The Challenge of Malaria

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The Challenge of Malaria Prof. Awa-Marie Coll-Seck Executive Director of RBM Partnership Donors Forum (co-organized by MMV & CRESIB) Barcelona, 15 March 2010

A DECADE OF ROLLING BACK MALARIA: WHERE ARE WE? 1

Historic milestones in the fight against malaria (1998-2008) UN Secretary General's Special Envoy for malaria 1998 new funding for countries 2002 President's Malaria Initiative World Bank Booster 2005 Call for universal coverage by 2010 2008 Launch of fgmap 1999 2000 MMV Gates Foundation MDGs Abuja Summit 2003 RBM's architecture was developed 2007 G8 pledges Success in Countries ++ 2

More countries succeed in reducing malaria deaths and cases Malawi, Mozambique, Niger and Ethiopia: more than 40% decrease in under five mortality (UNICEF Sept 2009) Eritrea: 52% decrease in under five mortality (UNICEF Sept 2009) Equatorial Guinea: 63% reduction in allcause mortality in children under five since 2004 Zambia: 66% decline in malaria deaths; reached the 2010 target of a more than 50% reduction in malaria mortality Rwanda, Sao Tome and Principe and the compared to 2000 (WHO April 2009) island of Zanzibar achieved major reductions in malaria mortality. 3

CHALLENGES TO ACHIEVING THE 2010 TARGETS AND MDGs 4

Challenges at global level Key strategic challenges Funding gaps Keeping malaria high on the agenda Harmonization and alignment Strategic debates: -horizontal vs. vertical approach -debates on DDT use ACT and insecticide resistance Need for continued research and new tools 5

Global international financing increases (US$ million) 1.60 1,800 1500 1,500 1,299.70 1,200 900 600 439.63 608.26 701.26 300 249.11 0 2004 2005 2006 2007 2008 2009e The Global Fund PMI World Bank Other USAID Others 6

Global cost for malaria control and elimination R&D will cost additional $US 750 to 900 million a year 7

Global research and development costs US$ billions Global research & development costs (~ $750M $900M / year) 7 New vaccines, drugs, vector control and diagnostics 6 5 4 3 2 1 0 Global implementation costs (~ $5B / yr for next 10 yrs) Prevention: LLINs, IRS and IPTp Case management: Drugs, diagnostics and severe case mgt Country program costs: infrastructure / institutional strengthening, M&E, operational research, training and community health workers. 2008 2010 2014 2015 2020 20252026 2030 2032035 2038 2040 Source: GMAP costing model 8

Estimated annual global resource needs for malaria control and current global malaria commitments from Global Fund, World Bank, and US-PMI US dollars (billion) Source: Global Malaria Action Plan (RBM 2008), Global Fund, World Bank and US-PMI 9

More investment in R&D for malaria 4 consortia focus on developing new tools Vector control Diagnosticsi Drugs Vaccines 10

Strategic debate: horizontal vs. vertical approach Health systems strengthening and disease control are complementary and interdependent Effective and sustainable malaria control efforts depend on strong health systems Strong health systems are needed to ensure sustainable access to prevention e.g. IPTp through ANC clinics, effective diagnosis and treatment (ACTs) Malaria control programmes strengthen th health systems DISEASE CONTROL HEALTH SYSTEMS Ehi Ethiopia: i building a human resources capacity at community level Tanzania, Zambia, etc.: freeing overburdened health facilities to tackle other life-threatening t i illnesses. 11

Strategic debates: DDT use The Stockholm Convention on Persistent Organic Pollutants allows the use of DDT for disease vector control, within the recommendations and guidelines of WHO until locally effective and affordable substitutes are available. The ongoing g debate on use among public health specialists and policy- makers influences: the production and availability of DDT for vector control countries' decision to deploy DDT A need to secure: Investment in research for alternatives 12

Challenges at country level Recent inputs Meeting of African ministers in Geneva: May 2009 Data from country roadmaps for 47 African countries and territories Partner publications Information shared in key meetings WHO/ UNICEF data 13

Challenges at country level Weak health systems Low community awareness and participation 14

ACTs: distribution challenges Anti-malarial monotherapies still exceed ACTs in the private and public sectors. Relative Volumes of Antimalarials Distributed by Sector and Drug Type 100 90 80 Malaria treatments are currently obtained mainly through the private sector. Almost 25% of all malaria treatments distributed through the private sector in DRC are oral artemisinin monotherapies. 70 60 % 50 40 30 20 10 0 Public Private Public Private Public Private Public Private Public Private Public Private Public Private Benin Cambodia DRC Madagascar Nigeria Uganda Zambia First line ACTs Other ACTs Non-artemisinin monotherapies Oral artemisinin monotherapy www.actwatch.info 11/20/2009 Source: ACTWatch 27 15

Fluctuations in donor funding for countries Total disbursements for malaria control OECD database for selected countries 2003 to 2007 40 35 Angola 30 Burkina Faso Burundi 25 Dem Rep Congo Ghana 20 Madagascar 15 Senegal Tanzania 10 Uganda Zambia 5 0 2003 2004 2005 2006 2007 2008 Source: OECD database, analysis by MACEPA 16

PARTNERSHIP INITIATIVES TO ADDRESS CHALLENGES 17

Uniting partners to overcome challenges Targets: Innovative financing mechanisms By 2010 : universal coverage By 2015 : reduce deaths to near zero 2015 and beyond : sustain gains and work towards elimination Access to GF resources: TA for country applications Expansion of donors base VPP, AMFm, SMS for life UAM, ALMA MalERA 18

OVERCOMING THESE CHALLENGES WILL HELP US REACH THE MALARIA TARGETS 19