSC7) Priority diseases in Europe, including transparency aspects AFSCA - Brussels 16-17 October 2017 Dr Paula Cáceres Soto Head, World Animal Health Information and Analysis Department, OIE

CONTENT 1. Priority animal diseases in Europe reported to the OIE African swine fever Lumpy skin disease Infection with influenza A viruses of high pathogenicity Infection with foot and mouth disease virus Infection with peste des petits ruminants virus Infection with classical swine fever virus Infection with rabies virus Infection with Brucella abortus, Brucella melitensis and Brucella suis 2. Transparency and notification 3. WAHIS is becoming WAHIS+

African swine fever

Reported distribution of ASF in 2016 and 2017 (data based on reports received up to 15 September 2017) 10 countries Czech Republic: 1st occurrence starting from June 2017 Romania: 1st occurrence starting from July 2017 Moldova: 1st occurrence starting from September 2016

Disease trend graph (data based on reports received up to 15 September 2017) Deterioration

Analysis of WAHIS data Evolution of proportion of outbreaks notified in domestic pigs vs. wild boars?

Methodology 2005-1 st sem. 2017 Nearly 9000 outbreaks in reported through WAHIS Categorisation domestic pigs & wild boars Numbers with years Proportions with years

Results (1) No. outbreaks by category Continuous increase of the number of outbreaks

Results (2) - % outbreaks reported in domestic pigs only Decrease of the proportion of outbreaks reported in domestic pigs

Chapter 1.1.: Notification of diseases, infections and infestations, and provision of epidemiological information (Article 1.1.3) Veterinary Authorities shall, under the responsibility of the Delegate, send to the HQ, in accordance with relevant provisions in the disease-specific chapters, notification, through the WAHIS or by fax or email within 24 hours, of any of the following events: FIRST OCCURRENCE of a LDII in a country, a zone or a compartment; RECURRENCE of a LDII in a country, a zone or a compartment ; first occurrence of a NEW STRAIN of a pathogenic agent of a LDII in a country, ; a sudden and UNEXPECTED CHANGE in the distrib. or increase in incidence or virulence of, or morbidity or mortality caused by, the pathogenic agent of a LDII pres... occurrence of a LDII in an UNUSUAL HOST SPECIES; WEEKLY REPORTS subsequent to a notification under point 1) above, to provide further information on the evolution of the event which justified the notification. These reports should continue until the DII HAS BEEN ERADICATED OR THE SITUATION HAS BECOME SUFFICIENTLY STABLE so that six-monthly reporting under point 3) will satisfy the obligation of the Member Country; for each event notified, a final report should be submitted; LDII= listed disease, infection or infestation

Country Outbreaks in on-going events Czech Republic 114 Latvia 697 Poland 630 Romania 2 Russia 598 Ukraine 127 Estonia 1052 (sufficiently stable in April 2016) Lithuania 821 (sufficiently stable in September 2017) When the situation is consider sufficiently stable, no more follow-up reports will be sent through WAHIS and the information about this disease will be included in the next six-monthly reports.

Conclusions Deterioration of the situation related to the number of countries affected Increased number of outbreaks reported trough WAHIS Decreased proportion of outbreaks reported in domestic pigs In order to facilitate the reporting process, important to consider the diseases sufficiently stable and reporting through six-monthly report

Lumpy skin disease

Reported distribution of LSD in 10 countries 2016 and early 2017 (data based on reports received up to 15 September 2017)

Disease trend graph (data based on reports received up to 15 September 2017) No. countries 60 50 40 30 20 10 Deterioration % countries 40% 30% 20% 10% 0 1st sem. 2nd sem. 1st sem. 2nd sem. 1st sem. 2nd sem. 1st sem. 2nd sem. 1st sem. 2nd sem. 1st sem. 2nd sem. 1st sem. 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2nd sem. 1st sem. 2nd sem. 1st sem. 2nd sem. 1st sem. Countries reporting LSD present Countries reporting LSD absent % reporting countries affected with LSD 2nd sem. 1st sem. 2nd sem. 1st sem. 2nd sem. 1st sem. 0%

Analysis of WAHIS data Spread of the disease in the Region since 2005?

Methodology 2005-1 st sem. 2017 Nearly 2000 outbreaks in reported through WAHIS Spatial analysis based on outbreak location Kernel analysis

Results Spatial spread Kernel 2006

Results Spatial spread Kernel 2007

Results Spatial spread Kernel 2012

Results Spatial spread Kernel 2014

Results Spatial spread Kernel 2015

Results Spatial spread Kernel 2016

Results Spatial spread Kernel 2017

Conclusions Deterioration of the epidemiological situation of the Region since 2005 Disease spread to the north and to the east Control measures put in place (vaccination) is stopping the spread in 2017 (EFSA)

Infection with influenza A viruses of high pathogenicity

Reported distribution of HPAI in domestic birds in 2016 and 2017 (data based on reports received up to 15 September 2017) 26 countries Finland: 1st occurrence in the country cases in domestic birds starting from November 2016 FYRO Macedonia: 1st occurrence in the country cases in domestic birds starting from January 2017 Serbia: 1st occurrence in the country cases in domestic birds starting from December 2016

Subtypes - HPAI in domestic birds in 2016 and 2017 (data based on reports received up to 15 September 2017) Subtype No. Countries affected H5 1 H5N1 1 H5N2 1 H5N5 2 H5N6 1 H5N8 25 H5N9 1 H7N7 1

Reported distribution of HPAI in wild birds in 2016 and 2017 (data based on reports received up to 15 September 2017) 32 countries Lithuania: 1st occurrence in the country cases in wild birds starting from February 2017 Finland: 1st occurrence in the country cases in wild birds starting from November 2016 FYRO Macedonia: 1st occurrence in the country cases in wild birds starting from January 2017 Serbia: 1st occurrence in the country cases in wild birds starting from November 2016 Montenegro: 1st occurrence in the country cases in wild birds starting from December 2016

Subtypes - HPAI in wild birds in 2016 and 2017 (data based on reports received up to 15 September 2017) Subtype No. Countries affected H5 2 H5N5 10 H5N8 29

Infection with foot and mouth disease virus

Reported distribution of FMD in 2016 and 2017 (data based on reports received up to 15 September 2017) 4 countries (Armenia, Israel, Russia and Turkey) Asia 1 Serotype O was reported 9/10/17 in Respublika Bashkortostan with 3 outbreaks A, O A A, O

Infection with classical swine fever virus

Reported distribution of CSF in 2016 and 2017 (data based on reports received up to 15 September 2017) 2 countries (Latvia and Eastern part of Russia)

Infection with peste des petits ruminants virus

Reported distribution of PPR in 2016 and 2017 (data based on reports received up to 15 September 2017) 3 countries (Georgia, Israel and Turkey)

PPR in Mongolia (December 2016) More than 3000 deaths in Mongolian Saigas (critically endangered) Reinforces the need to investigate the role of wildlife in PPR epidemiology

Infection with rabies virus

Reported distribution of rabies in 2016 and 2017 19 countries (data based on reports received up to 15 September 2017) Hungary: recurrence starting from February 2017 Kazakhstan: recurrences starting from October 2016 and February 2017

Infection with Br. abortus, Br. melitensis and Br. suis

Reported distribution of B. abortus in 2016 18 countries and 2017 (data based on reports received up to 15 September 2017)

Reported distribution of B. melitensis in 2016 20 countries and 2017 (data based on reports received up to 15 September 2017)

Reported distribution of B. suis in 2016 and 2017 15 countries (data based on reports received up to 15 September 2017)

Transparency and notification

General mandate of the OIE General mandate of the OIE: to improve animal health worldwide One of the OIE s main objectives + Emerging diseases To ensure transparency in the global animal disease situation, including zoonosis. 28 203 9 116

Notification in Europe in 2017 127 immediate notifications submitted until 11 October 2017 by European countries. Six-monthly reports for 2017 submitted on : Terrestrial animal diseases 1 st semester 49% Members Aquatic animal diseases 1 st semester 43% Members

Rumours tracking activity: improvement of WAHIS sensitivity OIE tracking team 6 person Sources 250 Rumours detected Relevant rumours 20 000 3 500 Selected to track 900 130 (Early Warning) 770 (Monitoring)

Geographical tracking coverage Rumours detected in 167 countries

Evaluation of WAHIS sensitivity: early warning index Regional approach Region Higher disease reporting probability Geographical Early warning for Europe index Africa (χ2= 4.72, disparities p-value< +14% 0.05, odds ratio = 2.83) Americas +8% Asia, Far East and Oceania +8% Europe +4% Middle East +25% All Regions +8% This index estimates the increase of sensitivity due to tracking World Organisation for Animal Health Protecting animals, Preserving our future 52

WAHIS is becoming WAHIS+

Stakeholder engagement and consultation Identification of users` needs Internal users Delegates and Focal Points. March 2016 External users April 2017. On-line survey: 206 respondents from 167 countries 01 Recommendations Governance Methodology, Technical issues, Budgeting 02 Skills -Human resources On-line survey: 739 stakeholders from 143 countries 03 Consultative meetings Specialist services providers 04 WAHIS Think Tank April 2016. WAHIS+ Project team 2017 - Extensive stakeholders engagement and participation

WAHIS is becoming WAHIS+ Development of a quicker and more intuitive system with new features Extended data mining Customisable data queries Enhanced mapping features and displays Genomic data linked to epidemiological information Integration with other databases and platforms (ADIS)

Be part of the revolution in global animal health data World Organisation for Animal Health Protecting animals, Preserving our future 56

Thank you for your attention Dr Paula Cáceres Soto 12, rue de Prony, 75017 Paris, France www.oie.int media@oie.int - oie@oie.int World Organisation for Animal Health Protecting animals, Preserving our future 57