Course Title: General Pediatrics & Neonatology Pharmacotherapy

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Course Title: General Pediatrics & Neonatology Pharmacotherapy Course Number: PHPR 477 Term(s): Fall, 2016 Prerequistes: None Academic Credit (hours): 3 Category: Elective Instructor: Charles M Karnack, PharmD, BCNSP Karnack@duq.edu (412) 860-8971 Office Hours: By Appointment Only Course Description: The course provides an overview of general pediatric & neonatal pharmacotherapy. Specific areas covered include disease states of the newborn, children & adolescents as well as congenital & metabolic disorders. This course will incorporate lectures, readings, videos, participatory discussions & composition to accomplish these goals. Goals: Upon completion of this course, the enrollee will be better able to: 1. Describe the pharmacological differences between infants, children, adolescents & adults 2. Describe common neonatal & pediatric disease states 3. Evaluate neonatal & pediatric dosing on a per kilogram basis 4. Describe problems of ingestions, poisonings & child abuse 5. Discuss the neurodevelopmental disorders of autism & ADHD 6. Evaluate the pediatric pharmacotherapy literature Optional Text & Databases: Pediatric Pharmacotherapy by Sandra Benavides & Milap Nahata, American College of Clinical Pharmacy (2013) The Harriet Lane Handbook (20 th Edition) by Engorn & Flerlage, Saunders (2014) Neofax Drug Information & Pediatrics - Micromedex

Evaluation Methods Overview: Grading Policy: The course grade will consist of one journal article review or one drug formulary review (20 %) & two non cumulative exams (80%) Grading Scale: 90 & above: A 80-89: B 70-79: C 60-69: D Less than 60: F Assignment Descriptions: Journal article review: Each student can choose an article from the pediatric and/or neonatology literature & critically review it as to its content, methodology, results & conclusions (20 %) OR Drug Formulary Review: Each student can choose a medication used in pediatric and/or neonatal pharmacotherapy & describe it use, dose, contraindications/cautions, drug interactions, adverse reactions, economics & safety in pregnancy & children (20 %) Competencies: 1. Evaluate pediatric pharmacotherapy orders 2. Compile patient information to maintain a database sufficient to provide pharmaceutical care 3. Assess patient information & optimize therapy using clinical, humanistic & pharmacoeconomic information 4. Develop, implement, evaluate & modify a pharmaceutical plan of care 5. Counsel & educate patients & health care professionals 6. Collaborate with other health care professionals 7. Think critically & problem solve 8. Communicate effectively 9. Self-assess learning 10. Make & defend rational & ethical decisions Academic Integrity: The course instructor expects that all students will act with honesty & integrity while carrying out class assignments & exams. The academic integrity principle broadly states that students have done or have prepared the work or research in or out of class based on their own recollection & reasoning ability, and have given proper acknowledgement for the use of materials & sources

Course Outline: Date Aug 25 Content Introduction to Pediatric Pharmacy Practice & Pharmacotherapy Pediatric Dosing Considerations Off Label Use of Medications in Children Sep 1 Pediatric Asthma Bronchiolitis Croup Colic Sep 8 Otitis Media Cystic Fibrosis Tonsillitis Mononucleosis Sep 15 Pediatric Seizure Disorders Meningitis Metabolic Disease Sep 22 Duquesne University Presidential Inauguration (No Class) Sep 29 Autism Attention Deficit Hyperactivity Disorder (ADHD) Kawasaki Disease Oct 6 Cerebral Palsy Childhood Leukemia Thurs, Oct 13 Midterm Exam Oct 20 GERD Constipation Inflammatory Bowel Diseases Short Bowel Syndrome

Course Outline: Date Oct 27 Content Common Cold Pediatric Fever Nov 3 Introduction to Neonatal Pharmacotherapy Respiratory Distress Syndrome Bronchopulmonary Dysplasia/Chronic Lung Disease Apnea of Prematurity Persistent Pulmonary Hypertension Patent Ductus Arteriosus Intraventricular Hemorrhage Hypoxic Ischemic Encephalopathy Nov 10 Blood Typing: ABO & Rh Factor Compatibility Neonatal Jaundice Neonatal Abstinence Syndrome Nov 17 Sepsis TORCH Infections Thurs, Nov 24 THANKSGIVING VACATION Dec 1 Necrotizing Enterocolitis (NEC) Congenital Heart Defects How to Feed A Baby Thurs, Dec 8 Holy Day (No Class) Thurs, Dec 15 Final Exam

Administrative Policies Governing All Courses Exam Tardiness Policy Missed Exam Policy Grade Appeal Policy Academic Integrity Policy Services for Students with Disabilities Audio/Visual Taping Policy Students are required to review these policies in their entirety Complete copies of or links to the policies may be found on the Student Services Blackboard site, Policy and Procedures