Outcomes of Laparoscopic Hysterectomy in Glangwili Hospital

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Outcomes of Laparoscopic Hysterectomy in Glangwili Hospital Anuja Joshi, Mugahid Abbasher, Islam Abdelrahman PRESENTED BY: DR ANUJA JOSHI MTI TRAINEE GLANGWILI HOSPITAL

Overview Abdominal Hysterectomy Vs Laparoscopic Hysterectomy (Literature review) Audit of Laparoscopic Hysterectomy in Glangwili Hospital Patient satisfaction survey

Milestones - 1813- Conrad Langenbeck first VH 1863- Charles Clay (Manchester) Subtotal AH These approaches remained the only two options until the latter part of the 20th century 1980s Kurt Semm suggested the use of Laparoscopic technique in hysterectomy 1989- Harry Reich- Laparoscopic-assisted vaginal hysterectomy (LAVH) 1993 Harry Reich Total Laparoscopic Hysterectomy Professor Semm

Endoscopic era - Decreased risk of incisional hernia decreased infection rate small scars-cosmetic appeal quick recovery improved QOL less blood loss less internal scarring Despite all these advantages, more laparotomies are being performed as a first line surgery in developing, and even in developed countries

Abdominal Hysterectomy (AH) vs Laparoscopic Hysterectomy (LH) - Benign Conditions Aarts et al. in 2015 1 carried out a Cochrane Systematic Review of 47 RCTs with 5102 women comparing the surgical approaches of hysterectomy in benign gynaecological disease 25 RCTs involving 2983 women specifically compared LH to AH and found that there was a quicker return to normal activities in the LH group compared to the AH group The mean difference was 13.6 days (95% CI) Also associated with Shorter duration of hospital stay Fewer wound infections Improved QoL in the first months and at 4 years post-surgery 1. Aarts JWM, Nieboer TE, Johnson N, Tavender E, Garry R, Mol BJ, Kluivers KB. Surgical approach to hysterectomy for benign gynaecological disease. Cochrane Database of Systematic Reviews 2015, Issue 8. Art. No.: CD003677. DOI: 10.1002/14651858.CD003677.pub5

Total Laparoscopic Hysterectomy (TLH) vs Total Abdominal Hysterectomy (TAH) - Endometrial Cancer Galaal et al. in 2012 1 carried out a Cochrane Systematic Review of 8 RCTs involving 3644 women comparing the above for the management of early stage endometrial cancer Women in the laparoscopy group lost significantly less blood (MD = 106.82 ml, 95% CI) & was associated with a significantly shorter hospital stay. Wang et al. in 2013 2 carried out a meta-analysis of 9 RCTs involving 1263 patients comparing the above approaches in early-stage endometrial cancer It showed that TLH was associated with overall Lower risks of major complications. 1. Galaal K, Bryant A, Fisher A, Al-Khaduri M, Kew F, Lopes A. Laparoscopy versus laparotomy for the management of early stage endometrial cancer. Cochrane Database of Systematic Reviews. 2012;. 2. Wang H, Ren Y, Yang J, Qin R, Zhai K. Total Laparoscopic Hysterectomy Versus Total Abdominal Hysterectomy for Endometrial Cancer: A Meta-analysis. Asian Pacific Journal of Cancer Prevention. 2013;14(4):2515-2519.

Cost effectiveness

Our Audit It is an ongoing study which was initiated in 2010 & is audited on yearly basis to evaluate perioperative & postoperative outcomes of Laparoscopic Hysterectomy by Mr Islam

Aim: To analyse perioperative & postoperative outcomes of Laparoscopic Hysterectomy with a specific focus on patient satisfaction Methodology: A retrospective audit of the most recent 51 cases of Laparoscopic hysterectomy. Data was collected from clinical notes & patient satisfaction surveys

Our practice Pre-op leaflets Use a team which is familiar Training theatre staff including: Position of patient, arm at sides, deep trendelenberg using yellowfins stirrups, Foam mattress to prevent cephalad migration & use of instruments. Appropriate padding in order to prevent nerve compression injuries To coagulate -we prefer use of enseal due to its nanoparticle thermostatic technology and as the lateral thermal spread is very minimal i.e 1 mm V-care manipulator Vault closure with barbed suture or interrupted vicryl Drain & catheter to be removed 6am the following day Patient discharged 24 hours later 5pm following day

1. BMI Chart Title 25 20 15 10 5 0 Cases in No 20 or less 21-30 31-40 41-50 51 and Above 7 patients with BMI > 50!!!!

2. Indication Indication Pie Chart with in 51 cases 36% 33% 31% Abnormal bleeding + PelvicPain Leiomyoma Premalignant Malignant Most of the premalignant endometrial lesions turn out to be IA & IB

3. Blood loss & drop in Hb The estimated intra-operative blood loss was less than 300ml In Studied 51 cases, 49 patients had the drop in Hb of 1-1.5 gm. Remaining 2 had Hb drop of 2.2 2.5gm No patient required blood transfusion

4. Operative time We considered operating time since patient entering the theatre till her exit from the theatre back to the recovery ward which was poorly recorded. The average operating time in our unit was 120 min which is not very accurate & we aim to correct this in the future The actual operating time was much less on average 45-90 minutes These values match with the values mentioned by NICE 1 1. Laparoscopic techniques for hysterectomy Guidance and guidelines NICE [Internet]. Nice.org.uk. 2018 [cited 15 March 2018]. Available from: https://www.nice.org.uk/guidance/ipg239/chapter/4-about-this-guidance

5. Uterine weight (from sx histology) The weight of uterus checked randomly in 11 patients ranged from 200 gm to 1300 gm. (In 3 cases out of 11 the weight was more than 1 kg) The average weight in some other studies was 1002 g (Uccella S et al 2014), 700 g (R Sinha et al 2009). The sizes of uteri (clinical assessment) ranged from normal size to 16 week size Surgical adaptations were necessary in order to facilitate the removal of larger uteri Placing port above the umbilicus Use of 30 degree scope Vaginal bisection/encoring of the uterus

6.Intra-op & post-op complications Total Cases (51) Our Audit (n=51) NICE % Donnez ET AL Bowel injury 0 2 0.06 Bladder injury 1 case 1 0.38 Ureteric injury 0 1.3 0.32 Vessel injury 0 3 0.06 Blood transfusion 0 0.97 0.06 Conversion to Laprotomy 1 case 2.79 1 vault dehiscence 0 2 0.018 PE/ DVT 1 case 1 1

7. Stay in the hospital Duration of Stay Patients 24 hours 31 2 days 12 3days 2 4 days 1 Average Length of Stay is 1.40 but majority of patients were observed to get discharged within 24 hours The prolonged stay was with patients who had a combined vaginal repair.

8.Patient satisfaction Noted from the satisfaction surveys given to patients Overall the response was very positive- praising ward staff, anesthetists & surgeons Feeling wonderful, would recommend key-hole surgery Staff were very helpful Anaesthetist was very kind and reassuring When Nursing staff and the surgeon met me on the wards postoperatively, I felt that I received personalised care for which I am grateful Fantastic surgeon, staff was wonderful and everybody was very helpful 89 % have completed the satisfaction survey & 100 % of them had received the leaflet In the majority of them it took on average 4-5 weeks for a complete recovery Learning point -2 patients wanted more emphasis on post-op care

Discussion- Maximum benefit High BMI & multiple large fibroid uterus The traumatized group of cancer patients can be benefitted with laparoscopy due to less pain & early discharge

Recommendations/future plans - Continue familiarizing theatre staff & assistant staff to the procedural steps which in turn will shorten the duration of procedure. The staff lead should be notified of the high risk cases in advance to gather a proper team. Timing of actual procedure (after position till closure of ports) should be noted & mentioned in op notes Emphasizing the importance of 1 day stay of LH patient to ward staff hence conducting the educational sessions about importance of early ambulation & discharge. To continue this yearly audit in order to reach highest standards

Last Important Survey THANK YOU