Extension Study 2, Self Reported, on-adjudicated Outcomes for s File ame A self report is only counted if the first report of that outcome occurred after the start of the extension 2 phase of the study. ID WHI Common ID Col#1 F33AGHOSP F33 Hospitalized Angina Col#2 0 o 20,966 94.0 1 Yes 1,350 6.0 F33AGHOSPDY Days enrollment to F33 Hospitalized Angina Col#3 1,350 20,966 4718 8724 6,354.037 875.388 F33COPD F33 COPD Col#4 COPD, emphysema, or chronic bronchitis 0 o 19,885 89.1 1 Yes 2,431 10.9 Usage otes: Only collected during the WHI Extension Study 2. F33COPDDY Days enrollment to F33 COPD Col#5 2,431 19,885 8744 6,395.095 902.367 F33AFIBHSP F33 Hospitalized Atrial Fibrillation Col#6 0 o 20,425 91.5 1 Yes 1,891 8.5 Usage otes: Only collected during the WHI Extension Study 2 F33AFIBHSPDY Days enrollment to F33 Hospitalized Atrial Fibrillation Col#7 1,891 20,425 8596 6,343.896 869.963 F33AFIBOP F33 Outpatient Atrial Fibrillation Col#8 0 o 21,194 95.0 1 Yes 1,122 5.0 F33AFIBOPDY Days enrollment to F33 Outpatient Atrial Fibrillation Col#9 1,122 21,194 4515 8730 6,561.827 904.683 F33MSC on-melanoma Skin Cancer Col#10 Page 1 of 7
Extension Study 2, Self Reported, on-adjudicated Outcomes for s File ame 0 o 21,942 98.3 1 Yes 374 1.7 F33MSCDY Days enrollment to F33 on-melanoma Skin Cancer Col#11 374 21,942 4742 8680 6,464.992 884.981 F33BKULEG F33 Broken Upper Leg Col#12 0 o 22,011 98.6 1 Yes 305 1.4 F33BKULEGDY Days enrollment to F33 Broken Upper Leg Col#13 305 22,011 4725 8412 6,464.584 821.180 F33BKPELV F33 Broken Pelvis Col#14 0 o 21,977 98.5 1 Yes 339 1.5 F33BKPELVDY Days enrollment to F33 Broken Pelvis Col#15 339 21,977 4748 8543 6,471.029 907.769 F33BKKEE F33 Broken Knee Col#16 0 o 21,983 98.5 1 Yes 333 1.5 F33BKKEEDY Days enrollment to F33 Broken Knee Col#17 333 21,983 4738 8352 6,365.225 861.545 F33BKSPIE F33 Broken Spine Col#18 0 o 21,620 96.9 1 Yes 696 3.1 F33BKSPIEDY Days enrollment to F33 Broken Spine Col#19 696 21,620 4717 8500 6,447.134 907.108 Page 2 of 7
Extension Study 2, Self Reported, on-adjudicated Outcomes for s File ame F33BKUARM F33 Broken Upper Arm Col#20 0 o 21,672 97.1 1 Yes 644 2.9 F33BKUARMDY Days enrollment to F33 Broken Upper Arm Col#21 644 21,672 4669 8727 6,414.171 900.254 F33BKLARM F33 Broken Lower Arm Col#22 0 o 21,488 96.3 1 Yes 828 3.7 F33BKLARMDY Days enrollment to F33 Broken Lower Arm Col#23 828 21,488 4655 8516 6,322.928 856.384 F33BKHAD F33 Broken Hand Col#24 0 o 22,132 99.2 1 Yes 184 0.8 F33BKHADDY Days enrollment to F33 Broken Hand Col#25 184 22,132 4760 8367 6,328.473 884.173 F33BKLLEG F33 Broken Lower Leg Col#26 0 o 21,791 97.6 1 Yes 525 2.4 F33BKLLEGDY Days enrollment to F33 Broken Lower Leg Col#27 525 21,791 4727 8734 6,350.726 901.750 F33BKFOOT F33 Broken Foot Col#28 0 o 21,915 98.2 1 Yes 401 1.8 F33BKFOOTDY Days enrollment to F33 Broken Foot Col#29 401 21,915 4732 8710 6,285.748 873.806 F33BKTAILB F33 Broken Tailbone Col#30 Page 3 of 7
Extension Study 2, Self Reported, on-adjudicated Outcomes for s File ame 0 o 22,209 99.5 1 Yes 107 0.5 F33BKTAILBDY Days enrollment to F33 Broken Tailbone Col#31 107 22,209 4752 8734 6,545.299 950.106 F33BKELBOW F33 Broken Elbow Col#32 0 o 22,147 99.2 1 Yes 169 0.8 F33BKELBOWDY Days enrollment to F33 Broken Elbow Col#33 169 22,147 4655 8378 6,363.793 851.309 F33BKOTHBX2 F33 Broken Other Bone Col#34 Broken other bone, Extension 2 definition. 0 o 20,885 93.6 1 Yes 1,431 6.4 Usage otes: This variable does not map to the Broken Other Bone (F33BKOTHB) variable collected prior to Extension Study 2, as the form question changed. F33BKOTHBX2DY Days enrollment to F33 Broken Other Bone Col#35 1,431 20,885 4712 8704 6,356.818 843.937 F33AYFXOHIP F33 Any on-hip Fracture Col#36 Any fracture except hip (includes other bone). 0 o 17,706 79.3 1 Yes 4,610 20.7 Usage otes: 1 if any of the non hip fractures were first reported in WHI extension study 2 F33AYFXOHIPD Y Days enrollment to F33 Any on-hip Fracture Col#37 4,610 17,706 4655 8734 6,316.186 869.148 F33HYST F33 Hysterectomy Ever Col#38 0 o 21,804 97.7 1 Yes 512 2.3 Page 4 of 7
Extension Study 2, Self Reported, on-adjudicated Outcomes for s File ame F33HYSTDY Days enrollment to F33 Hysterectomy Ever Col#39 512 21,804 4739 8674 6,333.785 838.102 F33OSTEOAR F33 Osteoarthritis Col#40 0 o 18,102 81.1 1 Yes 4,214 18.9 Usage otes: ot collected on all versions of F33. F33OSTEOARDY Days enrollment to F33 Osteoarthritis Col#41 4,214 18,102 4416 8742 6,445.475 906.240 F33ITPOLYP F33 Intestinal Polyps Col#42 0 o 20,455 91.7 1 Yes 1,861 8.3 F33ITPOLYPDY Days enrollment to F33 Intestinal Polyps Col#43 1,861 20,455 4533 8758 6,274.019 861.891 F33LUPUS F33 Lupus Col#44 0 o 22,200 99.5 1 Yes 116 0.5 F33LUPUSDY Days enrollment to F33 Lupus Col#45 116 22,200 4788 8434 6,427.707 936.981 F33PILLSHYP F33 Pills for Hypertension Col#46 0 o 20,248 90.7 1 Yes 2,068 9.3 F33PILLSHYPDY Days enrollment to F33 Pills For Hypertension Col#47 2,068 20,248 4435 8740 6,242.649 871.161 Page 5 of 7
Extension Study 2, Self Reported, on-adjudicated Outcomes for s File ame F33DIABTX F33 Diabetes Treated Col#48 0 o 20,470 91.7 1 Yes 1,846 8.3 Usage otes: Pills or insulin shots. F33DIABTXDY Days enrollment to F33 Diabetes Treated Col#49 1,846 20,470 8797 6,336.101 900.406 F33DIABISULI F33 Diabetes Insulin Col#50 0 o 21,705 97.3 1 Yes 611 2.7 F33DIABISULIDY Days enrollment to F33 Diabetes Insulin Col#51 611 21,705 4567 8585 6,429.113 897.874 F33DIABPILLS F33 Diabetes Pills Col#52 0 o 20,524 92.0 1 Yes 1,792 8.0 F33DIABPILLSDY Days enrollment to F33 Diabetes Pills Col#53 1,792 20,524 8797 6,339.857 902.439 F33DIABDIEX F33 Diabetes Diet and/or Exercise Col#54 0 o 19,595 87.8 1 Yes 2,721 12.2 Usage otes: F33DIABDIEXDY Days enrollment to Diabetes Diet and/or Exercise Col#55 2,721 19,595 4446 8779 6,350.822 910.206 F33PARKISOS F33 Parkinsons Col#56 0 o 22,052 98.8 1 Yes 264 1.2 Usage otes: Page 6 of 7
Extension Study 2, Self Reported, on-adjudicated Outcomes for s File ame F33PARKISOSDY Days enrollment to F33 Parkinsons Col#57 264 22,052 4668 8574 6,541.977 882.332 F33ALZHEIMERS F33 Alzheimers Col#58 0 o 19,940 89.4 1 Yes 2,376 10.6 Usage otes: F33ALZHEIMERSDY Days enrollment to F33 Alzheimers Col#59 2,376 19,940 8732 6,544.130 876.065 F33MACDEGE F33 Macular Degeneration Col#60 0 o 19,629 88.0 1 Yes 2,687 12.0 Usage otes: F33MACDEGEDY Days enrollment to F33 Macular Degeneration Col#61 2,687 19,629 8763 6,480.415 887.738 LAST33DY Days enrollment to last form 33/33D Col#62 Days from enrollment to last contact for outcomes information. 0 2934 8873 7,306.571 771.931 Usage otes: LAST33DY is calculated as the days from enrollment to the latest Form 33 during Extension Study 2. Because of the adjudication process, it is possible that there are some adjudicated events with days to event beyond LAST33DY. LAST33DY may be missing if the ppt had no form 33s entered for extension 2. F33HOSPX2 F33 Hospitalized During Extension Study 2 Col#63 0 o 8,801 39.4 1 Yes 13,515 60.6 F33HOSPTIMESX2 F33 umber of Hospitalizations During Extension Study 2 Col#64 0 one 8,801 39.4 1 One 5,204 23.3 2 Two 3,462 15.5 3 Three or more 4,849 21.7 Page 7 of 7