Alertness and Sleep Health Management Research & Technology Strategic Opportunity Overview (V2, updated 11/9/18) Myron Kassaraba, Managing Director MJK Partners, LLC myron@mjkpartners.com Tel: 617-448-9558 Stephen Pittman SD Pittman & Co. LLC stephen@sdpittman.com Tel: 617-529-5135 1 MJK Partners, LLC, 2018 Copyright 2012 Pluritas, LLC.
Opportunity MJK Partners has been retained by Management and the Board of Alertness CRC (Alert) to explore strategic opportunities for the company. Alert is 5 years into a 7 year funding commitment and is open to a range of options including investment, merger/combination, or sale. This document provides background on the CRC and a general overview of the opportunity. Additional public information including a Supplement: Projects and Outputs as well as specific Output Profiles for each key project are available at: https://mjkpartners.com/opportunities/alertnesscrc/ To learn more and discuss this opportunity contact: Myron Kassaraba MJK Partners, LLC Tel. 617-902-0639 Myron@mjkpartners.com 2 MJK Partners, LLC, 2018 2017 2018 2
About the Alertness CRC Over US $75 million in cash and other resources invested by industry, academia and government. Third party products using Alertness CRC resources to-date: Philips SmartSleep Opturion AlertSafe Workforce Management Software Solemma ALPHA Lighting Software Flexible collaborative structure with independent governance and robust IP management processes. The Alertness CRC has developed a portfolio of novel algorithms, technologies and product concepts in sleep health that are primed for commercialization. Proven network of investigators, institutions and collaborators in an ideal market to validate health technologies & willingness-to-pay. 3 MJK MJK Partners, Partners, LLC, LLC, 2017 2018 3
Overview Alertness CRC is a world-class research and development organization producing cutting-edge technologies and capabilities in the area of sleep and alertness. Sleep and alertness are massive public health, safety and productivity issues. In Australia alone, the total cost of inadequate sleep was estimated to be $66.3 billion in 2016-17 1. As an Australian Cooperative Research Centre, the Alertness CRC brings together expert knowledge, state of the art technologies and effective end user partnerships to deliver innovation in sleep health to the market. The pursuit of targeted outcomes for the private sector through industry-led research has delivered key capabilities, products, and technologies that are primed for commercialisation. 1. Sleep Health Foundation, Asleep on the Job: Costs of Inadequate Sleep in Australia. Deloitte Access Economics, 2017 4 MJK Partners, LLC, 2017 2018 4
Technology and Development End Users Safety Critical Industry Settings Policy, Regulatory and Insurance Stakeholder Collaborators Over thirty participant organisations driving innovation and establishing commercialisation pathways Broad range of technology developers with market knowledge and reach. International presence through Philips Respironics with global deployment capabilities. High risk operational settings for field testing. SME s seeking capacity and relevance in an international market. 5 MJK Partners, LLC, 2017 2018 Research and Translation Capacity Regulators that want to drive research and enable change. Academic expertise, clinical trial networks and sleep health advocacy mechanisms. 5
World Class Team of Investigators Dr. Steven Lockley* Dr. Svetlana Postnova Professor Doug McEvoy Professor Karen Reynolds Professor Ron Grunstein* Assoc. Prof. Clare Anderson Professor Shantha Rajaratnam* Professor Mark Wallace Professor Mark Howard 6 * Program Leaders For more information on the team see: http://www.alertnesscrc.com/research-leadership MJK Partners, LLC, 2017 2018 6
CRC Ecosystem The Alertness CRC team of investigators are engaged in leading-edge sleep and alertness research and product development focused on solutions for key challenges for the consumer, enterprise and clinical markets. 7 MJK MJK Partners, Partners, LLC, LLC, 2017 2018
Core Capabilities The Alertness CRC and AlertSafe portfolio and approach is underpinned by: An extensive and unique dataset; A validated biophysical model that interprets subjective and objective data to measure and predict sleep duration / efficiency, circadian state and alertness; and, State of the art data science capabilities that can drive further innovation. 8 MJK Partners, LLC, 2017 2018 8
CRC Platform 9 MJK Partners, LLC, 2017 2018 9
CRC Areas of Focus Personal Sleep Health Management Sleep management mobile application for insomnia diagnosis and treatment Sleep optimization biofeedback device Workforce Management Smart rostering and scheduling for employers Sleep optimization tools and mobile applications for shift workers Fatigue Risk Management & Fitness for Duty Identification of pre-disposition to fatigue, lack of sleep and alertness using novel biomarkers & metabolites and other objective measures. Clinical Sleep Disorder Screening 10 MJK MJK Partners, Partners, LLC, LLC, 2017 2018 10
Core IP/Knowhow The CRC s efforts are based on these core building blocks. Biophysical Model of Arousal Dynamics (MAD) a validated biophysical model that predicts alertness, sleep, and circadian dynamics under a variety of conditions, including normal daytime activities, shiftwork, and jetlag. Sleep-Wake Management (SWM) Algorithm An evidence-based algorithm that identifies sleep/wake patterns Metabolite Biomarkers A patent pending objectively measured sleep biomarker with biological characteristics to determine how long and individual has been awake, or whether they have been awake for a specified period. Extensive Proprietary Dataset Developed over 5+ years of research, the CRC s dataset covers a wide range of factors and variables critical to the assessment of alertness, fatigue and sleep. More details on these Outputs - see Supplement and Profiles at : https://mjkpartners.com/opportunities/alertnesscrc/ 11 MJK MJK Partners, Partners, LLC, LLC, 2017 2018 11
Portfolio of Key Outputs Alertness CRC has developed products and technologies in these key areas: Sleep health management decision support tools*. Shift work / lifestyle management software. Personalised sleep disorder treatment*. Enterprise work scheduling software tools. Alertness testing and fitness for duty monitoring. Biological markers of alertness and sleep state*. Advances in clinical sleep disorder screening. These outputs are in various stages from research & development to active commercialization efforts. * Patent pending More details on these Outputs - see Supplement and Profiles at : https://mjkpartners.com/opportunities/alertnesscrc/ 12 MJK Partners, LLC, 2017 2018 12
Specific Outputs More details on these Outputs - see Supplement and Profiles at : https://mjkpartners.com/opportunities/alertnesscrc/ 13 MJK MJK Partners, Partners, LLC, LLC, 2017 2018 13
Partnership Opportunities Seeking organizations with interests in the work of the CRC and related commercialization and investment opportunities in: Consumer sleep health management applications Workforce management, scheduling & rostering Novel biomarkers of alertness and sleep state Partners/licensees can leverage key product concepts and components, make use of or integrate with AlertSafe TM branded systems and gain access to the CRC s critical sleep health management/wellness ecosystem capabilities and expertise. 14 MJK Partners, LLC, 2017 2018 14
NOTICE THIS PRESENTATION DOES NOT CONSTITUTE AN OFFER FOR SALE OF ASSETS OR SECURITIES FOR ALERTNESS CRC OR AN OFFER FOR, OR SOLICITATION OF, A LICENSE OF ANY KIND. IN MAKING A DECISION REGARDING THE ALERNESS CRC OPPORTUNITY, POTENTIAL PURCHASERS MUST RELY ON THEIR OWN EXAMINATION OF THE INTELLECTUAL PROPERTY RIGHTS AND OTHER ASSETS INCLUDING BUT NOT LIMITED TO THE TITLE, VALUE, MERITS AND RISKS INVOLVED. MJK PARTNERS, LLC (MJK PARTNERS) MAKES NO REPRESENTATION CONCERNING THE VALIDITY OF THE INTELLECTUAL PROPERTY HEREIN. ADDITIONALLY, THESE MATERIALS ARE SOLELY ATTRIBUTABLE TO MJK PARTNERS AND DO NOT NECESSARILY REPRESENT THE VIEWS OR OPINIONS OF ALERTNESS CRC. NOTHING IN THIS DOCUMENT SHALL CONSTITUTE OR BE INTERPRETED AS LEGAL ANALYSIS REGARDING THE SCOPE OF INTELLECTUAL PROPERTY RIGHTS. SIMILARLY, NOTHING INCLUDED IN THIS DOCUMENT SHALL BE USED TO INTERPRET, DEFINE, OR OTHERWISE LIMIT THE SCOPE AFFORDED THE ASSOCIATED INTELLECTUAL PROPERTY RIGHTS. Contacts: Myron Kassaraba Managing Director MJK Partners, LLC myron@mjkpartners.com Tel: 617-902-0639 Stephen Pittman Principal SD Pittman & Co. LLC stephen@sdpittman.com Tel: 617-529-5135 15 MJK MJK Partners, Partners, LLC, LLC, 2017 2018 15